AU2001295531A1 - Antisense oligonucleotides against vanilloid receptor 1 - Google Patents
Antisense oligonucleotides against vanilloid receptor 1Info
- Publication number
- AU2001295531A1 AU2001295531A1 AU2001295531A AU9553101A AU2001295531A1 AU 2001295531 A1 AU2001295531 A1 AU 2001295531A1 AU 2001295531 A AU2001295531 A AU 2001295531A AU 9553101 A AU9553101 A AU 9553101A AU 2001295531 A1 AU2001295531 A1 AU 2001295531A1
- Authority
- AU
- Australia
- Prior art keywords
- antisense oligonucleotides
- vanilloid receptor
- oligonucleotides against
- against vanilloid
- nucleotide constructs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 108020000948 Antisense Oligonucleotides Proteins 0.000 title 1
- 102100029613 Transient receptor potential cation channel subfamily V member 1 Human genes 0.000 title 1
- 108050004388 Transient receptor potential cation channel subfamily V member 1 Proteins 0.000 title 1
- 239000000074 antisense oligonucleotide Substances 0.000 title 1
- 238000012230 antisense oligonucleotides Methods 0.000 title 1
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 230000000692 anti-sense effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229940046166 oligodeoxynucleotide Drugs 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/06—Anti-spasmodics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
- C12N2310/121—Hammerhead
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/323—Chemical structure of the sugar modified ring structure
- C12N2310/3231—Chemical structure of the sugar modified ring structure having an additional ring, e.g. LNA, ENA
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10043674.9 | 2000-09-02 | ||
DE2000143674 DE10043674A1 (de) | 2000-09-02 | 2000-09-02 | Antisense Oligonukleotide |
DE10043702.8 | 2000-09-04 | ||
DE10043702A DE10043702A1 (de) | 2000-09-04 | 2000-09-04 | Antisense Oligonukleotide |
PCT/EP2001/010081 WO2002018407A2 (de) | 2000-09-02 | 2001-08-31 | Antisense oligonukleotide gegen vanilloid rezeptor 1 |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001295531A1 true AU2001295531A1 (en) | 2002-03-13 |
Family
ID=26006931
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001295531A Abandoned AU2001295531A1 (en) | 2000-09-02 | 2001-08-31 | Antisense oligonucleotides against vanilloid receptor 1 |
Country Status (13)
Country | Link |
---|---|
US (2) | US7662948B2 (de) |
EP (1) | EP1313768B1 (de) |
JP (1) | JP2004507263A (de) |
AT (1) | ATE385505T1 (de) |
AU (1) | AU2001295531A1 (de) |
CA (1) | CA2420656A1 (de) |
DE (1) | DE50113568D1 (de) |
ES (1) | ES2300366T3 (de) |
HU (1) | HUP0301805A3 (de) |
MX (1) | MXPA03001627A (de) |
NZ (1) | NZ524894A (de) |
PL (1) | PL366039A1 (de) |
WO (1) | WO2002018407A2 (de) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
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US20030105044A1 (en) * | 2001-10-17 | 2003-06-05 | Isis Pharmaceuticals Inc. | Antisense modulation of matrix metalloproteinase 1 expression |
DK2264172T3 (da) | 2002-04-05 | 2017-11-27 | Roche Innovation Ct Copenhagen As | Oligomerforbindelser til modulering af HIF-1á-ekspression |
DE10322662A1 (de) * | 2002-11-06 | 2004-10-07 | Grünenthal GmbH | Wirksame und stabile DNA-Enzyme |
DE10257421A1 (de) * | 2002-12-09 | 2004-07-08 | Grünenthal GmbH | Regulatorische Elemente im 5'-Bereich des VR1-Gens |
US20040115634A1 (en) * | 2002-12-11 | 2004-06-17 | Isis Pharmaceuticals, Inc. | Modulation of stat 6 expression |
US7480382B2 (en) * | 2003-09-30 | 2009-01-20 | Microsoft Corporation | Image file container |
US9447138B2 (en) | 2004-11-09 | 2016-09-20 | Roche Innovation Center Copenhagen A/S | Potent LNA oligonucleotides for the inhibition of HIF-1a expression |
WO2006050734A2 (en) * | 2004-11-09 | 2006-05-18 | Santaris Pharma A/S | Potent lna oligonucleotides for the inhibition of hif-1a expression |
US8288354B2 (en) | 2005-12-28 | 2012-10-16 | The Scripps Research Institute | Natural antisense and non-coding RNA transcripts as drug targets |
EP2352830B1 (de) * | 2008-10-03 | 2019-01-16 | CuRNA, Inc. | Behandlung von krankheiten in verbindung mit apolipoprotein a1 durch hemmung eines natürlichen antisense-transkripts gegen apolipoprotein a1 |
WO2010065792A2 (en) | 2008-12-04 | 2010-06-10 | Curna, Inc. | Treatment of erythropoietin (epo) related diseases by inhibition of natural antisense transcript to epo |
ES2600781T3 (es) * | 2008-12-04 | 2017-02-10 | Curna, Inc. | Tratamiento para enfermedades relacionadas con el factor de crecimiento del endotelio vascular (vegf) mediante la inhibición de transcritos antisentido naturales de vegf |
EP2370582B1 (de) | 2008-12-04 | 2017-05-10 | CuRNA, Inc. | Behandlung von tumorsuppressorgen-bedingten erkrankungen mittels hemmung des natürlichen antisense-transkripts gegen das gen |
ES2762610T3 (es) | 2009-02-12 | 2020-05-25 | Curna Inc | Tratamiento de enfermedades relacionadas con el factor neurotrófico derivado de cerebro (BDNF) por inhibición de transcrito antisentido natural para BDNF |
US9464287B2 (en) | 2009-03-16 | 2016-10-11 | Curna, Inc. | Treatment of nuclear factor (erythroid-derived 2)-like 2 (NRF2) related diseases by inhibition of natural antisense transcript to NRF2 |
CN102549159B (zh) | 2009-03-17 | 2016-08-10 | 库尔纳公司 | 通过抑制针对δ样1同源物(DLK1)的天然反义转录物来治疗DLK1相关的疾病 |
CN102803492B (zh) | 2009-05-06 | 2016-06-29 | 库尔纳公司 | 通过抑制针对三重四脯氨酸(ttp)的天然反义转录物来治疗ttp相关疾病 |
CN103223177B (zh) | 2009-05-06 | 2016-08-10 | 库尔纳公司 | 通过针对脂质转运和代谢基因的天然反义转录物的抑制治疗脂质转运和代谢基因相关疾病 |
CA3185821A1 (en) | 2009-05-08 | 2010-11-11 | Curna, Inc. | Treatment of dystrophin family related diseases by inhibition of natural antisense transcript to dmd family |
EP2432881B1 (de) | 2009-05-18 | 2017-11-15 | CuRNA, Inc. | Behandlung von krankheiten im zusammenhang mit dem reprogrammierungsfaktor durch hemmung des natürlichen antisense-transkripts zu einem reprogrammierungsfaktor |
CA2762987A1 (en) | 2009-05-22 | 2010-11-25 | Joseph Collard | Treatment of transcription factor e3 (tfe3) and insulin receptor substrate 2 (irs2) related diseases by inhibition of natural antisense transcript to tfe3 |
JP5960049B2 (ja) | 2009-05-28 | 2016-08-02 | クルナ・インコーポレーテッド | 抗ウイルス遺伝子に対する天然アンチセンス転写物の抑制による抗ウイルス遺伝子関連疾患の治療 |
JP6128846B2 (ja) | 2009-06-16 | 2017-05-17 | クルナ・インコーポレーテッド | パラオキソナーゼ(pon1)に対する天然アンチセンス転写物の抑制によるpon1遺伝子関連疾患の治療 |
US20120171170A1 (en) | 2009-06-16 | 2012-07-05 | Opko Curna, Llc | Treatment of collagen gene related diseases by inhibition of natural antisense transcript to a collagen gene |
EP2446036B1 (de) | 2009-06-24 | 2017-03-01 | CuRNA, Inc. | Behandlung von erkrankungen im zusammenhang mit tumornekrose faktor-rezeptor 2 (tnfr2) mittels hemmung des natürlichen antisense-transkripts gegen tnfr2 |
CN102482672B (zh) | 2009-06-26 | 2016-11-09 | 库尔纳公司 | 通过抑制唐氏综合征基因的天然反义转录物治疗唐氏综合征基因相关疾病 |
JP2013500017A (ja) | 2009-07-24 | 2013-01-07 | カッパーアールエヌエー,インコーポレイテッド | サ−チュイン(sirt)への天然アンチセンス転写物の阻止によるサ−チュイン(sirt)関連疾患の治療 |
US8572084B2 (en) * | 2009-07-28 | 2013-10-29 | Fti Consulting, Inc. | System and method for displaying relationships between electronically stored information to provide classification suggestions via nearest neighbor |
CN102762731B (zh) | 2009-08-05 | 2018-06-22 | 库尔纳公司 | 通过抑制针对胰岛素基因(ins)的天然反义转录物来治疗胰岛素基因(ins)相关的疾病 |
US9044493B2 (en) | 2009-08-11 | 2015-06-02 | Curna, Inc. | Treatment of Adiponectin related diseases by inhibition of natural antisense transcript to an Adiponectin |
WO2011022606A2 (en) | 2009-08-21 | 2011-02-24 | Curna, Inc. | Treatment of 'c terminus of hsp70-interacting protein' (chip) related diseases by inhibition of natural antisense transcript to chip |
WO2011031482A2 (en) | 2009-08-25 | 2011-03-17 | Curna, Inc. | Treatment of 'iq motif containing gtpase activating protein' (iqgap) related diseases by inhibition of natural antisense transcript to iqgap |
EP2480669B1 (de) | 2009-09-25 | 2017-11-08 | CuRNA, Inc. | Behandlung filaggrin (flg)-assoziierter erkrankungen durch modulierung der flg-expression und -aktivität |
RU2639550C2 (ru) | 2009-12-16 | 2017-12-21 | Курна, Инк. | Лечение заболеваний, связанных с сайт-1 мембраносвязанной пептидазой транскрипционных факторов (mbtps1), путем ингибирования природного антисмыслового транскрипта к mbtps1 |
CN102781480B (zh) | 2009-12-23 | 2018-07-27 | 库尔纳公司 | 通过抑制解偶联蛋白2(ucp2)的天然反义转录物而治疗ucp2相关疾病 |
KR101891352B1 (ko) | 2009-12-23 | 2018-08-24 | 큐알엔에이, 인크. | 간세포 성장 인자(hgf)에 대한 천연 안티센스 전사체의 억제에 의한 hgf 관련 질환의 치료 |
CA2785173A1 (en) | 2009-12-29 | 2011-07-28 | Curna, Inc. | Treatment of nuclear respiratory factor 1 (nrf1) related diseases by inhibition of natural antisense transcript to nrf1 |
WO2011090741A2 (en) | 2009-12-29 | 2011-07-28 | Opko Curna, Llc | TREATMENT OF TUMOR PROTEIN 63 (p63) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO p63 |
US20120289583A1 (en) | 2009-12-31 | 2012-11-15 | Curna, Inc. | Treatment of insulin receptor substrate 2 (irs2) related diseases by inhibition of natural antisense transcript to irs2 and transcription factor e3 (tfe3) |
US8946181B2 (en) | 2010-01-04 | 2015-02-03 | Curna, Inc. | Treatment of interferon regulatory factor 8 (IRF8) related diseases by inhibition of natural antisense transcript to IRF8 |
EP2521785B1 (de) | 2010-01-06 | 2022-03-09 | CuRNA, Inc. | Inhibition des natürlichen antisense-transkripts des pankreasentwicklungsgens zur verwendung in der behandlung von pankreatischen entwicklungsgenbezogenen krankheiten |
US9200277B2 (en) | 2010-01-11 | 2015-12-01 | Curna, Inc. | Treatment of sex hormone binding globulin (SHBG) related diseases by inhibition of natural antisense transcript to SHBG |
CA2786568A1 (en) | 2010-01-25 | 2011-07-28 | Curna, Inc. | Treatment of rnase h1 related diseases by inhibition of natural antisense transcript to rnase h1 |
JP5976548B2 (ja) | 2010-02-22 | 2016-08-23 | カッパーアールエヌエー,インコーポレイテッド | Pycr1に対する天然アンチセンス転写物の阻害によるピロリン−5−カルボン酸レダクターゼ1(pycr1)関連疾患の治療 |
CA2795145C (en) | 2010-04-02 | 2019-01-22 | Curna, Inc. | Treatment of colony-stimulating factor 3 (csf3) related diseases by inhibition of natural antisense transcript to csf3 |
CA2795281A1 (en) | 2010-04-09 | 2011-10-13 | Curna, Inc. | Treatment of fibroblast growth factor 21 (fgf21) related diseases by inhibition of natural antisense transcript to fgf21 |
RU2693462C2 (ru) | 2010-05-03 | 2019-07-03 | Курна, Инк. | Лечение заболеваний, связанных с сиртуином (sirt), путем ингибирования природного антисмыслового транскрипта к сиртуину (sirt) |
TWI531370B (zh) | 2010-05-14 | 2016-05-01 | 可娜公司 | 藉由抑制par4天然反股轉錄本治療par4相關疾病 |
JP5917497B2 (ja) | 2010-05-26 | 2016-05-18 | カッパーアールエヌエー,インコーポレイテッド | メチオニンスルホキシドレダクターゼa(msra)に対する天然アンチセンス転写物の阻害によるmsra関連疾患の治療 |
RU2585229C2 (ru) | 2010-05-26 | 2016-05-27 | Курна, Инк. | Лечение заболеваний, связанных с атональным гомологом 1 (атон1), путем ингибирования природного антисмыслового транскрипта гена атон1 |
DK2585596T3 (da) | 2010-06-23 | 2021-04-06 | Curna Inc | Behandling af spændingsreguleret natriumkanal-alpha-underenhed (scna)-relaterede sygdomme ved inhibering af naturligt antisense-transkript til scna |
JP5998131B2 (ja) | 2010-07-14 | 2016-09-28 | カッパーアールエヌエー,インコーポレイテッド | Discslargehomolog(dlg)dlg1への天然アンチセンス転写物の阻害によるdlg関連疾患の治療 |
EP2625274B1 (de) | 2010-10-06 | 2017-07-19 | CuRNA, Inc. | Behandlung sialidase-4-(neu4)-vermittelter erkrankungen durch hemmung des natürlichen antisense-transkripts gegen neu4 |
US9222088B2 (en) | 2010-10-22 | 2015-12-29 | Curna, Inc. | Treatment of alpha-L-iduronidase (IDUA) related diseases by inhibition of natural antisense transcript to IDUA |
US10000752B2 (en) | 2010-11-18 | 2018-06-19 | Curna, Inc. | Antagonat compositions and methods of use |
RU2608493C2 (ru) | 2010-11-23 | 2017-01-18 | Курна, Инк. | Лечение заболеваний, связанных с nanog, путем ингибирования природного антисмыслового транскрипта nanog |
TWI678375B (zh) | 2011-06-09 | 2019-12-01 | 可娜公司 | 藉由抑制共濟蛋白(frataxin,fxn)之天然反股轉錄本治療fxn相關疾病 |
CN103874486A (zh) | 2011-09-06 | 2014-06-18 | 库尔纳公司 | 用小分子治疗与电压门控钠通道的α亚基(SCNxA)相关的疾病 |
HUE040179T2 (hu) | 2012-03-15 | 2019-02-28 | Curna Inc | Agyi eredetû neutrotróf faktorral (Brain-derived neurotrophic factor, BDNF) összefüggõ betegségek kezelése a BDNF-fel kapcsolatos természetes antiszensz transzkriptumok gátlása révén |
MX2016012903A (es) | 2014-04-01 | 2016-12-07 | Procter & Gamble | Metodos y composiciones para la modificacion de la percepcion sensorial. |
GB201410693D0 (en) | 2014-06-16 | 2014-07-30 | Univ Southampton | Splicing modulation |
WO2016054615A2 (en) | 2014-10-03 | 2016-04-07 | Cold Spring Harbor Laboratory | Targeted augmentation of nuclear gene output |
KR20220105174A (ko) | 2015-10-09 | 2022-07-26 | 유니버시티 오브 사우스앰톤 | 유전자 발현의 조절 및 탈조절된 단백질 발현의 스크리닝 |
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JP7049248B2 (ja) | 2015-12-14 | 2022-04-06 | コールド スプリング ハーバー ラボラトリー | 常染色体優性精神遅滞-5とドラベ症候群の処置のためのアンチセンスオリゴマー |
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WO1999009140A1 (en) * | 1997-08-20 | 1999-02-25 | The Regents Of The University Of California | Nucleic acid sequences encoding capsaicin receptor and capsaicin receptor-related polypeptides and uses thereof |
EP1047711B1 (de) * | 1998-01-22 | 2003-08-20 | The Regents of the University of California | Nukleinsäuresequenzen, welche für capsaicin-rezeptoren kodieren |
EP0943683A1 (de) | 1998-03-10 | 1999-09-22 | Smithkline Beecham Plc | Menschliches Vanilloid Rezeptorhomolog Vanilrep1 |
GB9822124D0 (en) * | 1998-10-09 | 1998-12-02 | Univ London | Ion channels |
JP2002531069A (ja) * | 1998-11-13 | 2002-09-24 | ミレニアム・フアーマシユーチカルズ・インコーポレーテツド | タンパク質のカプサイシン/バニロイド受容体ファミリーの新規メンバー及びそれらの使用 |
GB9826359D0 (en) | 1998-12-01 | 1999-01-27 | Glaxo Group Ltd | Novel receptors |
GB9827016D0 (en) | 1998-12-08 | 1999-02-03 | Merck Sharp & Dohme | Receptor protein |
WO2000063415A1 (en) | 1999-04-15 | 2000-10-26 | Ortho-Mcneil Pharmaceutical, Inc. | Dna encoding the human vanilloid receptor vr1 |
US6482611B1 (en) * | 1999-09-23 | 2002-11-19 | Neurogen Corporation | Human capsaicin receptor and uses thereof |
US20040259092A1 (en) * | 2001-08-27 | 2004-12-23 | Carmen Barske | Nogo receptor homologues and their use |
-
2001
- 2001-08-31 AT AT01976176T patent/ATE385505T1/de active
- 2001-08-31 NZ NZ524894A patent/NZ524894A/en unknown
- 2001-08-31 HU HU0301805A patent/HUP0301805A3/hu unknown
- 2001-08-31 AU AU2001295531A patent/AU2001295531A1/en not_active Abandoned
- 2001-08-31 PL PL01366039A patent/PL366039A1/xx not_active Application Discontinuation
- 2001-08-31 MX MXPA03001627A patent/MXPA03001627A/es unknown
- 2001-08-31 CA CA002420656A patent/CA2420656A1/en not_active Abandoned
- 2001-08-31 DE DE50113568T patent/DE50113568D1/de not_active Expired - Lifetime
- 2001-08-31 EP EP01976176A patent/EP1313768B1/de not_active Expired - Lifetime
- 2001-08-31 ES ES01976176T patent/ES2300366T3/es not_active Expired - Lifetime
- 2001-08-31 WO PCT/EP2001/010081 patent/WO2002018407A2/de active IP Right Grant
- 2001-08-31 JP JP2002523921A patent/JP2004507263A/ja active Pending
-
2003
- 2003-03-03 US US10/376,341 patent/US7662948B2/en not_active Expired - Fee Related
-
2009
- 2009-12-23 US US12/645,625 patent/US20100316615A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1313768A2 (de) | 2003-05-28 |
ATE385505T1 (de) | 2008-02-15 |
ES2300366T3 (es) | 2008-06-16 |
DE50113568D1 (de) | 2008-03-20 |
JP2004507263A (ja) | 2004-03-11 |
WO2002018407A3 (de) | 2002-10-03 |
US7662948B2 (en) | 2010-02-16 |
US20040002473A1 (en) | 2004-01-01 |
HUP0301805A2 (hu) | 2003-08-28 |
CA2420656A1 (en) | 2003-02-26 |
NZ524894A (en) | 2005-03-24 |
PL366039A1 (en) | 2005-01-24 |
HUP0301805A3 (en) | 2005-12-28 |
MXPA03001627A (es) | 2003-06-24 |
EP1313768B1 (de) | 2008-02-06 |
WO2002018407A9 (de) | 2003-05-15 |
WO2002018407A2 (de) | 2002-03-07 |
US20100316615A1 (en) | 2010-12-16 |
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MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |