AU2010315547C1 - Assays for the detection of anti-TNF drugs and autoantibodies - Google Patents

Assays for the detection of anti-TNF drugs and autoantibodies Download PDF

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Publication number
AU2010315547C1
AU2010315547C1 AU2010315547A AU2010315547A AU2010315547C1 AU 2010315547 C1 AU2010315547 C1 AU 2010315547C1 AU 2010315547 A AU2010315547 A AU 2010315547A AU 2010315547 A AU2010315547 A AU 2010315547A AU 2010315547 C1 AU2010315547 C1 AU 2010315547C1
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AU
Australia
Prior art keywords
labeled
tnfa
drug
complex
haca
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Ceased
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AU2010315547A
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English (en)
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AU2010315547B2 (en
AU2010315547A1 (en
Inventor
Linda Ohrmund
Sharat Singh
Shui Long Wang
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Societe des Produits Nestle SA
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Societe des Produits Nestle SA
Nestle SA
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Publication of AU2010315547A1 publication Critical patent/AU2010315547A1/en
Assigned to NESTEC S.A. reassignment NESTEC S.A. Request for Assignment Assignors: PROMETHEUS LABORATORIES INC.
Application granted granted Critical
Publication of AU2010315547B2 publication Critical patent/AU2010315547B2/en
Priority to AU2015202899A priority Critical patent/AU2015202899B2/en
Publication of AU2010315547C1 publication Critical patent/AU2010315547C1/en
Priority to AU2017213584A priority patent/AU2017213584B2/en
Priority to AU2019205009A priority patent/AU2019205009A1/en
Assigned to Société des Produits Nestlé S.A. reassignment Société des Produits Nestlé S.A. Request for Assignment Assignors: NESTEC S.A.
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rehabilitation Therapy (AREA)
  • Physiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
AU2010315547A 2009-10-26 2010-10-26 Assays for the detection of anti-TNF drugs and autoantibodies Ceased AU2010315547C1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2015202899A AU2015202899B2 (en) 2009-10-26 2015-05-28 Assays for the detection of anti-TNF drugs and autoantibodies
AU2017213584A AU2017213584B2 (en) 2009-10-26 2017-08-14 Assays for the detection of anti-TNF drugs and autoantibodies
AU2019205009A AU2019205009A1 (en) 2009-10-26 2019-07-12 Assays for the detection of anti-TNF drugs and autoantibodies

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US25504809P 2009-10-26 2009-10-26
US61/255,048 2009-10-26
US26287709P 2009-11-19 2009-11-19
US61/262,877 2009-11-19
US32463510P 2010-04-15 2010-04-15
US61/324,635 2010-04-15
US34556710P 2010-05-17 2010-05-17
US61/345,567 2010-05-17
US35126910P 2010-06-03 2010-06-03
US61/351,269 2010-06-03
US38967210P 2010-10-04 2010-10-04
US61/389,672 2010-10-04
US39358110P 2010-10-15 2010-10-15
US61/393,581 2010-10-15
PCT/US2010/054125 WO2011056590A1 (en) 2009-10-26 2010-10-26 Assays for the detection of anti-tnf drugs and autoantibodies

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2015202899A Division AU2015202899B2 (en) 2009-10-26 2015-05-28 Assays for the detection of anti-TNF drugs and autoantibodies

Publications (3)

Publication Number Publication Date
AU2010315547A1 AU2010315547A1 (en) 2012-05-10
AU2010315547B2 AU2010315547B2 (en) 2015-03-05
AU2010315547C1 true AU2010315547C1 (en) 2015-06-04

Family

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Family Applications (4)

Application Number Title Priority Date Filing Date
AU2010315547A Ceased AU2010315547C1 (en) 2009-10-26 2010-10-26 Assays for the detection of anti-TNF drugs and autoantibodies
AU2015202899A Ceased AU2015202899B2 (en) 2009-10-26 2015-05-28 Assays for the detection of anti-TNF drugs and autoantibodies
AU2017213584A Ceased AU2017213584B2 (en) 2009-10-26 2017-08-14 Assays for the detection of anti-TNF drugs and autoantibodies
AU2019205009A Abandoned AU2019205009A1 (en) 2009-10-26 2019-07-12 Assays for the detection of anti-TNF drugs and autoantibodies

Family Applications After (3)

Application Number Title Priority Date Filing Date
AU2015202899A Ceased AU2015202899B2 (en) 2009-10-26 2015-05-28 Assays for the detection of anti-TNF drugs and autoantibodies
AU2017213584A Ceased AU2017213584B2 (en) 2009-10-26 2017-08-14 Assays for the detection of anti-TNF drugs and autoantibodies
AU2019205009A Abandoned AU2019205009A1 (en) 2009-10-26 2019-07-12 Assays for the detection of anti-TNF drugs and autoantibodies

Country Status (15)

Country Link
US (5) US8574855B2 (enExample)
EP (1) EP2494352B1 (enExample)
JP (3) JP5697677B2 (enExample)
KR (2) KR101881714B1 (enExample)
CN (2) CN104634955B (enExample)
AU (4) AU2010315547C1 (enExample)
BR (1) BR112012009855A2 (enExample)
CA (2) CA2778454C (enExample)
ES (1) ES2796530T3 (enExample)
IL (2) IL219315B (enExample)
MX (2) MX2012004877A (enExample)
NZ (3) NZ621655A (enExample)
RU (2) RU2571489C2 (enExample)
WO (1) WO2011056590A1 (enExample)
ZA (2) ZA201203717B (enExample)

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