ATE550331T1 - Glycosidasehemmer und verfahren zu dessen herstellung - Google Patents
Glycosidasehemmer und verfahren zu dessen herstellungInfo
- Publication number
- ATE550331T1 ATE550331T1 AT01901078T AT01901078T ATE550331T1 AT E550331 T1 ATE550331 T1 AT E550331T1 AT 01901078 T AT01901078 T AT 01901078T AT 01901078 T AT01901078 T AT 01901078T AT E550331 T1 ATE550331 T1 AT E550331T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- production
- glycosidase inhibitors
- compounds
- episulfides
- Prior art date
Links
- 239000003316 glycosidase inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000001541 aziridines Chemical class 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 150000001942 cyclopropanes Chemical class 0.000 abstract 1
- 150000002118 epoxides Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 229930195734 saturated hydrocarbon Natural products 0.000 abstract 1
- 150000003553 thiiranes Chemical class 0.000 abstract 1
- 229930195735 unsaturated hydrocarbon Natural products 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/46—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D345/00—Heterocyclic compounds containing rings having selenium or tellurium atoms as the only ring hetero atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17483700P | 2000-01-07 | 2000-01-07 | |
| US09/627,434 US6455573B1 (en) | 2000-01-07 | 2000-07-28 | Glycosidase inhibitors and methods of synthesizing same |
| PCT/CA2001/000010 WO2001049674A2 (en) | 2000-01-07 | 2001-01-05 | Glycosidase inhibitors and preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE550331T1 true ATE550331T1 (de) | 2012-04-15 |
Family
ID=26870587
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01901078T ATE550331T1 (de) | 2000-01-07 | 2001-01-05 | Glycosidasehemmer und verfahren zu dessen herstellung |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6455573B1 (de) |
| EP (2) | EP2325179A1 (de) |
| JP (1) | JP5053494B2 (de) |
| CN (1) | CN100341870C (de) |
| AT (1) | ATE550331T1 (de) |
| AU (1) | AU783127B2 (de) |
| CA (1) | CA2396688C (de) |
| WO (1) | WO2001049674A2 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8389565B2 (en) * | 2000-01-07 | 2013-03-05 | Simon Fraser University | Glycosidase inhibitors and methods of synthesizing same |
| JP4516282B2 (ja) * | 2003-04-24 | 2010-08-04 | 森下仁丹株式会社 | 新規なα−グルコシダーゼ阻害活性を有する物質およびこれを含有する食品 |
| JP4486792B2 (ja) * | 2003-06-12 | 2010-06-23 | 学校法人近畿大学 | 環状オニウム化合物およびグルコシダーゼ阻害剤 |
| AU2004249343A1 (en) * | 2003-06-25 | 2004-12-29 | Simon Fraser University | Glycosidase inhibitors and methods of synthesizing same |
| JP2008514549A (ja) * | 2004-09-14 | 2008-05-08 | エリクシアー ファーマシューティカルズ， インコーポレイテッド | 制御された炭水化物消化のための併用療法 |
| PT103385B (pt) * | 2005-11-15 | 2011-06-27 | Jorge Ruas Da Silva | Ácido 2,3,4,5-tetrahidróxi-6-sulfooxi-hexanoico, seus sais farmaceuticamente aceitáveis e suas formas de equilíbrio, processo para a sua preparação, composições farmacêuticas contendo estes compostos e seu uso em medicina |
| CN104530068B (zh) * | 2007-05-22 | 2017-05-03 | 阿米库斯治疗学公司 | 用于制备异法戈明的化合物 |
| US20090011060A1 (en) * | 2007-07-06 | 2009-01-08 | Peter Koepke | Campsiandra angustifolia extract and methods of extracting and using such extract |
| US20090017140A1 (en) * | 2007-07-09 | 2009-01-15 | Peter Koepke | Maytenus abenfolia extract and methods of extracting and using such extract |
| US20090035395A1 (en) * | 2007-08-01 | 2009-02-05 | Peter Koepke | Spondias mombin l. extract and methods of extracting and using such extract |
| US7879369B2 (en) * | 2007-09-18 | 2011-02-01 | Selvamedica, Llc | Combretum laurifolium Mart. extract and methods of extracting and using such extract |
| CN102413840A (zh) * | 2009-04-22 | 2012-04-11 | 富士胶片株式会社 | 肠道细菌群落构成比例调节剂 |
| JP5934120B2 (ja) | 2011-01-31 | 2016-06-15 | 学校法人近畿大学 | 環状スルホニウム塩、その製造方法およびそれを用いたα−グルコシダーゼ阻害剤 |
| JP5635932B2 (ja) * | 2011-03-30 | 2014-12-03 | 富士フイルム株式会社 | プロセシンググルコシダーゼ阻害剤 |
| US20150050371A1 (en) | 2012-03-09 | 2015-02-19 | Biotropics Malaysia Berhad | Extract Formulations of Rhodamnia Cinerea And Uses Thereof |
| JP6268014B2 (ja) * | 2014-03-20 | 2018-01-24 | 富士フイルム株式会社 | サラシノールの製造に有用な化合物およびそれらの製造法、サラシノールの製造法、ジオール基の保護方法および脱保護方法、並びにジオール基の保護剤 |
| TWI759267B (zh) | 2015-07-02 | 2022-04-01 | 美商地平線罕見醫學製藥有限責任公司 | Ａｄｏ抗性半胱胺類似物及其用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0389723A1 (de) * | 1989-03-29 | 1990-10-03 | Merrell Dow Pharmaceuticals Inc. | Alpha-glukosidase-Inhibitoren |
| US6121489A (en) * | 1996-03-05 | 2000-09-19 | Trega Biosciences, Inc. | Selectively N-alkylated peptidomimetic combinatorial libraries and compounds therein |
| GB9620884D0 (en) * | 1996-10-07 | 1996-11-27 | Mcdermott Sa J Ray | Reel to reel transfer of pipe and large diameter tubing |
| JP3030008B2 (ja) | 1997-07-07 | 2000-04-10 | 株式会社 タカマシステム | α−グルコシダーゼの阻害作用を有する化合物 |
-
2000
- 2000-07-28 US US09/627,434 patent/US6455573B1/en not_active Expired - Lifetime
-
2001
- 2001-01-05 EP EP10185651A patent/EP2325179A1/de not_active Withdrawn
- 2001-01-05 WO PCT/CA2001/000010 patent/WO2001049674A2/en not_active Ceased
- 2001-01-05 JP JP2001550214A patent/JP5053494B2/ja not_active Expired - Fee Related
- 2001-01-05 CA CA2396688A patent/CA2396688C/en not_active Expired - Lifetime
- 2001-01-05 AU AU26591/01A patent/AU783127B2/en not_active Expired
- 2001-01-05 EP EP01901078A patent/EP1248779B1/de not_active Expired - Lifetime
- 2001-01-05 AT AT01901078T patent/ATE550331T1/de active
- 2001-01-05 CN CNB018050220A patent/CN100341870C/zh not_active Expired - Lifetime
-
2002
- 2002-08-22 US US10/226,657 patent/US20030191104A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2659101A (en) | 2001-07-16 |
| CN100341870C (zh) | 2007-10-10 |
| EP1248779B1 (de) | 2012-03-21 |
| US20030191104A1 (en) | 2003-10-09 |
| EP2325179A1 (de) | 2011-05-25 |
| WO2001049674A3 (en) | 2001-11-29 |
| EP1248779A2 (de) | 2002-10-16 |
| WO2001049674A2 (en) | 2001-07-12 |
| AU783127B2 (en) | 2005-09-29 |
| CA2396688C (en) | 2013-05-21 |
| CA2396688A1 (en) | 2001-07-12 |
| JP2003519220A (ja) | 2003-06-17 |
| CN1404476A (zh) | 2003-03-19 |
| US6455573B1 (en) | 2002-09-24 |
| JP5053494B2 (ja) | 2012-10-17 |
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