RU2440143C2 - Применение ингибитора dpp-iv для снижения приступов гликемии - Google Patents
Применение ингибитора dpp-iv для снижения приступов гликемии Download PDFInfo
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- RU2440143C2 RU2440143C2 RU2008115114/15A RU2008115114A RU2440143C2 RU 2440143 C2 RU2440143 C2 RU 2440143C2 RU 2008115114/15 A RU2008115114/15 A RU 2008115114/15A RU 2008115114 A RU2008115114 A RU 2008115114A RU 2440143 C2 RU2440143 C2 RU 2440143C2
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- RU
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- Prior art keywords
- insulin
- hypoglycemia
- patient
- diabetes
- dpp
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71885605P | 2005-09-20 | 2005-09-20 | |
| US60/718,856 | 2005-09-20 | ||
| US78675506P | 2006-03-28 | 2006-03-28 | |
| US60.786,755 | 2006-03-28 |
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| RU2699030C2 (ru) * | 2015-02-11 | 2019-09-03 | Шанхай Инститьют Оф Матириа Медика, Чайниз Экэдеми Оф Сайэнсиз | Кристаллическая форма а соединения и способ ее получения |
| RU2694527C1 (ru) * | 2018-02-06 | 2019-07-16 | Шмуэль Борис Левит | Комбинация для регенеративной терапии больных сахарным диабетом 1 типа |
| US11116768B2 (en) | 2018-02-06 | 2021-09-14 | Levicure Ltd. | Combination treatment for the regenerative therapy of type 1 diabetes mellitus patients |
Also Published As
| Publication number | Publication date |
|---|---|
| RU2008115114A (ru) | 2009-11-27 |
| US20120149639A1 (en) | 2012-06-14 |
| BRPI0616195A2 (pt) | 2011-06-14 |
| PT1928499E (pt) | 2011-09-09 |
| WO2007035665A1 (en) | 2007-03-29 |
| KR101368525B1 (ko) | 2014-03-06 |
| CA2622579A1 (en) | 2007-03-29 |
| PL1928499T3 (pl) | 2011-11-30 |
| US8143217B2 (en) | 2012-03-27 |
| JP5072848B2 (ja) | 2012-11-14 |
| CA2622579C (en) | 2013-12-31 |
| EP1928499B1 (en) | 2011-06-29 |
| AU2006292377A1 (en) | 2007-03-29 |
| JP2009508955A (ja) | 2009-03-05 |
| EP1928499A1 (en) | 2008-06-11 |
| ATE514435T1 (de) | 2011-07-15 |
| KR20080046198A (ko) | 2008-05-26 |
| US20080300171A1 (en) | 2008-12-04 |
| AU2006292377B2 (en) | 2011-03-03 |
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