AU2008360625C1 - Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography - Google Patents

Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography Download PDF

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Publication number
AU2008360625C1
AU2008360625C1 AU2008360625A AU2008360625A AU2008360625C1 AU 2008360625 C1 AU2008360625 C1 AU 2008360625C1 AU 2008360625 A AU2008360625 A AU 2008360625A AU 2008360625 A AU2008360625 A AU 2008360625A AU 2008360625 C1 AU2008360625 C1 AU 2008360625C1
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Prior art keywords
antibody
monoclonal antibody
membrane
antibodies
protein
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AU2008360625A1 (en
AU2008360625B2 (en
Inventor
Jerome Bill Jr.
Arick Brown
Christopher Dowd
Timothy Tully
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Genentech Inc
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Genentech Inc
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Publication of AU2008360625B2 publication Critical patent/AU2008360625B2/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2008360625A 2008-08-14 2008-08-14 Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography Active AU2008360625C1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2008/073179 WO2010019148A1 (en) 2008-08-14 2008-08-14 Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography

Publications (3)

Publication Number Publication Date
AU2008360625A1 AU2008360625A1 (en) 2010-02-18
AU2008360625B2 AU2008360625B2 (en) 2016-05-19
AU2008360625C1 true AU2008360625C1 (en) 2017-01-19

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ID=39899038

Family Applications (1)

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AU2008360625A Active AU2008360625C1 (en) 2008-08-14 2008-08-14 Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography

Country Status (22)

Country Link
US (2) US10927144B2 (https=)
EP (3) EP2321337B2 (https=)
JP (1) JP5666447B2 (https=)
KR (3) KR20180033311A (https=)
CN (1) CN102149724B (https=)
AU (1) AU2008360625C1 (https=)
BR (1) BRPI0823046B1 (https=)
CA (1) CA2731943C (https=)
CY (1) CY1122221T1 (https=)
DK (2) DK2848625T3 (https=)
ES (3) ES2527943T5 (https=)
FI (1) FI3604324T3 (https=)
HR (2) HRP20240472T1 (https=)
HU (2) HUE047316T2 (https=)
IL (2) IL210912B (https=)
LT (2) LT2848625T (https=)
MX (1) MX2011001506A (https=)
PL (2) PL2848625T3 (https=)
PT (2) PT2848625T (https=)
RS (1) RS59232B1 (https=)
SI (2) SI3604324T1 (https=)
WO (1) WO2010019148A1 (https=)

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CN112566930A (zh) * 2018-06-19 2021-03-26 百时美施贵宝公司 使用色谱纯化蛋白质的方法
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Also Published As

Publication number Publication date
WO2010019148A1 (en) 2010-02-18
SI3604324T1 (sl) 2024-06-28
EP2321337A1 (en) 2011-05-18
KR20110067099A (ko) 2011-06-21
ES2749190T3 (es) 2020-03-19
KR101843915B1 (ko) 2018-04-02
EP2848625A1 (en) 2015-03-18
EP2321337B2 (en) 2018-10-10
CY1122221T1 (el) 2020-11-25
HK1210181A1 (en) 2016-04-15
PL3604324T3 (pl) 2024-07-01
ES2978373T3 (es) 2024-09-11
DK2848625T3 (da) 2019-10-07
EP3604324B1 (en) 2024-02-28
ES2527943T3 (es) 2015-02-02
AU2008360625A1 (en) 2010-02-18
US20210284685A1 (en) 2021-09-16
HRP20191848T1 (hr) 2019-12-27
LT3604324T (lt) 2024-05-10
AU2008360625B2 (en) 2016-05-19
PL2848625T3 (pl) 2020-01-31
RS59232B1 (sr) 2019-10-31
DK3604324T3 (da) 2024-04-08
HUE047316T2 (hu) 2020-04-28
US20120122759A1 (en) 2012-05-17
CN102149724B (zh) 2014-04-09
PT2848625T (pt) 2019-10-25
MX2011001506A (es) 2011-03-15
KR20180033311A (ko) 2018-04-02
IL210912B (en) 2019-03-31
IL210912A0 (en) 2011-04-28
JP2011530592A (ja) 2011-12-22
EP2848625B1 (en) 2019-07-31
BRPI0823046B1 (pt) 2021-12-14
EP3604324A1 (en) 2020-02-05
JP5666447B2 (ja) 2015-02-12
ES2527943T5 (es) 2019-03-07
IL262657A (en) 2018-12-31
BRPI0823046A2 (pt) 2015-07-28
EP2321337B1 (en) 2014-10-22
EP2321337B9 (en) 2016-11-30
LT2848625T (lt) 2019-10-10
US10927144B2 (en) 2021-02-23
KR20180137591A (ko) 2018-12-27
KR102196883B1 (ko) 2020-12-30
PT3604324T (pt) 2024-05-10
HRP20240472T1 (hr) 2024-06-21
HUE066562T2 (hu) 2024-08-28
SI2848625T1 (sl) 2019-11-29
CN102149724A (zh) 2011-08-10
IL262657B (en) 2021-03-25
CA2731943A1 (en) 2010-02-18
CA2731943C (en) 2016-11-29
FI3604324T3 (fi) 2024-05-16

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