AU2012278802B2 - Assays for detecting neutralizing autoantibodies to biologic therapy with TNF alpha - Google Patents
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- AU2012278802B2 AU2012278802B2 AU2012278802A AU2012278802A AU2012278802B2 AU 2012278802 B2 AU2012278802 B2 AU 2012278802B2 AU 2012278802 A AU2012278802 A AU 2012278802A AU 2012278802 A AU2012278802 A AU 2012278802A AU 2012278802 B2 AU2012278802 B2 AU 2012278802B2
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Classifications
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- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
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- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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Landscapes
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| WO2010062627A2 (en) | 2008-10-27 | 2010-06-03 | Genalyte Inc. | Biosensors based on optical probing and sensing |
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| AU2011317149B2 (en) | 2010-10-18 | 2015-05-07 | Société des Produits Nestlé S.A. | Methods for determining anti-drug antibody isotypes |
| RU2013158256A (ru) | 2011-07-06 | 2015-07-10 | Нестек С.А. | АНАЛИЗЫ ДЛЯ ОБНАРУЖЕНИЯ НЕЙТРАЛИЗУЮЩИХ АУТОАНТИТЕЛ ДЛЯ БИОЛОГИЧЕСКОЙ ТЕРАПИИ TNFα |
| MX358730B (es) | 2012-10-05 | 2018-09-03 | Nestec Sa | Metodos para predecir y monitorear cicatrizacion de la mucosa. |
| BR112015012482A2 (pt) * | 2012-11-30 | 2017-07-11 | Nestec Sa | ensaios para detecção de autoanticorpos neutralizantes à terapia com produtos biológicos |
| WO2014122600A1 (en) | 2013-02-05 | 2014-08-14 | Nestec S.A. | Methods of selecting combination therapy for colorectal cancer patients |
| EP3022295A4 (en) | 2013-07-19 | 2017-03-01 | Cedars-Sinai Medical Center | Signature of tl1a (tnfsf15) signaling pathway |
| EP3654037A1 (en) | 2013-12-03 | 2020-05-20 | Prometheus Biosciences, Inc. | Methods for predicting post-operative recurrence of crohn's disease |
| WO2015110989A1 (en) | 2014-01-23 | 2015-07-30 | Nestec S.A. | Biomarker panel for assessment of mucosal healing |
| ES2735085T3 (es) * | 2014-12-05 | 2019-12-16 | Nestle Sa | Ensayos de cambio de movilidad homogéneos indirectos para la detección de agentes biológicos en muestras de pacientes |
| CN105277682A (zh) * | 2015-11-17 | 2016-01-27 | 苏州浩欧博生物医药有限公司 | 一种抗TNF-α单抗药物抗体检测试剂盒 |
| EP3482199A1 (en) * | 2016-07-08 | 2019-05-15 | Atonomics A/S | A universal assay for determining the quantity of therapeutic monoclonal antibodies and their corresponding anti-drug-antibodies in samples |
| WO2020263450A1 (en) * | 2019-06-25 | 2020-12-30 | Procisedx Inc. | Detection of anti-tnf alpha drug biologics and anti-drug antibodies |
| KR102626197B1 (ko) * | 2020-11-19 | 2024-01-18 | 바디텍메드(주) | 항 약물 항체의 수준을 정확하게 정량화하는 방법 |
| CN112730846B (zh) * | 2020-12-18 | 2023-12-15 | 安渡生物医药(杭州)有限公司 | 一种用于小鼠血样检测免疫复合物的方法 |
| CN114236139A (zh) * | 2021-12-30 | 2022-03-25 | 苏州和锐生物科技有限公司 | 一种TNF-α生物制剂的抗体检测试剂盒、制备方法 |
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| HK1194467A1 (zh) | 2014-10-17 |
| JP2014525036A (ja) | 2014-09-25 |
| MX343324B (es) | 2016-11-01 |
| EP3130921B1 (en) | 2018-09-12 |
| RU2013158256A (ru) | 2015-07-10 |
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| KR20140047628A (ko) | 2014-04-22 |
| AU2016201196A1 (en) | 2016-03-17 |
| US9465027B2 (en) | 2016-10-11 |
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| ZA201309703B (en) | 2019-09-25 |
| EP3130921A1 (en) | 2017-02-15 |
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| AU2012278802A1 (en) | 2013-05-02 |
| MX2013015420A (es) | 2015-01-22 |
| US10794906B2 (en) | 2020-10-06 |
| EP2729807B1 (en) | 2016-08-17 |
| CN103782172A (zh) | 2014-05-07 |
| EP2729807A1 (en) | 2014-05-14 |
| US20140186973A1 (en) | 2014-07-03 |
| WO2013006810A1 (en) | 2013-01-10 |
| CA2840232A1 (en) | 2013-01-10 |
| NZ619172A (en) | 2016-01-29 |
| AU2016201196B2 (en) | 2018-01-25 |
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