PT2848625T - Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena. - Google Patents

Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena.

Info

Publication number
PT2848625T
PT2848625T PT141895821T PT14189582T PT2848625T PT 2848625 T PT2848625 T PT 2848625T PT 141895821 T PT141895821 T PT 141895821T PT 14189582 T PT14189582 T PT 14189582T PT 2848625 T PT2848625 T PT 2848625T
Authority
PT
Portugal
Prior art keywords
contaminant
methods
ion exchange
exchange membrane
membrane chromatography
Prior art date
Application number
PT141895821T
Other languages
English (en)
Inventor
Brown Arick
Bill Jerome Jr
Tully Timothy
Dowd Christopher
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39899038&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2848625(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of PT2848625T publication Critical patent/PT2848625T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT141895821T 2008-08-14 2008-08-14 Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena. PT2848625T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US2008/073179 WO2010019148A1 (en) 2008-08-14 2008-08-14 Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography
EP14189582.1A EP2848625B1 (en) 2008-08-14 2008-08-14 Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography

Publications (1)

Publication Number Publication Date
PT2848625T true PT2848625T (pt) 2019-10-25

Family

ID=39899038

Family Applications (2)

Application Number Title Priority Date Filing Date
PT191815315T PT3604324T (pt) 2008-08-14 2008-08-14 Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena
PT141895821T PT2848625T (pt) 2008-08-14 2008-08-14 Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT191815315T PT3604324T (pt) 2008-08-14 2008-08-14 Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena

Country Status (23)

Country Link
US (2) US10927144B2 (pt)
EP (3) EP2848625B1 (pt)
JP (1) JP5666447B2 (pt)
KR (3) KR20180033311A (pt)
CN (1) CN102149724B (pt)
AU (1) AU2008360625C1 (pt)
BR (1) BRPI0823046B1 (pt)
CA (1) CA2731943C (pt)
CY (1) CY1122221T1 (pt)
DK (2) DK3604324T3 (pt)
ES (2) ES2527943T5 (pt)
FI (1) FI3604324T3 (pt)
HK (1) HK1210181A1 (pt)
HR (2) HRP20240472T1 (pt)
HU (1) HUE047316T2 (pt)
IL (2) IL210912B (pt)
LT (2) LT3604324T (pt)
MX (1) MX2011001506A (pt)
PL (1) PL2848625T3 (pt)
PT (2) PT3604324T (pt)
RS (1) RS59232B1 (pt)
SI (1) SI2848625T1 (pt)
WO (1) WO2010019148A1 (pt)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2064314A4 (en) 2006-09-13 2009-12-30 Abbott Lab IMPROVEMENTS TO CELL CULTURE
US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
PT3604324T (pt) 2008-08-14 2024-05-10 Genentech Inc Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena
TW201028433A (en) * 2008-10-20 2010-08-01 Abbott Lab Viral inactivation during purification of antibodies
JP5808249B2 (ja) 2008-10-20 2015-11-10 アッヴィ・インコーポレイテッド プロテインaアフィニティークロマトグラフィーを用いる抗体の単離および精製
MX370828B (es) 2010-05-25 2020-01-08 Genentech Inc Métodos de purificación de polipéptidos.
WO2012030512A1 (en) * 2010-09-03 2012-03-08 Percivia Llc. Flow-through protein purification process
KR20140092227A (ko) * 2010-12-10 2014-07-23 트레이시 톰슨 분리 방법용 조성물
EP2702077A2 (en) 2011-04-27 2014-03-05 AbbVie Inc. Methods for controlling the galactosylation profile of recombinantly-expressed proteins
PL2794635T3 (pl) * 2011-12-22 2019-02-28 F.Hoffmann-La Roche Ag Membranowa chromatografia jonowymienna
US9150645B2 (en) 2012-04-20 2015-10-06 Abbvie, Inc. Cell culture methods to reduce acidic species
WO2013158273A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Methods to modulate c-terminal lysine variant distribution
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
SG11201505203XA (en) * 2013-02-26 2015-08-28 Agency Science Tech & Res Protein purification in the presence of nonionic organic polymers and electropositive surfaces
EP2830651A4 (en) 2013-03-12 2015-09-02 Abbvie Inc HUMAN ANTIBODIES THAT BIND TNF-ALPHA AND PREPARATION METHODS
US10023608B1 (en) 2013-03-13 2018-07-17 Amgen Inc. Protein purification methods to remove impurities
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
JP6163541B2 (ja) * 2013-04-16 2017-07-12 旭化成メディカル株式会社 抗体タンパク質の精製方法
EP3052640A2 (en) 2013-10-04 2016-08-10 AbbVie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
US9546208B2 (en) 2014-01-03 2017-01-17 Bio-Rad Laboratories, Inc. Removal of impurities from protein A eluates
EP3510042B1 (en) * 2016-09-07 2024-05-22 GlaxoSmithKline Intellectual Property Development Limited Methods for purifying antibodies
EP3509729A1 (en) 2016-09-09 2019-07-17 3M Innovative Properties Company Functionalized copolymers and use thereof
US10053368B1 (en) * 2017-09-07 2018-08-21 Chevron U.S.A. Inc. Synthesis of AFX framework type molecular sieves
EP3546475A1 (en) * 2018-03-27 2019-10-02 Sanofi Full flow-through process for purifying recombinant proteins
TW202348297A (zh) * 2018-05-02 2023-12-16 美商里珍納龍藥品有限公司 用於評估生化過濾器的適合性的方法
EP3810650A1 (en) * 2018-06-19 2021-04-28 Bristol-Myers Squibb Company Methods of purifying proteins using chromatography
CN109324143B (zh) * 2018-10-19 2021-10-29 张骐 利用二维液相分离制备抗体类产品相关杂质的方法
CN109806916B (zh) * 2019-03-15 2021-12-21 中科森辉微球技术(苏州)有限公司 高性能阴离子交换介质及其制备方法
KR20220112014A (ko) 2021-02-03 2022-08-10 고인석 십전대보탕을 이용하여 만든 오리목뼈 간식

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
USRE30985E (en) 1978-01-01 1982-06-29 Serum-free cell culture media
US4515893A (en) 1979-04-26 1985-05-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing complement-fixing monoclonal antibody to human T cells
US4347322A (en) 1981-01-12 1982-08-31 Nabisco Brands, Inc. Chromatographic process for enzyme purification
US4560655A (en) 1982-12-16 1985-12-24 Immunex Corporation Serum-free cell culture medium and process for making same
US4657866A (en) 1982-12-21 1987-04-14 Sudhir Kumar Serum-free, synthetic, completely chemically defined tissue culture media
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
DD266710A3 (de) 1983-06-06 1989-04-12 Ve Forschungszentrum Biotechnologie Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase
US4767704A (en) 1983-10-07 1988-08-30 Columbia University In The City Of New York Protein-free culture medium
US4879231A (en) 1984-10-30 1989-11-07 Phillips Petroleum Company Transformation of yeasts of the genus pichia
GB8516415D0 (en) 1985-06-28 1985-07-31 Celltech Ltd Culture of animal cells
US5091178A (en) 1986-02-21 1992-02-25 Oncogen Tumor therapy with biologically active anti-tumor antibodies
US4927762A (en) 1986-04-01 1990-05-22 Cell Enterprises, Inc. Cell culture medium with antioxidant
GB8610600D0 (en) 1986-04-30 1986-06-04 Novo Industri As Transformation of trichoderma
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
US5091313A (en) 1988-08-05 1992-02-25 Tanox Biosystems, Inc. Antigenic epitopes of IgE present on B cell but not basophil surface
US5720937A (en) 1988-01-12 1998-02-24 Genentech, Inc. In vivo tumor detection assay
WO1989012463A1 (en) 1988-06-21 1989-12-28 Genentech, Inc. Method and therapeutic compositions for the treatment of myocardial infarction
EP0435911B1 (en) 1988-09-23 1996-03-13 Cetus Oncology Corporation Cell culture medium for enhanced cell growth, culture longevity and product expression
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
EP0402226A1 (en) 1989-06-06 1990-12-12 Institut National De La Recherche Agronomique Transformation vectors for yeast yarrowia
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
US5122469A (en) 1990-10-03 1992-06-16 Genentech, Inc. Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
DK0602126T3 (da) 1991-08-14 2003-06-16 Genentech Inc Immunoglobulinvarianter til specifikke FC epsilon-receptorer
WO1993011161A1 (en) 1991-11-25 1993-06-10 Enzon, Inc. Multivalent antigen-binding proteins
AU675929B2 (en) 1992-02-06 1997-02-27 Curis, Inc. Biosynthetic binding protein for cancer marker
JPH08500826A (ja) 1992-08-21 1996-01-30 ジェネンテク,インコーポレイテッド Lfa−1仲介疾患を処置する方法
US5736137A (en) 1992-11-13 1998-04-07 Idec Pharmaceuticals Corporation Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
US5595721A (en) 1993-09-16 1997-01-21 Coulter Pharmaceutical, Inc. Radioimmunotherapy of lymphoma using anti-CD20
CA2106612C (en) 1993-09-21 2001-02-06 Diana Pliura Displacement chromatography process
EP0733207B1 (en) 1993-12-10 1997-08-27 Genentech, Inc. Methods for diagnosis of allergy and screening of anti-allergy therapeutics
WO1995019181A1 (en) 1994-01-18 1995-07-20 Genentech, Inc. A METHOD OF TREATMENT OF PARASITIC INFECTION USING IgE ANTAGONISTS
US5702946A (en) 1994-03-03 1997-12-30 Genentech, Inc. Anti-IL-8 monoclonal antibodies for treatment of inflammatory disorders
US5534615A (en) 1994-04-25 1996-07-09 Genentech, Inc. Cardiac hypertrophy factor and uses therefor
IL117645A (en) 1995-03-30 2005-08-31 Genentech Inc Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration
CA2222231A1 (en) 1995-06-07 1996-12-19 Imclone Systems Incorporated Antibody and antibody fragments for inhibiting the growth of tumors
EP0877626B1 (en) 1996-01-23 2002-08-28 Genentech, Inc. Anti-cd18 antibodies for use against stroke
AU1458497A (en) 1996-01-31 1997-08-22 John Stephen Ayers Production of an immunoglobulin enriched fraction from whey protein solutions
US7147851B1 (en) 1996-08-15 2006-12-12 Millennium Pharmaceuticals, Inc. Humanized immunoglobulin reactive with α4β7 integrin
DE69729209T2 (de) 1996-11-27 2005-05-19 Genentech, Inc., South San Francisco Humanisierte anti-koerper gegen cd11a
KR100870353B1 (ko) 1997-04-07 2008-11-25 제넨테크, 인크. 항-vegf 항체
PT981618E (pt) 1997-05-15 2007-11-23 Genentech Inc ''anticorpo anti-apo-2''
US6489447B1 (en) 1998-05-06 2002-12-03 Genentech, Inc. Protein purification
US6946129B1 (en) 1999-06-08 2005-09-20 Seattle Genetics, Inc. Recombinant anti-CD40 antibody and uses thereof
ES2309012T3 (es) 1999-10-29 2008-12-16 Genentech, Inc. Composiciones del anticuerpo anti-psca y a sus procedimientos contra celulas cancerigenas que expresen psca.
US6479636B1 (en) * 2000-04-11 2002-11-12 Honiron Corporation (A Louisiana Corporation) Sugarcane fractioning system
US6633462B2 (en) 2000-07-13 2003-10-14 Koninklijke Philips Electronics N.V. Magnetoresistive angle sensor having several sensing elements
UA83458C2 (uk) 2000-09-18 2008-07-25 Байоджен Айдек Ма Інк. Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
GB2372464B (en) * 2001-02-22 2003-05-14 Vivascience Ltd Method of isolating a charged compound
US7321026B2 (en) 2001-06-27 2008-01-22 Skytech Technology Limited Framework-patched immunoglobulins
CA2476675A1 (en) 2001-10-17 2003-04-24 Human Genome Sciences, Inc. Neutrokine-alpha and neutrokine-alpha splice variant
US20040093621A1 (en) 2001-12-25 2004-05-13 Kyowa Hakko Kogyo Co., Ltd Antibody composition which specifically binds to CD20
AU2003208415B2 (en) 2002-02-14 2009-05-28 Immunomedics, Inc. Anti-CD20 antibodies and fusion proteins thereof and methods of use
AU2003265235A1 (en) * 2002-04-26 2003-12-19 Genetech, Inc. Non-affinity purification of proteins
EP3225625A1 (en) * 2002-09-11 2017-10-04 Chugai Seiyaku Kabushiki Kaisha Protein purification method
NZ568769A (en) 2002-10-17 2010-04-30 Genmab As Human monoclonal antibodies against CD20
KR20070055625A (ko) 2002-12-16 2007-05-30 제넨테크, 인크. 이뮤노글로불린 변이체 및 이들의 용도
CN1802388B (zh) 2003-05-09 2011-01-05 杜克大学 Cd20特异抗体及使用它们的方法
AR044388A1 (es) 2003-05-20 2005-09-07 Applied Molecular Evolution Moleculas de union a cd20
WO2005014618A2 (en) 2003-08-08 2005-02-17 Immunomedics, Inc. Bispecific antibodies for inducing apoptosis of tumor and diseased cells
US8147832B2 (en) 2003-08-14 2012-04-03 Merck Patent Gmbh CD20-binding polypeptide compositions and methods
DK1678208T3 (da) 2003-10-27 2013-07-08 Wyeth Llc Fjernelse af aggregater med høj molekylvægt under anvendelse af hydroxyapatitchromatografi
US8080638B2 (en) 2005-02-10 2011-12-20 Baylor Research Institute Anti-interferon alpha monoclonal antibodies and methods for use
RU2457214C2 (ru) 2005-03-11 2012-07-27 Вайет Способ хроматографии в режиме слабого распределения
JP2009530378A (ja) * 2006-03-20 2009-08-27 メダレックス インコーポレーティッド タンパク質精製法
WO2008057683A2 (en) 2006-10-03 2008-05-15 Novo Nordisk A/S Methods for the purification of polypeptide conjugates
WO2009135656A1 (en) 2008-05-06 2009-11-12 Lonza Biologics Plc. A method for the purification of antibodies using displacement chromatography
PT3604324T (pt) 2008-08-14 2024-05-10 Genentech Inc Métodos para remover um contaminante com a utilização de cromatografia de membrana de permuta iónica de deslocação de proteína indígena
JP5731726B1 (ja) 2014-06-26 2015-06-10 楽天株式会社 情報処理装置、情報処理方法及び情報処理プログラム

Also Published As

Publication number Publication date
EP3604324A1 (en) 2020-02-05
IL210912B (en) 2019-03-31
ES2527943T3 (es) 2015-02-02
HUE047316T2 (hu) 2020-04-28
JP5666447B2 (ja) 2015-02-12
CY1122221T1 (el) 2020-11-25
AU2008360625C1 (en) 2017-01-19
US10927144B2 (en) 2021-02-23
KR101843915B1 (ko) 2018-04-02
AU2008360625A1 (en) 2010-02-18
AU2008360625B2 (en) 2016-05-19
EP3604324B1 (en) 2024-02-28
ES2749190T3 (es) 2020-03-19
US20120122759A1 (en) 2012-05-17
EP2848625A1 (en) 2015-03-18
JP2011530592A (ja) 2011-12-22
HK1210181A1 (en) 2016-04-15
US20210284685A1 (en) 2021-09-16
EP2321337B9 (en) 2016-11-30
DK3604324T3 (da) 2024-04-08
EP2321337B1 (en) 2014-10-22
CA2731943A1 (en) 2010-02-18
DK2848625T3 (da) 2019-10-07
KR20180137591A (ko) 2018-12-27
ES2527943T5 (es) 2019-03-07
EP2321337A1 (en) 2011-05-18
BRPI0823046B1 (pt) 2021-12-14
IL210912A0 (en) 2011-04-28
IL262657A (en) 2018-12-31
IL262657B (en) 2021-03-25
MX2011001506A (es) 2011-03-15
BRPI0823046A2 (pt) 2015-07-28
FI3604324T3 (fi) 2024-05-16
EP2848625B1 (en) 2019-07-31
WO2010019148A1 (en) 2010-02-18
EP2321337B2 (en) 2018-10-10
CN102149724A (zh) 2011-08-10
KR20180033311A (ko) 2018-04-02
LT2848625T (lt) 2019-10-10
SI2848625T1 (sl) 2019-11-29
PL2848625T3 (pl) 2020-01-31
LT3604324T (lt) 2024-05-10
CA2731943C (en) 2016-11-29
RS59232B1 (sr) 2019-10-31
CN102149724B (zh) 2014-04-09
HRP20191848T1 (hr) 2019-12-27
PT3604324T (pt) 2024-05-10
KR102196883B1 (ko) 2020-12-30
HRP20240472T1 (hr) 2024-06-21
KR20110067099A (ko) 2011-06-21

Similar Documents

Publication Publication Date Title
IL262657A (en) Methods for removing a pollutant by copying a natural protein chromatographically to an ion exchange membrane
GB2437519B (en) Method for separation
ZA201002497B (en) Method for making contact lenses
EP2197562A4 (en) LIQUID SEPARATION THROUGH MEMBRANE-BASED STEAM PROCESS
EP2160227A4 (en) chromatographic methods
IL211217A0 (en) Methods for evaluating chromatography column performance
GB0619534D0 (en) Recap alignment clamp
EP2313172A4 (en) BLOCK CONFIGURATION FOR DISTILLATION ON LARGE SCALE MEMBRANE
GB2462516B (en) Methods for operating a filtration system
RS56857B1 (sr) Postupak za odvajanje betaina
IL205107A0 (en) Method for purifying fc-fusion proteins
EP2263105A4 (en) METHOD FOR PERFORMING STRAINED POLARIZATION FILTRATION
EP2170479A4 (en) RECOVERY PROCESS
EP2519536A4 (en) PROTEIN PURIFICATION BY ION EXCHANGE
FR2911793B1 (fr) Procede de separation par chromatographie
EP1987874A4 (en) PROCESS FOR PRODUCING A SEPARATION MEMBRANE BASED ON ZEOLITE
EP2235521A4 (en) METHOD FOR REMOVING AIR FROM A CHROMATOGRAPHIC COLUMN
EP2173770A4 (en) METHOD FOR REMOVING ENDOTOXINS FROM PROTEINS
EP1979927A4 (en) REDEPOSITION TECHNIQUE FOR MEMBRANE FIXATION
EP2213747A4 (en) METHOD FOR PRODUCING A MEMBRANE PROTEIN
PL2257537T3 (pl) Sposób oczyszczania epichlorohydryn
EP2322498A4 (en) PROCESS FOR REMOVING DIBENO FUELS
EP2216408A4 (en) METHOD FOR IMPROVING SALINITY TOLERANCE
EP2005930A4 (de) Verfahren zur faltenentfernung
LT2134498T (lt) Autogeninių apdorojimų būdas