AU2006214325B2 - Methods of treating diseases which are mediated by cutaneous lymphocyte antigen positive cells - Google Patents

Methods of treating diseases which are mediated by cutaneous lymphocyte antigen positive cells Download PDF

Info

Publication number
AU2006214325B2
AU2006214325B2 AU2006214325A AU2006214325A AU2006214325B2 AU 2006214325 B2 AU2006214325 B2 AU 2006214325B2 AU 2006214325 A AU2006214325 A AU 2006214325A AU 2006214325 A AU2006214325 A AU 2006214325A AU 2006214325 B2 AU2006214325 B2 AU 2006214325B2
Authority
AU
Australia
Prior art keywords
cells
skin
antagonist
cla
cutaneous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2006214325A
Other languages
English (en)
Other versions
AU2006214325A1 (en
Inventor
Janine Bilsborough
Jane A. Gross
Donald Y. M. Leung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
National Jewish Health
Original Assignee
Zymogenetics Inc
National Jewish Medical and Research Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc, National Jewish Medical and Research Center filed Critical Zymogenetics Inc
Publication of AU2006214325A1 publication Critical patent/AU2006214325A1/en
Application granted granted Critical
Publication of AU2006214325B2 publication Critical patent/AU2006214325B2/en
Priority to AU2012202218A priority Critical patent/AU2012202218B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/006Biological staining of tissues in vivo, e.g. methylene blue or toluidine blue O administered in the buccal area to detect epithelial cancer cells, dyes used for delineating tissues during surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047Cells of the immune system
    • G01N33/505Cells of the immune system involving T-cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869Interleukin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6881Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
AU2006214325A 2005-02-14 2006-02-14 Methods of treating diseases which are mediated by cutaneous lymphocyte antigen positive cells Ceased AU2006214325B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2012202218A AU2012202218B2 (en) 2005-02-14 2012-04-17 Methods Of Treating Diseases Which Are Mediated By Cutaneous Lymphocyte Antigen Positive Cells

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US65311405P 2005-02-14 2005-02-14
US60/653,114 2005-02-14
US71676205P 2005-09-13 2005-09-13
US60/716,762 2005-09-13
US74995205P 2005-12-13 2005-12-13
US60/749,952 2005-12-13
PCT/US2006/005327 WO2006088955A2 (en) 2005-02-14 2006-02-14 Methods of treating diseases which are mediated by cutaneous lymphocyte antigen positive cells

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2012202218A Division AU2012202218B2 (en) 2005-02-14 2012-04-17 Methods Of Treating Diseases Which Are Mediated By Cutaneous Lymphocyte Antigen Positive Cells

Publications (2)

Publication Number Publication Date
AU2006214325A1 AU2006214325A1 (en) 2006-08-24
AU2006214325B2 true AU2006214325B2 (en) 2012-04-05

Family

ID=36685803

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2006214325A Ceased AU2006214325B2 (en) 2005-02-14 2006-02-14 Methods of treating diseases which are mediated by cutaneous lymphocyte antigen positive cells
AU2006214326A Ceased AU2006214326B2 (en) 2005-02-14 2006-02-14 Methods of predicting therapeutic response in atopic dermatitis to IL-31 antagonists

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2006214326A Ceased AU2006214326B2 (en) 2005-02-14 2006-02-14 Methods of predicting therapeutic response in atopic dermatitis to IL-31 antagonists

Country Status (8)

Country Link
US (11) US20060188500A1 (enExample)
EP (2) EP1856150A2 (enExample)
JP (2) JP4927762B2 (enExample)
AU (2) AU2006214325B2 (enExample)
CA (2) CA2595877A1 (enExample)
IL (3) IL184734A (enExample)
MX (2) MX2007009577A (enExample)
WO (2) WO2006088956A2 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE455852T1 (de) 1999-06-02 2010-02-15 Chugai Pharmaceutical Co Ltd Neues hämopoietin rezeptorprotein nr10
AU7445900A (en) 1999-09-27 2001-04-30 Chugai Seiyaku Kabushiki Kaisha Novel hemopoietin receptor protein, nr12
SI2230299T1 (sl) 2002-01-18 2012-07-31 Zymogenetics Inc Nov citokinski zcytor ligand
US10080779B2 (en) 2004-12-15 2018-09-25 Universite D'angers Method for increasing the expression of anti-microbial peptides by keratinocytes comprising administering a composition comprising IL-17, TNF-alpha and OSM
CA2594502A1 (en) * 2005-01-28 2006-08-03 Zymogenetics Inc. Homogeneous preparations of il-31
AU2006214325B2 (en) * 2005-02-14 2012-04-05 National Jewish Medical And Research Center Methods of treating diseases which are mediated by cutaneous lymphocyte antigen positive cells
CA2594490A1 (en) 2005-02-14 2006-08-24 Zymogenetics Inc. Methods of treating skin disorders using an il-31ra antagonist
US20130216542A1 (en) 2005-05-06 2013-08-22 Zymogenetics, Inc. Variable region sequences of il-31 monoclonal antibodies and methods of use
JP5065253B2 (ja) 2005-05-06 2012-10-31 ザイモジェネティクス, インコーポレイテッド Il−31モノクローナル抗体とその使用法
US8101183B2 (en) * 2005-05-06 2012-01-24 Zymogentics, Inc. Variable region sequences of IL-31 monoclonal antibodies
JP2009528264A (ja) 2006-01-10 2009-08-06 ザイモジェネティクス,インコーポレイティド Il−31アンタゴニストを用いて神経組織における疼痛及び炎症を治療する方法
CA2654623C (en) 2006-06-08 2016-07-26 Chugai Seiyaku Kabushiki Kaisha An anti-nr10/il-31ra antibody for use in preventing or treating an inflammatory disease
PL2594586T3 (pl) * 2006-09-01 2015-02-27 Zymogenetics Inc Przeciwciała monoklonalne IL-31 i sposoby ich zastosowania
US7799323B2 (en) * 2007-01-10 2010-09-21 Zymogenetics, Inc. Methods of using IL-31 to treat airway hyper-responsiveness and asthma
MY185647A (en) * 2007-12-05 2021-05-27 Chugai Pharmaceutical Co Ltd Therapeutic agent for pruritus
CA2708251C (en) 2007-12-07 2016-04-12 Zymogenetics, Inc. Humanized antibody molecules specific for il-31
US8790651B2 (en) 2011-07-21 2014-07-29 Zoetis Llc Interleukin-31 monoclonal antibody
JP5650871B1 (ja) * 2013-06-28 2015-01-07 中外製薬株式会社 そう痒を伴う疾患に罹患した患者のil−31アンタゴニストによる治療に対する応答を予測する方法
MA40824A (fr) * 2014-10-22 2017-08-29 Saiba Gmbh Particules de cmv de type virus modifié
HRP20250972T1 (hr) 2015-04-14 2025-10-10 Chugai Seiyaku Kabushiki Kaisha Farmaceutski pripravak za prevenciju i/ili liječenje atopijskog dermatitisa koji sadrži il-31 antagonist kao djelatni sastojak
MA43918A (fr) * 2015-04-14 2018-12-05 Chugai Pharmaceutical Co Ltd Composition pharmaceutique pour la prã‰vention et/ou le traitement de la dermatite atopique contenant comme principe actif un antagoniste de l'il-31
US10060273B2 (en) 2015-04-15 2018-08-28 United Technologies Corporation System and method for manufacture of abrasive coating
US10093731B2 (en) 2017-02-24 2018-10-09 Kindred Biosciences, Inc. Anti-IL31 antibodies for veterinary use
CN112020511B (zh) 2018-03-16 2025-07-04 硕腾服务有限责任公司 用于兽医用途的白介素-31单克隆抗体
MA52011A (fr) 2018-03-16 2021-01-20 Zoetis Services Llc Vaccins peptidiques contre l'interleukine-31
JP2021522241A (ja) * 2018-04-25 2021-08-30 キニクサ ファーマシューティカルズ, リミテッド 抗osmrβ抗体の送達による皮膚疾患又は障害の治療
CN112190708B (zh) * 2019-07-08 2023-09-05 上海交通大学医学院附属瑞金医院 趋化因子受体ccr6抑制剂在预防银屑病复发中的新应用
RU2707181C1 (ru) * 2019-08-15 2019-11-25 федеральное государственное бюджетное образовательное учреждение высшего образования "Башкирский государственный медицинский университет" Министерства здравоохранения Российской Федерации Способ прогнозирования степени тяжести течения пруриго методом определения уровня концентрации триптазы в крови
EP4062933A4 (en) 2019-11-20 2023-12-13 Chugai Seiyaku Kabushiki Kaisha Antibody-containing preparation
KR102392954B1 (ko) * 2020-02-11 2022-05-02 연세대학교 산학협력단 아토피 피부염 동물 모델인 아바타마우스의 제조 방법 및 그의 용도
WO2022049614A1 (ja) 2020-09-01 2022-03-10 中外製薬株式会社 Il-31アンタゴニストを有効成分として含有する、透析そう痒症の予防用及び/又は治療用医薬組成物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003060090A2 (en) * 2002-01-18 2003-07-24 Zymogenetics, Inc. Novel cytokine zcytor17 ligand
US20030215838A1 (en) * 2002-01-18 2003-11-20 Sprecher Cindy A. Cytokine receptor zcytor17 multimers

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792850A (en) * 1996-05-23 1998-08-11 Zymogenetics, Inc. Hematopoietic cytokine receptor
WO2003024484A1 (fr) * 2001-09-14 2003-03-27 Ono Pharmaceutical Co., Ltd. Medicaments pour traiter le prurit
JP2004219390A (ja) * 2002-02-22 2004-08-05 Taisho Pharmaceut Co Ltd アトピー性皮膚炎に対し鎮痒効果を有する薬物の評価方法
KR20040083416A (ko) 2002-02-22 2004-10-01 다이쇼 세이야꾸 가부시끼가이샤 지양제
JP2004107209A (ja) * 2002-09-13 2004-04-08 Nippon Oruganon Kk 掻痒治療薬
JP4503942B2 (ja) * 2003-06-11 2010-07-14 大正製薬株式会社 止痒剤
WO2006000020A1 (en) 2004-06-29 2006-01-05 European Nickel Plc Improved leaching of base metals
CA2594502A1 (en) 2005-01-28 2006-08-03 Zymogenetics Inc. Homogeneous preparations of il-31
AU2006214325B2 (en) * 2005-02-14 2012-04-05 National Jewish Medical And Research Center Methods of treating diseases which are mediated by cutaneous lymphocyte antigen positive cells
CA2594490A1 (en) * 2005-02-14 2006-08-24 Zymogenetics Inc. Methods of treating skin disorders using an il-31ra antagonist
US8101183B2 (en) 2005-05-06 2012-01-24 Zymogentics, Inc. Variable region sequences of IL-31 monoclonal antibodies
JP5065253B2 (ja) 2005-05-06 2012-10-31 ザイモジェネティクス, インコーポレイテッド Il−31モノクローナル抗体とその使用法
WO2007037137A1 (ja) * 2005-09-28 2007-04-05 Konica Minolta Opto, Inc. 射出成形装置
JP2009528264A (ja) * 2006-01-10 2009-08-06 ザイモジェネティクス,インコーポレイティド Il−31アンタゴニストを用いて神経組織における疼痛及び炎症を治療する方法
TW200801513A (en) 2006-06-29 2008-01-01 Fermiscan Australia Pty Ltd Improved process
PL2594586T3 (pl) * 2006-09-01 2015-02-27 Zymogenetics Inc Przeciwciała monoklonalne IL-31 i sposoby ich zastosowania
US7799323B2 (en) 2007-01-10 2010-09-21 Zymogenetics, Inc. Methods of using IL-31 to treat airway hyper-responsiveness and asthma
CA2708251C (en) * 2007-12-07 2016-04-12 Zymogenetics, Inc. Humanized antibody molecules specific for il-31

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003060090A2 (en) * 2002-01-18 2003-07-24 Zymogenetics, Inc. Novel cytokine zcytor17 ligand
US20030215838A1 (en) * 2002-01-18 2003-11-20 Sprecher Cindy A. Cytokine receptor zcytor17 multimers
US20030224487A1 (en) * 2002-01-18 2003-12-04 Sprecher Cindy A. Novel cytokine zcytor17 ligand

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Dillon, S. R. et al (2004) Nature Immunology 5(7): 752-760 *

Also Published As

Publication number Publication date
US20170096484A1 (en) 2017-04-06
JP2008530138A (ja) 2008-08-07
IL184734A (en) 2012-04-30
MX2007009577A (es) 2008-01-30
IL219145A0 (en) 2012-06-28
EP1856150A2 (en) 2007-11-21
US20190040125A1 (en) 2019-02-07
CA2595939C (en) 2014-08-19
US8388964B2 (en) 2013-03-05
IL184776A0 (en) 2007-12-03
CA2595877A1 (en) 2006-08-24
IL184734A0 (en) 2007-12-03
JP4927762B2 (ja) 2012-05-09
US8926957B2 (en) 2015-01-06
CA2595939A1 (en) 2006-08-24
US20130177563A1 (en) 2013-07-11
MX2007009471A (es) 2008-02-15
US20100266600A1 (en) 2010-10-21
US20090280121A1 (en) 2009-11-12
AU2006214325A1 (en) 2006-08-24
US20160024201A1 (en) 2016-01-28
JP2008530137A (ja) 2008-08-07
WO2006088956A2 (en) 2006-08-24
US20060188500A1 (en) 2006-08-24
EP1856539B1 (en) 2015-10-21
US8435745B2 (en) 2013-05-07
US20060188499A1 (en) 2006-08-24
US7723048B2 (en) 2010-05-25
US20130203070A1 (en) 2013-08-08
AU2006214326A1 (en) 2006-08-24
WO2006088955A2 (en) 2006-08-24
IL184776A (en) 2014-06-30
WO2006088956A3 (en) 2007-01-18
AU2006214326B2 (en) 2011-09-29
EP1856539A2 (en) 2007-11-21
US20110212093A1 (en) 2011-09-01
WO2006088955A3 (en) 2006-11-16
US20090092999A1 (en) 2009-04-09

Similar Documents

Publication Publication Date Title
US11312779B2 (en) Methods of treating prurigo nodularis using anti-IL-31RA antibody compositions
US8926957B2 (en) Methods of using IL-31 antagonists in diseases mediated by cutaneous lymphocyte antigen positive T cells
AU2012202218B2 (en) Methods Of Treating Diseases Which Are Mediated By Cutaneous Lymphocyte Antigen Positive Cells

Legal Events

Date Code Title Description
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE COINVENTOR NAME FROM BILLSBOROUGH, JANINE TO BILSBOROUGH, JANINE

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired