AU2002342968B2 - Fatty acid compounds, preparation and uses thereof - Google Patents

Fatty acid compounds, preparation and uses thereof Download PDF

Info

Publication number
AU2002342968B2
AU2002342968B2 AU2002342968A AU2002342968A AU2002342968B2 AU 2002342968 B2 AU2002342968 B2 AU 2002342968B2 AU 2002342968 A AU2002342968 A AU 2002342968A AU 2002342968 A AU2002342968 A AU 2002342968A AU 2002342968 B2 AU2002342968 B2 AU 2002342968B2
Authority
AU
Australia
Prior art keywords
group
atom
carbon atoms
saturated
linear
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2002342968A
Other languages
English (en)
Other versions
AU2002342968A1 (en
Inventor
Karine Caumont-Bertrand
Jamila Najib-Fruchart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genfit SA
Original Assignee
Genfit SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genfit SA filed Critical Genfit SA
Publication of AU2002342968A1 publication Critical patent/AU2002342968A1/en
Application granted granted Critical
Publication of AU2002342968B2 publication Critical patent/AU2002342968B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/20—Esters of monothiocarboxylic acids
    • C07C327/28—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Cosmetics (AREA)
AU2002342968A 2001-08-09 2002-08-08 Fatty acid compounds, preparation and uses thereof Ceased AU2002342968B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0110645 2001-08-09
FR0110645A FR2828487B1 (fr) 2001-08-09 2001-08-09 Nouveaux composes derives d'acides gras, preparation et utilisations
PCT/FR2002/002831 WO2003014073A1 (fr) 2001-08-09 2002-08-08 Composes derives d'acides gras preparation et utilisations

Publications (2)

Publication Number Publication Date
AU2002342968A1 AU2002342968A1 (en) 2003-06-19
AU2002342968B2 true AU2002342968B2 (en) 2008-05-15

Family

ID=8866413

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002342968A Ceased AU2002342968B2 (en) 2001-08-09 2002-08-08 Fatty acid compounds, preparation and uses thereof

Country Status (13)

Country Link
US (1) US7375135B2 (enExample)
EP (1) EP1673338B1 (enExample)
JP (1) JP2004537595A (enExample)
AT (1) ATE373638T1 (enExample)
AU (1) AU2002342968B2 (enExample)
CA (1) CA2456288A1 (enExample)
CY (1) CY1107806T1 (enExample)
DE (1) DE60222596T2 (enExample)
DK (1) DK1673338T3 (enExample)
ES (1) ES2292824T3 (enExample)
FR (1) FR2828487B1 (enExample)
PT (1) PT1673338E (enExample)
WO (1) WO2003014073A1 (enExample)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO328803B1 (no) 2000-03-03 2010-05-18 Thia Medica Nye fettsyreanaloger
FR2828487B1 (fr) 2001-08-09 2005-05-27 Genfit S A Nouveaux composes derives d'acides gras, preparation et utilisations
AU2003278602C1 (en) 2002-06-20 2010-08-12 Pronova Biopharma Norge As Sulfur-containing phospholipid derivatives
FR2850650B1 (fr) * 2003-01-31 2005-03-25 Genfit S A Utilisation therapeutique d'acylglycerols et de leurs analogues azotes et sulfures
FR2850869B1 (fr) * 2003-02-12 2005-03-25 Genfit S A Utilisations d'aminopropanediols acyles et de leurs analogues azotes et sulfures
FR2850870B1 (fr) * 2003-02-12 2006-07-28 Genfit S A Utilisation therapeutique de glycerols acyles et de leurs analogues azotes et sulfures
FR2853834B1 (fr) * 2003-04-17 2008-08-15 Vincience Composition cosmetique ou pharmaceutique comprenant l'association d'au moins un diacyglycerol et d'au moins un alcool gras
FR2858216B1 (fr) * 2003-07-31 2008-04-04 Oreal Composition contenant un 2-thioacetamide, son utilisation pour stimuler la pousse des fibres keratiniques et/ou freiner leur chute
RU2261705C1 (ru) * 2004-01-29 2005-10-10 Медведев Илья Николаевич Способ лечения тромбоцитопатии при метаболическом синдроме
JP2008506773A (ja) * 2004-07-19 2008-03-06 ティア メディカ アクスイェ セルスカプ タンパク質材料と非酸化性脂肪酸体を含む組成物
RU2394598C2 (ru) * 2004-07-19 2010-07-20 Тиа Медика Ас Композиция, содержащая белковый материал и соединения, содержащие неокисляющиеся структурные элементы жирных кислот
DE102006019907A1 (de) * 2006-04-28 2007-10-31 Müller-Enoch, Dieter, Prof. Dr. Verwendung von substituierten Glycerinderivaten zur Herstellung einer pharmazeutischen Zubereitung
DE102007051338A1 (de) * 2007-10-26 2009-04-30 Müller-Enoch, Dieter, Prof. Dr. Verwendung von substituierten Glycerinderivaten zur Herstellung einer pharmazeutischen Zubereitung zur Behandlung und zur Vorbeugung von Dyslipidämien
WO2009061208A1 (en) 2007-11-09 2009-05-14 Pronova Biopharma Norge As Lipid compounds for use in cosmetic products, as food supplement or as a medicament
EP2147910A1 (en) 2008-07-15 2010-01-27 Pronova BioPharma Norge AS Novel lipid compounds
KR101783817B1 (ko) 2009-05-08 2017-10-23 프로노바 바이오파마 너지 에이에스 심혈관 질병, 대사 질병, 및 염증성 질환 분야관련 질병의 치료를 위한 다중 불포화 지방산
WO2010149170A1 (en) * 2009-06-24 2010-12-29 Københavns Universitet Treatment of insulin resistance and obesity by stimulating glp-1 release
SG10201509127YA (en) 2010-11-05 2015-12-30 Pronova Biopharma Norge As Methods of treatment using lipid compounds
US11351139B2 (en) 2013-02-28 2022-06-07 Basf As Composition comprising a lipid compound, a triglyceride, and a surfactant, and methods of using the same
WO2014140934A2 (en) 2013-03-11 2014-09-18 Life Science Nutrition As Natural lipids containing non-oxidizable fatty acids
AU2014228387B2 (en) 2013-03-11 2016-09-01 Sciadonics, Inc. Lipid compositions containing bioactive fatty acids
US9744542B2 (en) 2013-07-29 2017-08-29 Apeel Technology, Inc. Agricultural skin grafting
AU2016256552B2 (en) 2015-04-28 2021-04-01 Pronova Biopharma Norge As Use of structurally enhanced fatty acids containing sulphur for preventing and/or treating non-alcoholic steatohepatitis
JP7157531B2 (ja) 2015-05-20 2022-10-20 アピール テクノロジー,インコーポレイテッド 植物抽出物組成物およびその調製方法
EP4793326A2 (en) 2015-09-16 2026-08-19 Apeel Technology, Inc. Method for forming a protective coating by applying fatty acid glyceride compounds to a surface
FR3044556B1 (fr) 2015-12-08 2019-10-18 Pierre Fabre Dermo-Cosmetique Utilisation de diglyceride 1,3 dans une composition topique pour lutter contre la fragilisation de la barriere cutanee
EP3386303B1 (en) 2015-12-10 2020-03-11 Apeel Technology, Inc. Process for depolymerising cutin
TWI731928B (zh) 2016-01-26 2021-07-01 美商aPEEL科技公司 製備及保存經消毒產品之方法
WO2018094269A1 (en) 2016-11-17 2018-05-24 Apeel Technology, Inc. Compositions formed from plant extracts and methods of preparation thereof
AU2018354090B2 (en) 2017-10-23 2024-10-24 Epitracker, Inc. Fatty acid analogs and their use in the treatment of conditions related to metabolic syndrome
IL308604B2 (en) 2017-12-06 2025-08-01 Basf As Fatty acid derivatives for treating non-alcoholic steatohepatitis
AU2019271067B2 (en) * 2018-05-16 2023-08-03 Epitracker, Inc. Compositions and methods for diagnosis and treatment of conditions related to aging
EP3796976A4 (en) 2018-05-23 2022-03-30 Epitracker, Inc. COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF CONDITIONS RELATED TO LONGEVITY AND QUALITY OF AGING
US12245605B2 (en) 2018-09-05 2025-03-11 Apeel Technology, Inc. Compounds and formulations for protective coatings
EP3908374A4 (en) 2019-01-09 2022-12-28 Epitracker, Inc. COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF NEURODEGENERATIVE DISEASES
JP7404382B2 (ja) 2019-03-04 2023-12-25 エピトラッカー インコーポレイテッド 脂肪酸アナログ、ならびに認知機能障害、行動症状および慢性疼痛の処置におけるそれらの使用
EP4114181A1 (en) 2020-03-04 2023-01-11 Apeel Technology, Inc. Coated agricultural products and corresponding methods
IL302360B2 (en) 2020-10-30 2025-01-01 Apeel Tech Inc Preparations and methods of their preparation
US12408680B2 (en) 2021-09-08 2025-09-09 Apeel Technology, Inc. Compounds and formulations for protective coatings
JP2024539823A (ja) 2021-11-03 2024-10-31 エピトラッカー インコーポレイテッド 老化の質および寿命に関係する状態の治療のためのペンタデカノイルカルニチン
US12133863B1 (en) * 2023-06-07 2024-11-05 King Saud University Green synthesis of silver nanoparticles encapsulated in a nanostructured lipid carrier

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2010154A (en) * 1933-06-27 1935-08-06 Herbert S Kreighbaum Ether acid ester of polyhydric alcohols
DE2028240A1 (de) * 1969-06-11 1970-12-23 Mitsubishi Petrochemical Co, Ltd., Tokio; Shipro Kasei Kaisha Ltd., Osaka; (Japan) Gegen thermischen Abbau stabilisierte Polyolefinzusammensetzung
US4134770A (en) * 1976-09-22 1979-01-16 Mitsubishi Paper Mills, Ltd. Gelatin-containing photographic layer incorporated with hardener
EP0018342A1 (fr) * 1979-03-06 1980-10-29 Sanofi S.A. Nouveaux dérivés du glycerol, leurs procédés de préparation ainsi que les compositions pharmaceutiques les contenant
EP0447553A1 (en) * 1989-09-11 1991-09-25 Kao Corporation Bleaching composition

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5738616B2 (enExample) * 1974-06-19 1982-08-17
JPS5782573A (en) * 1980-11-05 1982-05-24 Matsumoto Yushi Seiyaku Kk Smoothening treatment agent for thermoplastic synthetic fiber
GB8813012D0 (en) 1988-06-02 1988-07-06 Norsk Hydro As Non-b-oxidizable fatty acid analogues to reduce concentration of cholesterol & triglycerides in blood of mammals
NO952796D0 (no) 1995-07-14 1995-07-14 Rolf Berge Fettsyre analoger med ikkeoksyderbart B-sete, fremstilling og anvendelse i krapeutiske preparater
US5885595A (en) * 1996-05-13 1999-03-23 Elizabeth Arden Co., Division Of Conopco, Inc. Cosmetic composition with a retinol fatty acid ester
AU9036998A (en) 1997-08-29 1999-03-16 Johns Hopkins University, The Antimicrobial compounds
JP2000169443A (ja) 1998-10-02 2000-06-20 Sankyo Co Ltd ジチオ―ル誘導体
US6117904A (en) * 1999-09-03 2000-09-12 Murphy; Donald M. Treatment of pruritus
FR2828487B1 (fr) 2001-08-09 2005-05-27 Genfit S A Nouveaux composes derives d'acides gras, preparation et utilisations
AU2003278602C1 (en) 2002-06-20 2010-08-12 Pronova Biopharma Norge As Sulfur-containing phospholipid derivatives
FR2850650B1 (fr) 2003-01-31 2005-03-25 Genfit S A Utilisation therapeutique d'acylglycerols et de leurs analogues azotes et sulfures
FR2850969B1 (fr) 2003-02-12 2005-03-25 Genfit S A Aminopropanediols acyles et analogues et leurs utilisations therapeutiques
FR2850869B1 (fr) 2003-02-12 2005-03-25 Genfit S A Utilisations d'aminopropanediols acyles et de leurs analogues azotes et sulfures
FR2850870B1 (fr) 2003-02-12 2006-07-28 Genfit S A Utilisation therapeutique de glycerols acyles et de leurs analogues azotes et sulfures

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2010154A (en) * 1933-06-27 1935-08-06 Herbert S Kreighbaum Ether acid ester of polyhydric alcohols
DE2028240A1 (de) * 1969-06-11 1970-12-23 Mitsubishi Petrochemical Co, Ltd., Tokio; Shipro Kasei Kaisha Ltd., Osaka; (Japan) Gegen thermischen Abbau stabilisierte Polyolefinzusammensetzung
US4134770A (en) * 1976-09-22 1979-01-16 Mitsubishi Paper Mills, Ltd. Gelatin-containing photographic layer incorporated with hardener
EP0018342A1 (fr) * 1979-03-06 1980-10-29 Sanofi S.A. Nouveaux dérivés du glycerol, leurs procédés de préparation ainsi que les compositions pharmaceutiques les contenant
EP0447553A1 (en) * 1989-09-11 1991-09-25 Kao Corporation Bleaching composition

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
Chemical Abstracts Registry Numbers 58888-36-1 and 58888-37-2 *
Chemical Abstracts Registry Numbers 83995-03-3 *
Chemistry and Physics of Lipids 112(1):59- *
Journal of Biological Chemistry 263(29):14832-8 *
Journal of the Chemical Society 51(13):165-9 *
Journal OrganicChemistry 58(7):1952-4 *
Liebigs Ann. Chem.1980 pp 858-62 *

Also Published As

Publication number Publication date
US7375135B2 (en) 2008-05-20
CY1107806T1 (el) 2013-06-19
EP1673338A1 (fr) 2006-06-28
ATE373638T1 (de) 2007-10-15
CA2456288A1 (fr) 2003-02-20
WO2003014073A1 (fr) 2003-02-20
ES2292824T3 (es) 2008-03-16
EP1673338B1 (fr) 2007-09-19
DE60222596D1 (de) 2007-10-31
DK1673338T3 (da) 2008-01-14
DE60222596T2 (de) 2008-07-24
US20040192908A1 (en) 2004-09-30
PT1673338E (pt) 2007-12-12
FR2828487A1 (fr) 2003-02-14
FR2828487B1 (fr) 2005-05-27
JP2004537595A (ja) 2004-12-16

Similar Documents

Publication Publication Date Title
US7375135B2 (en) Fatty acid derivatives; preparation and uses thereof
US11685735B2 (en) Pharmaceutical composition comprising berberine salts for the treatment of various diseases or disorders
US5093365A (en) Non-β-oxidizable fatty acid analogues with the effect to reduce the concentration of cholesterol and triglycerides in blood of mammals
CN102427809B (zh) 用于治疗代谢性疾病的抗炎剂和抗氧化剂轭合物
AU2016228304B2 (en) Isoprenyl compounds and methods thereof
US20020048798A1 (en) Novel antioxidants
ES2287529T3 (es) Composicion a base de derivados de 1,3-difenilprop-2-en-1-ona sustituidos, preparaciones y usos de la misma.
AU734431B2 (en) Non-beta-oxidizable fatty analogues, their uses as therapeutic active medicaments, and preparation thereof
WO2003084532A1 (en) Lipoic acid analogs useful as provitamins and antioxidants
KR20020072296A (ko) 특이 구조를 가진 일 군의 항암 화합물 및 그 제조방법
CA2572796A1 (en) Lipid-amino acid conjugates and methods of use
US7547729B2 (en) 1,3-diphenylprop-2-en-1-one derivative compounds, preparation method thereof and uses of same
CA2627211C (fr) Derives d'amino-acides contenant un groupement disulfanyle comme inhibiteurs mixtes de la neprilysine et de l'aminopeptidase n
US20060035977A1 (en) Uses of acylated aminopropanediols and sulphur and nitrogen analogues of same f
US20060252827A1 (en) Therapeutic use of of acyglycerols and the nitrogen-and sulphur-containing analogues thereof
EP1940818A1 (fr) Derives d'amino-acides contenant un groupement disulfanyle comme inhibiteurs mixtes de la neprilysine et de l 'aminopeptidase n
MXPA05008634A (es) Aminopropanodioles acilados y analogos y su utilizacion terapeutica.

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired