AU2010298768B2 - Separation system and method - Google Patents

Separation system and method Download PDF

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Publication number
AU2010298768B2
AU2010298768B2 AU2010298768A AU2010298768A AU2010298768B2 AU 2010298768 B2 AU2010298768 B2 AU 2010298768B2 AU 2010298768 A AU2010298768 A AU 2010298768A AU 2010298768 A AU2010298768 A AU 2010298768A AU 2010298768 B2 AU2010298768 B2 AU 2010298768B2
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AU
Australia
Prior art keywords
separation
line
column
separation system
separation unit
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AU2010298768A
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English (en)
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AU2010298768A1 (en
Inventor
Daniel G. Go
Adam Kaletski
John Krasnansky
Bin Lin
Lisa Stack
David A. Wareheim
Alan M. Williams
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Global Life Sciences Solutions USA LLC
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Global Life Sciences Solutions USA LLC
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
    • G01N30/465—Flow patterns using more than one column with serial coupling of separation columns with specially adapted interfaces between the columns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B01D15/362—Cation-exchange
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/24—Automatic injection systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
AU2010298768A 2009-09-25 2010-09-20 Separation system and method Active AU2010298768B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/566,701 US9527010B2 (en) 2009-09-25 2009-09-25 Separation system and method
US12/566,701 2009-09-25
PCT/SE2010/051003 WO2011037522A1 (en) 2009-09-25 2010-09-20 Separation system and method

Publications (2)

Publication Number Publication Date
AU2010298768A1 AU2010298768A1 (en) 2012-03-15
AU2010298768B2 true AU2010298768B2 (en) 2015-07-02

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Application Number Title Priority Date Filing Date
AU2010298768A Active AU2010298768B2 (en) 2009-09-25 2010-09-20 Separation system and method

Country Status (7)

Country Link
US (1) US9527010B2 (cg-RX-API-DMAC7.html)
EP (1) EP2480305B1 (cg-RX-API-DMAC7.html)
JP (1) JP5749270B2 (cg-RX-API-DMAC7.html)
CN (1) CN102574026B (cg-RX-API-DMAC7.html)
AU (1) AU2010298768B2 (cg-RX-API-DMAC7.html)
IN (1) IN2012DN01850A (cg-RX-API-DMAC7.html)
WO (1) WO2011037522A1 (cg-RX-API-DMAC7.html)

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Also Published As

Publication number Publication date
AU2010298768A1 (en) 2012-03-15
IN2012DN01850A (cg-RX-API-DMAC7.html) 2015-08-21
CN102574026A (zh) 2012-07-11
EP2480305B1 (en) 2020-10-28
EP2480305A1 (en) 2012-08-01
CN102574026B (zh) 2015-10-07
US20110073548A1 (en) 2011-03-31
US9527010B2 (en) 2016-12-27
WO2011037522A1 (en) 2011-03-31
JP2013506127A (ja) 2013-02-21
JP5749270B2 (ja) 2015-07-15
EP2480305A4 (en) 2014-07-02

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