AU2004264726A1 - Dosing schedule for erbB2 anticancer agents - Google Patents
Dosing schedule for erbB2 anticancer agents Download PDFInfo
- Publication number
- AU2004264726A1 AU2004264726A1 AU2004264726A AU2004264726A AU2004264726A1 AU 2004264726 A1 AU2004264726 A1 AU 2004264726A1 AU 2004264726 A AU2004264726 A AU 2004264726A AU 2004264726 A AU2004264726 A AU 2004264726A AU 2004264726 A1 AU2004264726 A1 AU 2004264726A1
- Authority
- AU
- Australia
- Prior art keywords
- methyl
- inhibitor
- yloxy
- pyridin
- quinazolin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US49591903P | 2003-08-18 | 2003-08-18 | |
| US60/495,919 | 2003-08-18 | ||
| PCT/IB2004/002580 WO2005016347A1 (en) | 2003-08-18 | 2004-08-06 | Dosing schedule for erbb2 anticancer agents |
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| AU2004264726A1 true AU2004264726A1 (en) | 2005-02-24 |
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| JP (1) | JP2007502807A (enExample) |
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| CN (1) | CN1838959A (enExample) |
| AR (1) | AR045268A1 (enExample) |
| AU (1) | AU2004264726A1 (enExample) |
| BR (1) | BRPI0413745A (enExample) |
| CA (1) | CA2536140A1 (enExample) |
| CO (1) | CO5670356A2 (enExample) |
| IL (1) | IL173127A0 (enExample) |
| MX (1) | MXPA06001989A (enExample) |
| NO (1) | NO20061252L (enExample) |
| RU (1) | RU2328287C2 (enExample) |
| SG (1) | SG135193A1 (enExample) |
| TW (1) | TW200522966A (enExample) |
| WO (1) | WO2005016347A1 (enExample) |
| ZA (1) | ZA200600517B (enExample) |
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| CN101717410B (zh) | 2002-02-01 | 2015-04-29 | 阿里亚德医药股份有限公司 | 含磷化合物及其应用 |
| TWI229650B (en) * | 2002-11-19 | 2005-03-21 | Sharp Kk | Substrate accommodating tray |
| NZ545459A (en) * | 2003-08-14 | 2009-12-24 | Array Biopharma Inc | Quinazoline analogs as receptor tyrosine kinase inhibitors |
| US7501427B2 (en) * | 2003-08-14 | 2009-03-10 | Array Biopharma, Inc. | Quinazoline analogs as receptor tyrosine kinase inhibitors |
| PL1667992T3 (pl) | 2003-09-19 | 2007-05-31 | Astrazeneca Ab | Pochodne chinazoliny |
| RS52119B (sr) | 2004-05-06 | 2012-08-31 | Warner-Lambert Company Llc | 4-fenilamino-hinazolin-6-il-amidi |
| GB0427131D0 (en) * | 2004-12-10 | 2005-01-12 | Glaxosmithkline Biolog Sa | Novel combination |
| JP2008542354A (ja) * | 2005-06-03 | 2008-11-27 | ファイザー・プロダクツ・インク | 癌治療におけるｅｒｂＢ２阻害剤と他の治療薬の併用 |
| JP5235662B2 (ja) * | 2005-06-16 | 2013-07-10 | ミリアド ジェネティクス， インコーポレイテッド | 薬学的組成物およびその使用 |
| US20080219977A1 (en) * | 2005-07-27 | 2008-09-11 | Isaiah Josh Fidler | Combinations Comprising Gemcitabine and Tyrosine Kinase Inhibitors for the Treatment of Pancreatic Cancer |
| US8945573B2 (en) | 2005-09-08 | 2015-02-03 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Targeted identification of immunogenic peptides |
| CN101360495B (zh) * | 2005-11-14 | 2012-03-14 | 阿里亚德医药股份有限公司 | 对癌症病人给药mTOR抑制剂 |
| DE602006009968D1 (de) | 2005-11-15 | 2009-12-03 | Array Biopharma Inc | N4-phenyl-chinazolin-4-aminderivate und verwandte verbindungen als inhibitoren der erbb-typ-i-rezeptortyrosinkinase zur behandlung hyperproliferativer krankheiten |
| CN101484807A (zh) * | 2006-03-31 | 2009-07-15 | 麻省理工学院 | 表达突变型egf受体的肿瘤的治疗 |
| JP2009532497A (ja) * | 2006-04-05 | 2009-09-10 | ノバルティス アクチエンゲゼルシャフト | 癌を処置するための治療剤の組合せ |
| JP2010509400A (ja) | 2006-11-14 | 2010-03-25 | アリアド・ファーマシューティカルズ・インコーポレイテッド | 経口処方組成物 |
| AU2008236997A1 (en) * | 2007-04-10 | 2008-10-16 | Myrexis, Inc. | Methods for treating cancer |
| AU2008236993A1 (en) * | 2007-04-10 | 2008-10-16 | Myrexis, Inc. | Method of treating brain cancer |
| WO2008124828A1 (en) * | 2007-04-10 | 2008-10-16 | Myriad Genetics, Inc. | Methods for treating vascular disruption disorders |
| WO2008124824A1 (en) * | 2007-04-10 | 2008-10-16 | Myriad Genetics, Inc. | Dosages and methods for the treatment of cancer |
| EP2144886A4 (en) * | 2007-04-10 | 2012-10-03 | Myrexis Inc | METHOD OF TREATING MELANOMA |
| US9551033B2 (en) | 2007-06-08 | 2017-01-24 | Genentech, Inc. | Gene expression markers of tumor resistance to HER2 inhibitor treatment |
| CA3006428A1 (en) | 2007-06-08 | 2008-12-18 | Genentech, Inc. | Gene expression markers of tumor resistance to her2 inhibitor treatment |
| US8252805B2 (en) * | 2008-05-07 | 2012-08-28 | Teva Pharmaceutical Industries Ltd. | Forms of lapatinib ditosylate and processes for preparation thereof |
| WO2010027848A2 (en) * | 2008-08-26 | 2010-03-11 | Teva Pharmaceutical Industries Ltd. | Forms of lapatinib compounds and processes for the preparation thereof |
| AR075896A1 (es) * | 2009-03-20 | 2011-05-04 | Genentech Inc | Anticuerpos anti-her (factor de crecimiento epidermico) |
| EP2793893A4 (en) * | 2011-11-23 | 2015-07-08 | Intellikine Llc | IMPROVED TREATMENT REGIMES USING MTOR INHIBITORS |
| EP3101115B1 (en) | 2014-01-31 | 2020-10-21 | Toppan Printing Co., Ltd. | Biomolecule analysis kit and biomolecule analysis method |
| CN108473538B (zh) * | 2015-10-28 | 2022-01-28 | 塔弗达治疗有限公司 | Sstr靶向缀合物及其颗粒和制剂 |
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| ZA932522B (en) * | 1992-04-10 | 1993-12-20 | Res Dev Foundation | Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens |
| CA2216796C (en) * | 1995-03-30 | 2003-09-02 | Pfizer Inc. | Quinazoline derivatives |
| GB9718972D0 (en) * | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| JP4044839B2 (ja) * | 2000-06-22 | 2008-02-06 | ファイザー・プロダクツ・インク | 異常細胞増殖を治療するための置換２環式誘導体 |
| AU2002339687A1 (en) * | 2001-12-12 | 2003-06-23 | Pfizer Products Inc. | Quinazoline derivatives for the treatement of abnormal cell growth |
| HRP20040530A2 (en) * | 2001-12-12 | 2004-10-31 | Pfizer Prod Inc | Salt forms of e-2-methoxy-n-(3-(4-(3-methyl-pyridin-3-yloxy)-phenylamino)-quinazolin-6-yl)-allyl)-acetamide, its preparation and its use against cancer |
| JP4611745B2 (ja) * | 2002-11-20 | 2011-01-12 | アレイ バイオファーマ、インコーポレイテッド | ＥｒｂＢ２及びＥＧＦＲ阻害剤としてのシアノグアニジン及びシアノアミジン |
| RU2005119172A (ru) * | 2002-12-18 | 2006-01-20 | Пфайзер Продактс Инк. (Us) | Производные 4-анилинхиназолина для лечения патологического роста клеток |
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- 2004-08-06 AU AU2004264726A patent/AU2004264726A1/en not_active Abandoned
- 2004-08-06 CN CNA200480023705XA patent/CN1838959A/zh active Pending
- 2004-08-06 BR BRPI0413745-0A patent/BRPI0413745A/pt not_active IP Right Cessation
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- 2004-08-06 WO PCT/IB2004/002580 patent/WO2005016347A1/en not_active Ceased
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- 2004-08-06 JP JP2006523695A patent/JP2007502807A/ja not_active Withdrawn
- 2004-08-06 CA CA002536140A patent/CA2536140A1/en not_active Abandoned
- 2004-08-06 KR KR1020087000092A patent/KR20080014144A/ko not_active Withdrawn
- 2004-08-17 US US10/919,831 patent/US20050119288A1/en not_active Abandoned
- 2004-08-17 AR ARP040102941A patent/AR045268A1/es not_active Application Discontinuation
- 2004-08-17 TW TW093124706A patent/TW200522966A/zh unknown
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2006
- 2006-01-12 IL IL173127A patent/IL173127A0/en unknown
- 2006-01-18 ZA ZA200600517A patent/ZA200600517B/xx unknown
- 2006-02-15 CO CO06015089A patent/CO5670356A2/es not_active Application Discontinuation
- 2006-03-17 NO NO20061252A patent/NO20061252L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20080014144A (ko) | 2008-02-13 |
| TW200522966A (en) | 2005-07-16 |
| CA2536140A1 (en) | 2005-02-24 |
| CN1838959A (zh) | 2006-09-27 |
| WO2005016347A1 (en) | 2005-02-24 |
| SG135193A1 (en) | 2007-09-28 |
| IL173127A0 (en) | 2006-06-11 |
| US20050119288A1 (en) | 2005-06-02 |
| AR045268A1 (es) | 2005-10-19 |
| ZA200600517B (en) | 2007-02-28 |
| RU2006102125A (ru) | 2007-09-27 |
| BRPI0413745A (pt) | 2006-10-24 |
| EP1658080A1 (en) | 2006-05-24 |
| CO5670356A2 (es) | 2006-08-31 |
| MXPA06001989A (es) | 2006-05-17 |
| RU2328287C2 (ru) | 2008-07-10 |
| JP2007502807A (ja) | 2007-02-15 |
| NO20061252L (no) | 2006-05-16 |
| KR20060037447A (ko) | 2006-05-03 |
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