ATE9820T1 - Verfahren zur enzymatischen substitution der b-30-aminosaeure in den insulinen. - Google Patents

Verfahren zur enzymatischen substitution der b-30-aminosaeure in den insulinen.

Info

Publication number
ATE9820T1
ATE9820T1 AT81303383T AT81303383T ATE9820T1 AT E9820 T1 ATE9820 T1 AT E9820T1 AT 81303383 T AT81303383 T AT 81303383T AT 81303383 T AT81303383 T AT 81303383T AT E9820 T1 ATE9820 T1 AT E9820T1
Authority
AT
Austria
Prior art keywords
ins
amino acid
insulin
ser
insulins
Prior art date
Application number
AT81303383T
Other languages
English (en)
Inventor
Klaus Breddam
Fred C/O Dept. Of Health And H Widmer
Health
Jack Taaning Johansen
Original Assignee
De Forenede Bryggerier A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by De Forenede Bryggerier A/S filed Critical De Forenede Bryggerier A/S
Application granted granted Critical
Publication of ATE9820T1 publication Critical patent/ATE9820T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT81303383T 1980-07-24 1981-07-23 Verfahren zur enzymatischen substitution der b-30-aminosaeure in den insulinen. ATE9820T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK319780A DK319780A (da) 1980-07-24 1980-07-24 Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
EP81303383A EP0045187B1 (de) 1980-07-24 1981-07-23 Verfahren zur enzymatischen Substitution der B-30-Aminosäure in den Insulinen

Publications (1)

Publication Number Publication Date
ATE9820T1 true ATE9820T1 (de) 1984-10-15

Family

ID=8120166

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81303383T ATE9820T1 (de) 1980-07-24 1981-07-23 Verfahren zur enzymatischen substitution der b-30-aminosaeure in den insulinen.

Country Status (14)

Country Link
US (1) US4645740A (de)
EP (1) EP0045187B1 (de)
JP (1) JPS642360B2 (de)
AT (1) ATE9820T1 (de)
AU (1) AU543687B2 (de)
CA (1) CA1175372A (de)
DE (1) DE3166608D1 (de)
DK (1) DK319780A (de)
ES (2) ES504462A0 (de)
HU (1) HU185668B (de)
IE (1) IE51620B1 (de)
SU (2) SU1554766A3 (de)
WO (1) WO1982000301A1 (de)
ZA (1) ZA815066B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3101382A1 (de) * 1981-01-17 1982-09-02 Hoechst Ag, 6000 Frankfurt "verfahren zur herstellung von humanisulin oder dessen derivaten aus schweineinsulin oder dessen derivaten"
EP0088117B1 (de) * 1981-09-15 1986-09-24 Nordisk Insulinlaboratorium Verfahren zur herstellung von menschlichem insulin oder b-30-estern davon
AU8457482A (en) * 1981-05-20 1982-12-07 Nordisk Insulinlaboratorium A process for the preparation of insulin derivatives
DK353781A (da) * 1981-08-10 1983-02-11 Novo Industri As Fremgangsmaade til fremstilling af insulinderivater
WO1983002772A1 (en) * 1982-02-08 1983-08-18 Robin Ewart Offord An improved method for preparing human insulin from non-human insulin
DE3209184A1 (de) * 1982-03-13 1983-09-15 Hoechst Ag, 6230 Frankfurt Verfahren zur umwandlung von praeproinsulinanaloga zu insulinen
NL8201650A (nl) * 1982-04-21 1983-11-16 Akzo Nv Semisynthetische bereiding van humane insuline.
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DE3333640A1 (de) * 1983-09-17 1985-04-25 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
DK220890D0 (da) * 1990-09-14 1990-09-14 Ole Buchardt Fremgangsmaade til fremstilling af c-terminalt amiderede peptider
US5580751A (en) * 1990-09-14 1996-12-03 Carlsberg A/S Process for the preparation of C-terminally amidated peptides
WO1995007931A1 (en) * 1993-09-17 1995-03-23 Novo Nordisk A/S Acylated insulin
US6869930B1 (en) * 1993-09-17 2005-03-22 Novo Nordisk A/S Acylated insulin
US6011007A (en) * 1993-09-17 2000-01-04 Novo Nordisk A/S Acylated insulin
WO1998004731A1 (fr) * 1996-07-25 1998-02-05 Firma 'nika-Universal' Techniques binaires de production de peptides biologiquement actifs
US6323311B1 (en) 1999-09-22 2001-11-27 University Of Utah Research Foundation Synthesis of insulin derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3276961A (en) * 1963-04-08 1966-10-04 Squibb & Sons Inc Process for preparing human insulin
US4182654A (en) * 1974-09-18 1980-01-08 Pierce Chemical Company Production of polypeptides using polynucleotides
JPS6339237B2 (de) * 1979-04-06 1988-08-04 Karuruberugu Baiotekunorojii Ltd As
JPS55138391A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd New synthetic method of peptide derivative
NO153061C (no) * 1979-04-13 1986-01-08 Shionogi & Co Fremgangsmaate for fremstilling av et b30-threonininsulin
IE50892B1 (en) * 1980-02-11 1986-08-06 Novo Industri As Process for preparing insulin esters

Also Published As

Publication number Publication date
SU1554766A3 (ru) 1990-03-30
IE811660L (en) 1982-01-24
AU7450881A (en) 1982-02-16
IE51620B1 (en) 1987-01-21
DE3166608D1 (en) 1984-11-15
ES8306182A1 (es) 1983-06-01
EP0045187A1 (de) 1982-02-03
JPS57501161A (de) 1982-07-08
SU1611217A3 (ru) 1990-11-30
US4645740A (en) 1987-02-24
WO1982000301A1 (en) 1982-02-04
HU185668B (en) 1985-03-28
ES8300858A1 (es) 1982-12-01
ES514463A0 (es) 1983-06-01
AU543687B2 (en) 1985-04-26
EP0045187B1 (de) 1984-10-10
DK319780A (da) 1982-01-25
ES504462A0 (es) 1982-12-01
ZA815066B (en) 1983-03-30
JPS642360B2 (de) 1989-01-17
CA1175372A (en) 1984-10-02

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee