AU2005243488B2 - Vaccine comprising an attenuated pestivirus - Google Patents

Vaccine comprising an attenuated pestivirus Download PDF

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Publication number
AU2005243488B2
AU2005243488B2 AU2005243488A AU2005243488A AU2005243488B2 AU 2005243488 B2 AU2005243488 B2 AU 2005243488B2 AU 2005243488 A AU2005243488 A AU 2005243488A AU 2005243488 A AU2005243488 A AU 2005243488A AU 2005243488 B2 AU2005243488 B2 AU 2005243488B2
Authority
AU
Australia
Prior art keywords
bvdv
term
mutation
virus
coding sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU2005243488A
Other languages
English (en)
Other versions
AU2005243488A1 (en
Inventor
Andreas Ege
Christiane Fetzer
Gregor Meyers
Martina Von Freyburg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Vetmedica GmbH
Original Assignee
Boehringer Ingelheim Vetmedica GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34967522&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2005243488(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Vetmedica GmbH filed Critical Boehringer Ingelheim Vetmedica GmbH
Publication of AU2005243488A1 publication Critical patent/AU2005243488A1/en
Application granted granted Critical
Publication of AU2005243488B2 publication Critical patent/AU2005243488B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/15—Reoviridae, e.g. calf diarrhea virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24361—Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2005243488A 2004-05-19 2005-05-18 Vaccine comprising an attenuated pestivirus Expired AU2005243488B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004025452.4 2004-05-19
DE102004025452A DE102004025452A1 (de) 2004-05-19 2004-05-19 Vakzine enthaltend BVDV
PCT/EP2005/005377 WO2005111201A1 (en) 2004-05-19 2005-05-18 Vaccine comprising an attenuated pestivirus

Publications (2)

Publication Number Publication Date
AU2005243488A1 AU2005243488A1 (en) 2005-11-24
AU2005243488B2 true AU2005243488B2 (en) 2011-07-07

Family

ID=34967522

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005243488A Expired AU2005243488B2 (en) 2004-05-19 2005-05-18 Vaccine comprising an attenuated pestivirus

Country Status (26)

Country Link
EP (1) EP1751276B9 (enExample)
JP (2) JP5006782B2 (enExample)
KR (1) KR100908798B1 (enExample)
CN (2) CN103352030B (enExample)
AR (2) AR049176A1 (enExample)
AT (1) ATE420949T1 (enExample)
AU (1) AU2005243488B2 (enExample)
BR (1) BRPI0510396B1 (enExample)
CA (1) CA2561719C (enExample)
CY (4) CY1109036T1 (enExample)
DE (2) DE102004025452A1 (enExample)
DK (1) DK1751276T5 (enExample)
ES (1) ES2321210T3 (enExample)
FR (3) FR15C0044I2 (enExample)
HU (2) HUS1500033I1 (enExample)
LU (3) LU92749I2 (enExample)
ME (1) ME01119B (enExample)
MX (1) MXPA06013298A (enExample)
NL (3) NL300743I1 (enExample)
NZ (1) NZ552088A (enExample)
PL (1) PL1751276T3 (enExample)
PT (1) PT1751276E (enExample)
RS (1) RS50753B9 (enExample)
SI (1) SI1751276T1 (enExample)
UY (1) UY28905A1 (enExample)
WO (1) WO2005111201A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179473B2 (en) 1998-06-05 2007-02-20 Boehringer Ingelheim Vetmedica Gmbh Attenuated pestiviruses
US7135561B2 (en) 2001-09-06 2006-11-14 Boehringer Ingelheim Vetmedica Gmbh Infectious bovine viral diarrhea virus clone
US20090068223A1 (en) 2005-11-15 2009-03-12 Boehringer Ingelheim Vetmedica, Inc. Combination vaccine comprising an attenuated bovine viral diarrhea virus
CL2007002704A1 (es) 2006-09-22 2008-05-30 Intervet Int Bv Mutante de un pestivirus de una cepa citopatogenica con deleciones en la region codificante de la proteina npro del virus; vacuna que la comprende; y su uso para proteger al ganado vacuno contra la infeccion con un pestivirus tipo silvestre.
CL2008003202A1 (es) 2007-10-29 2009-11-27 Boehringer Ingelheim Vetmedica Inc Composicion inmunogenica que comprende bacterias vivas de mycoplasma bovis atenuada avirulenta.
UY31930A (es) * 2008-06-25 2010-01-29 Boheringer Ingelheim Pharma Kg Pestivirus atenuados recombinantes, en particular a csfv, bvdv o bdv atenuado recombinante
SG10201506597RA (en) 2008-10-31 2015-10-29 Boehringer Ingelheim Vetmed Use Of Various Antigens Including Antigens From Mycoplasma Bovis In Multivalent Vaccine Composition
US8846054B2 (en) 2009-01-09 2014-09-30 Boehringer Ingelheim Vetmedica, Inc. Method of treating pregnant cows and/or heifers
UY32570A (es) 2009-04-24 2010-11-30 Boehringer Ingelheim Vetmed Vacuna viva modificada de mycoplasma bovis mejorada
BR112013006515B1 (pt) 2010-09-21 2020-04-28 Intervet Int Bv vacina de combinação, e, método para a fabricação de uma vacina de combinação
JP6589159B2 (ja) * 2014-04-01 2019-10-16 共立製薬株式会社 新規ネコモルビリウイルス株、不活化ワクチン製剤、並びにネコモルビリウイルス感染症予防方法
ES2757927T3 (es) * 2014-05-23 2020-04-30 Boehringer Ingelheim Vetmedica Gmbh Virus de la peste porcina clásica (VPPC) recombinante que comprende sustituciones en el epítopo TAV de la proteína E2
CN105779499B (zh) * 2016-03-23 2019-11-19 江苏科技大学 重组杆状病毒和其应用及构建该重组杆状病毒的载体
CN107823639B (zh) * 2017-11-10 2020-10-02 齐鲁动物保健品有限公司 牛病毒性腹泻病毒灭活疫苗及其制备方法
CN108707190B (zh) * 2018-04-18 2021-07-13 中国科学院武汉病毒研究所 猪瘟病毒ns5b蛋白保真度突变体及其应用
CN114853912B (zh) * 2022-05-24 2023-06-13 中国农业科学院兰州兽医研究所 一种牛病毒性腹泻病毒e2-e0融合蛋白、制备方法及应用
CN115960847B (zh) * 2023-01-11 2024-06-14 青岛大学 小分子依赖的内含肽自剪接系统在制备减毒活疫苗中的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1013757A2 (en) * 1998-11-10 2000-06-28 Pfizer Products Inc. Attenuated forms of bovine viral diarrhea virus
CA2363493A1 (en) * 2000-11-22 2002-05-22 Xuemei Cao Attenuated forms of bovine viral diarrhea virus
WO2003023041A2 (en) * 2001-09-06 2003-03-20 Boehringer Ingelheim Vetmedica Gmbh Infectious and attenuated bovine viral diarrhea virus clone; methods for their production and use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1104676A1 (en) * 1999-11-30 2001-06-06 Boehringer Ingelheim Vetmedica Gmbh Safe attenuated bovine viral diarrhea viruses for use in pregnant cows

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1013757A2 (en) * 1998-11-10 2000-06-28 Pfizer Products Inc. Attenuated forms of bovine viral diarrhea virus
CA2363493A1 (en) * 2000-11-22 2002-05-22 Xuemei Cao Attenuated forms of bovine viral diarrhea virus
WO2003023041A2 (en) * 2001-09-06 2003-03-20 Boehringer Ingelheim Vetmedica Gmbh Infectious and attenuated bovine viral diarrhea virus clone; methods for their production and use

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MAYER D et al. Vaccine. 2004. 22(3-4): 317-328 *
VAN GENNIP, H.G.P. et al. Vaccine. 2002. 20(11-12): 1544-1556 *

Also Published As

Publication number Publication date
JP5562316B2 (ja) 2014-07-30
FR15C0043I1 (fr) 2015-07-24
WO2005111201A1 (en) 2005-11-24
CA2561719A1 (en) 2005-11-24
CN1989240A (zh) 2007-06-27
CA2561719C (en) 2015-01-27
UY28905A1 (es) 2005-12-30
FR15C0042I1 (fr) 2015-07-24
NL300743I2 (enExample) 2016-01-26
ME01119B (me) 2013-03-20
LU92749I2 (fr) 2015-11-02
AU2005243488A1 (en) 2005-11-24
EP1751276B9 (en) 2020-05-27
DK1751276T3 (da) 2009-05-18
CN103352030B (zh) 2018-08-10
RS50753B9 (sr) 2020-08-31
BRPI0510396A (pt) 2007-11-13
CY2015023I2 (el) 2024-02-16
EP1751276B1 (en) 2009-01-14
MXPA06013298A (es) 2007-05-07
PT1751276E (pt) 2009-02-24
AR104448A2 (es) 2017-07-19
DK1751276T5 (da) 2020-07-20
BRPI0510396B1 (pt) 2020-08-18
AR049176A1 (es) 2006-07-05
DE602005012381D1 (de) 2009-03-05
NL300744I1 (enExample) 2016-01-26
LU92747I2 (fr) 2015-11-02
KR100908798B1 (ko) 2009-07-22
LU92748I2 (fr) 2015-11-02
FR15C0043I2 (fr) 2016-05-27
HUS1500033I1 (hu) 2015-07-28
NL300744I2 (enExample) 2016-01-26
CY2015021I2 (el) 2023-11-15
CY2015022I1 (el) 2020-05-29
CY1109036T1 (el) 2014-07-02
NZ552088A (en) 2009-10-30
FR15C0042I2 (fr) 2018-11-16
CY2015021I1 (el) 2020-05-29
ATE420949T1 (de) 2009-01-15
NL300745I2 (enExample) 2016-01-26
SI1751276T1 (sl) 2009-06-30
JP5006782B2 (ja) 2012-08-22
CN103352030A (zh) 2013-10-16
CN1989240B (zh) 2013-07-31
CY2015022I2 (el) 2024-02-16
JP2012061001A (ja) 2012-03-29
ES2321210T3 (es) 2009-06-03
FR15C0044I2 (fr) 2016-05-27
CY2015023I1 (el) 2020-05-29
RS50753B (sr) 2010-08-31
DE102004025452A1 (de) 2006-01-19
KR20070012862A (ko) 2007-01-29
NL300743I1 (enExample) 2016-01-26
PL1751276T3 (pl) 2009-06-30
EP1751276A1 (en) 2007-02-14
ES2321210T9 (es) 2020-11-04
JP2007537740A (ja) 2007-12-27
NL300745I1 (enExample) 2016-01-26
FR15C0044I1 (fr) 2015-07-24
HUS1500031I1 (hu) 2019-11-28

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired