PT87465A - Process for the preparation of (z)-6-(substituted methylene)-penems - Google Patents

Process for the preparation of (z)-6-(substituted methylene)-penems

Info

Publication number
PT87465A
PT87465A PT87465A PT8746588A PT87465A PT 87465 A PT87465 A PT 87465A PT 87465 A PT87465 A PT 87465A PT 8746588 A PT8746588 A PT 8746588A PT 87465 A PT87465 A PT 87465A
Authority
PT
Portugal
Prior art keywords
isomer
preparation
substituted methylene
penems
antibacterial
Prior art date
Application number
PT87465A
Other languages
English (en)
Other versions
PT87465B (pt
Inventor
Nigel John Perryman Broom
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of PT87465A publication Critical patent/PT87465A/pt
Publication of PT87465B publication Critical patent/PT87465B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Reverberation, Karaoke And Other Acoustics (AREA)
  • Mechanical Coupling Of Light Guides (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Glass Compositions (AREA)
PT87465A 1987-05-14 1988-05-12 Processo para a preparacao de (z)-6-(metileno substituido)-penems PT87465B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878711391A GB8711391D0 (en) 1987-05-14 1987-05-14 Process

Publications (2)

Publication Number Publication Date
PT87465A true PT87465A (pt) 1989-05-31
PT87465B PT87465B (pt) 1992-09-30

Family

ID=10617325

Family Applications (1)

Application Number Title Priority Date Filing Date
PT87465A PT87465B (pt) 1987-05-14 1988-05-12 Processo para a preparacao de (z)-6-(metileno substituido)-penems

Country Status (15)

Country Link
US (1) US4897476A (pt)
EP (1) EP0291304B1 (pt)
JP (1) JPH0816112B2 (pt)
KR (1) KR880013944A (pt)
AT (1) ATE72815T1 (pt)
AU (1) AU614517B2 (pt)
CA (1) CA1300603C (pt)
DE (1) DE3868534D1 (pt)
DK (1) DK260288A (pt)
ES (1) ES2030167T3 (pt)
GB (1) GB8711391D0 (pt)
GR (1) GR3003907T3 (pt)
NZ (1) NZ224592A (pt)
PT (1) PT87465B (pt)
ZA (1) ZA883346B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8729613D0 (en) * 1987-12-18 1988-02-03 Beecham Group Plc Novel compounds
US5693515A (en) * 1995-04-28 1997-12-02 Arris Pharmaceutical Corporation Metal complexed serine protease inhibitors
US6255091B1 (en) 1995-04-28 2001-07-03 Axys Pharmaceuticals, Inc. Potentiating metal mediated serine protease inhibitors with cobalt or zinc ions
CN114681435A (zh) 2020-12-31 2022-07-01 上海汇伦生物科技有限公司 吸入用药物组合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0050927B1 (en) * 1980-10-25 1985-03-27 Beecham Group Plc The preparation of beta-lactam antibiotics
EP0120613A1 (en) * 1983-03-02 1984-10-03 Beecham Group Plc Penem derivatives and precursors
FI82471C (fi) * 1984-01-26 1991-03-11 Beecham Group Plc Foerfarande foer framstaellning av farmakologiskt aktiva 6-metylenpenemderivater.
GB8402086D0 (en) * 1984-01-26 1984-02-29 Beecham Group Plc Compounds
GB8518422D0 (en) * 1985-07-22 1985-08-29 Beecham Group Plc Compounds
EP0232966B1 (en) * 1986-01-17 1997-10-08 Beecham Group Plc Process for the preparation of penem compounds and intermediates for this preparation
AT396788B (de) * 1990-02-07 1993-11-25 Hofer Kerzen Gmbh Kerzenleuchte

Also Published As

Publication number Publication date
DK260288A (da) 1988-11-15
AU1609288A (en) 1988-11-17
US4897476A (en) 1990-01-30
EP0291304B1 (en) 1992-02-26
KR880013944A (ko) 1988-12-22
CA1300603C (en) 1992-05-12
JPS63303985A (ja) 1988-12-12
PT87465B (pt) 1992-09-30
ATE72815T1 (de) 1992-03-15
ZA883346B (en) 1989-11-29
AU614517B2 (en) 1991-09-05
DK260288D0 (da) 1988-05-11
EP0291304A1 (en) 1988-11-17
GR3003907T3 (pt) 1993-03-16
DE3868534D1 (de) 1992-04-02
JPH0816112B2 (ja) 1996-02-21
NZ224592A (en) 1990-07-26
ES2030167T3 (es) 1992-10-16
GB8711391D0 (en) 1987-06-17

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920310

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19930930