AU2014278183B2 - Novel GLP-1 receptor modulators - Google Patents

Novel GLP-1 receptor modulators Download PDF

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AU2014278183B2
AU2014278183B2 AU2014278183A AU2014278183A AU2014278183B2 AU 2014278183 B2 AU2014278183 B2 AU 2014278183B2 AU 2014278183 A AU2014278183 A AU 2014278183A AU 2014278183 A AU2014278183 A AU 2014278183A AU 2014278183 B2 AU2014278183 B2 AU 2014278183B2
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AU2014278183A1 (en
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Marcus F. Boehm
Enugurthi Brahmachary
Thomas Fowler
Liming Huang
Michael Knaggs
Esther Martinborough
Premji Meghani
Manisha Moorjani
Andrew Novak
Junko Tamiya
Adam R. Yeager
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Receptos LLC
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    • C07D495/04—Ortho-condensed systems
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    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
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    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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  • Chemical & Material Sciences (AREA)
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  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
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  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
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AU2014278183A 2013-06-11 2014-06-11 Novel GLP-1 receptor modulators Ceased AU2014278183B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361833737P 2013-06-11 2013-06-11
US61/833,737 2013-06-11
US201461981643P 2014-04-18 2014-04-18
US61/981,643 2014-04-18
PCT/US2014/041997 WO2014201172A1 (en) 2013-06-11 2014-06-11 Novel glp-1 receptor modulators

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