CN107389932B - 用于从含纤维蛋白原的样品中分离目标分子或颗粒的方法 - Google Patents

用于从含纤维蛋白原的样品中分离目标分子或颗粒的方法 Download PDF

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Publication number
CN107389932B
CN107389932B CN201710338814.XA CN201710338814A CN107389932B CN 107389932 B CN107389932 B CN 107389932B CN 201710338814 A CN201710338814 A CN 201710338814A CN 107389932 B CN107389932 B CN 107389932B
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fibrinogen
fibrin
sample
particle
fibrin ferment
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CN107389932A (zh
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埃玛·瑞达
尼古拉斯·梅尔莫
帕特里斯·弗兰西斯
弗拉迪米尔·拉扎雷维茨
雅克·施仁泽尔
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Debyofam International Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/14Streptococcus; Staphylococcus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56938Staphylococcus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745Assays involving non-enzymic blood coagulation factors
    • G01N2333/75Fibrin; Fibrinogen
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974Thrombin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
CN201710338814.XA 2010-09-15 2011-09-15 用于从含纤维蛋白原的样品中分离目标分子或颗粒的方法 Active CN107389932B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
CH01478/10 2010-09-15
CH14782010 2010-09-15
CH20412010 2010-12-07
CH02041/10 2010-12-07
CH01207/11 2011-07-20
CH12072011 2011-07-20
CN201180044211.XA CN103108959B (zh) 2010-09-15 2011-09-15 用于从包括成分血的含纤维蛋白原的样品中分离目标分子或颗粒的方法

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CN201180044211.XA Active CN103108959B (zh) 2010-09-15 2011-09-15 用于从包括成分血的含纤维蛋白原的样品中分离目标分子或颗粒的方法

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CY (1) CY1122166T1 (enExample)
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ES (2) ES2751660T3 (enExample)
HR (1) HRP20191785T1 (enExample)
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LT (1) LT3067431T (enExample)
PL (2) PL2616550T3 (enExample)
PT (1) PT3067431T (enExample)
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US9689881B2 (en) 2010-09-15 2017-06-27 Spinomix S.A. Method for separating target molecules or particles from fibrinogen-containing samples including blood components
CN103702674B (zh) 2011-06-27 2018-05-29 爱默蕾大学 血小板裂解物的组合物、用途和制备
EP2979093B1 (en) * 2013-03-29 2019-10-23 Siemens Healthcare Diagnostics Inc. Rare cell concentration
ES2740838T3 (es) * 2014-06-01 2020-02-06 Debiopharm Int Sa Dispositivo de recolección y procesamiento de muestras
US12397302B2 (en) 2015-11-30 2025-08-26 Dh Technologies Development Pte. Ltd. Electromagnetic assemblies for processing fluids
WO2017156375A1 (en) 2016-03-10 2017-09-14 Arthrex, Inc. Systems and methods for preparing a thrombin serum
WO2017156379A2 (en) 2016-03-10 2017-09-14 Arthrex, Inc. Systems and methods for preparing protein enhanced serums
KR20210052389A (ko) 2018-08-27 2021-05-10 리제너론 파마슈티칼스 인코포레이티드 다운스트림 정제에서의 라만 분광법의 사용
JP7298449B2 (ja) * 2019-11-14 2023-06-27 株式会社島津製作所 血液凝固分析装置、及び分注ノズルの洗浄方法

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WO2005021799A2 (en) * 2003-08-15 2005-03-10 University Of South Florida Materials and methods for capture of pathogens and removal of aurintricarboxylic acid from a sample
CN1606447A (zh) * 2001-10-03 2005-04-13 克里斯托弗·J·伍尔弗顿 保存稳定的纤维蛋白原溶液
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EP0325106A1 (de) * 1988-01-05 1989-07-26 Axel Dr. Linhart Verfahren und Test-Kit zur semiquantitativen Bestimmung des Kalziumgehaltes im Blut
EP0587398A1 (en) * 1992-09-09 1994-03-16 Tokuyama Corporation Method of assaying fibrinogen, dry reagent therefor, and process for the preparation thereof
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CN1246069A (zh) * 1997-01-31 2000-03-01 奥姆里克斯生物化学品公司 一种含纤维蛋白原的稳定化混合物
JP2000262499A (ja) * 2000-01-01 2000-09-26 Terumo Corp 採血管
CN1606447A (zh) * 2001-10-03 2005-04-13 克里斯托弗·J·伍尔弗顿 保存稳定的纤维蛋白原溶液
WO2005021799A2 (en) * 2003-08-15 2005-03-10 University Of South Florida Materials and methods for capture of pathogens and removal of aurintricarboxylic acid from a sample
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KR20130107300A (ko) 2013-10-01
KR101948944B1 (ko) 2019-02-15
US20210148940A1 (en) 2021-05-20
AU2011303467B2 (en) 2016-09-15
US20130164737A1 (en) 2013-06-27
CA2811493A1 (en) 2012-03-22
JP5999776B2 (ja) 2016-09-28
AU2011303467C1 (en) 2017-03-09
EP3067431A1 (en) 2016-09-14
EP2616550A2 (en) 2013-07-24
WO2012035508A3 (en) 2012-05-18
PT3067431T (pt) 2019-10-29
ES2571127T3 (es) 2016-05-24
WO2012035508A2 (en) 2012-03-22
EP2616550B1 (en) 2016-02-10
CN103108959A (zh) 2013-05-15
HRP20191785T1 (hr) 2019-12-27
HUE028915T2 (en) 2017-01-30
JP2013538355A (ja) 2013-10-10
AU2016266066A1 (en) 2016-12-22
PL2616550T3 (pl) 2016-08-31
SI3067431T1 (sl) 2019-11-29
HK1247280A1 (zh) 2018-09-21
DK3067431T3 (da) 2019-10-14
WO2012035508A4 (en) 2012-07-19
AU2016266066B2 (en) 2017-12-21
EP3067431B1 (en) 2019-07-24
HUE045771T2 (hu) 2020-01-28
US20170336424A1 (en) 2017-11-23
US9689881B2 (en) 2017-06-27
CA2811493C (en) 2020-06-16
CY1122166T1 (el) 2020-11-25
PL3067431T3 (pl) 2019-12-31
DK2616550T3 (en) 2016-05-23
ES2751660T3 (es) 2020-04-01
AU2011303467A1 (en) 2013-04-04
US20240280593A1 (en) 2024-08-22
CN107389932A (zh) 2017-11-24
CN103108959B (zh) 2017-06-09
LT3067431T (lt) 2019-11-11

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