ZA883346B - Process for the conversion of the e-isomer of 6-(substituted methylene)-2-penems into the z-isomer - Google Patents

Process for the conversion of the e-isomer of 6-(substituted methylene)-2-penems into the z-isomer

Info

Publication number
ZA883346B
ZA883346B ZA883346A ZA883346A ZA883346B ZA 883346 B ZA883346 B ZA 883346B ZA 883346 A ZA883346 A ZA 883346A ZA 883346 A ZA883346 A ZA 883346A ZA 883346 B ZA883346 B ZA 883346B
Authority
ZA
South Africa
Prior art keywords
isomer
substituted methylene
penems
conversion
antibacterial
Prior art date
Application number
ZA883346A
Other languages
English (en)
Inventor
Nigel John Perryman Broom
John Perryman Broom Nigel
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of ZA883346B publication Critical patent/ZA883346B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Mechanical Coupling Of Light Guides (AREA)
  • Reverberation, Karaoke And Other Acoustics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
ZA883346A 1987-05-14 1988-05-11 Process for the conversion of the e-isomer of 6-(substituted methylene)-2-penems into the z-isomer ZA883346B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878711391A GB8711391D0 (en) 1987-05-14 1987-05-14 Process

Publications (1)

Publication Number Publication Date
ZA883346B true ZA883346B (en) 1989-11-29

Family

ID=10617325

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA883346A ZA883346B (en) 1987-05-14 1988-05-11 Process for the conversion of the e-isomer of 6-(substituted methylene)-2-penems into the z-isomer

Country Status (15)

Country Link
US (1) US4897476A (xx)
EP (1) EP0291304B1 (xx)
JP (1) JPH0816112B2 (xx)
KR (1) KR880013944A (xx)
AT (1) ATE72815T1 (xx)
AU (1) AU614517B2 (xx)
CA (1) CA1300603C (xx)
DE (1) DE3868534D1 (xx)
DK (1) DK260288A (xx)
ES (1) ES2030167T3 (xx)
GB (1) GB8711391D0 (xx)
GR (1) GR3003907T3 (xx)
NZ (1) NZ224592A (xx)
PT (1) PT87465B (xx)
ZA (1) ZA883346B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8729613D0 (en) * 1987-12-18 1988-02-03 Beecham Group Plc Novel compounds
US5693515A (en) * 1995-04-28 1997-12-02 Arris Pharmaceutical Corporation Metal complexed serine protease inhibitors
US6255091B1 (en) 1995-04-28 2001-07-03 Axys Pharmaceuticals, Inc. Potentiating metal mediated serine protease inhibitors with cobalt or zinc ions
CN114681435A (zh) 2020-12-31 2022-07-01 上海汇伦生物科技有限公司 吸入用药物组合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3169567D1 (en) * 1980-10-25 1985-05-02 Beecham Group Plc The preparation of beta-lactam antibiotics
EP0120613A1 (en) * 1983-03-02 1984-10-03 Beecham Group Plc Penem derivatives and precursors
FI82471C (fi) * 1984-01-26 1991-03-11 Beecham Group Plc Foerfarande foer framstaellning av farmakologiskt aktiva 6-metylenpenemderivater.
GB8402086D0 (en) * 1984-01-26 1984-02-29 Beecham Group Plc Compounds
GB8518422D0 (en) * 1985-07-22 1985-08-29 Beecham Group Plc Compounds
DE3752124T2 (de) * 1986-01-17 1998-03-26 Beecham Group Plc Verfahren zur Herstellung von Penem Derivaten und Zwischenprodukte zu dieser Herstellung
AT396788B (de) * 1990-02-07 1993-11-25 Hofer Kerzen Gmbh Kerzenleuchte

Also Published As

Publication number Publication date
ATE72815T1 (de) 1992-03-15
PT87465B (pt) 1992-09-30
KR880013944A (ko) 1988-12-22
PT87465A (pt) 1989-05-31
EP0291304A1 (en) 1988-11-17
JPH0816112B2 (ja) 1996-02-21
AU1609288A (en) 1988-11-17
NZ224592A (en) 1990-07-26
AU614517B2 (en) 1991-09-05
GR3003907T3 (xx) 1993-03-16
DE3868534D1 (de) 1992-04-02
GB8711391D0 (en) 1987-06-17
JPS63303985A (ja) 1988-12-12
DK260288D0 (da) 1988-05-11
US4897476A (en) 1990-01-30
ES2030167T3 (es) 1992-10-16
CA1300603C (en) 1992-05-12
DK260288A (da) 1988-11-15
EP0291304B1 (en) 1992-02-26

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