AU2006320580B2 - Inhibitors of c-Met and uses thereof - Google Patents
Inhibitors of c-Met and uses thereof Download PDFInfo
- Publication number
- AU2006320580B2 AU2006320580B2 AU2006320580A AU2006320580A AU2006320580B2 AU 2006320580 B2 AU2006320580 B2 AU 2006320580B2 AU 2006320580 A AU2006320580 A AU 2006320580A AU 2006320580 A AU2006320580 A AU 2006320580A AU 2006320580 B2 AU2006320580 B2 AU 2006320580B2
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- Prior art keywords
- aliphatic
- dmso
- compound
- cancer
- optionally substituted
- Prior art date
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Classifications
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
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Applications Claiming Priority (7)
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| US74085905P | 2005-11-30 | 2005-11-30 | |
| US74073705P | 2005-11-30 | 2005-11-30 | |
| US74074105P | 2005-11-30 | 2005-11-30 | |
| US60/740,737 | 2005-11-30 | ||
| US60/740,859 | 2005-11-30 | ||
| US60/740,741 | 2005-11-30 | ||
| PCT/US2006/045847 WO2007064797A2 (en) | 2005-11-30 | 2006-11-30 | Inhibitors of c-met and uses thereof |
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| AU2006320580A1 AU2006320580A1 (en) | 2007-06-07 |
| AU2006320580B2 true AU2006320580B2 (en) | 2011-06-23 |
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| US (2) | US7728017B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1963329B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5144532B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20080080584A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2006320580B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0619252A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2630884A1 (cg-RX-API-DMAC7.html) |
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| NZ (1) | NZ568666A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2007064797A2 (cg-RX-API-DMAC7.html) |
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| WO2005010005A1 (en) * | 2003-07-02 | 2005-02-03 | Sugen, Inc. | Triazolotriazine compounds and uses thereof |
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| US20070191369A1 (en) | 2007-08-16 |
| US7728017B2 (en) | 2010-06-01 |
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| JP2009518296A (ja) | 2009-05-07 |
| MX2008007049A (es) | 2008-10-23 |
| EP1963329B1 (en) | 2013-01-23 |
| WO2007064797A3 (en) | 2007-12-13 |
| WO2007064797A2 (en) | 2007-06-07 |
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