AU2004311545B2 - Methods for eliminating mannosylphosphorylation of glycans in the production of glycoproteins - Google Patents

Methods for eliminating mannosylphosphorylation of glycans in the production of glycoproteins Download PDF

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Publication number
AU2004311545B2
AU2004311545B2 AU2004311545A AU2004311545A AU2004311545B2 AU 2004311545 B2 AU2004311545 B2 AU 2004311545B2 AU 2004311545 A AU2004311545 A AU 2004311545A AU 2004311545 A AU2004311545 A AU 2004311545A AU 2004311545 B2 AU2004311545 B2 AU 2004311545B2
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Prior art keywords
pichia
glycoproteins
yeast
genes
pastoris
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Ceased
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AU2004311545A
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AU2004311545A1 (en
Inventor
Piotr Bobrowicz
Terrance Stadheim
Stefan Wildt
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GlycoFi Inc
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GlycoFi Inc
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Assigned to GLYCOFI, INC. reassignment GLYCOFI, INC. Request for Assignment Assignors: BOBROWICZ, PIOTR, GLYCOFI, INC., STADHEIM, TERRANCE, WILDT, STEFAN
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Publication of AU2004311545B2 publication Critical patent/AU2004311545B2/en
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Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
AU2004311545A 2003-12-24 2004-12-22 Methods for eliminating mannosylphosphorylation of glycans in the production of glycoproteins Ceased AU2004311545B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2008249203A AU2008249203B2 (en) 2003-12-24 2008-11-25 Methods for Eliminating Mannosylphosphorylation of Glycans in the Production of Glycoproteins

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53246103P 2003-12-24 2003-12-24
US60/532,461 2003-12-24
PCT/IB2004/052887 WO2005065019A2 (en) 2003-12-24 2004-12-22 Methods for eliminating mannosylphosphorylation of glycans in the production of glycoproteins

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2008249203A Division AU2008249203B2 (en) 2003-12-24 2008-11-25 Methods for Eliminating Mannosylphosphorylation of Glycans in the Production of Glycoproteins

Publications (2)

Publication Number Publication Date
AU2004311545A1 AU2004311545A1 (en) 2005-07-21
AU2004311545B2 true AU2004311545B2 (en) 2008-11-06

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ID=34748799

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2004311545A Ceased AU2004311545B2 (en) 2003-12-24 2004-12-22 Methods for eliminating mannosylphosphorylation of glycans in the production of glycoproteins
AU2008249203A Ceased AU2008249203B2 (en) 2003-12-24 2008-11-25 Methods for Eliminating Mannosylphosphorylation of Glycans in the Production of Glycoproteins

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2008249203A Ceased AU2008249203B2 (en) 2003-12-24 2008-11-25 Methods for Eliminating Mannosylphosphorylation of Glycans in the Production of Glycoproteins

Country Status (7)

Country Link
US (1) US7259007B2 (cg-RX-API-DMAC7.html)
EP (2) EP1696864B1 (cg-RX-API-DMAC7.html)
JP (1) JP4861830B2 (cg-RX-API-DMAC7.html)
AU (2) AU2004311545B2 (cg-RX-API-DMAC7.html)
CA (1) CA2551484C (cg-RX-API-DMAC7.html)
ES (1) ES2528739T3 (cg-RX-API-DMAC7.html)
WO (1) WO2005065019A2 (cg-RX-API-DMAC7.html)

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US20060029604A1 (en) * 2000-06-28 2006-02-09 Gerngross Tillman U Immunoglobulins comprising predominantly a GlcNAc2Man3GlcNAc2 glycoform
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JP5967861B2 (ja) 2007-04-03 2016-08-10 オキシレイン ユーケー リミテッド 分子のグリコシル化
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Also Published As

Publication number Publication date
EP1696864A4 (en) 2008-03-26
ES2528739T3 (es) 2015-02-12
CA2551484C (en) 2015-03-31
WO2005065019A2 (en) 2005-07-21
JP2007530014A (ja) 2007-11-01
CA2551484A1 (en) 2005-07-21
WO2005065019A3 (en) 2007-01-25
EP1696864B1 (en) 2014-11-12
AU2004311545A1 (en) 2005-07-21
US7259007B2 (en) 2007-08-21
EP1696864A2 (en) 2006-09-06
EP2341128A1 (en) 2011-07-06
AU2008249203B2 (en) 2012-08-16
JP4861830B2 (ja) 2012-01-25
US20060160179A1 (en) 2006-07-20
AU2008249203A1 (en) 2008-12-18

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