ATE543T1 - Diagnostisches mittel, verfahren zu dessen herstellung sowie dessen verwendung zum nachweis von leukozyten in koerperfluessigkeiten. - Google Patents

Diagnostisches mittel, verfahren zu dessen herstellung sowie dessen verwendung zum nachweis von leukozyten in koerperfluessigkeiten.

Info

Publication number
ATE543T1
ATE543T1 AT80100671T AT80100671T ATE543T1 AT E543 T1 ATE543 T1 AT E543T1 AT 80100671 T AT80100671 T AT 80100671T AT 80100671 T AT80100671 T AT 80100671T AT E543 T1 ATE543 T1 AT E543T1
Authority
AT
Austria
Prior art keywords
preparation
body fluid
diagnostic agent
detecting leukocytes
leukocytes
Prior art date
Application number
AT80100671T
Other languages
German (de)
English (en)
Inventor
Dieter Dr.Rer.Nat. Berger
Guenter Frey
Manfred Dr.Rer.Nat. Kuhr
Wolfgang Dr.Rer.Nat. Werner
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6062854&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE543(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Application granted granted Critical
Publication of ATE543T1 publication Critical patent/ATE543T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B11/00Diaryl- or thriarylmethane dyes
    • C09B11/04Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
    • C09B11/06Hydroxy derivatives of triarylmethanes in which at least one OH group is bound to an aryl nucleus and their ethers or esters
    • C09B11/08Phthaleins; Phenolphthaleins; Fluorescein
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B43/00Preparation of azo dyes from other azo compounds
    • C09B43/18Preparation of azo dyes from other azo compounds by acylation of hydroxyl group or of mercapto group
    • C09B43/20Preparation of azo dyes from other azo compounds by acylation of hydroxyl group or of mercapto group with monocarboxylic acids, carbamic acid esters or halides, mono- isocyanates or haloformic acid esters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/44Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2334/00O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
    • C12Q2334/40Triphenylmethane dye chromogens, e.g. fluorescein derivatives
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2334/00O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
    • C12Q2334/50Indoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
AT80100671T 1979-02-14 1980-02-11 Diagnostisches mittel, verfahren zu dessen herstellung sowie dessen verwendung zum nachweis von leukozyten in koerperfluessigkeiten. ATE543T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19792905531 DE2905531A1 (de) 1979-02-14 1979-02-14 Diagnostisches mittel zum nachweis von leukozyten in koerperfluessigkeiten
EP80100671A EP0014929B1 (de) 1979-02-14 1980-02-11 Diagnostisches Mittel, Verfahren zu dessen Herstellung sowie dessen Verwendung zum Nachweis von Leukozyten in Körperflüssigkeiten

Publications (1)

Publication Number Publication Date
ATE543T1 true ATE543T1 (de) 1982-01-15

Family

ID=6062854

Family Applications (1)

Application Number Title Priority Date Filing Date
AT80100671T ATE543T1 (de) 1979-02-14 1980-02-11 Diagnostisches mittel, verfahren zu dessen herstellung sowie dessen verwendung zum nachweis von leukozyten in koerperfluessigkeiten.

Country Status (22)

Country Link
US (1) US4299917A (da)
EP (1) EP0014929B1 (da)
JP (1) JPS581920B2 (da)
AR (1) AR223025A1 (da)
AT (1) ATE543T1 (da)
AU (1) AU519912B2 (da)
BR (1) BR8000886A (da)
CA (1) CA1148073A (da)
CS (1) CS216523B2 (da)
DD (1) DD149121A5 (da)
DE (2) DE2905531A1 (da)
DK (1) DK161340C (da)
ES (1) ES8102726A1 (da)
FI (1) FI69869C (da)
HK (1) HK15285A (da)
HU (1) HU182102B (da)
PL (1) PL125796B1 (da)
PT (1) PT70813A (da)
RU (1) RU1784097C (da)
SG (1) SG79484G (da)
YU (2) YU45527B (da)
ZA (1) ZA80765B (da)

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DE3005845A1 (de) * 1980-02-16 1981-09-03 Boehringer Mannheim Gmbh, 6800 Mannheim Aminosaeure- und peptidester von leuko-indoanilinen, verfahren zu deren herstellung sowie diese verbindungen enthaltende mittel zum nachweis proteolytischer enzyme
DE3017721A1 (de) * 1980-05-09 1981-11-26 Boehringer Mannheim Gmbh, 6800 Mannheim Mittel zum nachweis esterolytischer und/oder proteolytischer enzyme und dafuer geeignete substrate
DE3118381A1 (de) * 1981-05-09 1982-11-25 Boehringer Mannheim Gmbh, 6800 Mannheim Mehrschichtiges testmittel zum nachweis einer komponente einer fluessigen probe
DE3211254A1 (de) * 1982-03-26 1983-09-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zum nachweis des vorliegens einer allergie und zum spezifischen nachweis des fuer die allergie verantwortlichen allergens
US4499185A (en) * 1982-05-17 1985-02-12 Miles Laboratories, Inc. Test for esterase activity in a liquid sample
DE3309544A1 (de) * 1983-03-17 1984-09-20 Macherey-Nagel & Co Chemikalienhandel, 5160 Düren Teststreifen zum nachweis von leukozyten im harn
DE3413120A1 (de) * 1984-04-06 1985-10-24 Miles Laboratories, Inc., Elkhart, Ind. Analysenverfahren und mittel zum nachweis esterolytischer und/oder proteolytischer enzyme
US4645842A (en) * 1984-04-06 1987-02-24 Miles Laboratories, Inc. Pyrrole compounds for detecting the presence of hydrolytic analytes
US4657855A (en) * 1984-04-06 1987-04-14 Miles Laboratories, Inc. Composition and test device for determining the presence of leukocytes, esterase and protease in a test sample
DE3413119A1 (de) * 1984-04-06 1985-10-24 Miles Laboratories, Inc., Elkhart, Ind. Analysenverfahren und mittel zum nachweis esterolytischer und/oder proteolytischer enzyme
US4637979A (en) * 1984-04-06 1987-01-20 Miles Laboratories, Inc. Composition and test device for determining the presence of leukocytes containing a zwitterion coupling agent
DE3413118A1 (de) * 1984-04-06 1985-10-24 Miles Laboratories, Inc., Elkhart, Ind. Analysenverfahren und mittel zum nachweis esterolytischer und/oder proteolytischer enzyme
DD247808C2 (de) * 1984-04-09 1989-01-11 Dresden Arzneimittel Teststreifen zur aufnahme von blutzuckertagesprofilen und verfahren zu seiner herstellung
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DE19651886A1 (de) * 1996-12-13 1998-06-18 Merck Patent Gmbh Mittel und Verfahren zur Bestimmung von hydrolytischen Enzymen
US6348324B1 (en) 1999-01-21 2002-02-19 Hypoguard America Limited Composition and device for detecting leukocytes in urine
US6528652B1 (en) * 1999-01-21 2003-03-04 Chronimed Composition and device for detecting leukocytes in urine
US7781396B2 (en) * 2002-01-31 2010-08-24 Tel Aviv University Future Technology Development L.P. Peptides directed for diagnosis and treatment of amyloid-associated disease
US20040052928A1 (en) * 2002-09-06 2004-03-18 Ehud Gazit Peptides and methods using same for diagnosing and treating amyloid-associated diseases
US6709868B2 (en) * 2002-05-20 2004-03-23 Portascience Inc. Method and apparatus for measuring white blood cell count
JPWO2004035522A1 (ja) * 2002-08-30 2006-02-16 株式会社 ビーエフ研究所 プリオン蛋白蓄積性疾患の診断プローブおよび治療薬ならびにプリオン蛋白の染色剤
US7491699B2 (en) 2002-12-09 2009-02-17 Ramot At Tel Aviv University Ltd. Peptide nanostructures and methods of generating and using the same
US20040126897A1 (en) 2002-12-19 2004-07-01 3M Innovative Properties Company Colorimetric sensors constructed of diacetylene materials
US6963007B2 (en) 2002-12-19 2005-11-08 3M Innovative Properties Company Diacetylenic materials for sensing applications
EP1583713B1 (en) * 2003-01-07 2009-03-25 Ramot at Tel Aviv University Ltd. Peptide nanostructures encapsulating a foreign material and method of manufacturing same
CA2530927A1 (en) * 2003-06-30 2005-01-06 Tel Aviv University Future Technology Development L.P. Peptides antibodies directed thereagainst and methods using same for diagnosing and treating amyloid-associated diseases
JP4917889B2 (ja) * 2003-09-25 2012-04-18 テル アヴィヴ ユニヴァーシティ フューチャー テクノロジー ディヴェロップメント エル.ピー. アミロイド関連疾患を処置するための組成物及びその使用方法
WO2005031362A2 (en) * 2003-10-02 2005-04-07 Ramot At Tel Aviv University Ltd. Novel antibacterial agents and methods of identifying and utilizing same
US20090156471A1 (en) * 2004-07-15 2009-06-18 Ramot At Tel Aviv University Ltd. Use of anti-amyloid agents for treating and typing pathogen infections
EP1781310B1 (en) * 2004-08-02 2015-10-14 Ramot at Tel Aviv University Ltd. Articles of peptide nanostructures and method of forming the same
ATE539745T1 (de) * 2004-08-19 2012-01-15 Univ Tel Aviv Future Tech Dev Zusammensetzungen zur behandlung von amyloid- assoziierten erkrankungen
WO2006027780A2 (en) 2004-09-08 2006-03-16 Ramot At Tel Aviv University Ltd. Peptide nanostructures containing end-capping modified peptides and methods of generating and using the same
JP2008524603A (ja) * 2004-12-17 2008-07-10 スリーエム イノベイティブ プロパティズ カンパニー ジアセチレン物質で構成される比色分析センサー
GB2426334A (en) * 2005-05-20 2006-11-22 Orion Diagnostica Oy Application of a reagent to a matrix material
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US7879212B2 (en) * 2005-11-03 2011-02-01 Ramot At Tel-Aviv University Ltd. Peptide nanostructure-coated electrodes
JP2011504236A (ja) * 2007-11-20 2011-02-03 スリーエム イノベイティブ プロパティズ カンパニー ジアセチレンを含むポリマーセンサーを用いる細菌試料の分析方法
US9103796B2 (en) 2007-12-14 2015-08-11 Kimberly-Clark Worldwide, Inc. Multi-layered devices for analyte detection
US11104933B1 (en) * 2016-03-22 2021-08-31 Cleu Diagnostics, Llc Compositions and methods for determining the presence of active leukocyte cells using an electrochemical assay
JP2019513238A (ja) * 2016-03-30 2019-05-23 クオリザイム・ダイアグノスティクス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング・ウント・コムパニー・コマンディットゲゼルシャフトQualizyme Diagnostics Gmbh And Co. Kg 創傷における微生物感染の検出
JP6902416B2 (ja) * 2016-07-05 2021-07-14 ライオン株式会社 睡眠評価用マーカー及びその用途

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Also Published As

Publication number Publication date
HK15285A (en) 1985-03-15
SG79484G (en) 1985-08-16
CA1148073A (en) 1983-06-14
YU45527B (en) 1992-05-28
US4299917A (en) 1981-11-10
FI800444A (fi) 1980-08-15
JPS581920B2 (ja) 1983-01-13
DK63480A (da) 1980-08-15
HU182102B (en) 1983-12-28
RU1784097C (ru) 1992-12-23
AR223025A1 (es) 1981-07-15
FI69869C (fi) 1986-05-26
CS216523B2 (en) 1982-11-26
AU5535980A (en) 1981-01-15
DE2905531A1 (de) 1981-01-08
EP0014929B1 (de) 1982-01-06
DK161340C (da) 1991-12-02
EP0014929A1 (de) 1980-09-03
DE3060134D1 (en) 1982-02-25
PT70813A (de) 1980-03-01
DK161340B (da) 1991-06-24
DD149121A5 (de) 1981-06-24
PL221884A1 (da) 1980-11-03
FI69869B (fi) 1985-12-31
JPS55108300A (en) 1980-08-20
PL125796B1 (en) 1983-06-30
YU38680A (en) 1989-02-28
ES488402A0 (es) 1981-02-16
ES8102726A1 (es) 1981-02-16
YU212888A (en) 1990-04-30
ZA80765B (en) 1981-03-25
BR8000886A (pt) 1980-10-21
AU519912B2 (en) 1982-01-07

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