AU2006292377B2 - Use of a DPP-IV inhibitor to reduce hypoglycemic events - Google Patents

Use of a DPP-IV inhibitor to reduce hypoglycemic events Download PDF

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Publication number
AU2006292377B2
AU2006292377B2 AU2006292377A AU2006292377A AU2006292377B2 AU 2006292377 B2 AU2006292377 B2 AU 2006292377B2 AU 2006292377 A AU2006292377 A AU 2006292377A AU 2006292377 A AU2006292377 A AU 2006292377A AU 2006292377 B2 AU2006292377 B2 AU 2006292377B2
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AU
Australia
Prior art keywords
insulin
treatment
dpp
patient
hypoglycemic events
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2006292377A
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English (en)
Other versions
AU2006292377A1 (en
Inventor
Bork Balkan
David Grenville Holmes
Thomas Edward Hughes
Edwin Bernard Villhauer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Emisphere Technologies Inc
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Emisphere Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of AU2006292377A1 publication Critical patent/AU2006292377A1/en
Application granted granted Critical
Publication of AU2006292377B2 publication Critical patent/AU2006292377B2/en
Priority to AU2011202574A priority Critical patent/AU2011202574B2/en
Assigned to EMISPHERE TECHNOLOGIES, INC. reassignment EMISPHERE TECHNOLOGIES, INC. Request for Assignment Assignors: NOVARTIS AG
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2006292377A 2005-09-20 2006-09-18 Use of a DPP-IV inhibitor to reduce hypoglycemic events Ceased AU2006292377B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2011202574A AU2011202574B2 (en) 2005-09-20 2011-06-01 Use of a DPP-IV inhibitor to reduce hypoglycemic events

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US71885605P 2005-09-20 2005-09-20
US60/718,856 2005-09-20
US78675506P 2006-03-28 2006-03-28
US60/786,755 2006-03-28
PCT/US2006/036338 WO2007035665A1 (en) 2005-09-20 2006-09-18 Use of a dpp-iv inhibitor to reduce hypoglycemic events

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2011202574A Division AU2011202574B2 (en) 2005-09-20 2011-06-01 Use of a DPP-IV inhibitor to reduce hypoglycemic events

Publications (2)

Publication Number Publication Date
AU2006292377A1 AU2006292377A1 (en) 2007-03-29
AU2006292377B2 true AU2006292377B2 (en) 2011-03-03

Family

ID=37533536

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006292377A Ceased AU2006292377B2 (en) 2005-09-20 2006-09-18 Use of a DPP-IV inhibitor to reduce hypoglycemic events

Country Status (12)

Country Link
US (2) US8143217B2 (cg-RX-API-DMAC7.html)
EP (1) EP1928499B1 (cg-RX-API-DMAC7.html)
JP (1) JP5072848B2 (cg-RX-API-DMAC7.html)
KR (1) KR101368525B1 (cg-RX-API-DMAC7.html)
AT (1) ATE514435T1 (cg-RX-API-DMAC7.html)
AU (1) AU2006292377B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0616195A2 (cg-RX-API-DMAC7.html)
CA (1) CA2622579C (cg-RX-API-DMAC7.html)
PL (1) PL1928499T3 (cg-RX-API-DMAC7.html)
PT (1) PT1928499E (cg-RX-API-DMAC7.html)
RU (1) RU2440143C2 (cg-RX-API-DMAC7.html)
WO (1) WO2007035665A1 (cg-RX-API-DMAC7.html)

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WO2007035665A1 (en) 2007-03-29
KR101368525B1 (ko) 2014-03-06
CA2622579A1 (en) 2007-03-29
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US8143217B2 (en) 2012-03-27
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CA2622579C (en) 2013-12-31
EP1928499B1 (en) 2011-06-29
AU2006292377A1 (en) 2007-03-29
JP2009508955A (ja) 2009-03-05
EP1928499A1 (en) 2008-06-11
ATE514435T1 (de) 2011-07-15
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US20080300171A1 (en) 2008-12-04
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