KR100908798B1 - 약독화 페스티바이러스를 포함하는 백신 - Google Patents

약독화 페스티바이러스를 포함하는 백신 Download PDF

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KR100908798B1
KR100908798B1 KR1020067026800A KR20067026800A KR100908798B1 KR 100908798 B1 KR100908798 B1 KR 100908798B1 KR 1020067026800 A KR1020067026800 A KR 1020067026800A KR 20067026800 A KR20067026800 A KR 20067026800A KR 100908798 B1 KR100908798 B1 KR 100908798B1
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KR20070012862A (ko
Inventor
그레고르 메이어스
안드레아스 에게
크리스티안 페처
프레이부르크 마르티나 폰
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베링거잉겔하임베트메디카게엠베하
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Application filed by 베링거잉겔하임베트메디카게엠베하 filed Critical 베링거잉겔하임베트메디카게엠베하
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/15—Reoviridae, e.g. calf diarrhea virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24361—Methods of inactivation or attenuation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020067026800A 2004-05-19 2005-05-18 약독화 페스티바이러스를 포함하는 백신 Expired - Lifetime KR100908798B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004025452A DE102004025452A1 (de) 2004-05-19 2004-05-19 Vakzine enthaltend BVDV
DE102004025452.4 2004-05-19
PCT/EP2005/005377 WO2005111201A1 (en) 2004-05-19 2005-05-18 Vaccine comprising an attenuated pestivirus

Publications (2)

Publication Number Publication Date
KR20070012862A KR20070012862A (ko) 2007-01-29
KR100908798B1 true KR100908798B1 (ko) 2009-07-22

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KR1020067026800A Expired - Lifetime KR100908798B1 (ko) 2004-05-19 2005-05-18 약독화 페스티바이러스를 포함하는 백신

Country Status (26)

Country Link
EP (1) EP1751276B9 (enExample)
JP (2) JP5006782B2 (enExample)
KR (1) KR100908798B1 (enExample)
CN (2) CN1989240B (enExample)
AR (2) AR049176A1 (enExample)
AT (1) ATE420949T1 (enExample)
AU (1) AU2005243488B2 (enExample)
BR (1) BRPI0510396B1 (enExample)
CA (1) CA2561719C (enExample)
CY (4) CY1109036T1 (enExample)
DE (2) DE102004025452A1 (enExample)
DK (1) DK1751276T5 (enExample)
ES (1) ES2321210T3 (enExample)
FR (3) FR15C0044I2 (enExample)
HU (2) HUS1500031I1 (enExample)
LU (3) LU92748I2 (enExample)
ME (1) ME01119B (enExample)
MX (1) MXPA06013298A (enExample)
NL (3) NL300745I1 (enExample)
NZ (1) NZ552088A (enExample)
PL (1) PL1751276T3 (enExample)
PT (1) PT1751276E (enExample)
RS (1) RS50753B9 (enExample)
SI (1) SI1751276T1 (enExample)
UY (1) UY28905A1 (enExample)
WO (1) WO2005111201A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179473B2 (en) 1998-06-05 2007-02-20 Boehringer Ingelheim Vetmedica Gmbh Attenuated pestiviruses
US7135561B2 (en) 2001-09-06 2006-11-14 Boehringer Ingelheim Vetmedica Gmbh Infectious bovine viral diarrhea virus clone
UY29915A1 (es) * 2005-11-15 2007-06-29 Boehringer Ingelheim Vetmed Vacuna combinada que comprende un virus atenuado de la diarrea viral bovina
WO2008034857A1 (en) 2006-09-22 2008-03-27 Intervet International B.V. Pestivirus mutant for use in a vaccine
AR069087A1 (es) 2007-10-29 2009-12-30 Boehringer Ingelheim Vetmed Cepa bacteriana de m. bovis atenuada avirulenta obtenida por pases, vacuna de micoplasma boris y metodos de uso de la misma
UY31930A (es) * 2008-06-25 2010-01-29 Boheringer Ingelheim Pharma Kg Pestivirus atenuados recombinantes, en particular a csfv, bvdv o bdv atenuado recombinante
EP2362780B1 (en) 2008-10-31 2019-12-25 Boehringer Ingelheim Animal Health USA Inc. Use of various antigens including antigens from mycoplasma bovis in multivalent vaccine composition
US8846054B2 (en) 2009-01-09 2014-09-30 Boehringer Ingelheim Vetmedica, Inc. Method of treating pregnant cows and/or heifers
UY32570A (es) 2009-04-24 2010-11-30 Boehringer Ingelheim Vetmed Vacuna viva modificada de mycoplasma bovis mejorada
ES2606605T3 (es) 2010-09-21 2017-03-24 Intervet International B.V. Vacuna para el BVDV
JP6589159B2 (ja) * 2014-04-01 2019-10-16 共立製薬株式会社 新規ネコモルビリウイルス株、不活化ワクチン製剤、並びにネコモルビリウイルス感染症予防方法
DK3146042T3 (da) * 2014-05-23 2019-09-30 Boehringer Ingelheim Vetmedica Gmbh Rekombinant klassisk svinepestvirus (CSFV) med substitution i E2-proteinets TAV-epitop
CN105779499B (zh) * 2016-03-23 2019-11-19 江苏科技大学 重组杆状病毒和其应用及构建该重组杆状病毒的载体
CN107823639B (zh) * 2017-11-10 2020-10-02 齐鲁动物保健品有限公司 牛病毒性腹泻病毒灭活疫苗及其制备方法
CN108707190B (zh) * 2018-04-18 2021-07-13 中国科学院武汉病毒研究所 猪瘟病毒ns5b蛋白保真度突变体及其应用
CN114853912B (zh) * 2022-05-24 2023-06-13 中国农业科学院兰州兽医研究所 一种牛病毒性腹泻病毒e2-e0融合蛋白、制备方法及应用
CN115960847B (zh) * 2023-01-11 2024-06-14 青岛大学 小分子依赖的内含肽自剪接系统在制备减毒活疫苗中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003023041A2 (en) * 2001-09-06 2003-03-20 Boehringer Ingelheim Vetmedica Gmbh Infectious and attenuated bovine viral diarrhea virus clone; methods for their production and use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6168942B1 (en) * 1998-11-10 2001-01-02 Pfizer Inc. Attenuated forms of bovine viral diarrhea virus
EP1104676A1 (en) * 1999-11-30 2001-06-06 Boehringer Ingelheim Vetmedica Gmbh Safe attenuated bovine viral diarrhea viruses for use in pregnant cows
CA2363493C (en) * 2000-11-22 2006-06-06 Xuemei Cao Attenuated forms of bovine viral diarrhea virus

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003023041A2 (en) * 2001-09-06 2003-03-20 Boehringer Ingelheim Vetmedica Gmbh Infectious and attenuated bovine viral diarrhea virus clone; methods for their production and use

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Publication number Publication date
CA2561719A1 (en) 2005-11-24
FR15C0042I1 (fr) 2015-07-24
AU2005243488A1 (en) 2005-11-24
LU92747I2 (fr) 2015-11-02
CY2015023I2 (el) 2024-02-16
WO2005111201A1 (en) 2005-11-24
FR15C0044I1 (fr) 2015-07-24
BRPI0510396A (pt) 2007-11-13
CY2015022I2 (el) 2024-02-16
FR15C0043I1 (fr) 2015-07-24
NL300745I2 (enExample) 2016-01-26
BRPI0510396B1 (pt) 2020-08-18
FR15C0042I2 (fr) 2018-11-16
JP2012061001A (ja) 2012-03-29
CY2015022I1 (el) 2020-05-29
NZ552088A (en) 2009-10-30
FR15C0043I2 (fr) 2016-05-27
JP5562316B2 (ja) 2014-07-30
FR15C0044I2 (fr) 2016-05-27
SI1751276T1 (sl) 2009-06-30
CN1989240B (zh) 2013-07-31
MXPA06013298A (es) 2007-05-07
CA2561719C (en) 2015-01-27
ES2321210T9 (es) 2020-11-04
RS50753B9 (sr) 2020-08-31
JP2007537740A (ja) 2007-12-27
AR104448A2 (es) 2017-07-19
AU2005243488B2 (en) 2011-07-07
KR20070012862A (ko) 2007-01-29
NL300743I1 (enExample) 2016-01-26
CY2015021I2 (el) 2023-11-15
LU92748I2 (fr) 2015-11-02
CN103352030B (zh) 2018-08-10
DK1751276T3 (da) 2009-05-18
UY28905A1 (es) 2005-12-30
CY1109036T1 (el) 2014-07-02
PT1751276E (pt) 2009-02-24
EP1751276A1 (en) 2007-02-14
EP1751276B9 (en) 2020-05-27
JP5006782B2 (ja) 2012-08-22
LU92749I2 (fr) 2015-11-02
DE102004025452A1 (de) 2006-01-19
CN103352030A (zh) 2013-10-16
CY2015023I1 (el) 2020-05-29
HUS1500031I1 (hu) 2019-11-28
CY2015021I1 (el) 2020-05-29
AR049176A1 (es) 2006-07-05
RS50753B (sr) 2010-08-31
NL300743I2 (enExample) 2016-01-26
ME01119B (me) 2013-03-20
DE602005012381D1 (de) 2009-03-05
EP1751276B1 (en) 2009-01-14
DK1751276T5 (da) 2020-07-20
NL300744I2 (enExample) 2016-01-26
NL300744I1 (enExample) 2016-01-26
PL1751276T3 (pl) 2009-06-30
NL300745I1 (enExample) 2016-01-26
ATE420949T1 (de) 2009-01-15
CN1989240A (zh) 2007-06-27
HUS1500033I1 (hu) 2015-07-28
ES2321210T3 (es) 2009-06-03

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