TW200522966A - Dosing schedule for a novel anticancer agent - Google Patents
Dosing schedule for a novel anticancer agent Download PDFInfo
- Publication number
- TW200522966A TW200522966A TW093124706A TW93124706A TW200522966A TW 200522966 A TW200522966 A TW 200522966A TW 093124706 A TW093124706 A TW 093124706A TW 93124706 A TW93124706 A TW 93124706A TW 200522966 A TW200522966 A TW 200522966A
- Authority
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- Taiwan
- Prior art keywords
- methyl
- inhibitor
- group
- yloxy
- phenylamino
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Publications (1)
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| JP (1) | JP2007502807A (enExample) |
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| CN (1) | CN1838959A (enExample) |
| AR (1) | AR045268A1 (enExample) |
| AU (1) | AU2004264726A1 (enExample) |
| BR (1) | BRPI0413745A (enExample) |
| CA (1) | CA2536140A1 (enExample) |
| CO (1) | CO5670356A2 (enExample) |
| IL (1) | IL173127A0 (enExample) |
| MX (1) | MXPA06001989A (enExample) |
| NO (1) | NO20061252L (enExample) |
| RU (1) | RU2328287C2 (enExample) |
| SG (1) | SG135193A1 (enExample) |
| TW (1) | TW200522966A (enExample) |
| WO (1) | WO2005016347A1 (enExample) |
| ZA (1) | ZA200600517B (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2407473A3 (en) | 2002-02-01 | 2012-03-21 | ARIAD Pharmaceuticals, Inc | Method for producing phosphorus-containing compounds |
| US8505468B2 (en) * | 2002-11-19 | 2013-08-13 | Sharp Kabushiki Kaisha | Substrate accommodating tray |
| US7501427B2 (en) * | 2003-08-14 | 2009-03-10 | Array Biopharma, Inc. | Quinazoline analogs as receptor tyrosine kinase inhibitors |
| KR100953246B1 (ko) * | 2003-08-14 | 2010-04-16 | 어레이 바이오파마 인크. | 수용체 티로신 키나아제 억제제로서의 퀴나졸린 유사체 |
| DK1667992T3 (da) | 2003-09-19 | 2007-04-30 | Astrazeneca Ab | Quinazolinderivater |
| RS52119B (sr) * | 2004-05-06 | 2012-08-31 | Warner-Lambert Company Llc | 4-fenilamino-hinazolin-6-il-amidi |
| GB0427131D0 (en) * | 2004-12-10 | 2005-01-12 | Glaxosmithkline Biolog Sa | Novel combination |
| US20080194596A1 (en) * | 2005-06-03 | 2008-08-14 | Frizer Inc. | Therapeutic Combination Including a Selective Erbb2 Inhibitor |
| WO2006138608A2 (en) * | 2005-06-16 | 2006-12-28 | Myriad Genetics, Inc. | Pharmaceutical compositions and use thereof |
| WO2007014335A2 (en) * | 2005-07-27 | 2007-02-01 | The University Of Texas System | Combinations comprising gemcitabine and tyrosine kinase inhibitors for the treatment of pancreatic cancer |
| US8945573B2 (en) | 2005-09-08 | 2015-02-03 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Targeted identification of immunogenic peptides |
| EA015922B1 (ru) * | 2005-11-14 | 2011-12-30 | Ариад Фармасьютикалз, Инк. | ВВЕДЕНИЕ ИНГИБИТОРА mTOR ДЛЯ ЛЕЧЕНИЯ ПАЦИЕНТОВ СО ЗЛОКАЧЕСТВЕННОЙ ОПУХОЛЬЮ |
| ATE507224T1 (de) | 2005-11-15 | 2011-05-15 | Array Biopharma Inc | Verfahren und zwischenverbindungen zur herstellung von n4-phenyl-quinazolin-4-amin derivaten |
| EP2010911A4 (en) * | 2006-03-31 | 2009-05-13 | Massachusetts Inst Technology | TREATMENT OF EGF RECEPTOR MUTANTS EXPRESSING TUMORS |
| RU2008143554A (ru) * | 2006-04-05 | 2010-05-10 | Новартис АГ (CH) | Комбинации терапевтических агентов для лечения рака |
| JP2010509400A (ja) | 2006-11-14 | 2010-03-25 | アリアド・ファーマシューティカルズ・インコーポレイテッド | 経口処方組成物 |
| CA2720989A1 (en) * | 2007-04-10 | 2008-10-16 | Myrexis, Inc. | Methods for treating cancer |
| WO2008124828A1 (en) * | 2007-04-10 | 2008-10-16 | Myriad Genetics, Inc. | Methods for treating vascular disruption disorders |
| CA2720983A1 (en) * | 2007-04-10 | 2008-10-16 | Myrexis, Inc. | Method of treating melanoma |
| KR20100016385A (ko) * | 2007-04-10 | 2010-02-12 | 미리어드 파마슈티칼스, 인코포레이티드 | 뇌종양 치료방법 |
| EP2144887A4 (en) * | 2007-04-10 | 2012-10-03 | Myrexis Inc | PHARMACEUTICAL FORMS AND METHOD FOR THE TREATMENT OF CANCER |
| ES2417148T3 (es) | 2007-06-08 | 2013-08-06 | Genentech, Inc. | Marcadores de expresión génica de la resistencia tumoral al tratamiento con inhibidor de HER2 |
| US9551033B2 (en) | 2007-06-08 | 2017-01-24 | Genentech, Inc. | Gene expression markers of tumor resistance to HER2 inhibitor treatment |
| WO2009137714A2 (en) * | 2008-05-07 | 2009-11-12 | Teva Pharmaceutical Industries Ltd. | Forms of lapatinib ditosylate and processes for preparation thereof |
| WO2010027848A2 (en) * | 2008-08-26 | 2010-03-11 | Teva Pharmaceutical Industries Ltd. | Forms of lapatinib compounds and processes for the preparation thereof |
| MA33198B1 (fr) | 2009-03-20 | 2012-04-02 | Genentech Inc | Anticorps anti-her di-spécifiques |
| WO2013078440A2 (en) * | 2011-11-23 | 2013-05-30 | Intellikine, Llc | Enhanced treatment regimens using mtor inhibitors |
| EP3101115B1 (en) | 2014-01-31 | 2020-10-21 | Toppan Printing Co., Ltd. | Biomolecule analysis kit and biomolecule analysis method |
| EP3368546A4 (en) | 2015-10-28 | 2019-06-26 | Tarveda Therapeutics, Inc. | AGAINST SSTR CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA932522B (en) * | 1992-04-10 | 1993-12-20 | Res Dev Foundation | Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens |
| DE122005000053I2 (de) * | 1995-03-30 | 2008-01-17 | Pfizer Prod Inc | Chinazolinderivate |
| GB9718972D0 (en) * | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| HUP0301120A2 (hu) * | 2000-06-22 | 2003-08-28 | Pfizer Products Inc. | Szubsztituált fenilamino-kinazolin-származékok, alkalmazásuk rendellenes sejtnövekedés kezelésére és azokat tartalmazó gyógyszerkészítmények |
| AU2002339687A1 (en) * | 2001-12-12 | 2003-06-23 | Pfizer Products Inc. | Quinazoline derivatives for the treatement of abnormal cell growth |
| EA007412B1 (ru) * | 2001-12-12 | 2006-10-27 | Пфайзер Продактс Инк. | Соли е-2-метокси-n-(3-(4-(3-метилпиридин-3-илокси)фениламино)хиназолин-6-ил-аллил)ацетамида, их получение и их применение против рака |
| NZ540092A (en) * | 2002-11-20 | 2007-06-29 | Array Biopharma Inc | Cyanoguanidines and cyanoamidines as ErbB2 and EGFR inhibitors |
| CN1729001A (zh) * | 2002-12-18 | 2006-02-01 | 辉瑞产品公司 | 用于治疗异常细胞生长的4－苯胺基喹唑啉衍生物 |
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- 2004-08-06 JP JP2006523695A patent/JP2007502807A/ja not_active Withdrawn
- 2004-08-06 CN CNA200480023705XA patent/CN1838959A/zh active Pending
- 2004-08-06 CA CA002536140A patent/CA2536140A1/en not_active Abandoned
- 2004-08-06 SG SG200706063-5A patent/SG135193A1/en unknown
- 2004-08-06 RU RU2006102125/14A patent/RU2328287C2/ru not_active IP Right Cessation
- 2004-08-06 AU AU2004264726A patent/AU2004264726A1/en not_active Abandoned
- 2004-08-06 KR KR1020087000092A patent/KR20080014144A/ko not_active Withdrawn
- 2004-08-06 EP EP04744217A patent/EP1658080A1/en not_active Withdrawn
- 2004-08-06 KR KR1020067003190A patent/KR20060037447A/ko not_active Ceased
- 2004-08-06 BR BRPI0413745-0A patent/BRPI0413745A/pt not_active IP Right Cessation
- 2004-08-06 WO PCT/IB2004/002580 patent/WO2005016347A1/en not_active Ceased
- 2004-08-06 MX MXPA06001989A patent/MXPA06001989A/es not_active Application Discontinuation
- 2004-08-17 TW TW093124706A patent/TW200522966A/zh unknown
- 2004-08-17 AR ARP040102941A patent/AR045268A1/es not_active Application Discontinuation
- 2004-08-17 US US10/919,831 patent/US20050119288A1/en not_active Abandoned
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2006
- 2006-01-12 IL IL173127A patent/IL173127A0/en unknown
- 2006-01-18 ZA ZA200600517A patent/ZA200600517B/xx unknown
- 2006-02-15 CO CO06015089A patent/CO5670356A2/es not_active Application Discontinuation
- 2006-03-17 NO NO20061252A patent/NO20061252L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2536140A1 (en) | 2005-02-24 |
| MXPA06001989A (es) | 2006-05-17 |
| ZA200600517B (en) | 2007-02-28 |
| CN1838959A (zh) | 2006-09-27 |
| SG135193A1 (en) | 2007-09-28 |
| AR045268A1 (es) | 2005-10-19 |
| NO20061252L (no) | 2006-05-16 |
| KR20060037447A (ko) | 2006-05-03 |
| BRPI0413745A (pt) | 2006-10-24 |
| JP2007502807A (ja) | 2007-02-15 |
| WO2005016347A1 (en) | 2005-02-24 |
| RU2328287C2 (ru) | 2008-07-10 |
| CO5670356A2 (es) | 2006-08-31 |
| EP1658080A1 (en) | 2006-05-24 |
| KR20080014144A (ko) | 2008-02-13 |
| IL173127A0 (en) | 2006-06-11 |
| US20050119288A1 (en) | 2005-06-02 |
| AU2004264726A1 (en) | 2005-02-24 |
| RU2006102125A (ru) | 2007-09-27 |
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