ATE42203T1 - Semi-synthetisches verfahren zur herstellung von insulin. - Google Patents

Semi-synthetisches verfahren zur herstellung von insulin.

Info

Publication number
ATE42203T1
ATE42203T1 AT83200530T AT83200530T ATE42203T1 AT E42203 T1 ATE42203 T1 AT E42203T1 AT 83200530 T AT83200530 T AT 83200530T AT 83200530 T AT83200530 T AT 83200530T AT E42203 T1 ATE42203 T1 AT E42203T1
Authority
AT
Austria
Prior art keywords
semi
ester
human insulin
insulin
manufacture
Prior art date
Application number
AT83200530T
Other languages
English (en)
Inventor
Dedem Gijsbert Willem Kare Van
Houdenhoven Francois Egber Van
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Application granted granted Critical
Publication of ATE42203T1 publication Critical patent/ATE42203T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT83200530T 1982-04-21 1983-04-14 Semi-synthetisches verfahren zur herstellung von insulin. ATE42203T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8201650A NL8201650A (nl) 1982-04-21 1982-04-21 Semisynthetische bereiding van humane insuline.
EP83200530A EP0092280B1 (de) 1982-04-21 1983-04-14 Semi-synthetisches Verfahren zur Herstellung von Insulin

Publications (1)

Publication Number Publication Date
ATE42203T1 true ATE42203T1 (de) 1989-05-15

Family

ID=19839621

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83200530T ATE42203T1 (de) 1982-04-21 1983-04-14 Semi-synthetisches verfahren zur herstellung von insulin.

Country Status (15)

Country Link
US (1) US4840897A (de)
EP (1) EP0092280B1 (de)
JP (2) JPS58189149A (de)
AT (1) ATE42203T1 (de)
AU (1) AU554050B2 (de)
CA (1) CA1202587A (de)
DE (1) DE3379640D1 (de)
DK (1) DK173007B1 (de)
ES (1) ES8405760A1 (de)
HU (1) HU189268B (de)
IL (1) IL68397A (de)
NL (1) NL8201650A (de)
PL (1) PL143571B1 (de)
SU (1) SU1232148A3 (de)
ZA (1) ZA832602B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3326473A1 (de) * 1983-07-22 1985-01-31 Hoechst Ag, 6230 Frankfurt Pharmazeutisches mittel zur behandlung des diabetes mellitus
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DE3333640A1 (de) * 1983-09-17 1985-04-25 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung
DK309184D0 (da) * 1984-06-25 1984-06-25 Nordisk Insulinlab Fremgangsmaade til isolering af insulin eller insulinlignende materiale fra en fermenteringsvaeske
CN113956326A (zh) * 2021-09-15 2022-01-21 河南工业大学 一种短肽单体，结构自愈型肽基水凝胶及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3276961A (en) * 1963-04-08 1966-10-04 Squibb & Sons Inc Process for preparing human insulin
US4182654A (en) * 1974-09-18 1980-01-08 Pierce Chemical Company Production of polypeptides using polynucleotides
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
EP0017938B1 (de) * 1979-04-13 1983-08-03 Shionogi & Co., Ltd. Verfahren zur Herstellung von B30-Threonin-Insulin
JPS55138391A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd New synthetic method of peptide derivative
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
US4343898A (en) * 1980-02-11 1982-08-10 Novo Industri A/S Process for preparing esters of human insulin
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
DE3327928A1 (de) * 1983-08-03 1985-02-21 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten

Also Published As

Publication number Publication date
AU1355483A (en) 1983-10-27
IL68397A (en) 1986-01-31
HU189268B (en) 1986-06-30
DK161683A (da) 1983-10-22
DE3379640D1 (en) 1989-05-24
IL68397A0 (en) 1983-07-31
US4840897A (en) 1989-06-20
CA1202587A (en) 1986-04-01
DK161683D0 (da) 1983-04-13
DK173007B1 (da) 1999-11-08
EP0092280A1 (de) 1983-10-26
SU1232148A3 (ru) 1986-05-15
JPH05339290A (ja) 1993-12-21
ES521674A0 (es) 1984-06-16
ES8405760A1 (es) 1984-06-16
JPH0533993B2 (de) 1993-05-20
EP0092280B1 (de) 1989-04-19
AU554050B2 (en) 1986-08-07
PL143571B1 (en) 1988-02-29
PL241575A1 (en) 1983-12-19
JPS58189149A (ja) 1983-11-04
NL8201650A (nl) 1983-11-16
JPH0735399B2 (ja) 1995-04-19
ZA832602B (en) 1984-01-25

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time