US6406713B1
(en)
|
1987-03-05 |
2002-06-18 |
The Liposome Company, Inc. |
Methods of preparing low-toxicity drug-lipid complexes
|
US5091188A
(en)
*
|
1990-04-26 |
1992-02-25 |
Haynes Duncan H |
Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
|
US5534502A
(en)
*
|
1990-11-06 |
1996-07-09 |
Nippon Shinyaku Co. Ltd. |
Process for producing fat emulsion
|
JP2653246B2
(ja)
*
|
1990-11-06 |
1997-09-17 |
日本新薬株式会社 |
脂肪乳剤の製法
|
WO1992007571A1
(fr)
*
|
1990-11-06 |
1992-05-14 |
Nippon Shinyaku Co., Ltd. |
Procede de production d'une emulsion grasse
|
DE4131562A1
(de)
*
|
1991-09-18 |
1993-03-25 |
Medac Klinische Spezialpraep |
Arzneistofftraeger aus festen lipidteilchen-feste lipidnanosphaeren (sln)
|
US5319116A
(en)
*
|
1992-02-12 |
1994-06-07 |
Gary Viole |
Lecithin fractions and dilutions, methods for their preparation and pharmacological uses thereof
|
US5336507A
(en)
*
|
1992-12-11 |
1994-08-09 |
Sterling Winthrop Inc. |
Use of charged phospholipids to reduce nanoparticle aggregation
|
DE4244466C2
(de)
*
|
1992-12-24 |
1995-02-23 |
Pharmatech Gmbh |
Verfahren zur Herstellung von Pseudolatices und Mikro- oder Nanopartikeln und deren Verwendung zur Herstellung von pharmazeutischen Präparaten
|
US5393527A
(en)
*
|
1993-01-04 |
1995-02-28 |
Becton, Dickinson And Company |
Stabilized microspheres and methods of preparation
|
US5650156A
(en)
*
|
1993-02-22 |
1997-07-22 |
Vivorx Pharmaceuticals, Inc. |
Methods for in vivo delivery of nutriceuticals and compositions useful therefor
|
US5997904A
(en)
*
|
1993-02-22 |
1999-12-07 |
American Bioscience, Inc. |
Total nutrient admixtures as stable multicomponent liquids or dry powders and methods for the preparation thereof
|
US6753006B1
(en)
|
1993-02-22 |
2004-06-22 |
American Bioscience, Inc. |
Paclitaxel-containing formulations
|
US5439686A
(en)
*
|
1993-02-22 |
1995-08-08 |
Vivorx Pharmaceuticals, Inc. |
Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
|
US5665382A
(en)
*
|
1993-02-22 |
1997-09-09 |
Vivorx Pharmaceuticals, Inc. |
Methods for the preparation of pharmaceutically active agents for in vivo delivery
|
US5916596A
(en)
*
|
1993-02-22 |
1999-06-29 |
Vivorx Pharmaceuticals, Inc. |
Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
|
US6528067B1
(en)
|
1993-02-22 |
2003-03-04 |
American Bioscience, Inc. |
Total nutrient admixtures as stable multicomponent liquids or dry powders and methods for the preparation thereof
|
JP3746293B2
(ja)
*
|
1993-02-22 |
2006-02-15 |
アメリカン バイオサイエンス、インコーポレイテッド |
生物製剤のインビボ送達の方法とそのための組成物
|
US5919466A
(en)
*
|
1993-10-01 |
1999-07-06 |
Gerbu Biotechnik Gmbh |
Method for improving the yield of immunoantibodies in the vaccination of animals and humans
|
US5716526A
(en)
*
|
1994-01-14 |
1998-02-10 |
The Liposome Company, Inc. |
Method of separating materials from liposomes or lipid complexes
|
KR100508910B1
(ko)
|
1995-10-17 |
2006-04-20 |
알티피 파마 코포레이션 |
불용성약물방출
|
US7255877B2
(en)
*
|
1996-08-22 |
2007-08-14 |
Jagotec Ag |
Fenofibrate microparticles
|
US6465016B2
(en)
|
1996-08-22 |
2002-10-15 |
Research Triangle Pharmaceuticals |
Cyclosporiine particles
|
US6565885B1
(en)
*
|
1997-09-29 |
2003-05-20 |
Inhale Therapeutic Systems, Inc. |
Methods of spray drying pharmaceutical compositions
|
US20060165606A1
(en)
*
|
1997-09-29 |
2006-07-27 |
Nektar Therapeutics |
Pulmonary delivery particles comprising water insoluble or crystalline active agents
|
ATE554748T1
(de)
*
|
1997-11-14 |
2012-05-15 |
Pacira Pharmaceuticals Inc |
Herstellung von multivesikulären liposomen
|
WO1999027940A1
(en)
*
|
1997-12-01 |
1999-06-10 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Formulations for topical treatment of skin infections
|
IL137734A0
(en)
*
|
1998-02-11 |
2001-10-31 |
Res Triangle Pharm Ltd |
Method and composition for treatment of inflammatory conditions
|
US6979456B1
(en)
|
1998-04-01 |
2005-12-27 |
Jagotec Ag |
Anticancer compositions
|
EP1079808B1
(de)
*
|
1998-05-29 |
2004-02-11 |
Skyepharma Canada Inc. |
Gegen hitzeeinwirkung geschützte mikropartikel und verfahren zur terminalen dampfsterilisation derselben
|
DK1105096T3
(da)
*
|
1998-08-19 |
2004-03-08 |
Skyepharma Canada Inc |
Injicerbare vandige propofoldispersioner
|
AU767737B2
(en)
*
|
1998-11-20 |
2003-11-20 |
Skyepharma Canada Inc. |
Method of preparing stable suspensions of insoluble microparticles
|
NZ511792A
(en)
|
1998-11-20 |
2003-08-29 |
Skyepharma Canada Inc |
Dispersible phospholipid stabilized microparticles
|
AU2530700A
(en)
*
|
1999-02-11 |
2000-08-29 |
Kinetana Inc. |
Serum albumin-based parenteral formulations of polyene macrolides
|
EP1074248A1
(de)
*
|
1999-07-08 |
2001-02-07 |
Arnold Hilgers |
Verabreichungssystem für biologisches Material
|
AU7984200A
(en)
*
|
1999-09-21 |
2001-04-24 |
Skyepharma Canada Inc. |
Surface modified particulate compositions of biologically active substances
|
ES2469642T3
(es)
|
2000-04-20 |
2014-06-18 |
Jagotec Ag |
Procedimiento mejorado para partículas de fármaco insoluble en agua
|
US7871598B1
(en)
|
2000-05-10 |
2011-01-18 |
Novartis Ag |
Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
|
US8404217B2
(en)
*
|
2000-05-10 |
2013-03-26 |
Novartis Ag |
Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
|
TWI290473B
(en)
|
2000-05-10 |
2007-12-01 |
Alliance Pharma |
Phospholipid-based powders for drug delivery
|
AU8847101A
(en)
|
2000-08-31 |
2002-03-13 |
Rtp Pharma Inc |
Milled particles
|
US8586094B2
(en)
*
|
2000-09-20 |
2013-11-19 |
Jagotec Ag |
Coated tablets
|
CA2423336C
(en)
*
|
2000-09-20 |
2011-03-08 |
Rtp Pharma Inc. |
Stabilised fibrate microparticles
|
US20040033267A1
(en)
*
|
2002-03-20 |
2004-02-19 |
Elan Pharma International Ltd. |
Nanoparticulate compositions of angiogenesis inhibitors
|
CA2424619C
(en)
*
|
2000-10-04 |
2010-05-18 |
Kyowa Hakko Kogyo Co., Ltd. |
Method for coating fine particles with lipid membrane
|
KR100743404B1
(ko)
|
2000-12-21 |
2007-07-30 |
넥타르 테라퓨틱스 |
폴리엔 항균제의 폐 전달
|
US6884436B2
(en)
*
|
2000-12-22 |
2005-04-26 |
Baxter International Inc. |
Method for preparing submicron particle suspensions
|
US20030072807A1
(en)
*
|
2000-12-22 |
2003-04-17 |
Wong Joseph Chung-Tak |
Solid particulate antifungal compositions for pharmaceutical use
|
US20040022862A1
(en)
*
|
2000-12-22 |
2004-02-05 |
Kipp James E. |
Method for preparing small particles
|
US6869617B2
(en)
*
|
2000-12-22 |
2005-03-22 |
Baxter International Inc. |
Microprecipitation method for preparing submicron suspensions
|
US8067032B2
(en)
*
|
2000-12-22 |
2011-11-29 |
Baxter International Inc. |
Method for preparing submicron particles of antineoplastic agents
|
US6977085B2
(en)
*
|
2000-12-22 |
2005-12-20 |
Baxter International Inc. |
Method for preparing submicron suspensions with polymorph control
|
US20040256749A1
(en)
*
|
2000-12-22 |
2004-12-23 |
Mahesh Chaubal |
Process for production of essentially solvent-free small particles
|
US6951656B2
(en)
*
|
2000-12-22 |
2005-10-04 |
Baxter International Inc. |
Microprecipitation method for preparing submicron suspensions
|
US20030096013A1
(en)
*
|
2000-12-22 |
2003-05-22 |
Jane Werling |
Preparation of submicron sized particles with polymorph control
|
US7193084B2
(en)
*
|
2000-12-22 |
2007-03-20 |
Baxter International Inc. |
Polymorphic form of itraconazole
|
US9700866B2
(en)
*
|
2000-12-22 |
2017-07-11 |
Baxter International Inc. |
Surfactant systems for delivery of organic compounds
|
US20050048126A1
(en)
*
|
2000-12-22 |
2005-03-03 |
Barrett Rabinow |
Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
|
ATE357216T1
(de)
*
|
2001-02-22 |
2007-04-15 |
Jagotec Ag |
Fibrat-statin kombinationen mit verminderten von der nahrungsaufnahme abhängigen auswirkungen
|
IN188924B
(de)
*
|
2001-03-01 |
2002-11-23 |
Bharat Serums & Vaccines Ltd |
|
EP1416917B1
(de)
|
2001-08-06 |
2007-06-27 |
AstraZeneca AB |
Wässrige dispersion stabiler nanopartikel eines wasserunlöslichen wirkstoffs und ein hilfsstoff wie mittelkettige triglyceride (mct)
|
US20030054042A1
(en)
*
|
2001-09-14 |
2003-03-20 |
Elaine Liversidge |
Stabilization of chemical compounds using nanoparticulate formulations
|
MXPA04002446A
(es)
*
|
2001-09-26 |
2004-07-23 |
Baxter Int |
Preparacion de nanoparticulas de tamano de submicras mediante dispersion y remocion de la fase liquida o solvente.
|
US20060003012A9
(en)
*
|
2001-09-26 |
2006-01-05 |
Sean Brynjelsen |
Preparation of submicron solid particle suspensions by sonication of multiphase systems
|
US20070281003A1
(en)
|
2001-10-12 |
2007-12-06 |
Fuisz Richard C |
Polymer-Based Films and Drug Delivery Systems Made Therefrom
|
US20190328679A1
(en)
|
2001-10-12 |
2019-10-31 |
Aquestive Therapeutics, Inc. |
Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
|
US11207805B2
(en)
|
2001-10-12 |
2021-12-28 |
Aquestive Therapeutics, Inc. |
Process for manufacturing a resulting pharmaceutical film
|
US8663687B2
(en)
*
|
2001-10-12 |
2014-03-04 |
Monosol Rx, Llc |
Film compositions for delivery of actives
|
US20110033542A1
(en)
|
2009-08-07 |
2011-02-10 |
Monosol Rx, Llc |
Sublingual and buccal film compositions
|
US7357891B2
(en)
|
2001-10-12 |
2008-04-15 |
Monosol Rx, Llc |
Process for making an ingestible film
|
US8900497B2
(en)
|
2001-10-12 |
2014-12-02 |
Monosol Rx, Llc |
Process for making a film having a substantially uniform distribution of components
|
US8765167B2
(en)
|
2001-10-12 |
2014-07-01 |
Monosol Rx, Llc |
Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
|
US10285910B2
(en)
|
2001-10-12 |
2019-05-14 |
Aquestive Therapeutics, Inc. |
Sublingual and buccal film compositions
|
US8603514B2
(en)
|
2002-04-11 |
2013-12-10 |
Monosol Rx, Llc |
Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
|
US8900498B2
(en)
|
2001-10-12 |
2014-12-02 |
Monosol Rx, Llc |
Process for manufacturing a resulting multi-layer pharmaceutical film
|
US7112340B2
(en)
*
|
2001-10-19 |
2006-09-26 |
Baxter International Inc. |
Compositions of and method for preparing stable particles in a frozen aqueous matrix
|
EP1306127B2
(de)
*
|
2001-10-26 |
2011-09-07 |
OctoPlus PolyActive Sciences B.V. |
Verfahren zur Herstellung von gereinigten Partikeln
|
EP2255821A1
(de)
|
2002-02-28 |
2010-12-01 |
Heitland & Petre International GmbH |
Mikro-/Nanopartikel aus lipidhaltigen marinen Organismen für Pharmazie und Kosmetik
|
JP4679822B2
(ja)
|
2002-03-13 |
2011-05-11 |
ノバルティス アーゲー |
医薬微粒子
|
US20080220075A1
(en)
*
|
2002-03-20 |
2008-09-11 |
Elan Pharma International Ltd. |
Nanoparticulate compositions of angiogenesis inhibitors
|
GB0230088D0
(en)
*
|
2002-12-24 |
2003-01-29 |
Astrazeneca Ab |
Therapeutic agents
|
GB0302672D0
(en)
*
|
2003-02-06 |
2003-03-12 |
Astrazeneca Ab |
Pharmaceutical formulations
|
GB0302671D0
(en)
*
|
2003-02-06 |
2003-03-12 |
Astrazeneca Ab |
Pharmaceutical formulations
|
GB0302673D0
(en)
*
|
2003-02-06 |
2003-03-12 |
Astrazeneca Ab |
Pharmaceutical formulations
|
EP1631669A2
(de)
|
2003-04-09 |
2006-03-08 |
Biodelivery Sciences International, Inc. |
Gegen proteinexpression gerichtete cochleat-zusammensetzungen
|
WO2004091578A2
(en)
|
2003-04-09 |
2004-10-28 |
Biodelivery Sciences International, Inc. |
Novel encochleation methods, cochleates and methods of use
|
KR20060012628A
(ko)
*
|
2003-05-19 |
2006-02-08 |
백스터 인터내셔널 인코포레이티드 |
하나 이상의 표면 변형제로 피복시킨 항경련제 또는면역억제제를 포함하는 고형 입자
|
GB0314057D0
(en)
*
|
2003-06-18 |
2003-07-23 |
Astrazeneca Ab |
Therapeutic agents
|
US20060135523A1
(en)
*
|
2003-06-18 |
2006-06-22 |
Astrazeneca Ab |
2-substituted 5,6-diaryl-pyrazine derivatives as cb1 modulator
|
GB0314261D0
(en)
*
|
2003-06-19 |
2003-07-23 |
Astrazeneca Ab |
Therapeutic agents
|
BRPI0414970A2
(pt)
*
|
2003-06-24 |
2012-12-11 |
Baxter Int |
método para transporte de drogas ao cérebro
|
US8986736B2
(en)
*
|
2003-06-24 |
2015-03-24 |
Baxter International Inc. |
Method for delivering particulate drugs to tissues
|
RU2392004C2
(ru)
|
2003-09-22 |
2010-06-20 |
Бакстер Интернэшнл Инк. |
Стерилизация под высоким давлением для заключительной стерилизации фармацевтических препаратов и медицинских изделий
|
RU2006130958A
(ru)
*
|
2004-01-29 |
2008-03-10 |
Бакстер Интернэшнл Инк. (Us) |
Наносуспензии антиретровирусных агентов для улучшенной доставки в центральную нервную систему
|
WO2005077337A2
(en)
*
|
2004-02-05 |
2005-08-25 |
Baxter International Inc. |
Dispersions prepared by use of self-stabilizing agents
|
EP1728550A4
(de)
*
|
2004-03-23 |
2007-09-05 |
Kyowa Hakko Kogyo Kk |
Verfahren zur herstellung von beschichteten feinen teilchen
|
EP1763576A2
(de)
*
|
2004-06-15 |
2007-03-21 |
Baxter International Inc. |
Ex-vivo anwendung von festen micropartikeln mit therapeutischen mitteln
|
CA2596058A1
(en)
*
|
2005-01-28 |
2006-08-03 |
Kyowa Hakko Kogyo Co., Ltd. |
Method of producing coated fine particles
|
KR20080027340A
(ko)
*
|
2005-06-14 |
2008-03-26 |
백스터 인터내셔널 인코포레이티드 |
약물-약물 상호작용을 최소화하기 위한 제약학적 제형
|
US20060280787A1
(en)
*
|
2005-06-14 |
2006-12-14 |
Baxter International Inc. |
Pharmaceutical formulation of the tubulin inhibitor indibulin for oral administration with improved pharmacokinetic properties, and process for the manufacture thereof
|
EP1915131A4
(de)
*
|
2005-08-12 |
2012-07-25 |
Astrazeneca Ab |
Verfahren
|
EP1954245A2
(de)
*
|
2005-11-15 |
2008-08-13 |
Baxter International Inc. |
Zusammensetzungen aus lipoxygenase-hemmern
|
WO2007092088A1
(en)
*
|
2005-12-28 |
2007-08-16 |
Nektar Therapeutics |
Compositions comprising amphotericin b
|
JP5089887B2
(ja)
*
|
2006-01-23 |
2012-12-05 |
日本精化株式会社 |
生理活性物質含有複合体
|
WO2008013785A2
(en)
|
2006-07-24 |
2008-01-31 |
Singh-Broemer And Company, Inc. |
Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
|
WO2008080047A2
(en)
*
|
2006-12-23 |
2008-07-03 |
Baxter International Inc. |
Magnetic separation of fine particles from compositions
|
JP2010517759A
(ja)
*
|
2007-02-09 |
2010-05-27 |
アストラゼネカ・アクチエボラーグ |
水性媒体中における固体非晶質サブミクロン粒子の安定な分散体を製造する方法
|
TW200848039A
(en)
*
|
2007-02-09 |
2008-12-16 |
Astrazeneca Ab |
Pharmaceutical compositions
|
CA2723470C
(en)
*
|
2007-05-07 |
2013-12-03 |
Hale Biopharma Ventures, Llc |
Nasal administration of benzodiazepines
|
US8530463B2
(en)
*
|
2007-05-07 |
2013-09-10 |
Hale Biopharma Ventures Llc |
Multimodal particulate formulations
|
US20080293814A1
(en)
*
|
2007-05-22 |
2008-11-27 |
Deepak Tiwari |
Concentrate esmolol
|
US8426467B2
(en)
*
|
2007-05-22 |
2013-04-23 |
Baxter International Inc. |
Colored esmolol concentrate
|
US8722736B2
(en)
*
|
2007-05-22 |
2014-05-13 |
Baxter International Inc. |
Multi-dose concentrate esmolol with benzyl alcohol
|
ES2447465T3
(es)
|
2008-03-05 |
2014-03-12 |
Baxter International Inc. |
Partículas de superficie modificada y métodos para la administración dirigida de fármacos
|
EP2271347B1
(de)
*
|
2008-03-28 |
2016-05-11 |
Hale Biopharma Ventures, Llc |
Verabreichung von benzodiazepin-zusammensetzungen
|
DE102008035442A1
(de)
|
2008-07-26 |
2010-01-28 |
Ernst-Moritz-Arndt-Universität Greifswald |
Zubereitungen aus Artemisia Annua, ihre Umwandlung in Mikro- und Nanopartikel und ihre Verwendung
|
US10952965B2
(en)
*
|
2009-05-15 |
2021-03-23 |
Baxter International Inc. |
Compositions and methods for drug delivery
|
TWI540319B
(zh)
|
2010-03-29 |
2016-07-01 |
中央研究院 |
以細胞質譜分析定量細胞所攝入之奈米/微米粒子
|
US9149959B2
(en)
|
2010-10-22 |
2015-10-06 |
Monosol Rx, Llc |
Manufacturing of small film strips
|
CN107737100A
(zh)
|
2011-06-14 |
2018-02-27 |
哈尔生物药投资有限责任公司 |
苯二氮卓组合物的投与
|
WO2013178749A1
(fr)
|
2012-06-01 |
2013-12-05 |
Galderma Research & Development |
Nanocapsules lipidiques comprenant un rétinoide, nanodispersion et composition les contenant, leur procédé de préparation et leur utilisation en dermatologie
|
JP2016539150A
(ja)
*
|
2013-12-04 |
2016-12-15 |
ガルデルマ・リサーチ・アンド・デヴェロップメント |
好ましくはレチノイドを含む脂質マイクロカプセル、及びそれを含有する組成物、それらの製造のための方法、並びに皮膚科学におけるそれらの使用
|
US11197831B2
(en)
*
|
2015-05-29 |
2021-12-14 |
Galderma Research And Development |
Compositions comprising at least one dispersed active principle and lipid microcapsules
|
US11273131B2
(en)
|
2016-05-05 |
2022-03-15 |
Aquestive Therapeutics, Inc. |
Pharmaceutical compositions with enhanced permeation
|
KR20190005199A
(ko)
|
2016-05-05 |
2019-01-15 |
어퀘스티브 테라퓨틱스, 아이엔씨. |
강화된 전달 에프네프린 조성물
|
RU2657767C1
(ru)
*
|
2017-08-07 |
2018-06-15 |
Александр Александрович Кролевец |
Способ получения нанокапсул стрептоцида в каппа-каррагинане
|
US11357727B1
(en)
|
2021-01-22 |
2022-06-14 |
Pacira Pharmaceuticals, Inc. |
Manufacturing of bupivacaine multivesicular liposomes
|
US11033495B1
(en)
|
2021-01-22 |
2021-06-15 |
Pacira Pharmaceuticals, Inc. |
Manufacturing of bupivacaine multivesicular liposomes
|
US11278494B1
(en)
|
2021-01-22 |
2022-03-22 |
Pacira Pharmaceuticals, Inc. |
Manufacturing of bupivacaine multivesicular liposomes
|