AU2010310565B2 - Dual variable domain immunoglobulins and uses thereof - Google Patents

Dual variable domain immunoglobulins and uses thereof Download PDF

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Publication number
AU2010310565B2
AU2010310565B2 AU2010310565A AU2010310565A AU2010310565B2 AU 2010310565 B2 AU2010310565 B2 AU 2010310565B2 AU 2010310565 A AU2010310565 A AU 2010310565A AU 2010310565 A AU2010310565 A AU 2010310565A AU 2010310565 B2 AU2010310565 B2 AU 2010310565B2
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Australia
Prior art keywords
seq
amino acid
acid sequence
chain amino
binding
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AU2010310565A1 (en
Inventor
Randy L. Bell
Tariq Ghayur
Gillian A. Kingsbury
Yingchun Li
Junjian Liu
Zhihong Liu
Susan E. Morgan-Lappe
Suzanne M. Norvell
Andrew Phillips
Edward B. Reilly
Jieyi Wang
Hua Ying
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AbbVie Inc
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AbbVie Inc
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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