AU2002328972A1 - Piperidine derivatives as antibacterial agents - Google Patents

Piperidine derivatives as antibacterial agents

Info

Publication number
AU2002328972A1
AU2002328972A1 AU2002328972A AU2002328972A AU2002328972A1 AU 2002328972 A1 AU2002328972 A1 AU 2002328972A1 AU 2002328972 A AU2002328972 A AU 2002328972A AU 2002328972 A AU2002328972 A AU 2002328972A AU 2002328972 A1 AU2002328972 A1 AU 2002328972A1
Authority
AU
Australia
Prior art keywords
piperidine derivatives
antibacterial agents
derivatives
piperidine
mammals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002328972A
Other languages
English (en)
Inventor
David Thomas Davies
Graham Elgin Jones
Roger Edward Markwell
Neil David Pearson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of AU2002328972A1 publication Critical patent/AU2002328972A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU2002328972A 2001-07-26 2002-07-25 Piperidine derivatives as antibacterial agents Abandoned AU2002328972A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0118238.5 2001-07-26
GBGB0118238.5A GB0118238D0 (en) 2001-07-26 2001-07-26 Medicaments
PCT/EP2002/008319 WO2003010138A2 (en) 2001-07-26 2002-07-25 Piperidine derivatives as antibacterial agents

Publications (1)

Publication Number Publication Date
AU2002328972A1 true AU2002328972A1 (en) 2003-02-17

Family

ID=9919236

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002328972A Abandoned AU2002328972A1 (en) 2001-07-26 2002-07-25 Piperidine derivatives as antibacterial agents

Country Status (9)

Country Link
US (1) US20040198756A1 (cg-RX-API-DMAC7.html)
EP (1) EP1419155B1 (cg-RX-API-DMAC7.html)
JP (1) JP2005504747A (cg-RX-API-DMAC7.html)
AT (1) ATE344799T1 (cg-RX-API-DMAC7.html)
AU (1) AU2002328972A1 (cg-RX-API-DMAC7.html)
DE (1) DE60215951T2 (cg-RX-API-DMAC7.html)
ES (1) ES2274999T3 (cg-RX-API-DMAC7.html)
GB (1) GB0118238D0 (cg-RX-API-DMAC7.html)
WO (1) WO2003010138A2 (cg-RX-API-DMAC7.html)

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US7618959B2 (en) 2002-11-05 2009-11-17 Smithklinebeecham Corp Antibacterial agents
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FR2867472B1 (fr) * 2004-03-12 2008-07-18 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
TWI350168B (en) 2004-05-07 2011-10-11 Incyte Corp Amido compounds and their use as pharmaceuticals
EP1768954A4 (en) 2004-06-24 2008-05-28 Incyte Corp 2-METHYLPROPANAMIDES AND THEIR USE AS PHARMACEUTICALS
WO2006017326A1 (en) 2004-07-13 2006-02-16 Glaxo Group Limited Antibacterial agents
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US7605169B2 (en) 2005-01-25 2009-10-20 Glaxo Group Limited Antibacterial agents
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JP2009528365A (ja) * 2006-02-28 2009-08-06 アムゲン インコーポレイティッド ホスホジエステラーゼ１０阻害剤としてのシンノリン及びキナゾリン誘導体
AU2007223801A1 (en) * 2006-03-08 2007-09-13 Amgen Inc. Quinoline and isoquinoline derivatives as phosphodiesterase 10 inhibitors
JP2009532504A (ja) 2006-04-06 2009-09-10 グラクソ グループ リミテッド 抗菌薬
ATE481406T1 (de) 2006-04-06 2010-10-15 Glaxo Group Ltd Pyrrolochinoxalinonderivate als antibakterielle mittel
GB0613208D0 (en) 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
EP1992628A1 (en) 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
US20100210633A1 (en) * 2006-10-12 2010-08-19 Epix Delaware, Inc. Carboxamide compounds and their use
KR101567096B1 (ko) * 2007-04-20 2015-11-06 글락소 그룹 리미티드 항균제로서의 트리시클릭 질소 함유 화합물
MX2009012117A (es) 2007-05-09 2009-11-23 Pfizer Composiciones y derivados heterociclicos sustituidos y su uso farmaceutico como antibacterianos.
CL2008001839A1 (es) 2007-06-21 2009-01-16 Incyte Holdings Corp Compuestos derivados de 2,7-diazaespirociclos, inhibidores de 11-beta hidroxil esteroide deshidrogenasa tipo 1; composicion farmaceutica que comprende a dichos compuestos; utiles para tratar la obesidad, diabetes, intolerancia a la glucosa, diabetes tipo ii, entre otras enfermedades.
BRPI0820701A2 (pt) 2007-12-11 2015-06-16 Cytopathfinder Inc Composto de carboxamida e seu uso como agonistas do receptor de quimiocina
EP2080761A1 (en) 2008-01-18 2009-07-22 Glaxo Group Limited Compounds
ES2539947T3 (es) * 2008-06-02 2015-07-07 Cipla Limited Procedimiento para la síntesis de arformoterol
JP2012505866A (ja) 2008-10-17 2012-03-08 グラクソ グループ リミテッド 抗菌剤として使用される三環式窒素化合物
US8318940B2 (en) 2009-01-15 2012-11-27 Glaxo Group Limited Naphthyridin-2 (1 H)-one compounds useful as antibacterials
TW201209056A (en) * 2010-05-25 2012-03-01 Taisho Pharmaceutical Co Ltd Novel heterocyclic compound or salt thereof
CN102267995A (zh) * 2010-06-04 2011-12-07 艾琪康医药科技（上海）有限公司 一种制备二氮杂螺环化合物的方法
EP2651884A2 (en) * 2010-12-14 2013-10-23 Merck Sharp & Dohme Corp. Process and intermediates for preparing macrolactams
AR089929A1 (es) 2012-02-10 2014-10-01 Actelion Pharmaceuticals Ltd Proceso para manufacturar un derivado de naftiridina
DK2841425T3 (en) * 2012-04-27 2016-06-27 Janssen Pharmaceutica Nv ANTIBACTERIAL QUINOLIN DERIVATIVES
CN104254528B (zh) * 2012-04-27 2017-06-06 詹森药业有限公司 抗菌的喹啉衍生物
BR112017003705B1 (pt) 2014-08-22 2022-07-12 Glaxosmithkline Intellectual Property Development Limited Compostos contendo nitrogênio tricíclicos para o tratamento de infecção por neisseria gonorrhoea
UY36851A (es) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas
WO2021076886A1 (en) 2019-10-18 2021-04-22 The Regents Of The University Of California 3-phenylsulphonyl-quinoline derivatives as agents for treating pathogenic blood vessels disorders
CN116102537B (zh) * 2021-11-10 2024-10-01 四川大学 一种喹啉酮类衍生物及其制备方法和用途

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EP0541486A1 (de) * 1991-11-07 1993-05-12 Ciba-Geigy Ag Polycyclische Konjugate
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GB9822450D0 (en) * 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
GB9822440D0 (en) * 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
AU2437900A (en) * 1999-01-20 2000-08-07 Smithkline Beecham Plc Piperidinylquinolines as protein tyrosine kinase inhibitors
GB9914486D0 (en) * 1999-06-21 1999-08-18 Smithkline Beecham Plc Medicaments
GB9917406D0 (en) * 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
GB9917408D0 (en) * 1999-07-23 1999-09-22 Smithkline Beecham Plc Compounds
US6403610B1 (en) * 1999-09-17 2002-06-11 Aventis Pharma S.A. Quinolylpropylpiperidine derivatives, their preparation and the compositions which comprise them
US6803369B1 (en) * 2000-07-25 2004-10-12 Smithkline Beecham Corporation Compounds and methods for the treatment of neoplastic disease
CN1452619A (zh) * 2000-07-26 2003-10-29 史密斯克莱·比奇曼公司 具有抗细菌活性的氨基哌啶喹啉和它们的氮杂等排的类似物
EP1320529B1 (en) * 2000-09-21 2006-05-24 Smithkline Beecham Plc Quinoline derivatives as antibacterials
US6603005B2 (en) * 2000-11-15 2003-08-05 Aventis Pharma S.A. Heterocyclylalkylpiperidine derivatives, their preparation and compositions containing them
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GB0031088D0 (en) * 2000-12-20 2001-01-31 Smithkline Beecham Plc Medicaments
GB0101577D0 (en) * 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
US6602884B2 (en) * 2001-03-13 2003-08-05 Aventis Pharma S.A. Quinolylpropylpiperidine derivatives, their preparation, and compositions containing them
GB0112834D0 (en) * 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112836D0 (en) * 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
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US7109213B2 (en) * 2002-01-29 2006-09-19 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
US7312212B2 (en) * 2002-01-29 2007-12-25 Glaxo Group Limited Aminopiperidine derivatives
GB0217294D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicaments

Also Published As

Publication number Publication date
ATE344799T1 (de) 2006-11-15
EP1419155B1 (en) 2006-11-08
DE60215951D1 (de) 2006-12-21
WO2003010138A3 (en) 2003-12-04
WO2003010138A2 (en) 2003-02-06
DE60215951T2 (de) 2007-04-26
JP2005504747A (ja) 2005-02-17
US20040198756A1 (en) 2004-10-07
ES2274999T3 (es) 2007-06-01
EP1419155A2 (en) 2004-05-19
GB0118238D0 (en) 2001-09-19

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase