AU2011303467C1 - Method for separating target molecules or particles from fibrinogen-containing samples including blood components - Google Patents

Method for separating target molecules or particles from fibrinogen-containing samples including blood components Download PDF

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Publication number
AU2011303467C1
AU2011303467C1 AU2011303467A AU2011303467A AU2011303467C1 AU 2011303467 C1 AU2011303467 C1 AU 2011303467C1 AU 2011303467 A AU2011303467 A AU 2011303467A AU 2011303467 A AU2011303467 A AU 2011303467A AU 2011303467 C1 AU2011303467 C1 AU 2011303467C1
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sample
fibrinogen
fibrin
particles
thrombin
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AU2011303467A
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AU2011303467B2 (en
AU2011303467A1 (en
Inventor
Patrice Francois
Vladimir Lazarevic
Nicolas Mermod
Amar Rida
Jacques Schrenzel
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Debiopharm International SA
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Debiopharm International SA
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Publication of AU2011303467B2 publication Critical patent/AU2011303467B2/en
Priority to AU2016266066A priority Critical patent/AU2016266066B2/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56938Staphylococcus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/14Streptococcus; Staphylococcus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745Assays involving non-enzymic blood coagulation factors
    • G01N2333/75Fibrin; Fibrinogen
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974Thrombin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
AU2011303467A 2010-09-15 2011-09-15 Method for separating target molecules or particles from fibrinogen-containing samples including blood components Active AU2011303467C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2016266066A AU2016266066B2 (en) 2010-09-15 2016-12-02 Method for separating target molecules or particles from fibrinogen-containing samples including blood components

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
CH01478/10 2010-09-15
CH14782010 2010-09-15
CH20412010 2010-12-07
CH02041/10 2010-12-07
CH01207/11 2011-07-20
CH12072011 2011-07-20
PCT/IB2011/054035 WO2012035508A2 (en) 2010-09-15 2011-09-15 Method for separating target molecules or particles from fibrinogen-containing samples including blood components

Related Child Applications (1)

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AU2016266066A Division AU2016266066B2 (en) 2010-09-15 2016-12-02 Method for separating target molecules or particles from fibrinogen-containing samples including blood components

Publications (3)

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AU2011303467A1 AU2011303467A1 (en) 2013-04-04
AU2011303467B2 AU2011303467B2 (en) 2016-09-15
AU2011303467C1 true AU2011303467C1 (en) 2017-03-09

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AU2016266066A Active AU2016266066B2 (en) 2010-09-15 2016-12-02 Method for separating target molecules or particles from fibrinogen-containing samples including blood components

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US (4) US9689881B2 (enExample)
EP (2) EP2616550B1 (enExample)
JP (1) JP5999776B2 (enExample)
KR (1) KR101948944B1 (enExample)
CN (2) CN107389932B (enExample)
AU (2) AU2011303467C1 (enExample)
CA (1) CA2811493C (enExample)
CY (1) CY1122166T1 (enExample)
DK (2) DK2616550T3 (enExample)
ES (2) ES2751660T3 (enExample)
HR (1) HRP20191785T1 (enExample)
HU (2) HUE028915T2 (enExample)
LT (1) LT3067431T (enExample)
PL (2) PL2616550T3 (enExample)
PT (1) PT3067431T (enExample)
SI (1) SI3067431T1 (enExample)
WO (1) WO2012035508A2 (enExample)

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* Cited by examiner, † Cited by third party
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US9689881B2 (en) 2010-09-15 2017-06-27 Spinomix S.A. Method for separating target molecules or particles from fibrinogen-containing samples including blood components
CN103702674B (zh) 2011-06-27 2018-05-29 爱默蕾大学 血小板裂解物的组合物、用途和制备
EP2979093B1 (en) * 2013-03-29 2019-10-23 Siemens Healthcare Diagnostics Inc. Rare cell concentration
ES2740838T3 (es) * 2014-06-01 2020-02-06 Debiopharm Int Sa Dispositivo de recolección y procesamiento de muestras
US12397302B2 (en) 2015-11-30 2025-08-26 Dh Technologies Development Pte. Ltd. Electromagnetic assemblies for processing fluids
WO2017156375A1 (en) 2016-03-10 2017-09-14 Arthrex, Inc. Systems and methods for preparing a thrombin serum
WO2017156379A2 (en) 2016-03-10 2017-09-14 Arthrex, Inc. Systems and methods for preparing protein enhanced serums
KR20210052389A (ko) 2018-08-27 2021-05-10 리제너론 파마슈티칼스 인코포레이티드 다운스트림 정제에서의 라만 분광법의 사용
JP7298449B2 (ja) * 2019-11-14 2023-06-27 株式会社島津製作所 血液凝固分析装置、及び分注ノズルの洗浄方法

Citations (4)

* Cited by examiner, † Cited by third party
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US20030068662A1 (en) * 1987-12-24 2003-04-10 Institut Pasteur Reagent for the detection of Staphylococcus aureus by agglutination
US6680195B1 (en) * 1997-11-26 2004-01-20 Inhibitex, Inc. Extracellular matrix-binding proteins from staphylococcus aureus
WO2007015782A1 (en) * 2005-07-29 2007-02-08 Ecole Polytechnique Federale De Lausanne Molecular variant fibrinogen fusion proteins
WO2010004004A1 (en) * 2008-07-09 2010-01-14 Profibrix Bv Recombinant fibrinogen

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DE3803463A1 (de) * 1988-02-05 1989-08-17 Linhart Axel Semiquantitativer kalzium-schnelltest
US5691160A (en) * 1992-08-14 1997-11-25 Biogen, Inc. Effects of actin filaments of fibrin clot structure and lysis
EP0587398B1 (en) * 1992-09-09 1998-01-14 Tokuyama Corporation Method of assaying fibrinogen, dry reagent therefor, and process for the preparation thereof
JP3292760B2 (ja) * 1993-04-22 2002-06-17 テルモ株式会社 採血管およびその製造方法
US5670329A (en) * 1993-05-28 1997-09-23 Cardiovascular Diagnostics, Inc. Method and analytical system for performing fibrinogen assays accurately, rapidly and simply using a rotating magnetic field
WO1995015397A1 (en) 1993-12-03 1995-06-08 Dorn Gordon L Method for improving quantitative recovery of microorganisms fro m specimens containing blood components
DE19602673A1 (de) * 1996-01-25 1997-08-07 Pereg Gmbh Synthetische Testanschmutzung
US6121232A (en) * 1997-01-31 2000-09-19 Omrix Biopharmaceuticals Sa Stabilized mixture comprising fibrinogen
JP2000262499A (ja) * 2000-01-01 2000-09-26 Terumo Corp 採血管
US6686204B2 (en) * 2001-08-27 2004-02-03 Becton, Dickinson & Company Collection device
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JP4718833B2 (ja) * 2002-05-01 2011-07-06 シナプス ベスローテン フェンノートシャップ 複合生物媒体における、一時的なタンパク質分解活性の濃度を決定するための診断試験
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US20030068662A1 (en) * 1987-12-24 2003-04-10 Institut Pasteur Reagent for the detection of Staphylococcus aureus by agglutination
US6680195B1 (en) * 1997-11-26 2004-01-20 Inhibitex, Inc. Extracellular matrix-binding proteins from staphylococcus aureus
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WO2010004004A1 (en) * 2008-07-09 2010-01-14 Profibrix Bv Recombinant fibrinogen

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Also Published As

Publication number Publication date
KR20130107300A (ko) 2013-10-01
KR101948944B1 (ko) 2019-02-15
US20210148940A1 (en) 2021-05-20
AU2011303467B2 (en) 2016-09-15
US20130164737A1 (en) 2013-06-27
CA2811493A1 (en) 2012-03-22
JP5999776B2 (ja) 2016-09-28
EP3067431A1 (en) 2016-09-14
EP2616550A2 (en) 2013-07-24
WO2012035508A3 (en) 2012-05-18
PT3067431T (pt) 2019-10-29
ES2571127T3 (es) 2016-05-24
WO2012035508A2 (en) 2012-03-22
EP2616550B1 (en) 2016-02-10
CN103108959A (zh) 2013-05-15
HRP20191785T1 (hr) 2019-12-27
HUE028915T2 (en) 2017-01-30
JP2013538355A (ja) 2013-10-10
AU2016266066A1 (en) 2016-12-22
PL2616550T3 (pl) 2016-08-31
SI3067431T1 (sl) 2019-11-29
HK1247280A1 (zh) 2018-09-21
DK3067431T3 (da) 2019-10-14
CN107389932B (zh) 2019-11-22
WO2012035508A4 (en) 2012-07-19
AU2016266066B2 (en) 2017-12-21
EP3067431B1 (en) 2019-07-24
HUE045771T2 (hu) 2020-01-28
US20170336424A1 (en) 2017-11-23
US9689881B2 (en) 2017-06-27
CA2811493C (en) 2020-06-16
CY1122166T1 (el) 2020-11-25
PL3067431T3 (pl) 2019-12-31
DK2616550T3 (en) 2016-05-23
ES2751660T3 (es) 2020-04-01
AU2011303467A1 (en) 2013-04-04
US20240280593A1 (en) 2024-08-22
CN107389932A (zh) 2017-11-24
CN103108959B (zh) 2017-06-09
LT3067431T (lt) 2019-11-11

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DA2 Applications for amendment section 104

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