CA2902954A1 - Talen-based gene correction - Google Patents
Talen-based gene correction Download PDFInfo
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- CA2902954A1 CA2902954A1 CA2902954A CA2902954A CA2902954A1 CA 2902954 A1 CA2902954 A1 CA 2902954A1 CA 2902954 A CA2902954 A CA 2902954A CA 2902954 A CA2902954 A CA 2902954A CA 2902954 A1 CA2902954 A1 CA 2902954A1
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- C—CHEMISTRY; METALLURGY
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| US61/771,735 | 2013-03-01 | ||
| PCT/US2014/019322 WO2014134412A1 (en) | 2013-03-01 | 2014-02-28 | Talen-based gene correction |
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| CA2902954A1 true CA2902954A1 (en) | 2014-09-04 |
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| CA2902954A Abandoned CA2902954A1 (en) | 2013-03-01 | 2014-02-28 | Talen-based gene correction |
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| JP (3) | JP6480874B2 (OSRAM) |
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| CA (1) | CA2902954A1 (OSRAM) |
| ES (1) | ES2750550T3 (OSRAM) |
| WO (1) | WO2014134412A1 (OSRAM) |
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| US9850497B2 (en) * | 2013-11-04 | 2017-12-26 | Regents Of The University Of Minnesota | Gene targeting methods and tools |
| US9770489B2 (en) * | 2014-01-31 | 2017-09-26 | Factor Bioscience Inc. | Methods and products for nucleic acid production and delivery |
| WO2016081518A2 (en) | 2014-11-17 | 2016-05-26 | Adicet Bio, Inc. | Engineered gamma delta t-cells |
| US11241505B2 (en) | 2015-02-13 | 2022-02-08 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| CN104726495B (zh) * | 2015-03-25 | 2018-06-19 | 西北农林科技大学 | 一种基于talen介导的基因打靶敲除山羊blg的载体及重组细胞 |
| JP2018513681A (ja) | 2015-03-31 | 2018-05-31 | エクセリゲン サイエンティフィック, インコーポレイテッドExeligen Scientific, Inc. | 細胞または生物のゲノムへのＤＮＡ配列の標的化組み込みのためのＣａｓ９レトロウイルスインテグラーゼおよびＣａｓ９レコンビナーゼ系 |
| CN108026566A (zh) | 2015-05-04 | 2018-05-11 | 特拉维夫大学拉莫特有限公司 | 用于使dna片段化的方法和试剂盒 |
| DK3298033T4 (da) | 2015-05-18 | 2023-10-02 | Tcr2 Therapeutics Inc | Sammensætninger og medicinske anvendelser til tcr-reprogrammering under anvendelse af fusionsproteiner |
| WO2017023803A1 (en) | 2015-07-31 | 2017-02-09 | Regents Of The University Of Minnesota | Modified cells and methods of therapy |
| WO2017075248A1 (en) * | 2015-10-27 | 2017-05-04 | The Board Of Trustees Of The Leland Stanford Junior University | Treatment of epidermolysis bullosa by injection of autologous collagen vii overexpressing leukocytes |
| HUE049237T2 (hu) * | 2016-04-08 | 2020-09-28 | Krystal Biotech Inc | Készítmények a bõr sérülései, rendellenességei és betegségei kezelési eljárásaiban történõ alkalmazásra |
| EP3454870A4 (en) | 2016-05-12 | 2020-03-04 | Adicet Bio Inc. | METHOD FOR SELECTIVE EXPANSION OF GAMMA DELTA T CELL POPULATIONS AND COMPOSITIONS THEREOF |
| JP7109789B2 (ja) | 2016-08-02 | 2022-08-01 | ティーシーアール２ セラピューティクス インク． | 融合タンパク質を使用したｔｃｒの再プログラム化のための組成物及び方法 |
| US10576167B2 (en) | 2016-08-17 | 2020-03-03 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| CA3036745A1 (en) | 2016-10-07 | 2018-04-12 | TCR2 Therapeutics Inc. | Compositions and methods for t-cell receptors reprogramming using fusion proteins |
| CA3041068A1 (en) | 2016-10-18 | 2018-04-26 | Regents Of The University Of Minnesota | Tumor infiltrating lymphocytes and methods of therapy |
| CA3044593A1 (en) | 2016-11-22 | 2018-05-31 | TCR2 Therapeutics Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
| AU2017382902A1 (en) | 2016-12-21 | 2019-07-18 | TCR2 Therapeutics Inc. | Engineered T cells for the treatment of cancer |
| US12344826B2 (en) | 2017-01-25 | 2025-07-01 | The George Washington University, A Congressionally Chartered Not-For-Profit Corporation | Apparatus and methods for in vitro preclinical human trials |
| TW201839136A (zh) | 2017-02-06 | 2018-11-01 | 瑞士商諾華公司 | 治療血色素異常症之組合物及方法 |
| EP3585897A1 (en) * | 2017-02-22 | 2020-01-01 | CRISPR Therapeutics AG | Materials and methods for treatment of dystrophic epidermolysis bullosa (deb) and other collagen type vii alpha 1 chain (col7a1) gene related conditions or disorders |
| FI3638776T3 (fi) | 2017-06-14 | 2025-12-09 | Univ Dresden Tech | Menetelmiä ja välineitä genomien geneettiseen muokkaamiseen hyödyntäen suunnittelu-DNA:ta rekombinoivia entsyymejä |
| EP3643316A4 (en) | 2017-06-19 | 2021-01-20 | National University Corporation Hokkaido University | TREATMENT PRODUCTS FOR EPIDERMOLYSIS BULLOSA |
| JP2020530307A (ja) | 2017-06-30 | 2020-10-22 | インティマ・バイオサイエンス，インコーポレーテッド | 遺伝子治療のためのアデノ随伴ウイルスベクター |
| IL274640B1 (en) | 2017-11-15 | 2025-10-01 | Adicet Bio Inc | Methods for selective expansion of delta 3 gamma-delta T-cell populations and preparations thereof |
| CA3094345A1 (en) | 2018-04-12 | 2019-10-17 | Krystal Biotech, Inc. | Compositions and methods for the treatment of autosomal recessive congenital ichthyosis |
| EP3781677A4 (en) | 2018-04-16 | 2022-01-19 | University of Massachusetts | COMPOSITIONS AND METHODS FOR IMPROVED GENE EDITTING |
| WO2019210219A1 (en) | 2018-04-27 | 2019-10-31 | Krystal Biotech, Inc. | Recombinant nucleic acids encoding cosmetic protein(s) for aesthetic applications |
| WO2019217837A1 (en) | 2018-05-11 | 2019-11-14 | Memorial Sloan-Kettering Cancer Center | T cell receptors targeting pik3ca mutations and uses thereof |
| EP3802839A1 (en) | 2018-06-07 | 2021-04-14 | The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center) | Nucleic acid constructs and methods of using same |
| CN112384063A (zh) | 2018-06-07 | 2021-02-19 | 以色列国家农业部、农村发展农业研究组织·沃尔卡尼中心 | 再生及转殖大麻的方法 |
| CA3109546A1 (en) | 2018-09-07 | 2020-03-12 | Wisconsin Alumni Research Foundation | Generation of hematopoietic progenitor cells from human pluripotent stem cells |
| US20200093874A1 (en) | 2018-09-24 | 2020-03-26 | Krystal Biotech, Inc. | Compositions and methods for the treatment of netherton syndrome |
| WO2020112860A1 (en) | 2018-11-30 | 2020-06-04 | Intima Bioscience, Inc. | Methods of identifying immunomodulatory genes |
| CA3126896A1 (en) | 2018-12-03 | 2020-06-11 | Adicet Bio Inc. | Methods for selective in vivo expansion of .gamma. .delta. t-cell populations and compositions thereof |
| EP3921334A1 (en) | 2019-02-08 | 2021-12-15 | Krystal Biotech, Inc. | Compositions and methods for delivering cftr polypeptides |
| KR20220004060A (ko) | 2019-04-05 | 2022-01-11 | 루트패스 제노믹스, 인크. | T-세포 수용체 유전자 어셈블리를 위한 조성물 및 방법 |
| WO2020252455A1 (en) | 2019-06-13 | 2020-12-17 | The General Hospital Corporation | Engineered human-endogenous virus-like particles and methods of use thereof for delivery to cells |
| EP3987024A4 (en) | 2019-06-20 | 2023-11-01 | University Of Massachusetts | COMPOSITIONS AND METHODS FOR ENHANCED GENOMIC EDITING |
| JP7730298B2 (ja) | 2019-06-20 | 2025-08-27 | メモリアル スローン ケタリング キャンサー センター | Ｐｉｋ３ｃａ変異を標的にするｔ細胞レセプターおよびその使用 |
| KR20220039719A (ko) | 2019-07-03 | 2022-03-29 | 팩터 바이오사이언스 인크. | 양이온성 지질 및 이의 용도 |
| EP3999627A2 (en) | 2019-07-18 | 2022-05-25 | University of Rochester | Cell-type selective immunoprotection of cells |
| US10501404B1 (en) | 2019-07-30 | 2019-12-10 | Factor Bioscience Inc. | Cationic lipids and transfection methods |
| GB2628935B (en) | 2019-09-03 | 2025-03-05 | Myeloid Therapeutics Inc | Methods and compositions for genomic integration |
| WO2021191870A1 (en) | 2020-03-27 | 2021-09-30 | Dcprime B.V. | Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy |
| EP4171617A1 (en) | 2020-06-30 | 2023-05-03 | Mendus B.V. | Use of leukemia-derived cells in ovarian cancer vaccines |
| CN116670154A (zh) | 2020-07-24 | 2023-08-29 | 总医院公司 | 增强的病毒样颗粒及使用其递送至细胞的方法 |
| JP2023539700A (ja) | 2020-09-01 | 2023-09-15 | ６４－エックス， インコーポレイテッド | 哺乳動物細胞及びその改変方法 |
| WO2022087380A1 (en) | 2020-10-23 | 2022-04-28 | Rootpath Genomics, Inc. | Compositions and methods for t-cell receptor identification |
| EP4277933A4 (en) | 2021-01-14 | 2024-12-11 | Senti Biosciences, Inc. | SECRETABLE PAYLOAD REGULATION |
| KR20230135075A (ko) | 2021-01-22 | 2023-09-22 | 멘두스 비.브이. | 종양 백신접종 방법 |
| US20220305100A1 (en) | 2021-03-12 | 2022-09-29 | Dcprime B.V. | Methods of vaccination and use of cd47 blockade |
| CN117412986A (zh) | 2021-04-02 | 2024-01-16 | 克里斯托生物技术股份有限公司 | 用于癌症疗法的病毒载体 |
| AU2022272235A1 (en) | 2021-05-11 | 2023-12-21 | Myeloid Therapeutics, Inc. | Methods and compositions for genomic integration |
| US11753677B2 (en) | 2021-11-10 | 2023-09-12 | Encodia, Inc. | Methods for barcoding macromolecules in individual cells |
| US20250205335A1 (en) | 2022-03-17 | 2025-06-26 | Hangzhou Chengyuan Biotechnology Co., Ltd. | Synthetic tumor-infiltrating lymphocytes (tils) |
| WO2024039576A2 (en) | 2022-08-19 | 2024-02-22 | Memorial Sloan-Kettering Cancer Center | T cell receptors targeting ras mutations and uses thereof |
| EP4619513A1 (en) | 2022-11-18 | 2025-09-24 | Kyoto Prefectural Public University Corporation | Compositions for mitophagy induction and uses thereof |
| WO2025128981A1 (en) | 2023-12-14 | 2025-06-19 | Sohm, Inc. | Compositions and methods for genome editing |
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| ES2696825T3 (es) | 2009-12-10 | 2019-01-18 | Univ Minnesota | Modificación del ADN inducida por el efector TAL |
| CN103210087B (zh) | 2010-09-06 | 2015-04-29 | 淡马锡生命科学研究院有限公司 | Xa10与AvrXa10之间的分子相互作用 |
| EP3260540A1 (en) * | 2010-11-12 | 2017-12-27 | The General Hospital Corporation | Polycomb-associated non-coding rnas |
| KR102061557B1 (ko) * | 2011-09-21 | 2020-01-03 | 상가모 테라퓨틱스, 인코포레이티드 | 이식 유전자 발현의 조절을 위한 방법 및 조성물 |
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| US20190054111A1 (en) | 2019-02-21 |
| US20140256798A1 (en) | 2014-09-11 |
| US10973844B2 (en) | 2021-04-13 |
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| AU2020200307A1 (en) | 2020-02-06 |
| US20160367588A1 (en) | 2016-12-22 |
| US9393257B2 (en) | 2016-07-19 |
| JP2021088565A (ja) | 2021-06-10 |
| JP6480874B2 (ja) | 2019-03-13 |
| AU2014223243A1 (en) | 2015-09-10 |
| AU2014223243B2 (en) | 2019-10-17 |
| US10172880B2 (en) | 2019-01-08 |
| US20210187006A1 (en) | 2021-06-24 |
| JP6893945B2 (ja) | 2021-06-23 |
| EP2961262A4 (en) | 2016-10-12 |
| JP2016512960A (ja) | 2016-05-12 |
| JP2019089821A (ja) | 2019-06-13 |
| WO2014134412A1 (en) | 2014-09-04 |
| NZ711254A (en) | 2021-02-26 |
| EP2961262B1 (en) | 2019-07-24 |
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