AU2002359291C1 - Azole derivatives and pharmaceutical compositions containing them - Google Patents

Azole derivatives and pharmaceutical compositions containing them Download PDF

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Publication number
AU2002359291C1
AU2002359291C1 AU2002359291A AU2002359291A AU2002359291C1 AU 2002359291 C1 AU2002359291 C1 AU 2002359291C1 AU 2002359291 A AU2002359291 A AU 2002359291A AU 2002359291 A AU2002359291 A AU 2002359291A AU 2002359291 C1 AU2002359291 C1 AU 2002359291C1
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Prior art keywords
optionally substituted
alkyl
imidazol
iodo
methyl
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AU2002359291A
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AU2002359291B2 (en
AU2002359291A1 (en
AU2002359291B8 (en
Inventor
Stephen J Arkinstall
Antonio Arulanandam
Peter Blume-Jensen
Xuliang Jiang
Sharad Magar
Roustem Nabioullin
John Yingsheng Zhang
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Merck Serono SA
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Merck Serono SA
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Assigned to LABORATOIRES SERONO SA reassignment LABORATOIRES SERONO SA Request for Assignment Assignors: APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.
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Priority to AU2008202731A priority Critical patent/AU2008202731A1/en
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Assigned to MERCK SERONO SA reassignment MERCK SERONO SA Request for Assignment Assignors: LABORATOIRES SERONO SA
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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/60Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
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    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • C07D233/61Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms not forming part of a nitro radical, attached to ring nitrogen atoms
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AU2002359291A 2001-10-23 2002-10-23 Azole derivatives and pharmaceutical compositions containing them Ceased AU2002359291C1 (en)

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CN110845703A (zh) * 2019-10-28 2020-02-28 上海瀚岱化学有限公司 一种水性环氧树脂及其制备方法
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JP7725076B2 (ja) 2020-04-28 2025-08-19 ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミシガン グルコシルセラミド合成酵素のピリジン阻害剤及びそれらを使用する治療方法
CN112646123A (zh) * 2020-12-18 2021-04-13 江西瀚泰新材料科技有限公司 一种低粘度水性环氧树脂及其制备方法
CN112759742A (zh) * 2020-12-18 2021-05-07 江西瀚泰新材料科技有限公司 一种增韧型水性环氧树脂及其制备方法
CN112794989A (zh) * 2020-12-18 2021-05-14 江西瀚泰新材料科技有限公司 一种增韧阻燃水性环氧树脂及其制备方法

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US20070293555A1 (en) 2007-12-20
IL161580A0 (en) 2004-09-27
JP4602667B2 (ja) 2010-12-22
AU2002359291B2 (en) 2008-04-03
WO2003035626A3 (en) 2003-11-06
US20050054706A1 (en) 2005-03-10
EP1438295B1 (en) 2012-08-15
ES2393186T3 (es) 2012-12-19
EP2332922A1 (en) 2011-06-15
WO2003035626A2 (en) 2003-05-01
JP2005508972A (ja) 2005-04-07
US7541375B2 (en) 2009-06-02
CA2463101A1 (en) 2003-05-01
AU2008202731A1 (en) 2008-07-17
AU2002359291B8 (en) 2008-04-17
EP1438295A2 (en) 2004-07-21
US7253199B2 (en) 2007-08-07

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