AU2014223243B2 - Talen-based gene correction - Google Patents
Talen-based gene correction Download PDFInfo
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- AU2014223243B2 AU2014223243B2 AU2014223243A AU2014223243A AU2014223243B2 AU 2014223243 B2 AU2014223243 B2 AU 2014223243B2 AU 2014223243 A AU2014223243 A AU 2014223243A AU 2014223243 A AU2014223243 A AU 2014223243A AU 2014223243 B2 AU2014223243 B2 AU 2014223243B2
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| US9850497B2 (en) * | 2013-11-04 | 2017-12-26 | Regents Of The University Of Minnesota | Gene targeting methods and tools |
| RU2714404C2 (ru) * | 2014-01-31 | 2020-02-14 | Фэктор Байосайенс Инк. | Способы и продукты для получения и доставки нуклеиновых кислот |
| DK3220926T3 (da) | 2014-11-17 | 2025-03-24 | Adicet Therapeutics Inc | Konstruerede gamma-delta-t-celler |
| CA2976376A1 (en) | 2015-02-13 | 2016-08-18 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| CN104726495B (zh) * | 2015-03-25 | 2018-06-19 | 西北农林科技大学 | 一种基于talen介导的基因打靶敲除山羊blg的载体及重组细胞 |
| EP4600366A3 (en) | 2015-03-31 | 2025-10-22 | SOHM, Inc. | Cas 9 retroviral integrase systems for targeted incorporation of a dna sequence into a genome of a cell |
| WO2016178207A1 (en) | 2015-05-04 | 2016-11-10 | Ramot At Tel-Aviv University Ltd. | Methods and kits for fragmenting dna |
| EP3466967A1 (en) | 2015-05-18 | 2019-04-10 | TCR2 Therapeutics Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
| WO2017023803A1 (en) | 2015-07-31 | 2017-02-09 | Regents Of The University Of Minnesota | Modified cells and methods of therapy |
| US20180296600A1 (en) * | 2015-10-27 | 2018-10-18 | The Board Of Trustees Of The Leland Stanford Junior University | Treatment of epidermolysis bullosa by injection of autologous collagen vii overexpressing leukocytes |
| PL3377637T3 (pl) * | 2016-04-08 | 2020-09-07 | Krystal Biotech, Inc. | Kompozycje do stosowania w sposobach leczenia ran, zaburzeń i chorób skóry |
| WO2017197347A1 (en) | 2016-05-12 | 2017-11-16 | Adicet Bio, Inc. | METHODS FOR SELECTIVE EXPANSION OF γδ T-CELL POPULATIONS AND COMPOSITIONS THEREOF |
| AU2017306432A1 (en) | 2016-08-02 | 2019-03-21 | TCR2 Therapeutics Inc. | Compositions and methods for TCR reprogramming using fusion proteins |
| US10576167B2 (en) | 2016-08-17 | 2020-03-03 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| BR112019007100A2 (pt) | 2016-10-07 | 2019-06-25 | Tcr2 Therapeutics Inc | composições e métodos para reprogramação de receptores de célula t com o uso de proteínas de fusão |
| CA3041068A1 (en) | 2016-10-18 | 2018-04-26 | Regents Of The University Of Minnesota | Tumor infiltrating lymphocytes and methods of therapy |
| CA3044593A1 (en) | 2016-11-22 | 2018-05-31 | TCR2 Therapeutics Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
| US20210187022A1 (en) | 2016-12-21 | 2021-06-24 | TCR2 Therapeutics Inc. | Engineered t cells for the treatment of cancer |
| US12344826B2 (en) | 2017-01-25 | 2025-07-01 | The George Washington University, A Congressionally Chartered Not-For-Profit Corporation | Apparatus and methods for in vitro preclinical human trials |
| TW201839136A (zh) | 2017-02-06 | 2018-11-01 | 瑞士商諾華公司 | 治療血色素異常症之組合物及方法 |
| US20190365929A1 (en) * | 2017-02-22 | 2019-12-05 | Crispr Therapeutics Ag | Materials and methods for treatment of dystrophic epidermolysis bullosa (deb) and other collagen type vii alpha 1 chain (col7a1) gene related conditions or disorders |
| CA3066047A1 (en) | 2017-06-14 | 2018-12-20 | Technische Universitat Dresden | Methods and means for genetic alteration of genomes utilizing designer dna recombining enzymes |
| JP7712643B2 (ja) | 2017-06-19 | 2025-07-24 | 国立大学法人東北大学 | 表皮水疱症の治療剤 |
| JP2020530307A (ja) | 2017-06-30 | 2020-10-22 | インティマ・バイオサイエンス，インコーポレーテッド | 遺伝子治療のためのアデノ随伴ウイルスベクター |
| WO2019099744A1 (en) | 2017-11-15 | 2019-05-23 | Adicet Bio, Inc. | METHODS FOR SELECTIVE EXPANSION OF δ3 γδ T-CELL POPULATIONS AND COMPOSITIONS THEREOF |
| EP3775236A1 (en) | 2018-04-12 | 2021-02-17 | Krystal Biotech, LLC | Compositions and methods for the treatment of autosomal recessive congenital ichthyosis |
| US11981892B2 (en) | 2018-04-16 | 2024-05-14 | University Of Massachusetts | Compositions and methods for improved gene editing |
| MX2020011257A (es) | 2018-04-27 | 2021-01-15 | Krystal Biotech Inc | Ácidos nucleicos recombinantes que codifican una o más proteínas cosméticas para usos estéticos. |
| EP3806961A4 (en) | 2018-05-11 | 2022-10-19 | Memorial Sloan Kettering Cancer Center | T LYMPHOCYTE RECEPTORS TARGETING PIK3CA MUTATIONS AND THEIR USES |
| IL279271B2 (en) | 2018-06-07 | 2025-05-01 | The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization Aro Vo | Methods for Cannabis Regeneration and Transformation |
| CN112424365A (zh) | 2018-06-07 | 2021-02-26 | 以色列国家农业部、农村发展农业研究组织·沃尔卡尼中心 | 核酸构建体及其使用方法 |
| WO2020051453A1 (en) * | 2018-09-07 | 2020-03-12 | Wisconsin Alumni Research Foundation | Generation of hematopoietic progenitor cells from human pluripotent stem cells |
| AU2019346549B2 (en) | 2018-09-24 | 2024-09-12 | Krystal Biotech, Inc. | Compositions and methods for the treatment of Netherton Syndrome |
| WO2020112860A1 (en) | 2018-11-30 | 2020-06-04 | Intima Bioscience, Inc. | Methods of identifying immunomodulatory genes |
| CA3126896A1 (en) | 2018-12-03 | 2020-06-11 | Adicet Bio Inc. | Methods for selective in vivo expansion of .gamma. .delta. t-cell populations and compositions thereof |
| SG11202107969SA (en) | 2019-02-08 | 2021-08-30 | Krystal Biotech Inc | Compositions and methods for delivering cftr polypeptides |
| KR20220004060A (ko) | 2019-04-05 | 2022-01-11 | 루트패스 제노믹스, 인크. | T-세포 수용체 유전자 어셈블리를 위한 조성물 및 방법 |
| JP2022536364A (ja) | 2019-06-13 | 2022-08-15 | ザ ジェネラル ホスピタル コーポレイション | 操作されたヒト内在性ウイルス様粒子および細胞への送達のためのその使用方法 |
| EP3987024A4 (en) | 2019-06-20 | 2023-11-01 | University Of Massachusetts | COMPOSITIONS AND METHODS FOR ENHANCED GENOMIC EDITING |
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| EP4493681A1 (en) | 2022-03-17 | 2025-01-22 | Keshihua (Nanjing) Biotechnology Co., Ltd | Synthetic tumor-infiltrating lymphocytes (tils) |
| WO2024039576A2 (en) | 2022-08-19 | 2024-02-22 | Memorial Sloan-Kettering Cancer Center | T cell receptors targeting ras mutations and uses thereof |
| EP4619513A1 (en) | 2022-11-18 | 2025-09-24 | Kyoto Prefectural Public University Corporation | Compositions for mitophagy induction and uses thereof |
| WO2025128981A1 (en) | 2023-12-14 | 2025-06-19 | Sohm, Inc. | Compositions and methods for genome editing |
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| AU2010360293B2 (en) * | 2010-09-06 | 2016-06-16 | Temasek Life Sciences Laboratory Limited | Molecular interaction between Xa10 and AvrXa10 |
| EP3498833B1 (en) * | 2011-09-21 | 2023-08-16 | Sangamo Therapeutics, Inc. | Methods and compositions for regulation of transgene expression |
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| US20210187006A1 (en) | 2021-06-24 |
| HK1219021A1 (en) | 2017-03-24 |
| JP2021088565A (ja) | 2021-06-10 |
| EP2961262B1 (en) | 2019-07-24 |
| AU2014223243A1 (en) | 2015-09-10 |
| CA2902954A1 (en) | 2014-09-04 |
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| US10973844B2 (en) | 2021-04-13 |
| US10172880B2 (en) | 2019-01-08 |
| ES2750550T3 (es) | 2020-03-26 |
| NZ711254A (en) | 2021-02-26 |
| AU2020200307A1 (en) | 2020-02-06 |
| JP2016512960A (ja) | 2016-05-12 |
| US20160367588A1 (en) | 2016-12-22 |
| WO2014134412A1 (en) | 2014-09-04 |
| EP3567104A1 (en) | 2019-11-13 |
| US20190054111A1 (en) | 2019-02-21 |
| US9393257B2 (en) | 2016-07-19 |
| JP6893945B2 (ja) | 2021-06-23 |
| EP2961262A4 (en) | 2016-10-12 |
| US20140256798A1 (en) | 2014-09-11 |
| EP2961262A1 (en) | 2016-01-06 |
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