AU2005249380C1 - Kinase modulators and methods of use - Google Patents

Kinase modulators and methods of use Download PDF

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Publication number
AU2005249380C1
AU2005249380C1 AU2005249380A AU2005249380A AU2005249380C1 AU 2005249380 C1 AU2005249380 C1 AU 2005249380C1 AU 2005249380 A AU2005249380 A AU 2005249380A AU 2005249380 A AU2005249380 A AU 2005249380A AU 2005249380 C1 AU2005249380 C1 AU 2005249380C1
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AU
Australia
Prior art keywords
optionally substituted
pyrazolo
piperazin
nmr
esi
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Ceased
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AU2005249380A
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AU2005249380B2 (en
AU2005249380A1 (en
Inventor
Neel K. Anand
Charles M. Blazey
Owen Joseph Bowles
Joerg Bussenius
Lynne Canne Bannen
Diva Sze-Ming Chan
Baili Chen
Erick Wang Co
Simona Costanzo
Steven Charles Defina
Larisa Dubenko
Maurizio Franzini
Ping Huang
Vasu Jammalamadaka
Richard George Khoury
Moon Hwan Kim
Rhett Ronald Klein
Donna Tra Le
Morrison B. Mac
John M. Nuss
Jason Jevious Parks
Kenneth D. Rice
Tsze H. Tsang
Amy Lew Tsuhako
Yong Wang
Wei Xu
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Exelixis Inc
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Exelixis Inc
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Publication of AU2005249380A1 publication Critical patent/AU2005249380A1/en
Publication of AU2005249380B2 publication Critical patent/AU2005249380B2/en
Application granted granted Critical
Publication of AU2005249380C1 publication Critical patent/AU2005249380C1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU2005249380A 2004-04-23 2005-04-22 Kinase modulators and methods of use Ceased AU2005249380C1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56490804P 2004-04-23 2004-04-23
US60/564,908 2004-04-23
PCT/US2005/013860 WO2005117909A2 (en) 2004-04-23 2005-04-22 Kinase modulators and methods of use

Publications (3)

Publication Number Publication Date
AU2005249380A1 AU2005249380A1 (en) 2005-12-15
AU2005249380B2 AU2005249380B2 (en) 2012-05-10
AU2005249380C1 true AU2005249380C1 (en) 2012-09-20

Family

ID=35463331

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005249380A Ceased AU2005249380C1 (en) 2004-04-23 2005-04-22 Kinase modulators and methods of use

Country Status (6)

Country Link
US (1) US8076338B2 (https=)
EP (1) EP1750727A2 (https=)
JP (1) JP5213229B2 (https=)
AU (1) AU2005249380C1 (https=)
CA (1) CA2563699C (https=)
WO (1) WO2005117909A2 (https=)

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