ATE72815T1 - Verfahren zur umwandlung von 6-(substituiertes methylen)-2-penem-e-isomer zum z-isomer. - Google Patents
Verfahren zur umwandlung von 6-(substituiertes methylen)-2-penem-e-isomer zum z-isomer.Info
- Publication number
- ATE72815T1 ATE72815T1 AT88304295T AT88304295T ATE72815T1 AT E72815 T1 ATE72815 T1 AT E72815T1 AT 88304295 T AT88304295 T AT 88304295T AT 88304295 T AT88304295 T AT 88304295T AT E72815 T1 ATE72815 T1 AT E72815T1
- Authority
- AT
- Austria
- Prior art keywords
- isomer
- penem
- substituted methylene
- conversion
- antibacterial
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Reverberation, Karaoke And Other Acoustics (AREA)
- Mechanical Coupling Of Light Guides (AREA)
- Cephalosporin Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
- Glass Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878711391A GB8711391D0 (en) | 1987-05-14 | 1987-05-14 | Process |
| EP88304295A EP0291304B1 (de) | 1987-05-14 | 1988-05-12 | Verfahren zur Umwandlung von 6-(substituiertes Methylen)-2-penem-E-Isomer zum Z-Isomer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE72815T1 true ATE72815T1 (de) | 1992-03-15 |
Family
ID=10617325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88304295T ATE72815T1 (de) | 1987-05-14 | 1988-05-12 | Verfahren zur umwandlung von 6-(substituiertes methylen)-2-penem-e-isomer zum z-isomer. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4897476A (de) |
| EP (1) | EP0291304B1 (de) |
| JP (1) | JPH0816112B2 (de) |
| KR (1) | KR880013944A (de) |
| AT (1) | ATE72815T1 (de) |
| AU (1) | AU614517B2 (de) |
| CA (1) | CA1300603C (de) |
| DE (1) | DE3868534D1 (de) |
| DK (1) | DK260288A (de) |
| ES (1) | ES2030167T3 (de) |
| GB (1) | GB8711391D0 (de) |
| GR (1) | GR3003907T3 (de) |
| NZ (1) | NZ224592A (de) |
| PT (1) | PT87465B (de) |
| ZA (1) | ZA883346B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8729613D0 (en) * | 1987-12-18 | 1988-02-03 | Beecham Group Plc | Novel compounds |
| US6255091B1 (en) * | 1995-04-28 | 2001-07-03 | Axys Pharmaceuticals, Inc. | Potentiating metal mediated serine protease inhibitors with cobalt or zinc ions |
| US5693515A (en) * | 1995-04-28 | 1997-12-02 | Arris Pharmaceutical Corporation | Metal complexed serine protease inhibitors |
| CN114681435A (zh) | 2020-12-31 | 2022-07-01 | 上海汇伦生物科技有限公司 | 吸入用药物组合物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3169567D1 (en) * | 1980-10-25 | 1985-05-02 | Beecham Group Plc | The preparation of beta-lactam antibiotics |
| EP0120613A1 (de) * | 1983-03-02 | 1984-10-03 | Beecham Group Plc | Penem-Derivate und Vorstufenverbindungen |
| FI82471C (fi) * | 1984-01-26 | 1991-03-11 | Beecham Group Plc | Foerfarande foer framstaellning av farmakologiskt aktiva 6-metylenpenemderivater. |
| GB8402086D0 (en) * | 1984-01-26 | 1984-02-29 | Beecham Group Plc | Compounds |
| GB8518422D0 (en) * | 1985-07-22 | 1985-08-29 | Beecham Group Plc | Compounds |
| EP0232966B1 (de) * | 1986-01-17 | 1997-10-08 | Beecham Group Plc | Verfahren zur Herstellung von Penem Derivaten und Zwischenprodukte zu dieser Herstellung |
| AT396788B (de) * | 1990-02-07 | 1993-11-25 | Hofer Kerzen Gmbh | Kerzenleuchte |
-
1987
- 1987-05-14 GB GB878711391A patent/GB8711391D0/en active Pending
-
1988
- 1988-05-11 DK DK260288A patent/DK260288A/da not_active Application Discontinuation
- 1988-05-11 ZA ZA883346A patent/ZA883346B/xx unknown
- 1988-05-12 CA CA000566571A patent/CA1300603C/en not_active Expired - Fee Related
- 1988-05-12 DE DE8888304295T patent/DE3868534D1/de not_active Expired - Lifetime
- 1988-05-12 JP JP63115927A patent/JPH0816112B2/ja not_active Expired - Lifetime
- 1988-05-12 AU AU16092/88A patent/AU614517B2/en not_active Ceased
- 1988-05-12 ES ES198888304295T patent/ES2030167T3/es not_active Expired - Lifetime
- 1988-05-12 PT PT87465A patent/PT87465B/pt not_active IP Right Cessation
- 1988-05-12 NZ NZ224592A patent/NZ224592A/xx unknown
- 1988-05-12 AT AT88304295T patent/ATE72815T1/de not_active IP Right Cessation
- 1988-05-12 US US07/193,746 patent/US4897476A/en not_active Expired - Lifetime
- 1988-05-12 EP EP88304295A patent/EP0291304B1/de not_active Expired - Lifetime
- 1988-05-13 KR KR1019880005594A patent/KR880013944A/ko not_active Application Discontinuation
-
1992
- 1992-02-27 GR GR920400320T patent/GR3003907T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ224592A (en) | 1990-07-26 |
| JPH0816112B2 (ja) | 1996-02-21 |
| PT87465B (pt) | 1992-09-30 |
| KR880013944A (ko) | 1988-12-22 |
| DK260288A (da) | 1988-11-15 |
| ZA883346B (en) | 1989-11-29 |
| US4897476A (en) | 1990-01-30 |
| AU614517B2 (en) | 1991-09-05 |
| GB8711391D0 (en) | 1987-06-17 |
| JPS63303985A (ja) | 1988-12-12 |
| ES2030167T3 (es) | 1992-10-16 |
| AU1609288A (en) | 1988-11-17 |
| EP0291304A1 (de) | 1988-11-17 |
| CA1300603C (en) | 1992-05-12 |
| DK260288D0 (da) | 1988-05-11 |
| PT87465A (pt) | 1989-05-31 |
| EP0291304B1 (de) | 1992-02-26 |
| GR3003907T3 (de) | 1993-03-16 |
| DE3868534D1 (de) | 1992-04-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |