AU2014332732B2 - Method of producing L-amino acids - Google Patents

Method of producing L-amino acids Download PDF

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Publication number
AU2014332732B2
AU2014332732B2 AU2014332732A AU2014332732A AU2014332732B2 AU 2014332732 B2 AU2014332732 B2 AU 2014332732B2 AU 2014332732 A AU2014332732 A AU 2014332732A AU 2014332732 A AU2014332732 A AU 2014332732A AU 2014332732 B2 AU2014332732 B2 AU 2014332732B2
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AU
Australia
Prior art keywords
gene
seq
acetate
lysine
amino acids
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AU2014332732A
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AU2014332732A1 (en
Inventor
Hyun Won BAE
Do Hyun Kwon
Kwang Ho Lee
Sang Jo Lim
Jun Ok Moon
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CJ CheilJedang Corp
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CJ CheilJedang Corp
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Priority claimed from PCT/KR2014/009468 external-priority patent/WO2015053552A1/en
Publication of AU2014332732A1 publication Critical patent/AU2014332732A1/en
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Priority to AU2017272295A priority Critical patent/AU2017272295B2/en
Publication of AU2014332732B2 publication Critical patent/AU2014332732B2/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y403/00—Carbon-nitrogen lyases (4.3)
    • C12Y403/03—Amine-lyases (4.3.3)
    • C12Y403/03007—4-Hydroxy-tetrahydrodipicolinate synthase (4.3.3.7)

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
AU2014332732A 2013-10-11 2014-10-08 Method of producing L-amino acids Active AU2014332732B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2017272295A AU2017272295B2 (en) 2013-10-11 2017-12-07 Method of Producing L-Amino Acids

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR10-2013-0121090 2013-10-11
KR20130121090 2013-10-11
KR1020140091307A KR101518860B1 (ko) 2013-10-11 2014-07-18 L-아미노산의 생산 방법
KR10-2014-0091307 2014-07-18
PCT/KR2014/009468 WO2015053552A1 (en) 2013-10-11 2014-10-08 Method of producing l-amino acids

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2017272295A Division AU2017272295B2 (en) 2013-10-11 2017-12-07 Method of Producing L-Amino Acids

Publications (2)

Publication Number Publication Date
AU2014332732A1 AU2014332732A1 (en) 2016-04-21
AU2014332732B2 true AU2014332732B2 (en) 2017-12-07

Family

ID=53035683

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2014332732A Active AU2014332732B2 (en) 2013-10-11 2014-10-08 Method of producing L-amino acids
AU2017272295A Active AU2017272295B2 (en) 2013-10-11 2017-12-07 Method of Producing L-Amino Acids

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2017272295A Active AU2017272295B2 (en) 2013-10-11 2017-12-07 Method of Producing L-Amino Acids

Country Status (16)

Country Link
JP (3) JP6291042B2 (pl)
KR (1) KR101518860B1 (pl)
CN (1) CN104561163B (pl)
AR (1) AR097977A1 (pl)
AU (2) AU2014332732B2 (pl)
BR (1) BR112016008029A2 (pl)
CA (1) CA2925659C (pl)
DK (1) DK2860256T3 (pl)
ES (1) ES2626048T3 (pl)
GE (1) GEP20196943B (pl)
JO (1) JO3255B1 (pl)
MY (1) MY172463A (pl)
PH (1) PH12016500640A1 (pl)
PL (1) PL2860256T3 (pl)
RU (2) RU2614258C2 (pl)
UA (1) UA117935C2 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101518860B1 (ko) * 2013-10-11 2015-05-12 씨제이제일제당 (주) L-아미노산의 생산 방법
CN105734004B (zh) * 2016-03-02 2020-06-19 廊坊梅花生物技术开发有限公司 重组菌株及其制备方法、应用
KR101925930B1 (ko) * 2017-07-24 2019-02-26 씨제이제일제당 주식회사 Ｌ-라이신을 생산하는 미생물 및 이를 이용한 ｌ-라이신의 생산 방법
AR114670A1 (es) 2018-03-09 2020-09-30 Cj Cheiljedang Corp Un promotor y un método para producir l-aminoácidos utilizando el mismo
KR102221040B1 (ko) * 2019-05-09 2021-03-03 씨제이제일제당 주식회사 L-아미노산을 생산하는 미생물 및 이를 이용한 l-아미노산을 생산하는 방법
KR102134418B1 (ko) * 2019-06-17 2020-07-16 씨제이제일제당 주식회사 L-타이로신을 생산하는 미생물 및 이를 이용한 l-타이로신 생산 방법
KR102207867B1 (ko) * 2020-01-21 2021-01-26 씨제이제일제당 주식회사 Nadp 의존적 글리세르알데하이드-3-포스페이트 디하이드로지나제를 포함하는 미생물을 이용하여 ｌ-아미노산을 생산하는 방법

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6649379B1 (en) * 1987-06-12 2003-11-18 Massachusetts Institute Of Technology Method and deregulated enzyme for threonine production
JP3036912B2 (ja) * 1991-09-02 2000-04-24 協和醗酵工業株式会社 遺伝子発現調節ｄｎａ
CN1117152C (zh) * 1994-03-04 2003-08-06 味之素株式会社 生产l－赖氨酸的方法
ZA964665B (en) * 1995-06-07 1997-01-07 Ajinomoto Kk Method of producing l-lysine
ATE263246T1 (de) * 1999-02-20 2004-04-15 Degussa Verfahren zur fermentativen herstellung von l- aminosäuren unter verwendung coryneformer bakterien
JP4306169B2 (ja) * 1999-12-24 2009-07-29 味の素株式会社 Ｌ−アミノ酸の製造法及び新規遺伝子
WO2002040679A2 (en) * 2000-11-15 2002-05-23 Archer-Daniels-Midland Company Corynebacterium glutamicum promoters
KR100397423B1 (ko) * 2001-02-13 2003-09-13 씨제이 주식회사 Ｌ-쓰레오닌의 제조방법
DE10224088A1 (de) * 2002-05-31 2003-12-11 Degussa Verfahren zur Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien die ein abgeschwächtes mez-Gen enthalten
JP2004261150A (ja) * 2003-03-04 2004-09-24 Ajinomoto Co Inc 目的物質の製造法
JP2005006564A (ja) 2003-06-19 2005-01-13 Japan Tobacco Inc 硝酸イオン誘導性プロモーター
JP2010226956A (ja) * 2007-07-23 2010-10-14 Ajinomoto Co Inc Ｌ−リジンの製造法
KR101335853B1 (ko) 2011-12-01 2013-12-02 씨제이제일제당 (주) Ｌ-아미노산 및 리보플라빈을 동시에 생산하는 미생물 및 이를 이용한 ｌ-아미노산 및 리보플라빈을 생산하는 방법
KR101518860B1 (ko) * 2013-10-11 2015-05-12 씨제이제일제당 (주) L-아미노산의 생산 방법

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BASTIAN BLOMBACH ET AL, "Effect of pyruvate dehydrogenase complex deficiency on l-lysine production with Corynebacterium glutamicum", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER, BERLIN, DE, (20070302), vol. 76, no. 3, pages 615 - 623 *

Also Published As

Publication number Publication date
ES2626048T3 (es) 2017-07-21
RU2015151124A (ru) 2016-06-27
AU2017272295B2 (en) 2019-05-16
JP2018113966A (ja) 2018-07-26
AU2014332732A1 (en) 2016-04-21
KR101518860B1 (ko) 2015-05-12
JP6291042B2 (ja) 2018-03-14
PL2860256T3 (pl) 2017-08-31
BR112016008029A2 (pt) 2017-10-03
PH12016500640B1 (en) 2016-05-30
DK2860256T3 (en) 2017-06-06
RU2614258C2 (ru) 2017-03-24
JP6824918B2 (ja) 2021-02-03
CA2925659C (en) 2018-10-23
MY172463A (en) 2019-11-26
RU2016110804A (ru) 2016-07-27
GEP20196943B (en) 2019-02-11
KR20150042692A (ko) 2015-04-21
RU2651461C2 (ru) 2018-04-19
JP2020078312A (ja) 2020-05-28
PH12016500640A1 (en) 2016-05-30
AR097977A1 (es) 2016-04-20
CN104561163A (zh) 2015-04-29
JO3255B1 (ar) 2018-09-16
JP2016532439A (ja) 2016-10-20
AU2017272295A1 (en) 2018-01-04
CA2925659A1 (en) 2015-04-16
CN104561163B (zh) 2018-11-06
UA117935C2 (uk) 2018-10-25

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