AU2014230834B9 - Injectable morphine formulations - Google Patents

Injectable morphine formulations Download PDF

Info

Publication number
AU2014230834B9
AU2014230834B9 AU2014230834A AU2014230834A AU2014230834B9 AU 2014230834 B9 AU2014230834 B9 AU 2014230834B9 AU 2014230834 A AU2014230834 A AU 2014230834A AU 2014230834 A AU2014230834 A AU 2014230834A AU 2014230834 B9 AU2014230834 B9 AU 2014230834B9
Authority
AU
Australia
Prior art keywords
formulation
morphine
acid
dihydrate
months
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2014230834A
Other languages
English (en)
Other versions
AU2014230834A1 (en
AU2014230834B2 (en
Inventor
Alain Cuine
Didier Hoarau
Pauline ROMAIN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fresenius Kabi Deutschland GmbH
Original Assignee
Fresenius Kabi Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Kabi Deutschland GmbH filed Critical Fresenius Kabi Deutschland GmbH
Publication of AU2014230834A1 publication Critical patent/AU2014230834A1/en
Assigned to FRESENIUS KABI DEUTSCHLAND GMBH reassignment FRESENIUS KABI DEUTSCHLAND GMBH Request for Assignment Assignors: BECTON DICKINSON FRANCE S.A.S.
Application granted granted Critical
Publication of AU2014230834B2 publication Critical patent/AU2014230834B2/en
Publication of AU2014230834B9 publication Critical patent/AU2014230834B9/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
AU2014230834A 2013-03-14 2014-03-12 Injectable morphine formulations Active AU2014230834B9 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361785218P 2013-03-14 2013-03-14
US61/785,218 2013-03-14
PCT/EP2014/054831 WO2014140095A1 (en) 2013-03-14 2014-03-12 Injectable morphine formulations

Publications (3)

Publication Number Publication Date
AU2014230834A1 AU2014230834A1 (en) 2015-09-10
AU2014230834B2 AU2014230834B2 (en) 2017-08-03
AU2014230834B9 true AU2014230834B9 (en) 2017-08-31

Family

ID=50288050

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2014230834A Active AU2014230834B9 (en) 2013-03-14 2014-03-12 Injectable morphine formulations

Country Status (8)

Country Link
US (7) US9072781B2 (enExample)
EP (2) EP2968132B1 (enExample)
JP (1) JP6215970B2 (enExample)
CN (2) CN109125254A (enExample)
AU (1) AU2014230834B9 (enExample)
BR (1) BR112015021586B1 (enExample)
CA (1) CA2902343C (enExample)
WO (1) WO2014140095A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014140095A1 (en) 2013-03-14 2014-09-18 Becton Dickinson France S.A.S. Injectable morphine formulations
PT2968729T (pt) 2013-03-14 2018-11-06 Fresenius Kabi Deutschland Gmbh Sistema de acondicionamento para fármacos sensíveis ao oxigénio
CA2968915A1 (en) * 2014-12-03 2016-06-09 Csl Behring Ag Pharmaceutical product with increased stability comprising immunoglobulins
US20170189352A1 (en) 2015-03-13 2017-07-06 Par Pharmaceutical, Inc. Epinephrine formulations
US9119876B1 (en) 2015-03-13 2015-09-01 Par Pharmaceutical, Inc. Epinephrine formulations
US11369700B2 (en) 2015-05-25 2022-06-28 IGL Pharma Inc. DOTMP kit formulations for radioisotopes
JP6930922B2 (ja) * 2015-05-25 2021-09-01 アイジーエル ファーマ，インコーポレイティド 放射性同位体用ｄｏｔｍｐキット製剤
US20180064703A1 (en) 2016-09-02 2018-03-08 Sun Pharmaceutical Industries Ltd. Stable infusion dosage form of morphine
ES3027562T3 (en) * 2016-09-23 2025-06-16 Gruenenthal Gmbh Stable formulation for parenteral administration of tapentadol
CA3093725C (en) 2018-03-23 2021-08-24 Nevakar Inc. Epinephrine compositions and containers
CN114207101B (zh) 2019-07-31 2024-05-31 埃科莱布美国股份有限公司 免用个人防护设备的脱灰剂组合物
US11806320B2 (en) * 2020-02-19 2023-11-07 Endo Ventures Limited Isoproterenol compositions and methods
EP4265253A4 (en) * 2020-12-18 2024-11-27 FUJIFILM Toyama Chemical Co., Ltd. PHARMACEUTICAL COMPOSITION

Family Cites Families (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1048712A (en) 1912-02-23 1912-12-31 John Uri Lloyd Process of extracting, purifying, or excluding alkaloids and alkaloidal salts.
US2715627A (en) 1952-05-26 1955-08-16 Charles L Mehltretter Solvent extraction of opium alkaloids
US4071620A (en) 1977-01-10 1978-01-31 American Home Products Corporation Stabilization of oxygen sensitive dose forms
JPS56125876U (enExample) 1980-02-23 1981-09-25
US4367738A (en) 1981-10-28 1983-01-11 Janssen Pharmaceutica Inc. Pre-filled syringe for abusable drugs
EP0106290B1 (en) 1982-10-08 1988-04-06 TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION Evacuated blood collecting device
US4998400A (en) 1986-03-22 1991-03-12 Material Engineering Technology Laboratory, Incorporated Medical fluid-filled plastic container and methods of making same
JPS6311160A (ja) 1986-07-02 1988-01-18 株式会社新素材総合研究所 薬液容器収納体及びその製造方法
US5723147A (en) 1987-02-23 1998-03-03 Depotech Corporation Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride
US5807572A (en) 1988-02-18 1998-09-15 Depotech Corporation Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride
US5030216A (en) 1989-12-15 1991-07-09 Alza Corporation Osmotically driven syringe
JP3630436B2 (ja) 1991-11-13 2005-03-16 株式会社創研 米からの活性酸素消去剤
GB9200219D0 (en) 1992-01-07 1992-02-26 Medimech Int Ltd Automatic injectors
EP0673261A4 (en) 1992-12-14 1997-11-26 Mallinckrodt Medical Inc PROCESSES FOR PRODUCING PRE-FILLED LIQUID DELIVERY DEVICES WITHOUT EXTERNAL OR INTERNAL CONTAMINATION.
CA2120197A1 (en) * 1993-04-02 1994-10-03 Kenji Endo Stable aqueous dispersions containing liposomes
US5414049A (en) 1993-06-01 1995-05-09 Howmedica Inc. Non-oxidizing polymeric medical implant
SE9401986D0 (sv) 1994-06-08 1994-06-08 Pharmacia Ab New process for sterilization and articles sterilized thereby
US5624402A (en) 1994-12-12 1997-04-29 Becton, Dickinson And Company Syringe tip cap
US6196998B1 (en) 1994-12-12 2001-03-06 Becton Dickinson And Company Syringe and tip cap assembly
US5931809A (en) 1995-07-14 1999-08-03 Depotech Corporation Epidural administration of therapeutic compounds with sustained rate of release
US6054584A (en) 1996-11-19 2000-04-25 The Board Of Regents Of The University And Community College System Of Neveda Process for extracting and purifying morphine from opium
SE9601348D0 (sv) 1996-04-10 1996-04-10 Pharmacia Ab Improved containers for parenteral fluids
KR100304846B1 (ko) 1996-06-17 2001-09-24 오쓰카 요시미쓰 중탄산염 함유 약액 용기 포장체 및 피에이치인디케이터ㅔ
CA2258965A1 (en) 1996-06-28 1998-01-08 Oxigene, Inc. Useful formulations of acid addition salt drugs
US5997899A (en) 1996-10-01 1999-12-07 Skyepharma Inc. Method for producing liposomes with increased percent of compound encapsulated
JPH10182687A (ja) 1996-10-21 1998-07-07 Bayer Yakuhin Kk アカルボースの貯蔵安定化法
DE69729663T2 (de) 1996-12-16 2005-07-07 The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Kanüle mit stumpfen ende und zugangszapfen
US5891467A (en) 1997-01-31 1999-04-06 Depotech Corporation Method for utilizing neutral lipids to modify in vivo release from multivesicular liposomes
WO1998045191A1 (en) 1997-04-10 1998-10-15 Johns Hopkins University Gaz syringe and package therefor
JPH1147274A (ja) 1997-06-03 1999-02-23 Takeda Chem Ind Ltd ２室型注射器及び２室型注射器用接続具
WO1999022691A1 (en) 1997-10-31 1999-05-14 Abbott Laboratories System for storing oxygen sensitive compositions
US6200627B1 (en) 1998-03-17 2001-03-13 Becton, Dickinson And Company Low silicone glass prefillable syringe
US6361524B1 (en) 1998-04-14 2002-03-26 Becton, Dickinson And Company Syringe assembly
US6217550B1 (en) 1998-07-29 2001-04-17 Becton, Dickinson And Company Single-use syringe
US6333087B1 (en) 1998-08-27 2001-12-25 Chevron Chemical Company Llc Oxygen scavenging packaging
AU6046900A (en) * 1999-06-16 2001-01-02 Nastech Pharmaceutical Company, Inc Method for increasing the solubility of morphine and pharmaceutical compositionsprepared therefrom
US7137968B1 (en) 2000-03-13 2006-11-21 Nucryst Pharmaceuticals Corp. Transcutaneous medical device dressings and method of use
US6875400B2 (en) 2000-12-22 2005-04-05 Cryovac, Inc. Method of sterilizing and initiating a scavenging reaction in an article
JP2002253641A (ja) 2001-03-01 2002-09-10 Terumo Corp プレフィルドシリンジ用注射器包装体
EP1243524A3 (en) 2001-03-16 2004-04-07 Pfizer Products Inc. Pharmaceutical kit for oxygen-sensitive drugs
EP1241110A1 (en) 2001-03-16 2002-09-18 Pfizer Products Inc. Dispensing unit for oxygen-sensitive drugs
JP2003052819A (ja) 2001-08-10 2003-02-25 Seikagaku Kogyo Co Ltd 薬剤充填注射器包装物およびその滅菌または殺菌方法
CN1607968A (zh) 2001-11-02 2005-04-20 梅里迪安医学技术公司 药物容器、用于施用药物的药物配送套件及其包装方法
US6870273B2 (en) 2002-04-29 2005-03-22 Pmc-Sierra, Inc. High speed I/O pad and pad/cell interconnection for flip chips
JP2004057321A (ja) 2002-07-26 2004-02-26 Shionogi & Co Ltd 収着酸素が除去されたプラスチック容器
US20060010651A1 (en) 2002-10-08 2006-01-19 Hiroshi Honda Lifting device forming structure and chemical container having the structure
US20040102476A1 (en) 2002-11-25 2004-05-27 Chan Tai Wah High concentration formulations of opioids and opioid derivatives
EP1581285B1 (en) 2002-12-23 2009-02-25 Medtronic, Inc. Drug solution density adjustment systems and methods
EP1589902A1 (en) 2003-01-27 2005-11-02 Medtronic Vascular Connaught Improved packaging for stent delivery systems
JP2004229750A (ja) 2003-01-28 2004-08-19 Nipro Corp プレフィルドシリンジ及びそのバレルの製造方法
JP2006513938A (ja) 2003-03-25 2006-04-27 メドトロニック ヴァスキュラー コノート ステント及びステント運搬システムの包装
BRPI0409133B8 (pt) 2003-04-08 2021-05-25 Progenics Pharm Inc preparações farmacêuticas estavéis compreendendo metilnaltrexona
WO2004093775A1 (ja) 2003-04-23 2004-11-04 Otsuka Pharmaceutical Factory, Inc. 薬液充填プラスチックアンプルおよびその製造方法
US20040243214A1 (en) 2003-04-23 2004-12-02 Medtronic Vascular, Inc. Coated stent with protective packaging and method of using same
FR2855413B1 (fr) 2003-05-26 2005-12-30 Becton Dickinson France Seringue pre-remplie avec coiffe anti effraction
EP1653930B1 (en) 2003-08-05 2007-12-19 Zentiva, a.s. Methods for the stabilization of atorvastatin
US20050085785A1 (en) 2003-10-17 2005-04-21 Sherwin Shang High impact strength film and non-pvc containing container and pouch and overpouch
US20050228336A1 (en) 2004-04-07 2005-10-13 Preston Keusch Electrically assisted lidocaine and epinephrine delivery device having extended shelf-stability
JP4759232B2 (ja) 2004-07-02 2011-08-31 テルモ株式会社 包装されたプレフィルドシリンジの製造方法
CA2574102A1 (en) 2004-07-16 2006-01-26 Pfizer Products Inc. Pharmaceutical package for simultaneously maintaining low moisture and low oxygen levels
ATE422852T1 (de) 2004-12-08 2009-03-15 Perfecseal Inc Sterilisierbares paket mit hoher sauerstoffbarriere
KR101231965B1 (ko) 2005-04-28 2013-02-08 가부시키가이샤 오츠까 세이야꾸 고죠 약액 용기 수용체 및 그 제조 방법
WO2007023736A1 (ja) 2005-08-22 2007-03-01 Nipro Corporation プレフィルドシリンジ
BRPI0503734A (pt) 2005-08-23 2007-04-27 Cristalia Prod Quimicos Farm composição farmacêutica na forma de solução injetável de morfina pronta para uso e forma de dosagem unitária de morfina para administração epidural ou intratecal
TWI489984B (zh) 2006-08-04 2015-07-01 Wyeth Corp 用於非經腸道傳輸化合物之配方及其用途
JP2008067989A (ja) 2006-09-15 2008-03-27 Terumo Corp プレフィルドシリンジ用収納容器および包装されたプレフィルドシリンジ
GB0619060D0 (en) 2006-09-27 2006-11-08 Glaxosmithkline Biolog Sa Novel process
WO2008050837A1 (fr) 2006-10-27 2008-05-02 Otsuka Pharmaceutical Factory, Inc. Solution médicamenteuse ayant une teneur réduite en oxygène dissous, procédé de production de cette solution et unité contant la solution médicamenteuse ayant une teneur réduite en oxygène dissous
JP5411422B2 (ja) 2007-01-31 2014-02-12 関西電力株式会社 バイポーラ型半導体装置、その製造方法およびツェナー電圧の制御方法
US20080308444A1 (en) 2007-06-13 2008-12-18 Baxter International Inc. Packaging system and method of alerting a practitioner
US8002737B2 (en) 2007-10-04 2011-08-23 Hyprotek, Inc. Mixing/administration syringe devices, protective packaging and methods of protecting syringe handlers
JP5438896B2 (ja) 2007-12-27 2014-03-12 大日本印刷株式会社 プレフィルドシリンジ用の包装袋
US8623401B2 (en) * 2008-03-27 2014-01-07 Fenwafe Inc. Wafer formulation
FR2931681B1 (fr) 2008-05-30 2011-11-25 Becton Dickinson France Seringue a embout universel
US9095324B2 (en) 2008-06-20 2015-08-04 Boston Scientific Scimed, Inc. Package assembly
JP5587597B2 (ja) 2008-12-19 2014-09-10 藤森工業株式会社 包装体
JP5332958B2 (ja) 2009-06-29 2013-11-06 大日本印刷株式会社 プレフィルドシリンジ包装体及びプレフィルドシリンジ用パック
GB2471726B (en) 2009-07-10 2013-09-11 Oval Medical Technologies Ltd A pre-filled syringe including an oxygen absorber
NZ596668A (en) 2009-07-22 2013-09-27 Gruenenthal Chemie Oxidation-stabilized tamper-resistant dosage form
US9333288B2 (en) 2011-09-30 2016-05-10 Becton Dickinson France, S.A.S. Attachable plunger rod and associated packaging
WO2014140095A1 (en) * 2013-03-14 2014-09-18 Becton Dickinson France S.A.S. Injectable morphine formulations
PT2968729T (pt) 2013-03-14 2018-11-06 Fresenius Kabi Deutschland Gmbh Sistema de acondicionamento para fármacos sensíveis ao oxigénio

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"Morphin Merck Tropfen", Bundesverband der Pharmazeutischen Industrie, Rote Liste 2002, Frankfurt/Main, Rote Liste Service GmbH, (2002), page 05015 *

Also Published As

Publication number Publication date
CA2902343A1 (en) 2014-09-18
JP6215970B2 (ja) 2017-10-18
JP2016512210A (ja) 2016-04-25
US10213424B2 (en) 2019-02-26
EP2968132B1 (en) 2017-09-13
US20250228846A1 (en) 2025-07-17
AU2014230834A1 (en) 2015-09-10
AU2014230834B2 (en) 2017-08-03
EP3143988A1 (en) 2017-03-22
US20200345720A1 (en) 2020-11-05
EP2968132A1 (en) 2016-01-20
CN109125254A (zh) 2019-01-04
WO2014140095A1 (en) 2014-09-18
BR112015021586A2 (pt) 2017-07-18
CA2902343C (en) 2022-08-02
US9192608B2 (en) 2015-11-24
US20160175297A1 (en) 2016-06-23
US20140275144A1 (en) 2014-09-18
CN104042565A (zh) 2014-09-17
US20230414604A1 (en) 2023-12-28
US9072781B2 (en) 2015-07-07
BR112015021586B1 (pt) 2023-01-31
US20190167665A1 (en) 2019-06-06
US20150246036A1 (en) 2015-09-03

Similar Documents

Publication Publication Date Title
US20250228846A1 (en) Morphine formulations
RU2539387C2 (ru) Составы для парентеральной доставки соединений и их применение
US20080064743A1 (en) Dry powder compound formulations and uses thereof
JP2024506861A (ja) 物質使用障害の治療のための隔離化合物及びその使用
HK1233500A1 (en) Injectable morphine formulations
RU2483731C1 (ru) Раствор для инъекций, содержащий налбуфин
US20250195412A1 (en) Pharmaceutical formulations of r-ketamine
AU2013263750B2 (en) Formulations for parenteral delivery of compounds and uses thereof
HK1095737A1 (en) Medicinal composition in solution form

Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: FRESENIUS KABI DEUTSCHLAND GMBH

Free format text: FORMER APPLICANT(S): BECTON DICKINSON FRANCE S.A.S.

SREP Specification republished
FGA Letters patent sealed or granted (standard patent)