AU2006292329A1 - Electrokinetic delivery system and methods therefor - Google Patents

Electrokinetic delivery system and methods therefor Download PDF

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Publication number
AU2006292329A1
AU2006292329A1 AU2006292329A AU2006292329A AU2006292329A1 AU 2006292329 A1 AU2006292329 A1 AU 2006292329A1 AU 2006292329 A AU2006292329 A AU 2006292329A AU 2006292329 A AU2006292329 A AU 2006292329A AU 2006292329 A1 AU2006292329 A1 AU 2006292329A1
Authority
AU
Australia
Prior art keywords
needles
medicament
applicators
applicator
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2006292329A
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English (en)
Inventor
Robert W. Etheredge
Phillip M. Friden
Dennis I. Goldberg
John S. Peterson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transport Pharmaceuticals Inc
Original Assignee
Transport Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transport Pharmaceuticals Inc filed Critical Transport Pharmaceuticals Inc
Publication of AU2006292329A1 publication Critical patent/AU2006292329A1/en
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/20Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/20Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205Vaccinating by means of needles or other puncturing devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Electrotherapy Devices (AREA)
AU2006292329A 2005-09-19 2006-09-19 Electrokinetic delivery system and methods therefor Abandoned AU2006292329A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/228,461 2005-09-19
US11/228,461 US20070066934A1 (en) 2005-09-19 2005-09-19 Electrokinetic delivery system and methods therefor
PCT/US2006/036438 WO2007035710A2 (en) 2005-09-19 2006-09-19 Electrokinetic delivery system and methods therefor

Publications (1)

Publication Number Publication Date
AU2006292329A1 true AU2006292329A1 (en) 2007-03-29

Family

ID=37885188

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006292329A Abandoned AU2006292329A1 (en) 2005-09-19 2006-09-19 Electrokinetic delivery system and methods therefor

Country Status (10)

Country Link
US (1) US20070066934A1 (enExample)
EP (1) EP1926524A4 (enExample)
JP (1) JP2009508595A (enExample)
KR (1) KR20080082603A (enExample)
CN (1) CN101304782A (enExample)
AU (1) AU2006292329A1 (enExample)
BR (1) BRPI0616372A2 (enExample)
CA (1) CA2622818A1 (enExample)
IL (1) IL190241A0 (enExample)
WO (1) WO2007035710A2 (enExample)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1869414A4 (en) * 2005-03-29 2010-07-28 Arkal Medical Inc DEVICES, SYSTEMS, METHODS, AND TOOLS FOR CONTINUOUS GLUCOSE MONITORING
US20070185432A1 (en) * 2005-09-19 2007-08-09 Transport Pharmaceuticals, Inc. Electrokinetic system and method for delivering methotrexate
US20080154107A1 (en) * 2006-12-20 2008-06-26 Jina Arvind N Device, systems, methods and tools for continuous glucose monitoring
US20090131778A1 (en) * 2006-03-28 2009-05-21 Jina Arvind N Devices, systems, methods and tools for continuous glucose monitoring
US20100049021A1 (en) * 2006-03-28 2010-02-25 Jina Arvind N Devices, systems, methods and tools for continuous analyte monitoring
US20070276330A1 (en) * 2006-05-28 2007-11-29 Beck Patricia A Microneedles and methods of fabricating thereof
US20080058726A1 (en) * 2006-08-30 2008-03-06 Arvind Jina Methods and Apparatus Incorporating a Surface Penetration Device
WO2008130463A2 (en) * 2007-02-06 2008-10-30 The Trustees Of The University Of Pennsylvania Multiplexed nanoscale electrochemical sensors for multi-analyte detection
US20080234562A1 (en) * 2007-03-19 2008-09-25 Jina Arvind N Continuous analyte monitor with multi-point self-calibration
US20080312518A1 (en) * 2007-06-14 2008-12-18 Arkal Medical, Inc On-demand analyte monitor and method of use
JP2010529897A (ja) * 2007-06-15 2010-09-02 ニトリツク・バイオ・セラピユーテイクス・インコーポレーテツド 動電学的薬剤配送の電流集中緩和方法とシステム
US20090099427A1 (en) * 2007-10-12 2009-04-16 Arkal Medical, Inc. Microneedle array with diverse needle configurations
WO2009064380A2 (en) 2007-11-09 2009-05-22 California Institute Of Technology Fabrication of anchored carbon nanotube array devices for integrated light collection and energy conversion
US9913806B2 (en) * 2008-06-25 2018-03-13 Fe3 Medical, Inc. Patches and methods for the transdermal delivery of a therapeutically effective amount of iron
EP2381972A2 (en) 2009-01-27 2011-11-02 California Institute Of Technology Drug delivery and substance transfer facilitated by nano-enhanced device having aligned carbon nanotubes protruding from device surface
US8961492B2 (en) 2009-02-12 2015-02-24 Incube Labs, Llc System and method for controlling the iontophoretic delivery of therapeutic agents based on user inhalation
US8190252B2 (en) 2009-02-12 2012-05-29 Incube Labs, Llc Iontophoretic system for transdermal delivery of active agents for therapeutic and medicinal purposes
US8348922B2 (en) * 2009-02-12 2013-01-08 Incube Labs, Llc Method and apparatus for oscillatory iontophoretic transdermal delivery of a therapeutic agent
US9041541B2 (en) * 2010-01-28 2015-05-26 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
US20110105872A1 (en) * 2009-10-30 2011-05-05 Seventh Sense Biosystems, Inc. Systems and methods for application to skin and control of actuation, delivery, and/or perception thereof
US9033898B2 (en) 2010-06-23 2015-05-19 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
US9295417B2 (en) 2011-04-29 2016-03-29 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
US20110172510A1 (en) * 2010-01-13 2011-07-14 Seventh Sense Biosystems, Inc. Rapid delivery and/or withdrawal of fluids
US20110105952A1 (en) * 2009-10-30 2011-05-05 Seventh Sense Biosystems, Inc. Relatively small devices applied to the skin, modular systems, and methods of use thereof
EP2408372B1 (en) 2009-03-02 2019-01-09 Seventh Sense Biosystems, Inc. Devices associated with blood sampling
US8821945B2 (en) 2009-04-25 2014-09-02 Fe3 Medical, Inc. Method for transdermal iontophoretic delivery of chelated agents
US8417330B2 (en) * 2009-06-26 2013-04-09 Incube Labs, Llc Corrosion resistant electrodes for iontophoretic transdermal delivery devices and methods of use
GB2472778B (en) * 2009-08-17 2014-11-19 Barnet Medical Devices Ltd A microneedle roller with a sterilising ultrasound generator and/or ultraviolet light
WO2011044175A2 (en) 2009-10-06 2011-04-14 Incube Labs, Llc Patch and patch assembly for iontophoretic transdermal delivery of active agents for therapeutic and medicinal purposes
WO2011053796A2 (en) * 2009-10-30 2011-05-05 Seventh Sense Biosystems, Inc. Systems and methods for treating, sanitizing, and/or shielding the skin or devices applied to the skin
US8685038B2 (en) 2009-12-07 2014-04-01 Incube Labs, Llc Iontophoretic apparatus and method for marking of the skin
WO2011088211A2 (en) * 2010-01-13 2011-07-21 Seventh Sense Biosystems, Inc. Sampling device interfaces
US8986279B2 (en) 2010-02-10 2015-03-24 Incube Labs, Llc Methods and architecture for power optimization of iontophoretic transdermal drug delivery
WO2011127207A2 (en) 2010-04-07 2011-10-13 California Institute Of Technology Simple method for producing superhydrophobic carbon nanotube array
US10245421B2 (en) 2010-04-28 2019-04-02 Sorrento Therapeutics, Inc. Nanopatterned medical device with enhanced cellular interaction
RU2585138C2 (ru) 2010-04-28 2016-05-27 Кимберли-Кларк Ворлдвайд, Инк. Медицинские устройства для доставки кирнк
PT2563450T (pt) 2010-04-28 2017-08-28 Kimberly Clark Co Dispositivo para entrega de medicação para a artrite reumatóide
CA2796965C (en) 2010-04-28 2019-04-16 Kimberly-Clark Worldwide, Inc. Method for increasing permeability of an epithelial barrier
ES2561824T3 (es) 2010-07-16 2016-03-01 Seventh Sense Biosystems, Inc. Ambiente a baja presión para dispositivos de transferencia de fluidos
US20130158482A1 (en) 2010-07-26 2013-06-20 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
EP2954916A3 (en) * 2010-08-13 2016-04-20 Seventh Sense Biosystems, Inc. Clinical and/or consumer techniques and devices
US20120039809A1 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
ES2565805T3 (es) 2010-11-09 2016-04-07 Seventh Sense Biosystems, Inc. Sistemas e interfaces para el muestreo de sangre
US8609458B2 (en) 2010-12-10 2013-12-17 California Institute Of Technology Method for producing graphene oxide with tunable gap
AU2012230701B2 (en) 2011-03-24 2016-09-29 Incube Labs, Llc System and method for biphasic transdermal iontophoretic delivery of therapeutic agents
WO2012135238A1 (en) 2011-03-29 2012-10-04 California Institute Of Technology Method to increase the capacitance of electrochemical carbon nanotube capacitors by conformal deposition of nanoparticles
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
AU2012249683A1 (en) 2011-04-29 2013-11-14 Seventh Sense Biosystems, Inc. Devices and methods for collection and/or manipulation of blood spots or other bodily fluids
KR102237667B1 (ko) 2011-04-29 2021-04-12 세븐쓰 센스 바이오시스템즈, 인크. 유체들의 전달 및/또는 수용
WO2012154704A2 (en) 2011-05-06 2012-11-15 Incube Labs, Llc System and method for biphasic transdermal iontophoretic delivery of therapeutic agents for the control of addictive cravings
KR20120137096A (ko) * 2011-06-10 2012-12-20 주식회사 한독약품 피부를 통해 조성물을 전달하는 패치 및 그 제조 방법
EP3473296B1 (en) * 2011-06-28 2020-08-05 Inovio Pharmaceuticals, Inc. A minimally invasive dermal electroporation device
CN104039382B (zh) 2011-10-27 2018-01-12 金伯利-克拉克环球有限公司 高粘度生物活性剂的经皮递送
EP3542851B1 (en) 2011-10-27 2021-12-15 Sorrento Therapeutics, Inc. Implantable devices for delivery of bioactive agents
US20170246439A9 (en) 2011-10-27 2017-08-31 Kimberly-Clark Worldwide, Inc. Increased Bioavailability of Transdermally Delivered Agents
WO2013090844A1 (en) 2011-12-14 2013-06-20 California Institute Of Technology Sharp tip carbon nanotube microneedle devices and their fabrication
US9872982B2 (en) * 2012-01-10 2018-01-23 University of Pittsburgh—of the Commonwealth System of Higher Education Electroosmotic convection-enhanced delivery system
US9349543B2 (en) 2012-07-30 2016-05-24 California Institute Of Technology Nano tri-carbon composite systems and manufacture
EP3272387A4 (en) * 2015-03-18 2018-12-12 Toppan Printing Co., Ltd. Drug administration device, and manufacturing method for drug administration device
JP2018086071A (ja) * 2016-11-28 2018-06-07 株式会社リコー 経皮吸収デバイス及び経皮吸収パッチ
EP3338853A1 (en) * 2016-12-23 2018-06-27 Sanofi-Aventis Deutschland GmbH Medicament delivery device
CN107007927A (zh) * 2017-02-21 2017-08-04 中山大学 一种基于电场驱动给药的微针阵列药贴及制备方法
CN107101801B (zh) * 2017-04-18 2019-01-22 华侨大学 一种潮流作用下漂石运移距离现场模拟测试装置
DE102017117784A1 (de) * 2017-08-04 2019-02-07 Lts Lohmann Therapie-Systeme Ag Applikatorsystem enthaltend ein Mikronadelarray aufweisend einen Wirkstoff für die Wundheilung
GB2568287A (en) * 2017-11-10 2019-05-15 Sisaf Ltd Apparatus and methods for the transdermal delivery of active agents
IT201800006526A1 (it) * 2018-06-20 2019-12-20 Microago cavo per la somministrazione transdermica di molecole attive e/o per il campionamento di fluidi biologici e metodo di fabbricazione di tale microago cavo
CN112839700B (zh) * 2018-10-15 2023-05-02 伊英克公司 数字微流控输送装置
AU2018448468A1 (en) * 2018-11-08 2021-04-29 MEDIFORM ITALIA S.r.l. Electric device for the skin allergy test
CN113924142A (zh) * 2019-05-20 2022-01-11 上海必修福企业管理有限公司 电场发生装置及其用途以及使待透皮物质进入目标对象的方法
CN111956951B (zh) * 2019-12-17 2022-09-09 中山大学·深圳 离子导入微针药贴及制备方法
CN113082501A (zh) * 2021-03-10 2021-07-09 苏州纳通生物纳米技术有限公司 一种皮肤疏通装置

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US454088A (en) * 1891-06-16 Automatic feed-water regulator
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US4378806A (en) * 1980-08-12 1983-04-05 Henley Cohn Julian L Gapped resonant microwave apparatus for producing hyperthermia therapy of tumors
US4543088A (en) * 1983-11-07 1985-09-24 American Hospital Supply Corporation Self-sealing subcutaneous injection site
US4837049A (en) * 1986-06-17 1989-06-06 Alfred E. Mann Foundation For Scientific Research Method of making an electrode array
US5163899A (en) * 1987-03-20 1992-11-17 Drug Delivery Systems Inc. Transdermal drug delivery system
EP0429842B1 (en) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5078700A (en) * 1990-03-19 1992-01-07 Becton, Dickinson And Company Liquid crystalline catheter
US5160316A (en) * 1990-09-10 1992-11-03 Henley Julian L Iontophoretic drug delivery apparatus
US5279544A (en) * 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US5331979A (en) * 1992-07-27 1994-07-26 Henley Julian L Iontophoretic cigarette substitute
US5534023A (en) * 1992-12-29 1996-07-09 Henley; Julian L. Fluid filled prosthesis excluding gas-filled beads
US5545143A (en) * 1993-01-21 1996-08-13 T. S. I. Medical Device for subcutaneous medication delivery
US5667487A (en) * 1993-04-07 1997-09-16 Henley; Julian L. Ionosonic drug delivery apparatus
US5415629A (en) * 1993-09-15 1995-05-16 Henley; Julian L. Programmable apparatus for the transdermal delivery of drugs and method
KR100370728B1 (ko) * 1994-10-27 2003-04-07 실리콘 밸리 그룹, 인크. 기판을균일하게코팅하는방법및장치
US6385487B1 (en) * 1996-05-08 2002-05-07 Biophoretic Therapeutic Systems, Llc Methods for electrokinetic delivery of medicaments
US5908401A (en) * 1996-05-08 1999-06-01 The Aps Organization, Llp Method for iontophoretic delivery of antiviral agents
US5676648A (en) * 1996-05-08 1997-10-14 The Aps Organization, Llp Iontophoretic drug delivery apparatus and method for use
DE69719761T2 (de) * 1996-06-18 2003-12-18 Alza Corp., Palo Alto Vorrichtung zur verbesserung der transdermalen verabreichung von medikamenten oder der abnahme von körperflüssigkeiten
EP1005296B8 (en) * 1997-06-05 2005-06-08 Adiana, Inc. Apparatus for tubal occlusion
US5904712A (en) * 1997-06-12 1999-05-18 Axelgaard Manufacturing Co., Ltd. Current-controlling electrode
US6055453A (en) * 1997-08-01 2000-04-25 Genetronics, Inc. Apparatus for addressing needle array electrodes for electroporation therapy
USRE37796E1 (en) 1997-12-16 2002-07-23 Biophoretic Therapeutic Systems, Llc Methods for iontophoretic delivery of antiviral agents
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
JP2000024121A (ja) * 1998-07-08 2000-01-25 Nitto Denko Corp 電極構造体
GB9815819D0 (en) * 1998-07-22 1998-09-16 Secr Defence Transferring materials into cells and a microneedle array
GB9817662D0 (en) * 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
US6148231A (en) * 1998-09-15 2000-11-14 Biophoretic Therapeutic Systems, Llc Iontophoretic drug delivery electrodes and method
US6328735B1 (en) * 1998-10-30 2001-12-11 E.P., Limited Thermal ablation system
US6148232A (en) * 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6597946B2 (en) * 1998-11-09 2003-07-22 Transpharma Ltd. Electronic card for transdermal drug delivery and analyte extraction
WO2000044438A1 (en) * 1999-01-28 2000-08-03 Cyto Pulse Sciences, Inc. Delivery of macromolecules into cells
US6477410B1 (en) * 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
US6792306B2 (en) * 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
DE60018726T2 (de) * 1999-04-16 2006-04-13 Johnson & Johnson Consumer Companies, Inc. Vorrichtung zur iontophoretischen verabreichung von medikamenten mit internen sensoren
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6379324B1 (en) * 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6312612B1 (en) * 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6256533B1 (en) * 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US7133717B2 (en) * 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
US6511463B1 (en) * 1999-11-18 2003-01-28 Jds Uniphase Corporation Methods of fabricating microneedle arrays using sacrificial molds
US6565532B1 (en) * 2000-07-12 2003-05-20 The Procter & Gamble Company Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup
US6656147B1 (en) * 2000-07-17 2003-12-02 Becton, Dickinson And Company Method and delivery device for the transdermal administration of a substance
US6690959B2 (en) * 2000-09-01 2004-02-10 Medtronic, Inc. Skin-mounted electrodes with nano spikes
US6591133B1 (en) * 2000-11-27 2003-07-08 Microlin Llc Apparatus and methods for fluid delivery using electroactive needles and implantable electrochemical delivery devices
US6638246B1 (en) * 2000-11-28 2003-10-28 Scimed Life Systems, Inc. Medical device for delivery of a biologically active material to a lumen
US20020099356A1 (en) * 2001-01-19 2002-07-25 Unger Evan C. Transmembrane transport apparatus and method
US6881203B2 (en) * 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
US6689100B2 (en) * 2001-10-05 2004-02-10 Becton, Dickinson And Company Microdevice and method of delivering or withdrawing a substance through the skin of an animal
US7429258B2 (en) * 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US6780171B2 (en) * 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device
US7115881B2 (en) * 2002-06-04 2006-10-03 Mario Rabinowitz Positioning and motion control by electrons, ions, and neutrals in electric fields
IL152271A (en) * 2002-10-13 2006-04-10 Meir Hefetz Structures of micro needles and manufacturing methods
US6923791B2 (en) * 2003-03-31 2005-08-02 Sterling Medivations, Inc. Infusion device having offset flow path
EP1662987B1 (en) * 2003-09-11 2011-11-09 Theranos, Inc. Medical device for analyte monitoring and drug delivery
US6834206B1 (en) * 2003-12-23 2004-12-21 Sono-Therapy Institute, Inc. Method for the electrical stimulation of human tissue to encourage hair growth
US7315758B2 (en) * 2004-06-03 2008-01-01 Lynntech, Inc. Transdermal delivery of therapeutic agent
US20070276318A1 (en) * 2006-05-26 2007-11-29 Mit, Llp Iontosonic-microneedle applicator apparatus and methods

Also Published As

Publication number Publication date
IL190241A0 (en) 2008-11-03
CA2622818A1 (en) 2007-03-29
JP2009508595A (ja) 2009-03-05
KR20080082603A (ko) 2008-09-11
EP1926524A4 (en) 2009-07-15
WO2007035710A3 (en) 2007-12-06
CN101304782A (zh) 2008-11-12
WO2007035710A2 (en) 2007-03-29
BRPI0616372A2 (pt) 2011-06-21
EP1926524A2 (en) 2008-06-04
US20070066934A1 (en) 2007-03-22

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