EP0868179A4 - New use for losartan - Google Patents
New use for losartanInfo
- Publication number
- EP0868179A4 EP0868179A4 EP96944328A EP96944328A EP0868179A4 EP 0868179 A4 EP0868179 A4 EP 0868179A4 EP 96944328 A EP96944328 A EP 96944328A EP 96944328 A EP96944328 A EP 96944328A EP 0868179 A4 EP0868179 A4 EP 0868179A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- losartan
- new use
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US875795P | 1995-12-12 | 1995-12-12 | |
GB9603376 | 1996-02-16 | ||
GBGB9603376.6A GB9603376D0 (en) | 1996-02-16 | 1996-02-16 | New use for Iosartan |
PCT/US1996/019781 WO1997021436A1 (en) | 1995-12-12 | 1996-12-09 | New use for losartan |
US8757 | 1998-01-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0868179A1 EP0868179A1 (en) | 1998-10-07 |
EP0868179A4 true EP0868179A4 (en) | 2002-01-30 |
Family
ID=26308746
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP96944328A Withdrawn EP0868179A4 (en) | 1995-12-12 | 1996-12-09 | New use for losartan |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0868179A4 (en) |
JP (1) | JP2000501736A (en) |
CA (1) | CA2238975A1 (en) |
WO (1) | WO1997021436A1 (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0855392A3 (en) | 1997-01-22 | 2000-01-05 | Hoechst Aktiengesellschaft | Five-membered heterocycles having biphenylsulphonyl substituents, processes for the preparation thereof, their use as medicaments or diagnostic agent and medicaments containing them |
IT1295405B1 (en) | 1997-09-30 | 1999-05-12 | Merck Sharp & Dohme Italia S P | USE OF AN ANGIOTENSIN II RECEPTORAL ANTAGONIST FOR DRUG PREPARATION TO INCREASE THE SURVIVAL RATE OF |
PL197164B1 (en) * | 1997-10-17 | 2008-03-31 | Ark Therapeutics Ltd | The use of inhibitors of the renin-angiotensin system |
GB2337701A (en) * | 1998-05-26 | 1999-12-01 | United Medical And Dental Schools Of Guys St Thomas Hospitals | Treatment of ischemia with an angiotensin II antagonist |
CN101011390A (en) | 1999-01-26 | 2007-08-08 | 诺瓦提斯公司 | Use of angiotensin II receptor antagonists for treating acute myocardial infarction |
EP1438027A1 (en) * | 2001-10-25 | 2004-07-21 | DepoMed, Inc. | Methods of treatment using a gastric retained losartan dosage |
US7906145B2 (en) | 2002-04-09 | 2011-03-15 | Flamel Technologies | Oral pharmaceutical formulation in the form of aqueous suspension for modified release of active principle(s) |
US7825132B2 (en) | 2002-08-23 | 2010-11-02 | Novartis Vaccines And Diagnostics, Inc. | Inhibition of FGFR3 and treatment of multiple myeloma |
JP2006511616A (en) | 2002-11-13 | 2006-04-06 | カイロン コーポレイション | Methods for treating cancer and related methods |
AU2005216904B2 (en) | 2004-02-20 | 2010-11-25 | Novartis Vaccines And Diagnostics, Inc. | Modulation of inflammatory and metastatic processes |
FR2882260A1 (en) * | 2005-02-21 | 2006-08-25 | Flamel Technologies Sa | MULTIMICROPARTICULAR ORAL PHARMACEUTICAL FORM WITH MODIFIED RELEASE OF ANTAGONISTS OF ANGIOTENSIN II RECEPTORS |
US20090123536A1 (en) * | 2005-02-21 | 2009-05-14 | Flamel Technologies, S.A. | Oral Pharmaceutical Form of Losartan |
FR2884145A1 (en) * | 2005-04-06 | 2006-10-13 | Flamel Technologies Sa | Use of a controlled release losartan oral dosage form, to decrease the inter individual gap of standard deviation of maximum concentration of the losartan, independent of administration of losartan before or after the meals |
KR101319122B1 (en) | 2005-05-13 | 2013-10-23 | 노파르티스 아게 | Methods for treating drug resistant cancer |
US20120095067A1 (en) * | 2009-06-25 | 2012-04-19 | Jin Yang Pharm. Co., Ltd. | Pharmaceutical composition containing carboxylosartan and a production method therefor |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5565485A (en) * | 1993-03-19 | 1996-10-15 | Merck & Co., Inc. | Biphenyl compounds useful or endothelin antagonists |
US5538991A (en) * | 1994-09-14 | 1996-07-23 | Merck & Co., Inc. | Endothelin antagonists bearing 5-membered heterocyclic amides |
-
1996
- 1996-12-09 EP EP96944328A patent/EP0868179A4/en not_active Withdrawn
- 1996-12-09 WO PCT/US1996/019781 patent/WO1997021436A1/en not_active Application Discontinuation
- 1996-12-09 JP JP9522199A patent/JP2000501736A/en active Pending
- 1996-12-09 CA CA002238975A patent/CA2238975A1/en not_active Abandoned
Non-Patent Citations (9)
Title |
---|
CAPASSO ET AL.: "Efficacy of ACE inhibition and AT1 receptor blockade on cardiac pump performance after myocardial infarction in rats", J. CARDIOVASC. PHARMACOL., vol. 23, 1994, pages 584 - 593, XP001033935 * |
FLEETWOOD G ET AL: "INVOLVEMENT OF THE RENIN ANGIOTENSIN SYSTEM IN ISCHEMIC DAMAGE AND REPERFUSION ARRHYTHMIAS IN THE ISOLATED PERFUSED RAT HEART", JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, vol. 17, no. 3, 1991, pages 351 - 356, XP001029360, ISSN: 0160-2446 * |
IZUMI HISAKO ET AL: "Effects of BIBR-277, an angiotensin II type 1 receptor antagonist, on stunned myocardium in dogs.", CORONARY ARTERY DISEASE, vol. 7, no. 10, 1996, pages 775 - 779, XP001033778, ISSN: 0954-6928 * |
SCHIEFFER ET AL.: "Comparative effects of chronic ACE inhibition and AII type1 receptor blockade on cardiac remodeling after myocardial infarction in the rat", CIRCULATION, vol. 89, 1994, pages 2273 - 2282, XP001033870 * |
See also references of WO9721436A1 * |
WERRMANN JEFFREY G ET AL: "Comparison of effects of angiotensin-converting enzyme inhibition with those of angiotensin II receptor antagonism on functional and metabolic recovery in postischemic working rat heart as studied by (31P) nuclear magnetic resonance.", JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, vol. 24, no. 4, 1994, pages 573 - 586, XP001029379, ISSN: 0160-2446 * |
YOSHIYAMA ET AL.: "cardioprotective effect of the AII type 1 receptor antagonisr TCV-116 on ischemia-reperfusion injury", AMERICAN HEART JOURNAL, vol. 128, 1994, pages 1-6, XP001029664 * |
YOSHIYAMA MINORU ET AL: "Protective effect of pretreatment with angiotensin II type I receptor antagonist on the ischemia-reperfused myocardium.", CIRCULATION, vol. 88, no. 4 PART 2, 1993, 66th Scientific Sessions of the American Heart Association;Atlanta, Georgia, USA; November 8-11, 1993, pages I474, XP001029391, ISSN: 0009-7322 * |
ZWEIER JAY L ET AL: "Angiotensin II receptor blockade decreases neutrophil-mediated injury in the postischemic heart.", FASEB JOURNAL, vol. 9, no. 4, 1995, Experimental Biology 95, Part II;Atlanta, Georgia, USA; April 9-13, 1995, pages A844, XP001029375, ISSN: 0892-6638 * |
Also Published As
Publication number | Publication date |
---|---|
AU1416497A (en) | 1997-07-03 |
EP0868179A1 (en) | 1998-10-07 |
AU704841B2 (en) | 1999-05-06 |
CA2238975A1 (en) | 1997-06-19 |
WO1997021436A1 (en) | 1997-06-19 |
JP2000501736A (en) | 2000-02-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PL324869A1 (en) | Benzimidazole compounds | |
HU9600255D0 (en) | New compounds | |
EP0868179A4 (en) | New use for losartan | |
GB9500691D0 (en) | Compounds | |
GB9504910D0 (en) | Compounds | |
GB9505538D0 (en) | New compounds | |
GB9508637D0 (en) | New use | |
GB2308509B (en) | Services-connections for trailer-vehicles | |
GB9504948D0 (en) | Compounds | |
GB2308393B (en) | Windshelter for sun-bathing | |
GB9502540D0 (en) | Compounds | |
GB2298174B (en) | Services-connections for trailer-vehicles | |
ZA963484B (en) | New use | |
GB9516136D0 (en) | New Use | |
GB9505071D0 (en) | Use | |
GB9519905D0 (en) | Use | |
GB9520121D0 (en) | Use | |
GB9520119D0 (en) | Use | |
GB9519915D0 (en) | Use | |
GB9503206D0 (en) | Novel use | |
GB9515843D0 (en) | Benzimidazole compounds | |
GB9506703D0 (en) | Compounds | |
GB9526630D0 (en) | Compounds | |
GB9518487D0 (en) | Compounds | |
GB9506168D0 (en) | Compounds |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19980713 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20011217 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
|
17Q | First examination report despatched |
Effective date: 20020405 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20040422 |