AU2014343379B2 - Methods and compositions for sustained immunotherapy - Google Patents

Methods and compositions for sustained immunotherapy Download PDF

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AU2014343379B2
AU2014343379B2 AU2014343379A AU2014343379A AU2014343379B2 AU 2014343379 B2 AU2014343379 B2 AU 2014343379B2 AU 2014343379 A AU2014343379 A AU 2014343379A AU 2014343379 A AU2014343379 A AU 2014343379A AU 2014343379 B2 AU2014343379 B2 AU 2014343379B2
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cells
pmhc
mhc
antigen
nanoparticle
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AU2014343379A1 (en
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Pedro Santamaria
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UTI LP
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    • AHUMAN NECESSITIES
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    • A61K39/0005Vertebrate antigens
    • A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/52Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an inorganic compound, e.g. an inorganic ion that is complexed with the active ingredient
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    • A61K47/6931Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle the material constituting the nanoparticle being a polymer
    • A61K47/6939Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle the material constituting the nanoparticle being a polymer the polymer being a polysaccharide, e.g. starch, chitosan, chitin, cellulose or pectin
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    • A61K9/513Organic macromolecular compounds; Dendrimers
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    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
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    • C12N2710/24011Poxviridae
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    • C12N2740/15041Use of virus, viral particle or viral elements as a vector
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AU2014343379A 2013-11-04 2014-11-03 Methods and compositions for sustained immunotherapy Active AU2014343379B2 (en)

Priority Applications (1)

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AU2019203154A AU2019203154A1 (en) 2013-11-04 2019-05-06 Methods and compositions for sustained immunotherapy

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US201361899826P 2013-11-04 2013-11-04
US61/899,826 2013-11-04
PCT/IB2014/003014 WO2015063616A2 (en) 2013-11-04 2014-11-03 Methods and compositions for sustained immunotherapy

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US (3) US10124045B2 (enExample)
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JP (2) JP2017500285A (enExample)
KR (1) KR20160077202A (enExample)
CN (1) CN105899229A (enExample)
AU (2) AU2014343379B2 (enExample)
CA (1) CA2929700C (enExample)
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US9511151B2 (en) 2010-11-12 2016-12-06 Uti Limited Partnership Compositions and methods for the prevention and treatment of cancer
US10988516B2 (en) 2012-03-26 2021-04-27 Uti Limited Partnership Methods and compositions for treating inflammation
US9603948B2 (en) 2012-10-11 2017-03-28 Uti Limited Partnership Methods and compositions for treating multiple sclerosis and related disorders
EP3013361B1 (en) 2013-06-24 2021-10-06 NexImmune, Inc. Compositions and methods for immunotherapy
AU2014343379B2 (en) 2013-11-04 2019-02-14 Uti Limited Partnership Methods and compositions for sustained immunotherapy
GB201418433D0 (en) 2014-10-17 2014-12-03 Imcyse Sa Novel immunogenic peptides
WO2016105542A2 (en) 2014-12-24 2016-06-30 Neximmune, Inc Nanoparticle compositions and methods for immunotherapy
EP3291832B1 (en) 2015-05-06 2025-09-03 UTI Limited Partnership Nanoparticle compositions for sustained therapy
US20170205404A1 (en) * 2016-01-19 2017-07-20 General Electric Company Multifunctional beads and methods of use for capturing rare cells
US20180127481A1 (en) * 2016-11-09 2018-05-10 Uti Limited Partnership RECOMBINANT pMHC CLASS II MOLECULES
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