ATE160588T1 - Aus bakteriellen proteinen bestehender extrakt, verfahren zur dessen herstellung und diesen extrakt enthaltende pharmazeutische zusammensetzung - Google Patents

Aus bakteriellen proteinen bestehender extrakt, verfahren zur dessen herstellung und diesen extrakt enthaltende pharmazeutische zusammensetzung

Info

Publication number
ATE160588T1
ATE160588T1 AT93902023T AT93902023T ATE160588T1 AT E160588 T1 ATE160588 T1 AT E160588T1 AT 93902023 T AT93902023 T AT 93902023T AT 93902023 T AT93902023 T AT 93902023T AT E160588 T1 ATE160588 T1 AT E160588T1
Authority
AT
Austria
Prior art keywords
extract
pct
range
pharmaceutical composition
protein extract
Prior art date
Application number
AT93902023T
Other languages
English (en)
Inventor
Jacques Bauer
Pierre Hirt
Adrian Schulthess
Original Assignee
Om Lab Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Om Lab Sa filed Critical Om Lab Sa
Application granted granted Critical
Publication of ATE160588T1 publication Critical patent/ATE160588T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/851—Haemophilus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/852—Klebsiella
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/871—Neisseria
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/885—Streptococcus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
AT93902023T 1992-02-14 1993-02-03 Aus bakteriellen proteinen bestehender extrakt, verfahren zur dessen herstellung und diesen extrakt enthaltende pharmazeutische zusammensetzung ATE160588T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH450/92A CH685498A5 (fr) 1992-02-14 1992-02-14 Extrait de macromolécules bactériennes, procédé pour sa préparation et composition pharmaceutique contenant cet extrait.

Publications (1)

Publication Number Publication Date
ATE160588T1 true ATE160588T1 (de) 1997-12-15

Family

ID=4187312

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93902023T ATE160588T1 (de) 1992-02-14 1993-02-03 Aus bakteriellen proteinen bestehender extrakt, verfahren zur dessen herstellung und diesen extrakt enthaltende pharmazeutische zusammensetzung

Country Status (17)

Country Link
US (1) US5424287A (de)
EP (1) EP0580829B1 (de)
JP (1) JPH06507077A (de)
AT (1) ATE160588T1 (de)
BR (1) BR9304205A (de)
CA (1) CA2106854A1 (de)
CH (1) CH685498A5 (de)
CZ (1) CZ282924B6 (de)
DE (1) DE69315388T2 (de)
DK (1) DK0580829T3 (de)
ES (1) ES2111149T3 (de)
GR (1) GR3025882T3 (de)
HU (1) HU215262B (de)
PL (1) PL175058B1 (de)
RO (1) RO117621B1 (de)
SK (1) SK279877B6 (de)
WO (1) WO1993016190A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2703587B1 (fr) 1993-04-06 1995-06-16 Oreal Composition cosmetique coloree.
DE59505786D1 (de) 1994-02-07 1999-06-02 Qiagen Gmbh Verfahren zur abreicherung oder entfernung von endotoxinen
DE19710255A1 (de) * 1997-03-13 1998-09-17 Henkel Ecolab Gmbh & Co Ohg Verwendung einer Lösung zur Desaktivierung von Endotoxinen
FR2842208B1 (fr) * 2002-07-10 2004-10-22 Lco Sante Extraits membranaires de klebsiella presentant des proprietes avantageuses, et procede de production de ces extraits
US7714111B2 (en) * 2006-09-08 2010-05-11 Wyeth Llc Arginine derivative wash in protein purification using affinity chromatography
PL2114421T3 (pl) * 2007-03-05 2018-07-31 Om Pharma Ekstrakt bakteryjny do stosowania względem zaburzeń oddechowych i sposób jego wytwarzania
BRPI0808351A2 (pt) * 2007-03-05 2014-07-29 Om Pharma Extrato bacteriano para doenças do trato digestivo ou urinário e proesso para sua preparação.
AU2013200193B2 (en) * 2007-03-05 2015-04-23 Om Pharma Bacterial extract for digestive or urinary tract disorders and process for its preparation
AU2013202504B2 (en) * 2007-03-05 2014-09-11 Om Pharma Bacterial extract for respiratory disorders and process for its preparation
US20100055082A1 (en) * 2008-09-04 2010-03-04 Jacques Alain Bauer Immunomodulatory extracts from lactobacillus bacteria and methods of manufacturing and use thereof
CN102617703A (zh) * 2012-04-14 2012-08-01 拜明(苏州)生物技术有限公司 一种无需裂解高效提取发酵细菌中外源表达蛋白的方法
JP2014200194A (ja) * 2013-04-04 2014-10-27 浜松ホトニクス株式会社 細胞から細胞小器官又はタンパク質を回収する方法
EP4234026A2 (de) 2019-03-14 2023-08-30 OM Pharma SA Verfahren zur herstellung von stabilen bakteriellen extrakten und ihre verwendung als arzneimittel

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2405298A1 (fr) * 1977-01-27 1979-05-04 Cassenne Lab Sa Nouvelles glycoproteines isolees d'escherichia coli, procede de preparation et application de medicaments
FR2396018A1 (fr) * 1977-07-01 1979-01-26 Cassenne Lab Sa Nouveaux glycopeptides acetyles hydrosolubles extraits de corps microbiens lyses d'escherichia coli, procede de preparation et application a titre de medicaments de ces produits
CH633188A5 (fr) * 1978-05-26 1982-11-30 Om Laboratoires Sa Medicament contre des maladies infectieuses des voies respiratoires.

Also Published As

Publication number Publication date
JPH06507077A (ja) 1994-08-11
HUT70268A (en) 1995-09-28
PL301012A1 (en) 1994-04-05
DE69315388T2 (de) 1998-05-14
ES2111149T3 (es) 1998-03-01
BR9304205A (pt) 1994-08-02
RO117621B1 (ro) 2002-05-30
HU9302893D0 (en) 1994-01-28
SK279877B6 (sk) 1999-05-07
CA2106854A1 (en) 1993-08-15
US5424287A (en) 1995-06-13
CZ206493A3 (en) 1994-04-13
CZ282924B6 (cs) 1997-11-12
DE69315388D1 (de) 1998-01-08
PL175058B1 (pl) 1998-10-30
DK0580829T3 (da) 1998-08-10
EP0580829A1 (de) 1994-02-02
HU215262B (hu) 1998-11-30
GR3025882T3 (en) 1998-04-30
WO1993016190A1 (fr) 1993-08-19
CH685498A5 (fr) 1995-07-31
EP0580829B1 (de) 1997-11-26
SK111193A3 (en) 1994-03-09

Similar Documents

Publication Publication Date Title
ATE160588T1 (de) Aus bakteriellen proteinen bestehender extrakt, verfahren zur dessen herstellung und diesen extrakt enthaltende pharmazeutische zusammensetzung
CA2102208A1 (en) Binding domains in notch and delta proteins
ATE56729T1 (de) Protein mit zellwachstumsstimulierender wirkung, dessen zusammensetzung und verfahren zu seiner herstellung.
DE69631996D1 (de) Verfahren zur Herstellung von acylierten Proteinpuder
RU94046424A (ru) Способ разделения форм днказы, днказа человека, фармацевтическая композиция, способ хранения днказы, способ лечения
ATE89740T1 (de) Verfahren zur herstellung und zusammensetzungen von kollagen-derivaten.
AU6819294A (en) Oral drug delivery compositions and methods
FR2442054A1 (fr) Proteines purifiees, notamment interferon, procede de preparation et compositions pharmaceutiques les contenant
DE69937036D1 (de) Verfahren zur Herstellung von L-Aminosäuren
ATA253881A (de) Verfahren zur herstellung von neuen n-(vinblastin-23-oyl)-aminosaeurederivaten und von deren saeureadditionssalzen
DE3855113T2 (de) Verwendung von Buspiron zur Herstellung eines pharmazeutischen Präparats zur Behandlung der Alkoholsucht
JPH05504566A (ja) 生物学的活性を有するペプチドを使用した創傷処置方法
ATE95522T1 (de) Verfahren zur herstellung von des-b30-insulinen und des-b30-insulinderivaten.
DE69619860D1 (de) Verfahren zur herstellung aktiver substanzen aus perlmutt, resultierende produkte, geeignet für medizinische anwendungen
ATE125706T1 (de) Diphosphonate enthaltende pharmazeutische zusammensetzungen zur behandlung von arthrosis.
EP0173664A3 (de) Biologisch aktive Benzimidazolderivate und Verfahren zu ihrer Herstellung
DE3884680D1 (de) Äusseres Membranprotein F von Pseudomonas aeruginosa.
WO1995029999A3 (en) A process for separating milk clotting enzymes, and stable rennet compositions
EP0257312A3 (de) Vom Knorpel abstammende Leukozytenelastase hemmende Substanz
DE2448530C3 (de) Verfahren zum Herstellen von Derivaten des Diphtherietoxins und diese enthaltende Mittel
ATE233321T1 (de) Verbesserungen in der herstellung von proteinen in wirtszellen
ATE25708T1 (de) Biologisch aktive konjugate, ihre herstellung und ihre anwendung.
Farbiszewski et al. The digestion of basic proteins by extract of Guerin tumor lysosomes
JPS5625114A (en) Preparation of human gamma globulin
DE59704883D1 (de) Komplex aus antigen und zellbestandteil, verfahren zur dessen herstellung und therapeutische verwendungen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee