JP5999776B2 - 血液成分を含むフィブリノゲン含有サンプルからターゲット分子又は粒子を分離する方法 - Google Patents

血液成分を含むフィブリノゲン含有サンプルからターゲット分子又は粒子を分離する方法 Download PDF

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JP5999776B2
JP5999776B2 JP2013528815A JP2013528815A JP5999776B2 JP 5999776 B2 JP5999776 B2 JP 5999776B2 JP 2013528815 A JP2013528815 A JP 2013528815A JP 2013528815 A JP2013528815 A JP 2013528815A JP 5999776 B2 JP5999776 B2 JP 5999776B2
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sample
fibrinogen
fibrin
thrombin
target
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JP2013538355A5 (enExample
JP2013538355A (ja
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リダー，アマル
メルモ，ニコラ
フランソワ，パトリス
ラザレヴィチ，ウラディミール
シュレンゼル，ジャック
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Debiopharm International SA
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56938—Staphylococcus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/14—Streptococcus; Staphylococcus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/75—Fibrin; Fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
JP2013528815A 2010-09-15 2011-09-15 血液成分を含むフィブリノゲン含有サンプルからターゲット分子又は粒子を分離する方法 Active JP5999776B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
CH01478/10 2010-09-15
CH14782010 2010-09-15
CH20412010 2010-12-07
CH02041/10 2010-12-07
CH01207/11 2011-07-20
CH12072011 2011-07-20
PCT/IB2011/054035 WO2012035508A2 (en) 2010-09-15 2011-09-15 Method for separating target molecules or particles from fibrinogen-containing samples including blood components

Publications (3)

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JP2013538355A JP2013538355A (ja) 2013-10-10
JP2013538355A5 JP2013538355A5 (enExample) 2015-08-06
JP5999776B2 true JP5999776B2 (ja) 2016-09-28

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JP2013528815A Active JP5999776B2 (ja) 2010-09-15 2011-09-15 血液成分を含むフィブリノゲン含有サンプルからターゲット分子又は粒子を分離する方法

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US (4) US9689881B2 (enExample)
EP (2) EP2616550B1 (enExample)
JP (1) JP5999776B2 (enExample)
KR (1) KR101948944B1 (enExample)
CN (2) CN107389932B (enExample)
AU (2) AU2011303467C1 (enExample)
CA (1) CA2811493C (enExample)
CY (1) CY1122166T1 (enExample)
DK (2) DK2616550T3 (enExample)
ES (2) ES2751660T3 (enExample)
HR (1) HRP20191785T1 (enExample)
HU (2) HUE028915T2 (enExample)
LT (1) LT3067431T (enExample)
PL (2) PL2616550T3 (enExample)
PT (1) PT3067431T (enExample)
SI (1) SI3067431T1 (enExample)
WO (1) WO2012035508A2 (enExample)

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US9689881B2 (en) 2010-09-15 2017-06-27 Spinomix S.A. Method for separating target molecules or particles from fibrinogen-containing samples including blood components
CN103702674B (zh) 2011-06-27 2018-05-29 爱默蕾大学 血小板裂解物的组合物、用途和制备
EP2979093B1 (en) * 2013-03-29 2019-10-23 Siemens Healthcare Diagnostics Inc. Rare cell concentration
ES2740838T3 (es) * 2014-06-01 2020-02-06 Debiopharm Int Sa Dispositivo de recolección y procesamiento de muestras
US12397302B2 (en) 2015-11-30 2025-08-26 Dh Technologies Development Pte. Ltd. Electromagnetic assemblies for processing fluids
WO2017156375A1 (en) 2016-03-10 2017-09-14 Arthrex, Inc. Systems and methods for preparing a thrombin serum
WO2017156379A2 (en) 2016-03-10 2017-09-14 Arthrex, Inc. Systems and methods for preparing protein enhanced serums
KR20210052389A (ko) 2018-08-27 2021-05-10 리제너론 파마슈티칼스 인코포레이티드 다운스트림 정제에서의 라만 분광법의 사용
JP7298449B2 (ja) * 2019-11-14 2023-06-27 株式会社島津製作所 血液凝固分析装置、及び分注ノズルの洗浄方法

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Also Published As

Publication number Publication date
KR20130107300A (ko) 2013-10-01
KR101948944B1 (ko) 2019-02-15
US20210148940A1 (en) 2021-05-20
AU2011303467B2 (en) 2016-09-15
US20130164737A1 (en) 2013-06-27
CA2811493A1 (en) 2012-03-22
AU2011303467C1 (en) 2017-03-09
EP3067431A1 (en) 2016-09-14
EP2616550A2 (en) 2013-07-24
WO2012035508A3 (en) 2012-05-18
PT3067431T (pt) 2019-10-29
ES2571127T3 (es) 2016-05-24
WO2012035508A2 (en) 2012-03-22
EP2616550B1 (en) 2016-02-10
CN103108959A (zh) 2013-05-15
HRP20191785T1 (hr) 2019-12-27
HUE028915T2 (en) 2017-01-30
JP2013538355A (ja) 2013-10-10
AU2016266066A1 (en) 2016-12-22
PL2616550T3 (pl) 2016-08-31
SI3067431T1 (sl) 2019-11-29
HK1247280A1 (zh) 2018-09-21
DK3067431T3 (da) 2019-10-14
CN107389932B (zh) 2019-11-22
WO2012035508A4 (en) 2012-07-19
AU2016266066B2 (en) 2017-12-21
EP3067431B1 (en) 2019-07-24
HUE045771T2 (hu) 2020-01-28
US20170336424A1 (en) 2017-11-23
US9689881B2 (en) 2017-06-27
CA2811493C (en) 2020-06-16
CY1122166T1 (el) 2020-11-25
PL3067431T3 (pl) 2019-12-31
DK2616550T3 (en) 2016-05-23
ES2751660T3 (es) 2020-04-01
AU2011303467A1 (en) 2013-04-04
US20240280593A1 (en) 2024-08-22
CN107389932A (zh) 2017-11-24
CN103108959B (zh) 2017-06-09
LT3067431T (lt) 2019-11-11

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