AU2016207010A1 - Micro-droplet delivery device and methods - Google Patents

Micro-droplet delivery device and methods Download PDF

Info

Publication number
AU2016207010A1
AU2016207010A1 AU2016207010A AU2016207010A AU2016207010A1 AU 2016207010 A1 AU2016207010 A1 AU 2016207010A1 AU 2016207010 A AU2016207010 A AU 2016207010A AU 2016207010 A AU2016207010 A AU 2016207010A AU 2016207010 A1 AU2016207010 A1 AU 2016207010A1
Authority
AU
Australia
Prior art keywords
micro
droplets
actuator
aperture
acoustic cavity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2016207010A
Other languages
English (en)
Inventor
Yehuda Ivri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kedalion Therapeutics Inc
Original Assignee
Kedalion Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kedalion Therapeutics Inc filed Critical Kedalion Therapeutics Inc
Publication of AU2016207010A1 publication Critical patent/AU2016207010A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0026—Ophthalmic product dispenser attachments to facilitate positioning near the eye
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body
    • A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body
    • A61M35/10—Wearable devices, e.g. garments, glasses or masks
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
    • F04B43/04—Pumps having electric drive
    • F04B43/043—Micropumps
    • F04B43/046—Micropumps with piezoelectric drive
    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C11/00—Non-optical adjuncts; Attachment thereof
    • G02C11/10—Electronic devices other than hearing aids
    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10N—ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10N30/00—Piezoelectric or electrostrictive devices
    • H10N30/20—Piezoelectric or electrostrictive devices with electrical input and mechanical output, e.g. functioning as actuators or vibrators
    • H10N30/206—Piezoelectric or electrostrictive devices with electrical input and mechanical output, e.g. functioning as actuators or vibrators using only longitudinal or thickness displacement, e.g. d33 or d31 type devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Otolaryngology (AREA)
  • Acoustics & Sound (AREA)
  • Optics & Photonics (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Electrotherapy Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Eyeglasses (AREA)
  • Reciprocating Pumps (AREA)
  • Medicinal Preparation (AREA)
AU2016207010A 2015-01-12 2016-01-11 Micro-droplet delivery device and methods Abandoned AU2016207010A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562125073P 2015-01-12 2015-01-12
US62/125,073 2015-01-12
PCT/US2016/012903 WO2016115050A1 (en) 2015-01-12 2016-01-11 Micro-droplet delivery device and methods

Publications (1)

Publication Number Publication Date
AU2016207010A1 true AU2016207010A1 (en) 2017-08-03

Family

ID=56366701

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2016207010A Abandoned AU2016207010A1 (en) 2015-01-12 2016-01-11 Micro-droplet delivery device and methods

Country Status (8)

Country Link
US (3) US10624781B2 (enExample)
EP (1) EP3244851B1 (enExample)
JP (1) JP2018510668A (enExample)
KR (1) KR101984116B1 (enExample)
CN (2) CN113230021A (enExample)
AU (1) AU2016207010A1 (enExample)
CA (1) CA2973471A1 (enExample)
WO (1) WO2016115050A1 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3244851B1 (en) 2015-01-12 2024-10-16 Bausch + Lomb Ireland Limited Micro-droplet delivery device
KR20170135862A (ko) * 2015-04-10 2017-12-08 켄달리온 테라퓨틱스 인코포레이티드 교체 가능한 앰플을 갖는 압전 디스펜서
CN109906120A (zh) * 2017-01-20 2019-06-18 科达莱昂治疗公司 压电流体分配器
WO2018221687A1 (ja) * 2017-05-31 2018-12-06 株式会社坪田ラボ モイスチャーミストの噴霧装置及び噴霧方法
KR102643190B1 (ko) 2017-06-10 2024-03-04 아이노비아 인코포레이티드 유체를 취급하기 위한, 그리고 눈에 유체를 전달하기 위한 디바이스들
CN109674576B (zh) * 2017-10-19 2024-02-27 深圳市启明医药科技有限公司 流体供应单元及微液滴喷射驱动装置、发生装置
WO2019113483A1 (en) 2017-12-08 2019-06-13 Kedalion Therapeutics, Inc. Fluid delivery alignment system
BR112020018900A2 (pt) * 2018-03-21 2021-02-09 Tsubota Laboratory, Inc. dispositivo e método não invasivo de reforço de córnea e esclera
US12350194B1 (en) 2018-04-12 2025-07-08 Bausch + Lomb Ireland Limited Topical ocular delivery of fluids with controlled mass dosing and wireless communication
WO2019200121A1 (en) 2018-04-12 2019-10-17 Kedalion Therapeutics, Inc. Topical ocular delivery methods and devices for use in the same
EP3817696B8 (en) * 2018-07-03 2024-12-11 Bausch + Lomb Ireland Limited Topical ocular delivery devices
US10292998B1 (en) 2018-08-07 2019-05-21 Ahad Mahootchi Compositions and methods for prevention and treatment of eye infections
US12097145B2 (en) 2019-03-06 2024-09-24 Bausch + Lomb Ireland Limited Vented multi-dose ocular fluid delivery system
US11679028B2 (en) 2019-03-06 2023-06-20 Novartis Ag Multi-dose ocular fluid delivery system
FI128476B (en) * 2019-05-31 2020-06-15 Icare Finland Oy EQUIPMENT FOR THE OPHTHOMMOMETER AND ASSOCIATED SYSTEM, METHOD, AND USE
JP7116959B2 (ja) * 2019-07-19 2022-08-12 日本電信電話株式会社 情動制御装置、その方法、およびプログラム
US12496218B1 (en) 2019-11-12 2025-12-16 Bausch + Lomb Ireland Limited Fractionated topical ocular drug delivery methods and devices for use in the same
WO2021119513A1 (en) 2019-12-11 2021-06-17 Eyenovia, Inc. Systems and devices for delivering fluids to the eye and methods of use
EP4120973B1 (en) 2020-04-17 2026-06-10 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system having a collapsible liquid reservoir
CA3180199A1 (en) 2020-04-17 2021-10-21 Yehuda Ivri Hydrodynamically actuated preservative free dispensing system
US11938057B2 (en) 2020-04-17 2024-03-26 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system
US12290472B2 (en) 2020-04-17 2025-05-06 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system
CN114948410B (zh) * 2021-02-26 2025-10-14 天津市眼科医院 一种治疗用的眼镜及用于眼镜的声流体微型泵
JP7558891B2 (ja) * 2021-05-28 2024-10-01 株式会社ジンズホールディングス アイウエア及びカートリッジ
JP7558892B2 (ja) * 2021-05-28 2024-10-01 株式会社ジンズホールディングス カートリッジ製品及びカバー部材
US11647942B1 (en) 2022-03-22 2023-05-16 Stat Capsule Inc. Device for monitoring and treating bradyarrhythmia
US11471657B1 (en) 2022-03-22 2022-10-18 Stat Capsule Inc. Device and method for monitoring and treating advanced bradycardia
DE102022116282A1 (de) 2022-06-29 2024-01-04 EyeNeb GmbH Vorrichtung zum Benetzen des Auges und Verfahren dazu
CN116626916B (zh) * 2023-05-30 2025-11-18 温州市嘉法眼镜有限公司 智能雾化近视防控眼镜
WO2025003273A1 (en) 2023-06-27 2025-01-02 EyeNeb GmbH Improved device for wetting the eye and method therefor
US20250120824A1 (en) * 2023-10-17 2025-04-17 Elevation Spine, Inc. Implant inserter assembly

Family Cites Families (254)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1575050A1 (de) 1966-01-12 1972-04-13 Misto Gen Equipment Co Ultraschall-Nebelerzeugungsgeraet
US3640274A (en) 1966-11-04 1972-02-08 Colgate Palmolive Co Eye-spraying device having mirror
US3934585A (en) 1970-08-13 1976-01-27 Maurice David M Method and apparatus for application of eye drops
US3779245A (en) 1972-06-13 1973-12-18 R Windsor Device for applying materials to the area of the eye
US3812854A (en) 1972-10-20 1974-05-28 A Michaels Ultrasonic nebulizer
DE2445791C2 (de) 1974-09-25 1984-04-19 Siemens AG, 1000 Berlin und 8000 München Ultraschall-Flüssigkeitszerstäuber
US3976072A (en) * 1975-09-03 1976-08-24 The United States Of America As Represented By The Secretary Of The Department Of Health, Education And Welfare Blink-operated extracorporeal tear duct
US4159803A (en) 1977-03-31 1979-07-03 MistO2 Gen Equipment Company Chamber for ultrasonic aerosol generation
US4338576A (en) 1978-07-26 1982-07-06 Tdk Electronics Co., Ltd. Ultrasonic atomizer unit utilizing shielded and grounded elements
DE2849493C2 (de) 1978-11-15 1982-01-14 Carl Heyer Gmbh, Inhalationstechnik, 5427 Bad Ems In der Hand zu haltender Aerosolspender
DE2902624C2 (de) 1979-01-24 1985-10-10 Pfeiffer Zerstäuber Vertriebsgesellschaft mbH & Co KG, 7760 Radolfzell Ausgabepumpe
DE7917568U1 (de) 1979-06-19 1979-09-20 Bosch-Siemens Hausgeraete Gmbh, 7000 Stuttgart Inhalationsgeraet
US4352459A (en) 1979-11-13 1982-10-05 Sono-Tek Corporation Ultrasonic liquid atomizer having an axially-extending liquid feed passage
US4465234A (en) 1980-10-06 1984-08-14 Matsushita Electric Industrial Co., Ltd. Liquid atomizer including vibrator
US4632311A (en) 1982-12-20 1986-12-30 Matsushita Electric Industrial Co., Ltd. Atomizing apparatus employing a capacitive piezoelectric transducer
US4655393A (en) 1983-01-05 1987-04-07 Sonotek Corporation High volume ultrasonic liquid atomizer
EP0173334B1 (en) 1984-08-29 1989-11-23 Omron Tateisi Electronics Co. Ultrasonic atomizer
GB2200211B (en) 1986-12-08 1991-01-16 Fuji Electric Co Ltd Vibration-type transducer
US4976259A (en) 1986-12-22 1990-12-11 Mountain Medical Equipment, Inc. Ultrasonic nebulizer
US4952581A (en) 1987-04-03 1990-08-28 The Trustees Of Columbia University In The City Of New York Use of a prostaglandin in combination with an adrenergic blocking agent for reduction of intraocular pressure
US4850534A (en) 1987-05-30 1989-07-25 Tdk Corporation Ultrasonic wave nebulizer
US4981625A (en) 1988-03-14 1991-01-01 California Institute Of Technology Monodisperse, polymeric microspheres produced by irradiation of slowly thawing frozen drops
US4882150A (en) 1988-06-03 1989-11-21 Kaufman Herbert E Drug delivery system
US5025957A (en) 1988-10-07 1991-06-25 Ryder International Corp. Liquid dispenser nozzle assembly
EP0563120B1 (en) 1990-12-17 1997-10-01 Minnesota Mining And Manufacturing Company Inhaler
US5171306A (en) 1991-03-13 1992-12-15 Vo Van T Eyedrop delivery system
US6629646B1 (en) 1991-04-24 2003-10-07 Aerogen, Inc. Droplet ejector with oscillating tapered aperture
US5938117A (en) 1991-04-24 1999-08-17 Aerogen, Inc. Methods and apparatus for dispensing liquids as an atomized spray
US5232363A (en) 1991-06-11 1993-08-03 Eran Meller Scaler with improved vibration characteristics
GB9114080D0 (en) 1991-06-28 1991-08-14 Weston Terence E Atomising valve
US5549249A (en) 1991-12-13 1996-08-27 Contico International, Inc. Fluid spinner and nozzle head assembly with controlled fluid flood path
US5368582A (en) * 1992-08-10 1994-11-29 The Schepens Eye Research Institute Method and apparatus for introducing fluid material into an eye
ES2105333T3 (es) 1992-10-13 1997-10-16 Alcon Lab Inc Combinaciones de prostaglandinas y derivados de clonidina para el tratamiento del glaucoma.
GB2272389B (en) 1992-11-04 1996-07-24 Bespak Plc Dispensing apparatus
WO1994020875A2 (en) 1993-03-03 1994-09-15 Street Graham S B Method and apparatus for image alignment
EP0622035B1 (en) 1993-04-30 1999-03-03 Henlopen Manufacturing Co., Inc. Applicator system for fluid cosmetic material
JP2857253B2 (ja) 1993-12-22 1999-02-17 メルク エンド カンパニー インコーポレーテッド 眼科用パッケージおよび滴下装置
GB9405952D0 (en) 1994-03-25 1994-05-11 Zeneca Ltd Aqueous ophthalmic sprays
WO1996000050A1 (en) 1994-06-23 1996-01-04 R.P. Scherer Corporation Ocular treatment device
JPH08251948A (ja) 1995-03-15 1996-09-27 Olympus Optical Co Ltd 摺動部材
US6085740A (en) 1996-02-21 2000-07-11 Aerogen, Inc. Liquid dispensing apparatus and methods
US6427682B1 (en) 1995-04-05 2002-08-06 Aerogen, Inc. Methods and apparatus for aerosolizing a substance
US5657926A (en) 1995-04-13 1997-08-19 Toda; Kohji Ultrasonic atomizing device
US5828394A (en) 1995-09-20 1998-10-27 The Board Of Trustees Of The Leland Stanford Junior University Fluid drop ejector and method
US5627611A (en) * 1995-12-29 1997-05-06 Scheiner; Stanley A. Artificial tears
FR2746657B1 (fr) 1996-03-29 1998-06-26 Sofab Dispositif antibacterien de pulverisation d'un produit liquide
US5958342A (en) * 1996-05-17 1999-09-28 Incyte Pharmaceuticals, Inc. Jet droplet device
US5692651A (en) 1996-06-06 1997-12-02 Owens-Illinois Closure Inc. Self-sealing dispensing closure
US5881956A (en) 1996-08-08 1999-03-16 Ben Z. Cohen Microdispensing ophthalmic pump
US6024717A (en) 1996-10-24 2000-02-15 Vibrx, Inc. Apparatus and method for sonically enhanced drug delivery
US5960224A (en) 1996-12-26 1999-09-28 Fuji Photo Film Co., Ltd. Image forming apparatus and fluid injecting apparatus
US6065623A (en) 1998-02-13 2000-05-23 Crown Cork & Seal Technologies Corporation Closure with lenticular lens insert
DE19823719B4 (de) * 1998-05-27 2011-12-15 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren zum Aufkonzentrieren von Substanzen
JP3055480U (ja) * 1998-07-01 1999-01-12 孟 ▲じゃ−▼ 康 軽量型目薬液噴射器
US6109355A (en) 1998-07-23 2000-08-29 Pes Limited Tool string shock absorber
US6070575A (en) * 1998-11-16 2000-06-06 Aradigm Corporation Aerosol-forming porous membrane with certain pore structure
US6232129B1 (en) * 1999-02-03 2001-05-15 Peter Wiktor Piezoelectric pipetting device
US6196218B1 (en) 1999-02-24 2001-03-06 Ponwell Enterprises Ltd Piezo inhaler
US6254860B1 (en) 1999-04-13 2001-07-03 Allergan Sales, Inc. Ocular treatment using cyclosporin-A derivatives
US6730066B1 (en) 1999-08-03 2004-05-04 Pharmacia Ab Liquid delivery container
US6235177B1 (en) 1999-09-09 2001-05-22 Aerogen, Inc. Method for the construction of an aperture plate for dispensing liquid droplets
US6302101B1 (en) 1999-12-14 2001-10-16 Daniel Py System and method for application of medicament into the nasal passage
US20010035184A1 (en) * 1999-12-17 2001-11-01 Carlos Schuler Systems and methods for treating packaged powders
WO2001046134A1 (en) 1999-12-22 2001-06-28 Alcon Universal Ltd. 6-KETO PROSTAGLANDIN F1α AND ANALOGS FOR TREATING DRY EYE
US7160511B2 (en) * 2000-02-18 2007-01-09 Olympus Corporation Liquid pipetting apparatus and micro array manufacturing apparatus
US7867186B2 (en) 2002-04-08 2011-01-11 Glaukos Corporation Devices and methods for treatment of ocular disorders
US7080644B2 (en) * 2000-06-28 2006-07-25 Microdose Technologies, Inc. Packaging and delivery of pharmaceuticals and drugs
US6273092B1 (en) 2000-09-22 2001-08-14 Gerard M. Nolan Methods for treating various eye disorders
DE10052819B4 (de) * 2000-10-24 2004-02-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Pipettensystem und Pipettenarray sowie Verfahren zum Befüllen eines Pipettensystems
US6722364B2 (en) * 2001-01-12 2004-04-20 Becton, Dickinson And Company Medicament inhalation delivery devices and methods for using the same
US20020124843A1 (en) * 2001-02-01 2002-09-12 Skiba Jeffry B. Eye medication delivery system
US6758837B2 (en) 2001-02-08 2004-07-06 Pharmacia Ab Liquid delivery device and method of use thereof
WO2002072169A2 (en) 2001-03-09 2002-09-19 Antares Pharma, Inc. Ocular drug delivery nebulizer
WO2002074372A2 (en) 2001-03-15 2002-09-26 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Nebulizer having cooling chamber
ATE476751T1 (de) * 2001-03-29 2010-08-15 Wisconsin Alumni Res Found Piezoelektrisch geladene tröpfchenquelle
US7496401B2 (en) 2001-04-06 2009-02-24 Mattioli Engineering Ltd Method and apparatus for skin absorption enhancement and transdermal drug delivery
DE10154526B4 (de) 2001-06-12 2007-02-08 Physik Instrumente (Pi) Gmbh & Co Piezoelektrisches Stellelement
JP2003063576A (ja) 2001-06-15 2003-03-05 Taisei Kako Co Ltd 分与容器
US6783035B2 (en) * 2001-07-19 2004-08-31 Valois S.A.S. Fluid product dispenser
US6723077B2 (en) * 2001-09-28 2004-04-20 Hewlett-Packard Development Company, L.P. Cutaneous administration system
JP4761709B2 (ja) 2002-01-15 2011-08-31 エアロジェン，インコーポレイテッド エアロゾル発生器を作動するための方法およびシステム
US6869275B2 (en) 2002-02-14 2005-03-22 Philip Morris Usa Inc. Piezoelectrically driven fluids pump and piezoelectric fluid valve
JP4100202B2 (ja) * 2002-03-18 2008-06-11 セイコーエプソン株式会社 圧電アクチュエータ、及び、液体噴射ヘッド
US20040039355A1 (en) 2002-08-26 2004-02-26 Gonzalez Jose M. Fluid dispensing devices and methods
US20050261641A1 (en) 2002-09-26 2005-11-24 Warchol Mark P Method for ophthalmic administration of medicament
KR100452849B1 (ko) * 2002-10-17 2004-10-14 삼성전자주식회사 마이크로 분사기를 이용한 프린터 헤드
WO2004038460A2 (en) 2002-10-23 2004-05-06 Abdulla Nael A Aqueous ophthalmic spray and method for delivery
US6814265B2 (en) 2003-03-06 2004-11-09 Alcon, Inc. Device for dispensing fluid medicine
US7201732B2 (en) 2003-04-10 2007-04-10 Hewlett-Packard Development Company, L.P. Dispensing method and device for delivering material to an eye
EP1468748A1 (en) 2003-04-15 2004-10-20 Microflow Engineering SA Low-cost liquid droplet spray device and nozzle body
WO2004099059A2 (en) * 2003-04-30 2004-11-18 Aurora Discovery, Inc. Method and system for precise dispensation of a liquid
US8012136B2 (en) 2003-05-20 2011-09-06 Optimyst Systems, Inc. Ophthalmic fluid delivery device and method of operation
WO2004103478A1 (en) 2003-05-20 2004-12-02 Collins James F Ophthalmic drug delivery system
US8021334B2 (en) 2004-05-30 2011-09-20 Nilimedix Ltd. Drug delivery device and method
US8128606B2 (en) 2003-07-03 2012-03-06 Hewlett-Packard Development Company, L.P. Ophthalmic apparatus and method for administering agents to the eye
DE10337484B4 (de) * 2003-08-14 2005-05-25 Zengerle, Roland, Prof. Dr. Mikrodosiervorrichtung und Verfahren zur dosierten Abgabe von Flüssigkeiten
US20050059583A1 (en) 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
AU2004287875B2 (en) 2003-11-05 2011-06-02 Bausch + Lomb Ireland Limited Modulators of cellular adhesion
DE102004006452B4 (de) 2004-02-05 2006-04-20 Ing. Erich Pfeiffer Gmbh Mikrodosiervorrichtung
CN101018580B (zh) 2004-02-06 2010-07-14 微计量技术有限公司 与吸入装置一起使用的泡罩包装
CA2557020A1 (en) 2004-02-24 2005-09-01 Boehringer Ingelheim International Gmbh Atomiser
CA2561845C (en) 2004-04-02 2014-03-25 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Aerosol delivery systems and methods
US20050240162A1 (en) 2004-04-21 2005-10-27 Wen-Pin Chen Eye treatment device
EP1755732A4 (en) 2004-04-23 2008-01-16 Mystic Pharmaceuticals Inc DISPENSING SYSTEM FOR MEDICINAL PRODUCTS IN SEVERAL SINGLE DOSES
GB0410712D0 (en) * 2004-05-13 2004-06-16 Novartis Ag Organic compounds
US7665923B2 (en) 2004-09-27 2010-02-23 Medical Instill Technologies, Inc. Laterally-actuated dispenser with one-way valve for storing and dispensing metered amounts of substances
US20060069358A1 (en) * 2004-09-29 2006-03-30 Gerondale Scott J Controlled drop dispensing units
CA2582374A1 (en) 2004-10-04 2006-04-20 Qlt Usa, Inc. Ocular delivery of polymeric delivery formulations
GB2434548B (en) 2004-11-22 2009-04-08 Intelliject Inc Devices, systems, and methods for medicament delivery
EP1828601A1 (en) * 2004-12-22 2007-09-05 Matsushita Electric Works, Ltd. Liquid discharge control apparatus
US20080233053A1 (en) 2005-02-07 2008-09-25 Pharmalight Inc. Method and Device for Ophthalmic Administration of Active Pharmaceutical Ingredients
SI1881823T1 (sl) 2005-05-17 2015-04-30 Sarcode Bioscience Inc. Sestavki in postopki za zdravljenje bolezni oäśesa
ES2654209T5 (es) 2005-05-18 2021-09-30 Visual Physics Llc Sistema de presentación de imágenes y de seguridad micro-óptico
NZ563360A (en) 2005-05-25 2011-04-29 Aerogen Inc Aerosolising liquid using an apertured membrane aligned within a peizoelectric ring
WO2006129305A2 (en) 2005-06-02 2006-12-07 Ads & B Investmentfund L.P A vibrating device for treating nasal congestion and sinusitis symptoms and method thereof
US10646668B2 (en) 2005-06-02 2020-05-12 Respinova Ltd. Pulsating inhaler and a method of treating upper respiratory disorders
DE102005025640A1 (de) * 2005-06-03 2006-12-07 Scienion Ag Mikrodispenser und zugehöriges Betriebsverfahren
DE102005043034A1 (de) * 2005-09-09 2007-03-15 Siemens Ag Vorrichtung und Verfahren zur Bewegung einer Flüssigkeit
EP1779933A1 (en) 2005-10-26 2007-05-02 The Procter and Gamble Company Dispenser for a liquid
US7874467B2 (en) 2005-11-03 2011-01-25 Reseal International Limited Partnership Metered drop push button dispenser system
US20070195151A1 (en) * 2006-02-23 2007-08-23 Anderson Frank E Hand-held ink jet pen
FR2897599B1 (fr) 2006-02-23 2010-08-27 Rexam Pharma Ensemble de conditionnement et de distribution de liquide.
EP2016778A4 (en) * 2006-05-11 2010-07-28 Eran Eilat EYE MEDICINES DONOR
US20070268340A1 (en) * 2006-05-17 2007-11-22 Bruno Dacquay Ophthalmic Injection System and Method Using Piezoelectric Array
DE102006026786A1 (de) 2006-06-07 2007-12-13 Joachim Kern Dosierinhalator
US8048047B2 (en) 2006-06-23 2011-11-01 Novartis Ag Surgical cassette with improved air filtering
US20080039807A1 (en) 2006-08-08 2008-02-14 Jerrold Scott Pine Ophthalmic Drug Dispensing Tip
DE102006040316B4 (de) 2006-08-29 2012-07-05 Deutsches Zentrum für Luft- und Raumfahrt e.V. Piezokeramischer Flächenaktuator und Verfahren zur Herstellung eines solchen
FR2908329B1 (fr) 2006-11-14 2011-01-07 Telemaq Dispositif et methode de distribution de fluide par ultrasons
US8196576B2 (en) * 2007-02-28 2012-06-12 Microdose Therapeutx, Inc. Inhaler
US20080214940A1 (en) 2007-03-02 2008-09-04 Benaron David A Medical imaging lens system, and method with high-efficiency light collection and collinear illumination
US20090008413A1 (en) 2007-04-17 2009-01-08 Choi Hee Jin Airless dispensing pump container with an airtight push down type nozzle head
ITRM20070275A1 (it) 2007-05-17 2008-11-18 Federighi Federigo Flacone erogatore multidose per preparati liquidi senza conservanti.
US8272576B2 (en) * 2007-06-22 2012-09-25 Arizona Board of Regents, a body corporate acting for and on behalf of Arizona State University Gas dynamic virtual nozzle for generation of microscopic droplet streams
JP5137710B2 (ja) * 2007-07-26 2013-02-06 キヤノン株式会社 液体カートリッジ
US8087303B2 (en) * 2007-09-06 2012-01-03 Deka Products Limited Partnership Product dispensing system
JP5668476B2 (ja) 2007-10-08 2015-02-12 オーリニア・ファーマシューティカルズ・インコーポレイテッドＡｕｒｉｎｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． カルシニューリン阻害剤またはｍＴＯＲ阻害剤を含む眼科用組成物
US20090114737A1 (en) 2007-11-07 2009-05-07 Health & Life Co., Ltd. Aerosolization device
US20090212127A1 (en) 2007-12-14 2009-08-27 Weidlinger Associates, Inc. Fuel injector with single crystal piezoelectric actuator stack
US20090212133A1 (en) 2008-01-25 2009-08-27 Collins Jr James F Ophthalmic fluid delivery device and method of operation
US8734408B2 (en) 2008-02-05 2014-05-27 Alvin J. Marx Automated eyedrop delivery system with eyelid retracting legs
AU2009232352B2 (en) 2008-04-04 2013-09-05 Mimetogen Pharmaceuticals Inc. Beta-turn peptidomimetic cyclic compounds for treating dry eye
WO2009139817A2 (en) 2008-04-15 2009-11-19 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
DE102008022987A1 (de) 2008-05-09 2009-11-12 Pari Pharma Gmbh Vernebler für Beatmungsmaschinen und Beatmungsmaschine mit einem solchen Vernebler
JP5385975B2 (ja) * 2008-05-23 2014-01-08 富士フイルム株式会社 流体液滴吐出
US20100001090A1 (en) 2008-07-03 2010-01-07 Arthur Hampton Neergaard Liquid Particle Emitting Device
US8944344B2 (en) * 2008-07-08 2015-02-03 Sonics & Materials Inc. Multi-element ultrasonic atomizer
US7656076B1 (en) 2008-07-15 2010-02-02 Iptrade, Inc. Unimorph/bimorph piezoelectric package
US20100072301A1 (en) 2008-09-19 2010-03-25 Miro Cater Discharge device
US20100076388A1 (en) 2008-09-19 2010-03-25 Miro Cater Discharge device for pharmaceutical media
US20100072302A1 (en) 2008-09-19 2010-03-25 Miro Cater Discharge device
US20090192443A1 (en) 2008-10-06 2009-07-30 Collins Jr James F Ophthalmic fluid delivery device and method of operation
JP5731980B2 (ja) 2008-10-09 2015-06-10 ラムズコア， インコーポレイテッド ドライアイ症候群の処置のための組成物および方法
WO2010078428A1 (en) 2008-12-30 2010-07-08 Optimyst Systems, Inc. Ophthalmic fluid delivery system
WO2010126626A2 (en) 2009-05-01 2010-11-04 Aerie Pharmaceuticals, Inc. Dual mechanism inhibitors for the treatment of disease
WO2011010310A1 (en) * 2009-07-22 2011-01-27 Advanced Ophthalmic Pharma Ltd. Device for applying an ophthalmic medicament mist
FR2950036B1 (fr) 2009-09-11 2011-12-16 Rexam Pharma La Verpilliere Dispositif de distribution de liquide
EP2302712A1 (en) 2009-09-28 2011-03-30 Stichting IMEC Nederland Method for resonance frequency tuning of micromachined structures
US8596781B2 (en) * 2009-10-15 2013-12-03 Adlens Beacon, Inc. Fluid filled lens reservoir system and manufacturing method of the reservoir system
US20110106025A1 (en) 2009-10-29 2011-05-05 Hall Gary S Ophthalmic fluid pump
US8378105B2 (en) 2009-10-21 2013-02-19 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
US9039666B2 (en) 2009-10-21 2015-05-26 Johnson & Johnson Vision Care, Inc. Method and apparatus for liquid dispensing
US9801757B2 (en) 2011-08-31 2017-10-31 Johnson & Johnson Vision Care, Inc. Liquid dispensing reservoir
CN102655946A (zh) 2009-11-18 2012-09-05 雷克特本克斯尔有限责任公司 超声波表面处理设备和方法
US10012665B2 (en) * 2010-02-09 2018-07-03 Microjet Corporation Discharge device for liquid material including particle-like bodies
DE102010011047A1 (de) 2010-03-11 2011-09-15 Johnson Matthey Catalysts (Germany) Gmbh Biegewandler
KR20130092959A (ko) 2010-04-06 2013-08-21 리실 인터내셔널 리미티드 파트너쉽 계량된 볼륨들의 순수 또는 무균성 유동가능 물질들을 분배하기 위한 전달 시스템
DE102010003810A1 (de) 2010-04-09 2011-10-13 Henkel Ag & Co. Kgaa Abgabevorrichtung mit piezo-elektrischem Element
US8792767B2 (en) 2010-04-16 2014-07-29 Ccs Technology, Inc. Distribution device
JP5171879B2 (ja) 2010-05-06 2013-03-27 株式会社エヌ・ティ・ティ・ドコモ 移動通信端末及び再接続方法
KR101153613B1 (ko) * 2010-05-25 2012-06-18 삼성전기주식회사 마이크로 이젝터 및 그 제조방법
DE102010017216A1 (de) 2010-06-02 2011-12-08 Technische Universität Berlin Ventilvorrichtung zum Steuern eines Flusses eines Fluides durch einen Fluidkanal, Anordnung sowie Mehrwegventilvorrichtung
WO2012009702A1 (en) 2010-07-15 2012-01-19 Corinthian Ophthalmic, Inc. Method and system for performing remote treatment and monitoring
AU2011278934B2 (en) 2010-07-15 2015-02-26 Eyenovia, Inc. Drop generating device
MX2013000604A (es) 2010-07-15 2013-07-05 Corinthian Ophthalmic Inc Suministro oftálmico de fármaco.
US10154923B2 (en) 2010-07-15 2018-12-18 Eyenovia, Inc. Drop generating device
US9132243B2 (en) 2010-07-23 2015-09-15 Tannermedico A/S Method of administering a substance to the throat
FR2963326B1 (fr) 2010-07-30 2012-09-07 Rexam Healthcare La Verpillier Embout et recipient de distribution de liquide
IE20110394A1 (en) * 2010-09-07 2013-01-02 Univ Limerick A liquid droplet dispenser
DK2665557T3 (da) * 2011-01-21 2020-04-06 Biodot Inc Piezoelektrisk dispenser med en langsgående transducer og udskifteligt kapillærrør
US20130206857A1 (en) 2011-01-21 2013-08-15 Biodot, Inc. Piezoelectric dispenser with a longitudinal transducer and replaceable capillary tube
US9186690B2 (en) 2011-02-01 2015-11-17 Bausch & Lomb Incorporated Ergonomic hand-operable fluid-dispensing device
WO2012106501A1 (en) * 2011-02-02 2012-08-09 The Charles Stark Draper Laboratory, Inc. Drug delivery apparatus
MX2014000419A (es) 2011-07-15 2014-09-22 Nusirt Sciences Inc Composicones y metodos para modular trayectorias metabolicas.
JP6357416B2 (ja) 2011-07-19 2018-07-11 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． アクチュエーターを有する家庭用電気器具
US9346075B2 (en) 2011-08-26 2016-05-24 Nordson Corporation Modular jetting devices
WO2013043607A1 (en) 2011-09-19 2013-03-28 Kraft Daniel L Eye drop dispenser
IN2014CN02961A (enExample) 2011-09-20 2015-07-03 Altavista Inst De Invest Medica S A S
DE102011114584B3 (de) 2011-09-30 2012-05-31 Carl Zeiss Meditec Ag Ophthalmochirurgische Steuerungsvorrichtung und ophthalmochirurgisches System mit einer solchen Steuerungsvorrichtung
US8957048B2 (en) 2011-10-06 2015-02-17 Allergan, Inc. Compositions for the treatment of dry eye
US20140285121A1 (en) 2011-11-08 2014-09-25 Fairchild Semiconductor Corporation Modulation scheme for driving a piezo element
KR101258025B1 (ko) 2011-11-21 2013-04-25 동아대학교 산학협력단 자동 안약 투여장치
DE102011086755A1 (de) 2011-11-21 2013-05-23 Aptar Radolfzell Gmbh Spender zum Austrag von pharmazeutischen Flüssigkeiten
CH705799A1 (it) 2011-11-24 2013-05-31 Luso Pharma Sagl Testa di erogazione multi-dose con otturatore a membrana elastica. originale: Testa di erogazione multi-dose perfezionata.
CN104487028A (zh) * 2011-12-12 2015-04-01 艾诺维亚股份有限公司 高模量聚合物喷射器机构、喷射器装置及其使用方法
US8591635B2 (en) 2011-12-19 2013-11-26 Chrysler Group Llc Fluid aeration-reduction system
US20130164436A1 (en) 2011-12-27 2013-06-27 Ricoh Company Thin film manufacturing apparatus, thin film manufacturing method, liquid droplet ejecting head, and inkjet recording apparatus
US9254642B2 (en) 2012-01-19 2016-02-09 AdvanJet Control method and apparatus for dispensing high-quality drops of high-viscosity material
AU2013245946A1 (en) 2012-04-10 2014-11-27 Eyenovia, Inc. Spray ejector mechanisms and devices providing charge isolation and controllable droplet charge, and low dosage volume opthalmic administration
AU2013249108A1 (en) 2012-04-20 2014-12-04 Eyenovia, Inc. Spray ejector device and methods of use
US9821125B2 (en) * 2012-04-26 2017-11-21 Koninklijke Philips N.V. Nebulizer and a method of manufacturing a nebulizer
SG11201407431RA (en) 2012-05-15 2014-12-30 Eyenovia Inc Ejector devices, methods, drivers, and circuits therefor
EP2664329A1 (de) 2012-05-15 2013-11-20 F. Holzer GmbH Ophthalmologisches Vehikelsystem
US9132238B2 (en) 2012-06-26 2015-09-15 Becton, Dickinson And Company Blow fill seal luer syringe
EP2877465A4 (en) 2012-07-25 2016-05-11 Sarcode Bioscience Inc LFA-1 HEMMER AND POLYMORPH THEREOF
JP6378681B2 (ja) 2012-09-07 2018-08-22 グラクソ グループ リミテッドＧｌａｘｏ Ｇｒｏｕｐ Ｌｉｍｉｔｅｄ 液滴ディスペンサ
EP2902047B1 (en) 2012-09-27 2018-04-18 Terumo Kabushiki Kaisha Infusion pump
US8927921B1 (en) 2012-10-02 2015-01-06 Sun Nuclear Corporation Systems and methods for composite dose quality assurance with three dimensional arrays
US9901117B2 (en) 2013-02-12 2018-02-27 Sis Resources, Ltd. Inductive charging for an electronic cigarette
US9962288B2 (en) 2013-03-07 2018-05-08 Novartis Ag Active acoustic streaming in hand piece for occlusion surge mitigation
US20140276054A1 (en) 2013-03-15 2014-09-18 Volcano Corporation Piezoelectric-Actuated Fluid-Delivery Devices and Associated Systems and Methods
US20150018781A1 (en) 2013-04-10 2015-01-15 California Institute Of Technology Systems, devices, and methods for topical drug delivery to the eye
US20150035180A1 (en) 2013-08-02 2015-02-05 Forward Optics Co., Ltd. Method for fabricating an arrayed optical element
US8976451B2 (en) 2013-08-02 2015-03-10 Forward Optics Co., Ltd Lens array module
WO2015031389A2 (en) 2013-08-26 2015-03-05 Lightside Md, Llc Adhesive support devices and methods of making and using them
US20150086397A1 (en) * 2013-09-25 2015-03-26 Hsiao-Kang Ma Micropump with separate chamber
US9282803B2 (en) 2013-10-03 2016-03-15 Donald John Ciervo Ultrasonic cosmetic applicator
US9676525B2 (en) 2013-12-17 2017-06-13 Aptar Radolfzell Gmbh Protective cap for a dispenser, and discharge device for discharging pharmaceutical and/or cosmetical liquids
WO2015106180A1 (en) * 2014-01-10 2015-07-16 Marcio Marc Abreu Devices to monitor and provide treatment at an abreu brain tunnel
US20150256730A1 (en) 2014-03-05 2015-09-10 Forward Optics Co., Ltd. Image-capturing device configured for a handheld electronic device
US20150276994A1 (en) 2014-03-28 2015-10-01 Forward Optics Co., Ltd. Method of making a lens array plate with an aperture mask layer
DE102014208064B4 (de) 2014-04-29 2015-12-03 Heraeus Medical Gmbh Lavage-System mit einem Druckgasmotor sowie Verfahren zum Erzeugen eines Sprühstoßes
US10307550B2 (en) 2014-06-09 2019-06-04 Dance Biopharm Inc. Liquid drug cartridges and associated dispenser
WO2016009870A1 (ja) 2014-07-16 2016-01-21 株式会社村田製作所 流体制御装置
CN104146816B (zh) * 2014-09-02 2016-04-13 镇江万新光学眼镜有限公司 一种眼部雾化送药装置
TWI658828B (zh) 2014-10-31 2019-05-11 中國醫藥大學 用於舒緩及減輕近視之醫藥組合物及其製備方法與用途
EP3244851B1 (en) 2015-01-12 2024-10-16 Bausch + Lomb Ireland Limited Micro-droplet delivery device
KR20170108057A (ko) 2015-01-23 2017-09-26 윌리엄 탄 초음파 증발 요소
KR20170135862A (ko) 2015-04-10 2017-12-08 켄달리온 테라퓨틱스 인코포레이티드 교체 가능한 앰플을 갖는 압전 디스펜서
GB201507687D0 (en) 2015-04-30 2015-06-17 Leafgreen Ltd Pulsed spray nozzle arrangement
US9700686B2 (en) 2015-06-03 2017-07-11 Novopyxis, Inc. Fluid delivery devices and methods
CN204813955U (zh) 2015-07-22 2015-12-02 吉林大学 可调压力腔室体积的次声实验系统
US20170028626A1 (en) 2015-07-29 2017-02-02 Ecole Polytechnique Federale De Lausanne (Epfl) Compact Drop-on-Demand Apparatus Using Light Actuation Through Optical Fibers
US20180229247A1 (en) 2015-08-14 2018-08-16 Leafgreen Limited Pulsed spray nozzle arrangements
GB201518337D0 (en) 2015-10-16 2015-12-02 The Technology Partnership Plc Linear device
DE102015224617B4 (de) * 2015-12-08 2017-07-20 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Freistrahldosiersystem für das Auge
CN105351426A (zh) 2015-12-14 2016-02-24 陈鸽 一种减振器及开关装置
JP2017120975A (ja) 2015-12-28 2017-07-06 ルネサスエレクトロニクス株式会社 撮像素子
WO2017161404A1 (en) 2016-03-24 2017-09-28 Brien Holden Vision Institute Devices and method for generating a stimulus to evaluate ocular sensitivity
US10672298B2 (en) 2016-10-17 2020-06-02 Sanmina Corporation System and method for a blood flow simulator
CN109906120A (zh) 2017-01-20 2019-06-18 科达莱昂治疗公司 压电流体分配器
KR102643190B1 (ko) 2017-06-10 2024-03-04 아이노비아 인코포레이티드 유체를 취급하기 위한, 그리고 눈에 유체를 전달하기 위한 디바이스들
CN109674576B (zh) 2017-10-19 2024-02-27 深圳市启明医药科技有限公司 流体供应单元及微液滴喷射驱动装置、发生装置
WO2019113483A1 (en) 2017-12-08 2019-06-13 Kedalion Therapeutics, Inc. Fluid delivery alignment system
WO2019200121A1 (en) 2018-04-12 2019-10-17 Kedalion Therapeutics, Inc. Topical ocular delivery methods and devices for use in the same
EP3817696B8 (en) 2018-07-03 2024-12-11 Bausch + Lomb Ireland Limited Topical ocular delivery devices
US11744965B2 (en) 2018-07-23 2023-09-05 The Bar Code Registry, Inc. System for analyzing and controlling consumable media dosing information
KR20210135269A (ko) 2019-03-04 2021-11-12 아이노비아 인코포레이티드 필로카르핀을 눈에 액적의 마이크로-용량 스트림으로 전달하기 위한 방법 및 장치
US12097145B2 (en) 2019-03-06 2024-09-24 Bausch + Lomb Ireland Limited Vented multi-dose ocular fluid delivery system
US11679028B2 (en) 2019-03-06 2023-06-20 Novartis Ag Multi-dose ocular fluid delivery system
CA3180199A1 (en) 2020-04-17 2021-10-21 Yehuda Ivri Hydrodynamically actuated preservative free dispensing system
US11938057B2 (en) 2020-04-17 2024-03-26 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system
US12290472B2 (en) 2020-04-17 2025-05-06 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system
EP4120973B1 (en) 2020-04-17 2026-06-10 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system having a collapsible liquid reservoir

Also Published As

Publication number Publication date
US12453651B2 (en) 2025-10-28
EP3244851A4 (en) 2018-08-22
CN107106325A (zh) 2017-08-29
JP2018510668A (ja) 2018-04-19
KR101984116B1 (ko) 2019-05-31
US11819453B2 (en) 2023-11-21
WO2016115050A1 (en) 2016-07-21
EP3244851B1 (en) 2024-10-16
CN107106325B (zh) 2021-05-25
EP3244851A1 (en) 2017-11-22
US10624781B2 (en) 2020-04-21
US20200246182A1 (en) 2020-08-06
CA2973471A1 (en) 2016-07-21
KR20170104555A (ko) 2017-09-15
US20160199225A1 (en) 2016-07-14
CN113230021A (zh) 2021-08-10
US20240156637A1 (en) 2024-05-16

Similar Documents

Publication Publication Date Title
US12453651B2 (en) Micro-droplet delivery device and methods
US12048647B2 (en) Piezoelectric dispenser with replaceable ampoule
US20200197220A1 (en) Ophthalmic Dispenser With Replaceable Ampoule
US10646373B2 (en) Ejector mechanism, ejector device, and methods of use

Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application