AU2001239913B2 - Method of treating cancer with anti-neurotrophin agents - Google Patents
Method of treating cancer with anti-neurotrophin agents Download PDFInfo
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- AU2001239913B2 AU2001239913B2 AU2001239913A AU2001239913A AU2001239913B2 AU 2001239913 B2 AU2001239913 B2 AU 2001239913B2 AU 2001239913 A AU2001239913 A AU 2001239913A AU 2001239913 A AU2001239913 A AU 2001239913A AU 2001239913 B2 AU2001239913 B2 AU 2001239913B2
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18594300P | 2000-02-29 | 2000-02-29 | |
| US60/185,943 | 2000-02-29 | ||
| US09/793,850 US6548062B2 (en) | 2000-02-29 | 2001-02-27 | Method of treating cancer with anti-neurotrophin agents |
| US09/793,850 | 2001-02-27 | ||
| PCT/US2001/006266 WO2001064247A2 (en) | 2000-02-29 | 2001-02-28 | Method of treating cancer with anti-neurotrophin agents |
Publications (2)
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|---|---|
| AU2001239913A1 AU2001239913A1 (en) | 2001-11-22 |
| AU2001239913B2 true AU2001239913B2 (en) | 2005-12-08 |
Family
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| AU2001239913A Ceased AU2001239913B2 (en) | 2000-02-29 | 2001-02-28 | Method of treating cancer with anti-neurotrophin agents |
| AU3991301A Pending AU3991301A (en) | 2000-02-29 | 2001-02-28 | Method of treating cancer with anti-neurotrophin agents |
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| AU3991301A Pending AU3991301A (en) | 2000-02-29 | 2001-02-28 | Method of treating cancer with anti-neurotrophin agents |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6548062B2 (enExample) |
| EP (1) | EP1261372B1 (enExample) |
| JP (1) | JP2003525253A (enExample) |
| CN (1) | CN1227033C (enExample) |
| AT (1) | ATE361100T1 (enExample) |
| AU (2) | AU2001239913B2 (enExample) |
| CA (1) | CA2401604C (enExample) |
| DE (1) | DE60128208T2 (enExample) |
| ES (1) | ES2286110T3 (enExample) |
| HK (1) | HK1049961B (enExample) |
| MX (1) | MXPA02008465A (enExample) |
| NZ (1) | NZ521165A (enExample) |
| WO (1) | WO2001064247A2 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100081197A1 (en) * | 1997-08-14 | 2010-04-01 | Sylvie Roux | In vivo modulation of neuronal transport |
| JP3773733B2 (ja) * | 2000-01-13 | 2006-05-10 | 松下電器産業株式会社 | 陰極線管 |
| FR2807660A1 (fr) * | 2000-04-13 | 2001-10-19 | Warner Lambert Co | Utilisation d'antagonistes du ngf pour la prevention ou le traitement de douleurs viscerales chroniques |
| CN1684708A (zh) * | 2001-05-30 | 2005-10-19 | 基因技术股份有限公司 | 抗ngf抗体用于治疗各种疾病 |
| US20060147450A1 (en) * | 2002-10-04 | 2006-07-06 | Shelton David L | Methods for treating cardiac arrhythmia and preventing death due to cardiac arrhythmia using ngf antagonists |
| UA80447C2 (en) | 2002-10-08 | 2007-09-25 | Methods for treating pain by administering nerve growth factor antagonist and opioid analgesic | |
| WO2005000194A2 (en) | 2002-10-08 | 2005-01-06 | Rinat Neuroscience Corp. | Methods for treating post-surgical pain by administering an anti-nerve growth factor antagonist antibody and compositions containing the same |
| JP4584713B2 (ja) * | 2002-10-08 | 2010-11-24 | ライナット ニューロサイエンス コーポレイション | 神経成長因子アンタゴニストを投与することによって術後疼痛を処置するための方法および神経成長因子アンタゴニストを含有する組成物 |
| FR2846426B1 (fr) * | 2002-10-28 | 2004-12-10 | Bio Merieux | Procede de dosage du ngf pour le diagnostic in vitro du cancer du sein et utilisation en therapie |
| US9498530B2 (en) | 2002-12-24 | 2016-11-22 | Rinat Neuroscience Corp. | Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same |
| CN101014364B (zh) * | 2002-12-24 | 2012-01-18 | 里纳特神经系统学公司 | 抗ngf抗体及其使用方法 |
| US7569364B2 (en) | 2002-12-24 | 2009-08-04 | Pfizer Inc. | Anti-NGF antibodies and methods using same |
| PL379983A1 (pl) * | 2003-02-19 | 2006-11-27 | Rinat Neuroscience Corp. | Sposoby leczenia bólu polegające na podaniu antagonisty czynnika wzrostu nerwów i niesteroidowego leku przeciwzapalnego oraz zawierające je kompozycje |
| US20050043215A1 (en) * | 2003-02-19 | 2005-02-24 | Tamara Minko | Complex drug delivery composition and method for treating cancer |
| EA013614B1 (ru) * | 2003-07-15 | 2010-06-30 | Амджен Инк. | Изолированное антитело к фактору роста нервов (ngf) и способы его применения |
| ES2616337T3 (es) * | 2003-12-12 | 2017-06-12 | Government Of The United States Of America, As Repr. By The Secr. Of The Dept. Of Health And Human Services And His Successors | Un epítopo de linfocito T citotóxico humano y su epítopo agonista del número no variable de secuencias de repetición en tándem de MUC-1 |
| ITRM20030601A1 (it) * | 2003-12-24 | 2005-06-25 | Lay Line Genomics Spa | Metodo per l'umanizzazione di anticorpi e anticorpi umanizzati con esso ottenuti. |
| EP3372614B1 (en) * | 2004-04-07 | 2022-06-08 | Rinat Neuroscience Corp. | Methods for treating bone cancer pain by administering a nerve growth factor antagonist |
| ME00226B (me) | 2004-07-15 | 2011-02-10 | Medarex Llc | Humana anti-ngf neutrališuća antitijela kao selektivni inhibitori ngf signalne kaskade |
| US20090196850A1 (en) | 2005-01-06 | 2009-08-06 | Novo Nordisk A/S | Anti-Kir Combination Treatments and Methods |
| NZ556157A (en) | 2005-01-24 | 2009-09-25 | Elan Pharma Int Ltd | Specific binding members for NGF |
| ITRM20050290A1 (it) * | 2005-06-07 | 2006-12-08 | Lay Line Genomics Spa | Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato. |
| FR2896881B1 (fr) * | 2006-01-31 | 2008-04-18 | Biomerieux Sa | Procede de dosage du prongf pour le diagnostic in vitro du cancer du sein et utilisation du prongf en therapie |
| US8309088B2 (en) | 2007-08-10 | 2012-11-13 | Regeneron Pharmaceuticals, Inc. | Method of treating osteoarthritis with an antibody to NGF |
| RS53661B1 (sr) | 2007-08-10 | 2015-04-30 | Regeneron Pharmaceuticals, Inc. | Humana antitela visokog afiniteta prema humanom nervnom faktoru rasta |
| US20110229485A1 (en) * | 2008-05-21 | 2011-09-22 | Centre National De La Recherche Scientfique (Cnrs) | Inhibition of the nt-3:trkc bound and its application to the treatment of cancer such as neuroblastoma |
| WO2009150623A1 (en) | 2008-06-13 | 2009-12-17 | Pfizer Inc | Treatment of chronic prostatitis |
| JP2012515158A (ja) | 2009-01-12 | 2012-07-05 | 武田薬品工業株式会社 | 癌の予防・治療剤 |
| EA201190115A1 (ru) | 2009-01-24 | 2012-02-28 | ФИТОФАРМ ПиЭлСи | Лечение расстройств, опосредованных нейротрофическим фактором |
| US8435523B2 (en) * | 2009-05-04 | 2013-05-07 | Abbott Research B.V. | Antibodies against nerve growth factor (NGF) with enhanced in vivo stability |
| EP2547365A1 (en) | 2010-03-17 | 2013-01-23 | Abbott Research B.V. | Anti-nerve growth factor (ngf) antibody compositions |
| CA2808577C (en) | 2010-08-19 | 2018-09-25 | Abbott Laboratories | Anti-ngf antibodies and their use |
| JP6105838B2 (ja) * | 2010-08-24 | 2017-03-29 | 国立大学法人 岡山大学 | 疼痛の治療剤 |
| US9078878B2 (en) | 2010-12-01 | 2015-07-14 | Alderbio Holdings Llc | Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75 |
| WO2012075340A2 (en) | 2010-12-01 | 2012-06-07 | Alderbio Holdings Llc | Anti-ngf compositions and use thereof |
| US9067988B2 (en) | 2010-12-01 | 2015-06-30 | Alderbio Holdings Llc | Methods of preventing or treating pain using anti-NGF antibodies |
| US9884909B2 (en) | 2010-12-01 | 2018-02-06 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
| US9539324B2 (en) | 2010-12-01 | 2017-01-10 | Alderbio Holdings, Llc | Methods of preventing inflammation and treating pain using anti-NGF compositions |
| US11214610B2 (en) | 2010-12-01 | 2022-01-04 | H. Lundbeck A/S | High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris |
| US8926978B2 (en) | 2011-10-25 | 2015-01-06 | Anaptysbio, Inc. | Antibodies directed against nerve growth factor (NGF) |
| AU2013271564A1 (en) | 2012-06-06 | 2014-12-04 | Zoetis Services Llc | Caninized anti-NGF antibodies and methods thereof |
| EP2859019B1 (en) | 2012-06-08 | 2018-02-21 | Glenmark Pharmaceuticals S.A. | Humanized anti-trka antibodies with amino acid substitutions |
| TWI703158B (zh) * | 2015-09-18 | 2020-09-01 | 美商希佛隆公司 | 特異性結合tl1a之抗體 |
| CA3093772C (en) | 2018-03-12 | 2024-04-16 | Zoetis Services Llc | Anti-ngf antibodies and methods thereof |
| MX2024007088A (es) | 2021-12-16 | 2024-08-22 | Intervet Int Bv | Anticuerpos caninizados contra el ngf humano. |
| EP4514998A1 (en) | 2022-04-27 | 2025-03-05 | Regeneron Pharmaceuticals, Inc. | Treatment of arthropathy based upon stratification of osteoarthritis polygenic risk score |
| US20240310383A1 (en) | 2023-03-17 | 2024-09-19 | Regeneron Pharmaceuticals, Inc. | Proteomic Risk Score For Osteoarthritis (OA) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994006935A1 (en) * | 1992-09-11 | 1994-03-31 | Cephalon, Inc. | A method for the detection and treatment of prostate disease |
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| CN1073264A (zh) | 1991-11-12 | 1993-06-16 | 里珍纳龙药品有限公司 | 基于组织的特定的nt-3表达与受体结合的治疗和诊断方法 |
| US5844092A (en) * | 1994-03-18 | 1998-12-01 | Genentech, Inc. | Human TRK receptors and neurotrophic factor inhibitors |
| EP0753013A1 (en) * | 1994-03-29 | 1997-01-15 | Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften E.V. | Neurotrophin-6: a new member of the neurotrophin family |
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- 2001-02-28 CN CNB018058108A patent/CN1227033C/zh not_active Expired - Fee Related
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- 2001-02-28 EP EP01914537A patent/EP1261372B1/en not_active Expired - Lifetime
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- 2001-02-28 ES ES01914537T patent/ES2286110T3/es not_active Expired - Lifetime
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994006935A1 (en) * | 1992-09-11 | 1994-03-31 | Cephalon, Inc. | A method for the detection and treatment of prostate disease |
Also Published As
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| HK1049961A1 (en) | 2003-06-06 |
| HK1049961B (en) | 2007-09-14 |
| ES2286110T3 (es) | 2007-12-01 |
| CA2401604A1 (en) | 2001-09-07 |
| MXPA02008465A (es) | 2003-03-10 |
| CA2401604C (en) | 2011-05-24 |
| WO2001064247A3 (en) | 2002-02-14 |
| EP1261372A2 (en) | 2002-12-04 |
| JP2003525253A (ja) | 2003-08-26 |
| NZ521165A (en) | 2004-08-27 |
| US20010046959A1 (en) | 2001-11-29 |
| EP1261372B1 (en) | 2007-05-02 |
| CN1227033C (zh) | 2005-11-16 |
| ATE361100T1 (de) | 2007-05-15 |
| DE60128208D1 (de) | 2007-06-14 |
| CN1420785A (zh) | 2003-05-28 |
| DE60128208T2 (de) | 2008-01-10 |
| US6548062B2 (en) | 2003-04-15 |
| AU3991301A (en) | 2001-09-12 |
| WO2001064247A2 (en) | 2001-09-07 |
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