AU2005216904B2 - Modulation of inflammatory and metastatic processes - Google Patents

Modulation of inflammatory and metastatic processes Download PDF

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Publication number
AU2005216904B2
AU2005216904B2 AU2005216904A AU2005216904A AU2005216904B2 AU 2005216904 B2 AU2005216904 B2 AU 2005216904B2 AU 2005216904 A AU2005216904 A AU 2005216904A AU 2005216904 A AU2005216904 A AU 2005216904A AU 2005216904 B2 AU2005216904 B2 AU 2005216904B2
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AU
Australia
Prior art keywords
groups
substituted
benzimidazol
unsubstituted
amino
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005216904A
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English (en)
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AU2005216904A1 (en
Inventor
Carla C. Heise
Sang H. Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Novartis Vaccines and Diagnostics Inc
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Application filed by Novartis Vaccines and Diagnostics Inc filed Critical Novartis Vaccines and Diagnostics Inc
Publication of AU2005216904A1 publication Critical patent/AU2005216904A1/en
Assigned to NOVARTIS VACCINES AND DIAGNOSTICS, INC. reassignment NOVARTIS VACCINES AND DIAGNOSTICS, INC. Request for Assignment Assignors: CHIRON CORPORATION
Assigned to NOVARTIS VACCINES AND DIAGNOSTICS, INC. reassignment NOVARTIS VACCINES AND DIAGNOSTICS, INC. Alteration of Name(s) of Applicant(s) under S113 Assignors: CHIRON CORPORATION
Application granted granted Critical
Publication of AU2005216904B2 publication Critical patent/AU2005216904B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2005216904A 2004-02-20 2005-02-18 Modulation of inflammatory and metastatic processes Ceased AU2005216904B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US54639504P 2004-02-20 2004-02-20
US60/546,395 2004-02-20
US54710304P 2004-02-23 2004-02-23
US60/547,103 2004-02-23
US55477104P 2004-03-19 2004-03-19
US60/554,771 2004-03-19
PCT/US2005/005316 WO2005082340A2 (en) 2004-02-20 2005-02-18 Modulation of inflammatory and metastatic processes

Publications (2)

Publication Number Publication Date
AU2005216904A1 AU2005216904A1 (en) 2005-09-09
AU2005216904B2 true AU2005216904B2 (en) 2010-11-25

Family

ID=34916329

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005216904A Ceased AU2005216904B2 (en) 2004-02-20 2005-02-18 Modulation of inflammatory and metastatic processes

Country Status (10)

Country Link
US (1) US7875624B2 (https=)
EP (1) EP1718306A2 (https=)
JP (1) JP5019884B2 (https=)
CN (1) CN1960731B (https=)
AU (1) AU2005216904B2 (https=)
BR (1) BRPI0507891A (https=)
CA (1) CA2556872C (https=)
IL (1) IL177574A0 (https=)
RU (1) RU2377988C2 (https=)
WO (1) WO2005082340A2 (https=)

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US8404718B2 (en) 2005-01-21 2013-03-26 Astex Therapeutics Limited Combinations of pyrazole kinase inhibitors
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RU2006133536A (ru) 2008-03-27
WO2005082340A2 (en) 2005-09-09
US7875624B2 (en) 2011-01-25
CA2556872A1 (en) 2005-09-09
BRPI0507891A (pt) 2007-07-24
EP1718306A2 (en) 2006-11-08
AU2005216904A1 (en) 2005-09-09
CN1960731A (zh) 2007-05-09
CN1960731B (zh) 2011-12-07
JP2007523185A (ja) 2007-08-16
US20050239825A1 (en) 2005-10-27
WO2005082340A3 (en) 2006-05-04
IL177574A0 (en) 2006-12-10
JP5019884B2 (ja) 2012-09-05
CA2556872C (en) 2015-05-12

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