CN104042565A - 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途 - Google Patents
吗啡调配物、包含所述吗啡调配物的试剂盒和其用途 Download PDFInfo
- Publication number
- CN104042565A CN104042565A CN201410097764.7A CN201410097764A CN104042565A CN 104042565 A CN104042565 A CN 104042565A CN 201410097764 A CN201410097764 A CN 201410097764A CN 104042565 A CN104042565 A CN 104042565A
- Authority
- CN
- China
- Prior art keywords
- formulation
- morphine
- buffer
- months
- dihydrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811072429.6A CN109125254A (zh) | 2013-03-14 | 2014-03-14 | 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361785218P | 2013-03-14 | 2013-03-14 | |
| US61/785,218 | 2013-03-14 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811072429.6A Division CN109125254A (zh) | 2013-03-14 | 2014-03-14 | 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104042565A true CN104042565A (zh) | 2014-09-17 |
Family
ID=50288050
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811072429.6A Pending CN109125254A (zh) | 2013-03-14 | 2014-03-14 | 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途 |
| CN201410097764.7A Pending CN104042565A (zh) | 2013-03-14 | 2014-03-14 | 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811072429.6A Pending CN109125254A (zh) | 2013-03-14 | 2014-03-14 | 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途 |
Country Status (8)
| Country | Link |
|---|---|
| US (7) | US9072781B2 (enExample) |
| EP (2) | EP3143988A1 (enExample) |
| JP (1) | JP6215970B2 (enExample) |
| CN (2) | CN109125254A (enExample) |
| AU (1) | AU2014230834B9 (enExample) |
| BR (1) | BR112015021586B1 (enExample) |
| CA (1) | CA2902343C (enExample) |
| WO (1) | WO2014140095A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2695158T3 (es) | 2013-03-14 | 2019-01-02 | Fresenius Kabi Deutschland Gmbh | Sistema de envasado para fármacos sensibles al oxígeno |
| US9072781B2 (en) | 2013-03-14 | 2015-07-07 | Becton, Dickinson France S.A.S. | Morphine formulations |
| US12144861B2 (en) * | 2014-12-03 | 2024-11-19 | Csl Behring Ag | Pharmaceutical product with increased stability comprising immunoglobulins |
| US20170189352A1 (en) | 2015-03-13 | 2017-07-06 | Par Pharmaceutical, Inc. | Epinephrine formulations |
| US9119876B1 (en) | 2015-03-13 | 2015-09-01 | Par Pharmaceutical, Inc. | Epinephrine formulations |
| US11369700B2 (en) | 2015-05-25 | 2022-06-28 | IGL Pharma Inc. | DOTMP kit formulations for radioisotopes |
| WO2016191413A1 (en) * | 2015-05-25 | 2016-12-01 | Iso Therapeutics Group, Llc | Dotmp kit formulations for radioisotopes |
| EP3290025B1 (en) | 2016-09-02 | 2020-02-12 | Sun Pharmaceutical Industries Ltd | Stable infusion dosage form of morphine |
| EP3515412B1 (en) * | 2016-09-23 | 2025-04-23 | Grünenthal GmbH | Stable formulation for parenteral administration of tapentadol |
| WO2019183416A1 (en) | 2018-03-23 | 2019-09-26 | Nevakar Inc. | Epinephrine compositions and containers |
| WO2021022045A1 (en) | 2019-07-31 | 2021-02-04 | Ecolab Usa Inc. | Personal protective equipment free delimer compositions |
| US11806320B2 (en) * | 2020-02-19 | 2023-11-07 | Endo Ventures Limited | Isoproterenol compositions and methods |
| WO2022131117A1 (ja) * | 2020-12-18 | 2022-06-23 | 富士フイルム富山化学株式会社 | 医薬組成物 |
Citations (2)
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| CN1767831A (zh) * | 2003-04-08 | 2006-05-03 | 普罗热尼奇制药公司 | 包含甲基纳曲酮的药物配方 |
| WO2007022609A1 (en) * | 2005-08-23 | 2007-03-01 | Cristália Produtos Químicos Farmacêuticos Ltda. | Pharmaceutical composition of morphine in ready-to-use injectable solution form and single dosage form of morphine for epidural or intrathecal administration |
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-
2014
- 2014-03-12 US US14/207,245 patent/US9072781B2/en active Active
- 2014-03-12 EP EP16188526.4A patent/EP3143988A1/en not_active Withdrawn
- 2014-03-12 WO PCT/EP2014/054831 patent/WO2014140095A1/en not_active Ceased
- 2014-03-12 EP EP14710529.0A patent/EP2968132B1/en not_active Not-in-force
- 2014-03-12 AU AU2014230834A patent/AU2014230834B9/en active Active
- 2014-03-12 BR BR112015021586-6A patent/BR112015021586B1/pt active IP Right Grant
- 2014-03-12 JP JP2015562121A patent/JP6215970B2/ja active Active
- 2014-03-12 CA CA2902343A patent/CA2902343C/en active Active
- 2014-03-14 CN CN201811072429.6A patent/CN109125254A/zh active Pending
- 2014-03-14 CN CN201410097764.7A patent/CN104042565A/zh active Pending
-
2015
- 2015-05-18 US US14/715,277 patent/US9192608B2/en active Active
- 2015-10-20 US US14/887,803 patent/US10213424B2/en active Active
-
2019
- 2019-02-11 US US16/272,108 patent/US20190167665A1/en not_active Abandoned
-
2020
- 2020-03-18 US US16/823,073 patent/US20200345720A1/en not_active Abandoned
-
2023
- 2023-04-28 US US18/309,069 patent/US20230414604A1/en not_active Abandoned
-
2024
- 2024-10-28 US US18/928,917 patent/US20250228846A1/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1767831A (zh) * | 2003-04-08 | 2006-05-03 | 普罗热尼奇制药公司 | 包含甲基纳曲酮的药物配方 |
| WO2007022609A1 (en) * | 2005-08-23 | 2007-03-01 | Cristália Produtos Químicos Farmacêuticos Ltda. | Pharmaceutical composition of morphine in ready-to-use injectable solution form and single dosage form of morphine for epidural or intrathecal administration |
Non-Patent Citations (2)
| Title |
|---|
| 注射剂的溶剂与附加剂;潘卫三等;《工业药剂学》;20100630;第215页 * |
| 潘卫三等: "《工业药剂学》", 30 June 2010 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20250228846A1 (en) | 2025-07-17 |
| JP2016512210A (ja) | 2016-04-25 |
| CA2902343C (en) | 2022-08-02 |
| US20190167665A1 (en) | 2019-06-06 |
| US9192608B2 (en) | 2015-11-24 |
| CN109125254A (zh) | 2019-01-04 |
| AU2014230834B2 (en) | 2017-08-03 |
| US20230414604A1 (en) | 2023-12-28 |
| US20150246036A1 (en) | 2015-09-03 |
| EP2968132B1 (en) | 2017-09-13 |
| EP3143988A1 (en) | 2017-03-22 |
| EP2968132A1 (en) | 2016-01-20 |
| US20160175297A1 (en) | 2016-06-23 |
| US20200345720A1 (en) | 2020-11-05 |
| US20140275144A1 (en) | 2014-09-18 |
| BR112015021586B1 (pt) | 2023-01-31 |
| BR112015021586A2 (pt) | 2017-07-18 |
| US10213424B2 (en) | 2019-02-26 |
| US9072781B2 (en) | 2015-07-07 |
| CA2902343A1 (en) | 2014-09-18 |
| WO2014140095A1 (en) | 2014-09-18 |
| AU2014230834A1 (en) | 2015-09-10 |
| JP6215970B2 (ja) | 2017-10-18 |
| AU2014230834B9 (en) | 2017-08-31 |
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