AU2004226815B2 - Crystalline N-formyl hydroxylamine compounds - Google Patents

Crystalline N-formyl hydroxylamine compounds Download PDF

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Publication number
AU2004226815B2
AU2004226815B2 AU2004226815A AU2004226815A AU2004226815B2 AU 2004226815 B2 AU2004226815 B2 AU 2004226815B2 AU 2004226815 A AU2004226815 A AU 2004226815A AU 2004226815 A AU2004226815 A AU 2004226815A AU 2004226815 B2 AU2004226815 B2 AU 2004226815B2
Authority
AU
Australia
Prior art keywords
hydrogen
alkyl
formula
crystalline salt
crystalline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2004226815A
Other languages
English (en)
Other versions
AU2004226815A1 (en
Inventor
Joginder Singh Bajwa
Hui Liu
Martin Muller
Joel Slade
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33131903&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2004226815(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Publication of AU2004226815A1 publication Critical patent/AU2004226815A1/en
Application granted granted Critical
Publication of AU2004226815B2 publication Critical patent/AU2004226815B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2004226815A 2003-04-02 2004-04-01 Crystalline N-formyl hydroxylamine compounds Ceased AU2004226815B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45972603P 2003-04-02 2003-04-02
US60/459,726 2003-04-02
PCT/EP2004/003478 WO2004087133A1 (en) 2003-04-02 2004-04-01 Crystalline n-formyl hydroxylamine compounds

Publications (2)

Publication Number Publication Date
AU2004226815A1 AU2004226815A1 (en) 2004-10-14
AU2004226815B2 true AU2004226815B2 (en) 2007-07-19

Family

ID=33131903

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2004226815A Ceased AU2004226815B2 (en) 2003-04-02 2004-04-01 Crystalline N-formyl hydroxylamine compounds

Country Status (25)

Country Link
US (1) US20070135353A1 (https=)
EP (1) EP1613305A1 (https=)
JP (1) JP2006522054A (https=)
KR (1) KR20060002915A (https=)
CN (1) CN1764450A (https=)
AR (1) AR043804A1 (https=)
AU (1) AU2004226815B2 (https=)
BR (1) BRPI0409009A (https=)
CA (1) CA2520682A1 (https=)
CL (1) CL2004000705A1 (https=)
CO (1) CO5630028A2 (https=)
EC (1) ECSP056043A (https=)
IS (1) IS8093A (https=)
MA (1) MA27763A1 (https=)
MX (1) MXPA05010610A (https=)
MY (1) MY136854A (https=)
NO (1) NO20055097L (https=)
NZ (1) NZ542432A (https=)
PE (1) PE20050392A1 (https=)
RU (1) RU2005133660A (https=)
SG (1) SG166681A1 (https=)
TN (1) TNSN05248A1 (https=)
TW (1) TW200427458A (https=)
WO (1) WO2004087133A1 (https=)
ZA (1) ZA200507179B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1406893B1 (en) 2001-06-15 2007-04-18 Vicuron Pharmaceuticals, Inc. Pyrrolidine bicyclic compounds
ATE417826T1 (de) 2002-09-19 2009-01-15 Novartis Pharma Gmbh Verfahren zur herstellung von zwischenprodukten
MXPA05008842A (es) 2003-02-21 2005-10-05 Novartis Ag Proceso quimico.
GT200600196A (es) * 2005-05-23 2007-01-15 Compuestos n-formil de hidroxilamina
JP7001898B2 (ja) * 2016-05-11 2022-01-20 グアンドン・ヘボ・ファーマシューティカル・カンパニー・リミテッド スピロ３員環、スピロ５員環系ペプチドデホルミラーゼ阻害剤および抗菌と抗腫瘍におけるその使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3282986A (en) * 1960-10-06 1966-11-01 Merck & Co Inc N-acylated hydroxamic acids and derivatives thereof
DK1052984T3 (da) * 1998-02-07 2004-09-20 Vernalis Oxford Ltd Antibakterielle midler
AR036053A1 (es) * 2001-06-15 2004-08-04 Versicor Inc Compuestos de n-formil-hidroxilamina, un proceso para su preparacion y composiciones farmaceuticas

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
References cited in WO 2004/087133 *

Also Published As

Publication number Publication date
NO20055097L (no) 2005-12-22
CA2520682A1 (en) 2004-10-14
US20070135353A1 (en) 2007-06-14
RU2005133660A (ru) 2006-06-10
NZ542432A (en) 2009-04-30
PE20050392A1 (es) 2005-06-19
TNSN05248A1 (en) 2007-06-11
MXPA05010610A (es) 2005-11-23
BRPI0409009A (pt) 2006-03-28
IS8093A (is) 2005-10-27
AU2004226815A1 (en) 2004-10-14
CO5630028A2 (es) 2006-04-28
SG166681A1 (en) 2010-12-29
CL2004000705A1 (es) 2005-01-14
WO2004087133A1 (en) 2004-10-14
MA27763A1 (fr) 2006-02-01
MY136854A (en) 2008-11-28
ZA200507179B (en) 2006-04-26
NO20055097D0 (no) 2005-11-01
KR20060002915A (ko) 2006-01-09
ECSP056043A (es) 2006-01-27
JP2006522054A (ja) 2006-09-28
TW200427458A (en) 2004-12-16
EP1613305A1 (en) 2006-01-11
AR043804A1 (es) 2005-08-10
CN1764450A (zh) 2006-04-26

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired