CN104042565A - 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途 - Google Patents

吗啡调配物、包含所述吗啡调配物的试剂盒和其用途 Download PDF

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Publication number
CN104042565A
CN104042565A CN201410097764.7A CN201410097764A CN104042565A CN 104042565 A CN104042565 A CN 104042565A CN 201410097764 A CN201410097764 A CN 201410097764A CN 104042565 A CN104042565 A CN 104042565A
Authority
CN
China
Prior art keywords
formulation
morphine
buffer
months
dihydrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410097764.7A
Other languages
English (en)
Chinese (zh)
Inventor
阿莱纳·屈内
迪迪埃·瓦罗
波利娜·罗曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fresenius Kabi Deutschland GmbH
Original Assignee
Becton Dickinson France SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson France SA filed Critical Becton Dickinson France SA
Priority to CN201811072429.6A priority Critical patent/CN109125254A/zh
Publication of CN104042565A publication Critical patent/CN104042565A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CN201410097764.7A 2013-03-14 2014-03-14 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途 Pending CN104042565A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811072429.6A CN109125254A (zh) 2013-03-14 2014-03-14 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361785218P 2013-03-14 2013-03-14
US61/785,218 2013-03-14

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201811072429.6A Division CN109125254A (zh) 2013-03-14 2014-03-14 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途

Publications (1)

Publication Number Publication Date
CN104042565A true CN104042565A (zh) 2014-09-17

Family

ID=50288050

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201811072429.6A Pending CN109125254A (zh) 2013-03-14 2014-03-14 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途
CN201410097764.7A Pending CN104042565A (zh) 2013-03-14 2014-03-14 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN201811072429.6A Pending CN109125254A (zh) 2013-03-14 2014-03-14 吗啡调配物、包含所述吗啡调配物的试剂盒和其用途

Country Status (8)

Country Link
US (7) US9072781B2 (enExample)
EP (2) EP3143988A1 (enExample)
JP (1) JP6215970B2 (enExample)
CN (2) CN109125254A (enExample)
AU (1) AU2014230834B9 (enExample)
BR (1) BR112015021586B1 (enExample)
CA (1) CA2902343C (enExample)
WO (1) WO2014140095A1 (enExample)

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US9072781B2 (en) 2013-03-14 2015-07-07 Becton, Dickinson France S.A.S. Morphine formulations
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US20170189352A1 (en) 2015-03-13 2017-07-06 Par Pharmaceutical, Inc. Epinephrine formulations
US9119876B1 (en) 2015-03-13 2015-09-01 Par Pharmaceutical, Inc. Epinephrine formulations
US11369700B2 (en) 2015-05-25 2022-06-28 IGL Pharma Inc. DOTMP kit formulations for radioisotopes
WO2016191413A1 (en) * 2015-05-25 2016-12-01 Iso Therapeutics Group, Llc Dotmp kit formulations for radioisotopes
EP3290025B1 (en) 2016-09-02 2020-02-12 Sun Pharmaceutical Industries Ltd Stable infusion dosage form of morphine
EP3515412B1 (en) * 2016-09-23 2025-04-23 Grünenthal GmbH Stable formulation for parenteral administration of tapentadol
WO2019183416A1 (en) 2018-03-23 2019-09-26 Nevakar Inc. Epinephrine compositions and containers
WO2021022045A1 (en) 2019-07-31 2021-02-04 Ecolab Usa Inc. Personal protective equipment free delimer compositions
US11806320B2 (en) * 2020-02-19 2023-11-07 Endo Ventures Limited Isoproterenol compositions and methods
WO2022131117A1 (ja) * 2020-12-18 2022-06-23 富士フイルム富山化学株式会社 医薬組成物

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Also Published As

Publication number Publication date
US20250228846A1 (en) 2025-07-17
JP2016512210A (ja) 2016-04-25
CA2902343C (en) 2022-08-02
US20190167665A1 (en) 2019-06-06
US9192608B2 (en) 2015-11-24
CN109125254A (zh) 2019-01-04
AU2014230834B2 (en) 2017-08-03
US20230414604A1 (en) 2023-12-28
US20150246036A1 (en) 2015-09-03
EP2968132B1 (en) 2017-09-13
EP3143988A1 (en) 2017-03-22
EP2968132A1 (en) 2016-01-20
US20160175297A1 (en) 2016-06-23
US20200345720A1 (en) 2020-11-05
US20140275144A1 (en) 2014-09-18
BR112015021586B1 (pt) 2023-01-31
BR112015021586A2 (pt) 2017-07-18
US10213424B2 (en) 2019-02-26
US9072781B2 (en) 2015-07-07
CA2902343A1 (en) 2014-09-18
WO2014140095A1 (en) 2014-09-18
AU2014230834A1 (en) 2015-09-10
JP6215970B2 (ja) 2017-10-18
AU2014230834B9 (en) 2017-08-31

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TA01 Transfer of patent application right

Effective date of registration: 20170113

Address after: German Homburg

Applicant after: Fresenius Kabi de GmbH

Address before: France Lepont de Clay

Applicant before: Bake Dun Dijinsen French company

RJ01 Rejection of invention patent application after publication

Application publication date: 20140917

RJ01 Rejection of invention patent application after publication