ES2193136T3 - Variantes de inmunoglubina para receptores especificos de fc epsilon. - Google Patents

Variantes de inmunoglubina para receptores especificos de fc epsilon.

Info

Publication number
ES2193136T3
ES2193136T3 ES92918713T ES92918713T ES2193136T3 ES 2193136 T3 ES2193136 T3 ES 2193136T3 ES 92918713 T ES92918713 T ES 92918713T ES 92918713 T ES92918713 T ES 92918713T ES 2193136 T3 ES2193136 T3 ES 2193136T3
Authority
ES
Spain
Prior art keywords
ige
receptor
immunoglubine
epsilon
variants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92918713T
Other languages
English (en)
Inventor
Paula M Jardieu
Leonard G Presta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27114350&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2193136(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ES2193136T3 publication Critical patent/ES2193136T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/526—CH3 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

SE DESCRIBEN DOS CLASES DE POLIPEPTIDOS DERIVADOS DE LA IGE HUMANA. UNA CLASE SE UNE SELECTIVAMENTE AL RECEPTOR DE LA IGE DE ALTA AFINIDAD SOBRE LAS CELULAS DE BASTON Y BASOFILOS, PERO NO AL RECEPTOR DE LA IGE DE BAJA AFINIDAD SOBRE LAS CELULAS B, MONOCITOS, EOSINOFILOS Y PLAQUETAS. LA OTRA CLASE SE UNE AL RECEPTOR DE BAJA AFINIDAD, PERO NO AL RECEPTOR DE ALTA AFINIDAD. LOS POLIPEPTIDOS DE UNION DIFERENCIAL DE ESTA INVENCION SON UTILES EN PROCEDIMIENTOS DE DIAGNOSTICO PARA RECEPTORES DE LA IGE O EN LA TERAPIA DE DESORDENES INTERMEDIADOS POR LA IGE TALES COMO LAS ALERGIAS. TAMBIEN SON UTILES EN LA PREPARACION DE ANTICUERPOS CAPACES DE UNIRSE A REGIONES DE LA IGE QUE PARTICIPAN EN LA UNION DEL RECEPTOR.
ES92918713T 1991-08-14 1992-08-14 Variantes de inmunoglubina para receptores especificos de fc epsilon. Expired - Lifetime ES2193136T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74476891A 1991-08-14 1991-08-14
US87949592A 1992-05-07 1992-05-07

Publications (1)

Publication Number Publication Date
ES2193136T3 true ES2193136T3 (es) 2003-11-01

Family

ID=27114350

Family Applications (2)

Application Number Title Priority Date Filing Date
ES92918713T Expired - Lifetime ES2193136T3 (es) 1991-08-14 1992-08-14 Variantes de inmunoglubina para receptores especificos de fc epsilon.
ES02009009T Expired - Lifetime ES2296839T3 (es) 1991-08-14 1992-08-14 Variantes de inmunoglobulinas para receptores fc-epsilon especificos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES02009009T Expired - Lifetime ES2296839T3 (es) 1991-08-14 1992-08-14 Variantes de inmunoglobulinas para receptores fc-epsilon especificos.

Country Status (11)

Country Link
EP (2) EP1260521B1 (es)
JP (1) JP3457962B2 (es)
AT (1) ATE233813T1 (es)
AU (2) AU2498192A (es)
CA (1) CA2113813C (es)
DE (3) DE69232944T2 (es)
DK (2) DK0602126T3 (es)
ES (2) ES2193136T3 (es)
LU (1) LU91219I2 (es)
NL (1) NL300220I2 (es)
WO (1) WO1993004173A1 (es)

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Also Published As

Publication number Publication date
JP3457962B2 (ja) 2003-10-20
DE69233716D1 (de) 2008-01-03
HK1014542A1 (en) 1999-09-30
CA2113813A1 (en) 1993-03-04
DE69232944T2 (de) 2003-12-24
AU706584C (en) 2003-07-10
NL300220I2 (nl) 2006-08-01
AU7038096A (en) 1997-01-16
NL300220I1 (nl) 2006-04-03
EP1260521A3 (en) 2004-01-02
DE69233716T2 (de) 2008-10-30
ES2296839T3 (es) 2008-05-01
DK0602126T3 (da) 2003-06-16
ATE233813T1 (de) 2003-03-15
WO1993004173A1 (en) 1993-03-04
DE69232944D1 (de) 2003-04-10
EP0602126B1 (en) 2003-03-05
EP1260521A2 (en) 2002-11-27
EP0602126A1 (en) 1994-06-22
AU706584B2 (en) 1999-06-17
DE122006000006I2 (de) 2011-06-16
EP1260521B1 (en) 2007-11-21
CA2113813C (en) 2005-04-12
DE122006000006I1 (de) 2006-04-27
LU91219I2 (fr) 2006-04-03
DK1260521T3 (da) 2008-03-25
JPH06509944A (ja) 1994-11-10
HK1050696A1 (en) 2003-07-04
AU2498192A (en) 1993-03-16

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