ATE455852T1 - Neues hämopoietin rezeptorprotein nr10 - Google Patents

Neues hämopoietin rezeptorprotein nr10

Info

Publication number
ATE455852T1
ATE455852T1 AT00931646T AT00931646T ATE455852T1 AT E455852 T1 ATE455852 T1 AT E455852T1 AT 00931646 T AT00931646 T AT 00931646T AT 00931646 T AT00931646 T AT 00931646T AT E455852 T1 ATE455852 T1 AT E455852T1
Authority
AT
Austria
Prior art keywords
novel
hemopoietin
receptors
hematopoietic
immune system
Prior art date
Application number
AT00931646T
Other languages
English (en)
Inventor
M Maeda
N Yaguchi
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26483716&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE455852(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE455852T1 publication Critical patent/ATE455852T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT00931646T 1999-06-02 2000-06-01 Neues hämopoietin rezeptorprotein nr10 ATE455852T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP15579799 1999-06-02
JP21779799 1999-07-30
PCT/JP2000/003556 WO2000075314A1 (en) 1999-06-02 2000-06-01 Novel hemopoietin receptor protein nr10

Publications (1)

Publication Number Publication Date
ATE455852T1 true ATE455852T1 (de) 2010-02-15

Family

ID=26483716

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00931646T ATE455852T1 (de) 1999-06-02 2000-06-01 Neues hämopoietin rezeptorprotein nr10

Country Status (11)

Country Link
US (6) US7482440B2 (de)
EP (3) EP2325316B8 (de)
JP (7) JP2007111051A (de)
AT (1) ATE455852T1 (de)
AU (1) AU4952400A (de)
CY (1) CY1115582T1 (de)
DE (1) DE60043728D1 (de)
DK (1) DK1188830T3 (de)
ES (1) ES2339843T3 (de)
PT (1) PT1188830E (de)
WO (1) WO2000075314A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2325316B8 (de) * 1999-06-02 2017-04-19 Chugai Seiyaku Kabushiki Kaisha Neues Hämopoietin Receptorprotein, NR10
ES2254224T3 (es) * 1999-09-27 2006-06-16 Chugai Seiyaku Kabushiki Kaisha Nueva proteina del receptor de hematopoyetina, nr12.
US20030096339A1 (en) 2000-06-26 2003-05-22 Sprecher Cindy A. Cytokine receptor zcytor17
EP1325115B1 (de) 2000-06-26 2016-07-27 ZymoGenetics, Inc. Cytokinrezeptor zcytor17
US7317075B2 (en) * 2000-07-20 2008-01-08 Genentech, Inc. PRO21384 polypeptides
WO2002029060A2 (en) * 2000-10-06 2002-04-11 Immunex Corporation Hematopoietin receptors hpr1 and hpr2
WO2002077230A1 (fr) * 2001-03-26 2002-10-03 Chugai Seiyaku Kabushiki Kaisha Variants d'epissage nr10
US9738700B2 (en) 2002-01-18 2017-08-22 Zymogenetics Inc. ZCYTOR17 heterodimeric cytokine receptor
DK1576112T3 (da) 2002-01-18 2012-06-25 Zymogenetics Inc Cytokin-receptor zcytor17-multimerer
ATE536406T1 (de) 2002-01-18 2011-12-15 Zymogenetics Inc Neuartiger zytokin-zcytor17-ligand
AU2003215548A1 (en) * 2002-02-01 2003-09-02 Bayer Healthcare Ag Regulation of human hematopoietin receptor-like protein
SI1485477T1 (sl) * 2002-02-25 2009-10-31 Genentech Inc Novi citokinski receptor GLM-R tipa 1
EP1858924A1 (de) 2005-02-14 2007-11-28 ZymoGenetics, Inc. Verfahren zur behandlung von hauterkrankungen mit einem il-31ra-antagonisten
US20130216542A1 (en) 2005-05-06 2013-08-22 Zymogenetics, Inc. Variable region sequences of il-31 monoclonal antibodies and methods of use
AU2007254715B2 (en) 2005-05-06 2013-08-29 Zymogenetics, Inc. Methods of treating pain and inflammation in neuronal tissue using IL-31 antagonists
EP2301969B1 (de) 2005-05-06 2015-12-23 ZymoGenetics, Inc. IL-31-monoklonale Antikörper und Verfahren zu deren Verwendung
US8101183B2 (en) 2005-05-06 2012-01-24 Zymogentics, Inc. Variable region sequences of IL-31 monoclonal antibodies
CA2647846C (en) 2006-03-31 2016-06-21 Chugai Seiyaku Kabushiki Kaisha Methods for controlling blood pharmacokinetics of antibodies
MY157796A (en) 2006-06-08 2016-07-29 Chugai Pharmaceutical Co Ltd Preventive or remedy for inflammatory disease
KR102339457B1 (ko) 2007-09-26 2021-12-14 추가이 세이야쿠 가부시키가이샤 항체 정상영역 개변체
CN106519025B (zh) 2007-09-26 2021-04-23 中外制药株式会社 利用cdr的氨基酸取代来改变抗体等电点的方法
CN101939025B (zh) 2007-12-05 2015-03-25 中外制药株式会社 搔痒症治疗药
CA2708532C (en) 2007-12-05 2018-06-05 Chugai Seiyaku Kabushiki Kaisha Anti-il31ra antibody and use thereof
ES2660036T3 (es) 2007-12-07 2018-03-20 Zymogenetics, Inc. Moléculas de anticuerpo humanizadas específicas para IL-31
CA2721052C (en) 2008-04-11 2023-02-21 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
KR20110086097A (ko) * 2008-10-23 2011-07-27 알타 디바이씨즈, 인크. 광전지 장치의 얇은 흡수 층
JP5139517B2 (ja) * 2008-12-05 2013-02-06 中外製薬株式会社 抗nr10抗体、およびその利用
KR20160062207A (ko) * 2008-12-05 2016-06-01 추가이 세이야쿠 가부시키가이샤 항nr10 항체 및 그의 이용
JP2010210772A (ja) 2009-03-13 2010-09-24 Dainippon Screen Mfg Co Ltd 液晶表示装置の製造方法
WO2010107109A1 (ja) 2009-03-19 2010-09-23 中外製薬株式会社 抗体定常領域改変体
US9228017B2 (en) 2009-03-19 2016-01-05 Chugai Seiyaku Kabushiki Kaisha Antibody constant region variant
BR112013013354A2 (pt) 2010-11-30 2020-10-06 Chugai Seiyaku Kabushiki Kaisha molécula de ligação ao antígeno capaz de se ligar a uma pluralidade de moléculas de antígeno repetidamente
JP5954916B1 (ja) 2015-04-14 2016-07-20 中外製薬株式会社 Il−31アンタゴニストを有効成分として含有する、アトピー性皮膚炎の予防用及び/又は治療用医薬組成物
WO2016167263A1 (ja) 2015-04-14 2016-10-20 中外製薬株式会社 Il-31アンタゴニストを有効成分として含有する、アトピー性皮膚炎の予防用及び/又は治療用医薬組成物
ES3049513T3 (en) 2018-02-09 2025-12-17 Galderma Holding SA Nemolizumab in the treatment of atopic dermatitis with moderate to severe excoriation
US11236157B2 (en) 2019-01-28 2022-02-01 Galderma Holding SA Treatment of skin lesions and pruritus in prurigo nodularis patients
WO2021100794A1 (ja) 2019-11-20 2021-05-27 中外製薬株式会社 抗体含有製剤
EP4209227A4 (de) 2020-09-01 2024-05-29 Chugai Seiyaku Kabushiki Kaisha Pharmazeutische zusammensetzung zur prävention und/oder behandlung von dialysepruritus mit il-31-antagonisten als wirkstoff
TW202304510A (zh) 2021-04-07 2023-02-01 瑞士商葛德瑪控股公司 結節性癢疹之治療
US20230242652A1 (en) 2021-08-30 2023-08-03 Galderma Holding S.A. Treatments for atopic dermatitis
CN120500352A (zh) 2022-09-02 2025-08-15 高德美控股有限公司 结节性痒疹的治疗

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0239102A3 (de) 1986-03-28 1989-07-12 Tsuji, Kimiyoshi Verfahren zur Herstellung eines Human-Human-Hybridoms
JP2898064B2 (ja) * 1989-08-03 1999-05-31 忠三 岸本 ヒトgp130蛋白質
GB9016440D0 (en) 1990-07-26 1990-09-12 Elopak Systems A laminate
AU8507191A (en) 1990-08-29 1992-03-30 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
WO1993002227A1 (en) 1991-07-15 1993-02-04 Eco-Tec Limited Process and apparatus for treating fluoride containing acid solutions
NZ255101A (en) 1992-07-24 1997-08-22 Cell Genesys Inc A yeast artificial chromosome (yac) vector containing an hprt minigene expressible in murine stem cells and genetically modified rodent therefor
JPH08509612A (ja) 1993-04-26 1996-10-15 ジェンファーム インターナショナル インコーポレイテッド 異種抗体を産生することができるトランスジェニック非ヒト動物
US5783672A (en) * 1994-05-26 1998-07-21 Immunex Corporation Receptor for oncostatin M
EP0822830B1 (de) 1995-04-27 2008-04-02 Amgen Fremont Inc. Aus immunisierten Xenomäusen stammende menschliche Antikörper gegen IL-8
EP0823941A4 (de) 1995-04-28 2001-09-19 Abgenix Inc Menschliche antikörper aus xenomäusen
AUPN481295A0 (en) 1995-08-16 1995-09-07 Medvet Science Pty. Ltd. Agonists of haemopoietic growth factors
AUPN564195A0 (en) * 1995-09-26 1995-10-19 Walter And Eliza Hall Institute Of Medical Research, The A novel haemopoietin receptor and genetic sequences encoding same
ES2334408T3 (es) * 1995-10-23 2010-03-09 Zenyth Operations Pty Ltd Receptor de hematopoyetina y secuencias geneticas que lo codifican.
US6642360B2 (en) * 1997-12-03 2003-11-04 Genentech, Inc. Secreted polypeptides that stimulate release of proteoglycans from cartilage
US6747137B1 (en) * 1998-02-13 2004-06-08 Genome Therapeutics Corporation Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics
EP1088831A4 (de) 1998-06-24 2003-01-02 Chugai Pharmaceutical Co Ltd Hämopoietin-rezeptor proteine
WO2000073451A1 (en) 1999-06-01 2000-12-07 Schering Corporation Mammalian receptor proteins; related reagents and methods
US20030082734A1 (en) 1999-06-01 2003-05-01 Dowling Lynette M. Mammalian receptor proteins; related reagents and methods
EP2325316B8 (de) * 1999-06-02 2017-04-19 Chugai Seiyaku Kabushiki Kaisha Neues Hämopoietin Receptorprotein, NR10
ES2254224T3 (es) 1999-09-27 2006-06-16 Chugai Seiyaku Kabushiki Kaisha Nueva proteina del receptor de hematopoyetina, nr12.
US6756481B2 (en) 2000-05-10 2004-06-29 Schering Corporation IL-23 receptor binding compositions
EP1325115B1 (de) 2000-06-26 2016-07-27 ZymoGenetics, Inc. Cytokinrezeptor zcytor17
WO2002029060A2 (en) 2000-10-06 2002-04-11 Immunex Corporation Hematopoietin receptors hpr1 and hpr2
WO2002077230A1 (fr) 2001-03-26 2002-10-03 Chugai Seiyaku Kabushiki Kaisha Variants d'epissage nr10
DK1576112T3 (da) 2002-01-18 2012-06-25 Zymogenetics Inc Cytokin-receptor zcytor17-multimerer
ATE536406T1 (de) 2002-01-18 2011-12-15 Zymogenetics Inc Neuartiger zytokin-zcytor17-ligand
SI1485477T1 (sl) 2002-02-25 2009-10-31 Genentech Inc Novi citokinski receptor GLM-R tipa 1
JP4567437B2 (ja) 2002-05-01 2010-10-20 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト 抗凝固剤としての新規組織因子標的化されたトロンボモジュリン融合タンパク質
US7579000B2 (en) 2002-05-01 2009-08-25 Bayer Schering Pharma Ag Tissue factor targeted antibodies as anticoagulants
EP1671642A1 (de) 2004-12-15 2006-06-21 Universite D'angers Zusammensetzungen mit (Ant)agonisten von Oncostatin M (OSM), IL-31 und IFN-gamma zur Modulierung der Migration und Funktion von Keratinozyten via einen Rezeptor welcher OSMRbeta als Untereinheit enthält, und entprechende Anwendungen
JP2008528039A (ja) 2005-01-28 2008-07-31 ザイモジェネティクス,インコーポレイティド Il−31の均質調製物
EP1858924A1 (de) * 2005-02-14 2007-11-28 ZymoGenetics, Inc. Verfahren zur behandlung von hauterkrankungen mit einem il-31ra-antagonisten
CA2595939C (en) 2005-02-14 2014-08-19 Zymogenetics Inc. Methods of predicting therpeutic response in atopic dermatitis to il-31 antagonists
AU2007254715B2 (en) 2005-05-06 2013-08-29 Zymogenetics, Inc. Methods of treating pain and inflammation in neuronal tissue using IL-31 antagonists
EP2301969B1 (de) 2005-05-06 2015-12-23 ZymoGenetics, Inc. IL-31-monoklonale Antikörper und Verfahren zu deren Verwendung
MY157796A (en) 2006-06-08 2016-07-29 Chugai Pharmaceutical Co Ltd Preventive or remedy for inflammatory disease

Also Published As

Publication number Publication date
ES2339843T3 (es) 2010-05-26
DE60043728D1 (de) 2010-03-11
US20180002396A1 (en) 2018-01-04
US8017731B2 (en) 2011-09-13
JP2014168462A (ja) 2014-09-18
EP2325316A1 (de) 2011-05-25
US8017738B2 (en) 2011-09-13
WO2000075314A1 (en) 2000-12-14
EP2135953A1 (de) 2009-12-23
EP2325316B1 (de) 2016-09-07
EP1188830B1 (de) 2010-01-20
EP1188830A4 (de) 2005-02-09
US7482440B2 (en) 2009-01-27
US20130115620A1 (en) 2013-05-09
JP2007111051A (ja) 2007-05-10
JP2020036596A (ja) 2020-03-12
PT1188830E (pt) 2010-04-09
JP2012147784A (ja) 2012-08-09
JP2016000042A (ja) 2016-01-07
AU4952400A (en) 2000-12-28
US20030125520A1 (en) 2003-07-03
US8362223B2 (en) 2013-01-29
US20100016552A1 (en) 2010-01-21
DK1188830T3 (da) 2010-04-26
JP5634674B2 (ja) 2014-12-03
EP2135953B1 (de) 2014-04-23
EP1188830A1 (de) 2002-03-20
JP2009137978A (ja) 2009-06-25
JP2018033461A (ja) 2018-03-08
EP2325316B8 (de) 2017-04-19
US20100240096A1 (en) 2010-09-23
CY1115582T1 (el) 2017-01-04
US20100240145A1 (en) 2010-09-23

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