ATE533358T1 - Verfahren zum kontrollieren von schädlingen mittels rnai - Google Patents

Verfahren zum kontrollieren von schädlingen mittels rnai

Info

Publication number
ATE533358T1
ATE533358T1 AT06849359T AT06849359T ATE533358T1 AT E533358 T1 ATE533358 T1 AT E533358T1 AT 06849359 T AT06849359 T AT 06849359T AT 06849359 T AT06849359 T AT 06849359T AT E533358 T1 ATE533358 T1 AT E533358T1
Authority
AT
Austria
Prior art keywords
rnai
controlling pests
double stranded
stranded rna
rna molecules
Prior art date
Application number
AT06849359T
Other languages
English (en)
Inventor
Romaan Raemaekers
Pascale Feldmann
Geert Plaetinck
Irene Nooren
Els Bleu
Frederic Pecqueur
Laurent Kubler
Nicole Damme
Lies Degrave
Isabel Remory
Original Assignee
Devgen Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Devgen Nv filed Critical Devgen Nv
Application granted granted Critical
Publication of ATE533358T1 publication Critical patent/ATE533358T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/60—Isolated nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Insects & Arthropods (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Confectionery (AREA)
AT06849359T 2005-09-16 2006-09-18 Verfahren zum kontrollieren von schädlingen mittels rnai ATE533358T1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US71803405P 2005-09-16 2005-09-16
US75819106P 2006-01-12 2006-01-12
US77116006P 2006-02-07 2006-02-07
US83791006P 2006-08-16 2006-08-16
IBPCT/IB2006/003446 2006-09-15
PCT/IB2006/004008 WO2007083193A2 (en) 2005-09-16 2006-09-18 Methods for controlling pests using rnai

Publications (1)

Publication Number Publication Date
ATE533358T1 true ATE533358T1 (de) 2011-12-15

Family

ID=38287985

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06849359T ATE533358T1 (de) 2005-09-16 2006-09-18 Verfahren zum kontrollieren von schädlingen mittels rnai

Country Status (14)

Country Link
US (2) US8933042B2 (de)
EP (5) EP2269444A3 (de)
JP (2) JP5530632B2 (de)
CN (1) CN104357447A (de)
AT (1) ATE533358T1 (de)
AU (1) AU2006335978B2 (de)
BR (1) BRPI0615792A2 (de)
CA (1) CA2622671C (de)
ES (2) ES2568933T3 (de)
HU (1) HUE027349T2 (de)
MX (2) MX348513B (de)
PL (2) PL2270182T3 (de)
PT (1) PT2270181E (de)
WO (1) WO2007083193A2 (de)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7612194B2 (en) 2001-07-24 2009-11-03 Monsanto Technology Llc Nucleic acid sequences from Diabrotica virgifera virgifera LeConte and uses thereof
PT1818405E (pt) 2004-04-09 2015-10-20 Monsanto Technology Llc Composições e métodos para o controlo de infestações de plantas por insectos
US8404927B2 (en) 2004-12-21 2013-03-26 Monsanto Technology Llc Double-stranded RNA stabilized in planta
EP1907546A2 (de) * 2005-05-31 2008-04-09 Devgen N.V. Rnai zur bekämpfung von insekten und arachniden
SG166097A1 (en) 2005-09-16 2010-11-29 Monsanto Technology Llc Methods for genetic control of insect infestations in plants and compositions thereof
US8853489B2 (en) * 2005-09-16 2014-10-07 Devgen Nv Transgenic plant-based methods for plant pests using RNAi
CA2633576A1 (en) * 2006-01-12 2007-07-19 Devgen N.V. Dsrna as insect control agent
US8906876B2 (en) 2006-01-12 2014-12-09 Devgen Nv Methods for controlling pests using RNAi
EP1971688B1 (de) * 2006-01-12 2012-03-14 Devgen NV Dsrna als mittel zur insektenbekämpfung
EP2586866A1 (de) 2007-05-09 2013-05-01 Devgen NV Verfahren für nachhaltige Transgentranskription
US8097712B2 (en) 2007-11-07 2012-01-17 Beelogics Inc. Compositions for conferring tolerance to viral disease in social insects, and the use thereof
JP2009263362A (ja) * 2008-04-04 2009-11-12 Univ Of Tokushima 二本鎖ｒｎａを用いた害虫駆除剤
US8962584B2 (en) 2009-10-14 2015-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions for controlling Varroa mites in bees
US8524220B1 (en) 2010-02-09 2013-09-03 David Gordon Bermudes Protease inhibitor: protease sensitivity expression system composition and methods improving the therapeutic activity and specificity of proteins delivered by bacteria
US9597379B1 (en) 2010-02-09 2017-03-21 David Gordon Bermudes Protease inhibitor combination with therapeutic proteins including antibodies
US8771669B1 (en) 2010-02-09 2014-07-08 David Gordon Bermudes Immunization and/or treatment of parasites and infectious agents by live bacteria
PL2545182T4 (pl) 2010-03-08 2017-11-30 Monsanto Technology Llc Cząsteczki polinukeotydu do regulacji genów w roślinach
CA2797051C (en) 2010-04-23 2021-01-12 Novartis Ag Organic compositions to treat beta-enac-related diseases
CN103201385A (zh) * 2010-10-27 2013-07-10 德福根有限公司 下调昆虫害虫中的基因表达
CN102732554B (zh) 2011-03-31 2015-08-05 中国科学院上海生命科学研究院 一种提高植物抗虫能力的方法
EP2699685B1 (de) * 2011-04-20 2018-03-14 Devgen NV Herunterregulierung der genexpression bei insektenschädlingen
US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
MX377067B (es) 2011-09-13 2025-03-07 Monsanto Technology Llc Métodos y composiciones para el control de malezas.
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
AR091143A1 (es) 2012-05-24 2015-01-14 Seeds Ltd Ab Composiciones y metodos para silenciar la expresion genetica
US9688983B2 (en) 2012-12-20 2017-06-27 Dow Agrosciences Llc Nucleic acid molecules that confer resistance to coleopteran pests
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
CN105358695B (zh) 2013-01-01 2019-07-12 A.B.种子有限公司 将dsRNA引入植物种子以调节基因表达的方法
US9593339B1 (en) 2013-02-14 2017-03-14 David Gordon Bermudes Bacteria carrying bacteriophage and protease inhibitors for the treatment of disorders and methods of treatment
UA121846C2 (uk) 2013-03-13 2020-08-10 Монсанто Текнолоджи Ллс Спосіб та гербіцидна композиція для контролю видів рослини роду lolium
EP2971185A4 (de) 2013-03-13 2017-03-08 Monsanto Technology LLC Verfahren und zusammensetzungen zur unkrautbekämpfung
US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
MX359191B (es) 2013-07-19 2018-09-18 Monsanto Technology Llc Composiciones y métodos para controlar leptinotarsa.
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
UY35817A (es) 2013-11-04 2015-05-29 Us Agriculture ?composiciones y métodos para controlar infestaciones de plagas y parásitos de los artrópodos?.
UA119253C2 (uk) 2013-12-10 2019-05-27 Біолоджикс, Інк. Спосіб боротьби із вірусом у кліща varroa та у бджіл
EP3116303B1 (de) 2014-01-15 2020-07-22 Monsanto Technology LLC Verfahren und zusammensetzungen zur bekämpfung von unkraut unter verwendung von epsps-polynukleotiden
EP3420809A1 (de) 2014-04-01 2019-01-02 Monsanto Technology LLC Zusammensetzungen und verfahren zur bekämpfung von insektenbefall
AU2015280252A1 (en) 2014-06-23 2017-01-12 Monsanto Technology Llc Compositions and methods for regulating gene expression via RNA interference
WO2015200539A1 (en) 2014-06-25 2015-12-30 Monsanto Technology Llc Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
WO2016018887A1 (en) 2014-07-29 2016-02-04 Monsanto Technology Llc Compositions and methods for controlling insect pests
CN107148426A (zh) * 2014-10-13 2017-09-08 美国陶氏益农公司 赋予鞘翅目和半翅目害虫抗性的copi外被体alpha亚单位核酸分子
PL3256589T3 (pl) 2015-01-22 2022-02-21 Monsanto Technology Llc Kompozycje i sposoby kontrolowania leptinotarsa
MX2017012646A (es) 2015-04-17 2018-01-24 Dow Agrosciences Llc Moleculas que tienen utilidad plaguicida, e intermediarios, composiciones y procesos, relacionados con ellas.
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
EP3302053B1 (de) 2015-06-02 2021-03-17 Monsanto Technology LLC Zusammensetzungen und verfahren zur abgabe eines polynukleotids in eine pflanze
EP3302030A4 (de) 2015-06-03 2019-04-24 Monsanto Technology LLC Verfahren und zusammensetzungen zum einführen von nukleinsäuren in pflanzen
WO2017066041A2 (en) 2015-10-12 2017-04-20 Dow Agrosciences Llc Wupa nucleic acid molecules that confer resistance to coleopteran and hemipteran pests
AU2016371636A1 (en) 2015-12-18 2018-06-21 Dow Agrosciences Llc Ribosomal protein L40 (RPL40) nucleic acid molecules that confer resistance to coleopteran and hemipteran pests
WO2018013801A1 (en) 2016-07-13 2018-01-18 Indiana University Research And Technology Corporation Rnai insecticide materials and methods
WO2018046312A2 (en) * 2016-09-06 2018-03-15 Syngenta Participations Ag Improvements in or relating to gene silencing
KR20190095252A (ko) 2016-09-16 2019-08-14 페블 랩스 질병-전염성 모기의 생물학적 방제를 위한 파라트랜스제닉 시스템
KR102490246B1 (ko) 2016-10-12 2023-01-20 코르테바 애그리사이언스 엘엘씨 살충 유용성을 갖는 분자, 및 그와 관련된 중간체, 조성물, 및 방법
JP2020511472A (ja) * 2016-12-06 2020-04-16 ぺブル ラボ ユーエスエー インコーポレーテッド 植物病原体の生物的防除のための系および方法
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
EP3342780A1 (de) 2016-12-30 2018-07-04 Dow AgroSciences LLC Nukleinsäuremoleküle mit prä-mrna-verarbeitungsfaktor 8 (prp8) zur kontrolle von insektenschädlingen
JP7231551B2 (ja) * 2017-02-24 2023-03-01 フラグシップ パイオニアリング イノベーションズ ブイ，インコーポレーテッド 内部共生体を調節するための組成物及び関連方法
US10470468B2 (en) * 2017-04-11 2019-11-12 Mclaughlin Gormley King Company Mixtures of sabadilla oil and fungicides and uses thereof
AR113761A1 (es) 2017-10-18 2020-06-10 Syngenta Participations Ag Control de plagas de hemípteros utilizando moléculas de arn
WO2020016892A1 (en) 2018-07-18 2020-01-23 Plantarcbio Ltd. Compositions and methods for mitigating pest infestation with rhynchophorus ferrugineus
CN109370910B (zh) * 2018-08-03 2021-09-07 贵州省植物保护研究所 一种短帚霉及其用途
CN112770761A (zh) * 2018-09-13 2021-05-07 先正达农作物保护股份公司 使用rna分子控制植物有害生物
CN111849980B (zh) * 2020-06-30 2022-03-22 华南农业大学 一类抑制小菜蛾PPO激活的miRNAs及其应用
CN115786334B (zh) * 2022-07-27 2023-07-18 广东省农业科学院植物保护研究所 一种调控红火蚁生殖的小分子rna及其应用

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4876197A (en) 1983-02-22 1989-10-24 Chiron Corporation Eukaryotic regulatable transcription
JPS59205983A (ja) 1983-04-28 1984-11-21 ジエネツクス・コ−ポレイシヨン 異種遺伝子を原核微生物で発現させる方法
US4880734A (en) 1984-05-11 1989-11-14 Chiron Corporation Eukaryotic regulatable transcription
DE3888561T2 (de) 1987-03-23 1994-09-01 Zymogenetics Inc Hohe Proteinsyntheserate in Hefe.
EP0315447A3 (de) 1987-11-06 1990-07-18 Teijin Limited Verfahren zur immunologischen Bestimmung von humanem Protein S sowie Reagens und Kit dafür
US5614395A (en) 1988-03-08 1997-03-25 Ciba-Geigy Corporation Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
US5789214A (en) 1988-03-08 1998-08-04 Novartis Finance Corporation Method of inducing gene transcription in a plant
US5550318A (en) 1990-04-17 1996-08-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
JP3209744B2 (ja) 1990-01-22 2001-09-17 デカルブ・ジェネティクス・コーポレーション 結実能力のある遺伝子変換コーン
US5639949A (en) 1990-08-20 1997-06-17 Ciba-Geigy Corporation Genes for the synthesis of antipathogenic substances
US5633435A (en) 1990-08-31 1997-05-27 Monsanto Company Glyphosate-tolerant 5-enolpyruvylshikimate-3-phosphate synthases
ATE191931T1 (de) 1990-11-23 2000-05-15 Plant Genetic Systems Nv Verfahren zur transformation monokotyler pflanzen
US5593874A (en) 1992-03-19 1997-01-14 Monsanto Company Enhanced expression in plants
JPH08501928A (ja) 1992-07-02 1996-03-05 ハイブライドン インコーポレイテッド 治療剤としての自己安定化オリゴヌクレオチド
US6118047A (en) 1993-08-25 2000-09-12 Dekalb Genetic Corporation Anthranilate synthase gene and method of use thereof for conferring tryptophan overproduction
US7034009B2 (en) * 1995-10-26 2006-04-25 Sirna Therapeutics, Inc. Enzymatic nucleic acid-mediated treatment of ocular diseases or conditions related to levels of vascular endothelial growth factor receptor (VEGF-R)
US5693512A (en) 1996-03-01 1997-12-02 The Ohio State Research Foundation Method for transforming plant tissue by sonication
DE19631919C2 (de) 1996-08-07 1998-07-16 Deutsches Krebsforsch Anti-Sinn-RNA mit Sekundärstruktur
GB9827152D0 (en) 1998-07-03 1999-02-03 Devgen Nv Characterisation of gene function using double stranded rna inhibition
US6511824B1 (en) * 1999-03-17 2003-01-28 Exelixis, Inc. Nucleic acids and polypeptides of invertebrate TWIK channels and methods of use
US6703491B1 (en) * 1999-03-17 2004-03-09 Exelixis, Inc. Drosophila sequences
US6326193B1 (en) * 1999-11-05 2001-12-04 Cambria Biosciences, Llc Insect control agent
AU2047001A (en) * 1999-11-24 2001-06-04 Dna Plant Technology Corporation Methods of inhibiting plant parasitic nematodes and insect pests by expression of nematode and insect specific double-stranded rna in plants
AU2001245945A1 (en) * 2000-03-23 2001-10-03 Pe Corporation (Ny) Detection kits, such as nucleic acid arrays, for detecting the expression of 10,000 or more drosophila genes and uses thereof
GB0012233D0 (en) 2000-05-19 2000-07-12 Devgen Nv Vector constructs
US20020048814A1 (en) 2000-08-15 2002-04-25 Dna Plant Technology Corporation Methods of gene silencing using poly-dT sequences
US7109393B2 (en) 2000-08-15 2006-09-19 Mendel Biotechnology, Inc. Methods of gene silencing using inverted repeat sequences
EP1210875A1 (de) 2000-12-04 2002-06-05 Aventis CropScience GmbH Veränderung der Genexpression in Insekten durch Verwendung von doppelsträngiger RNA (dsRNA)
AUPR621501A0 (en) * 2001-07-06 2001-08-02 Commonwealth Scientific And Industrial Research Organisation Delivery of ds rna
AU2002312270A1 (en) 2002-06-03 2004-01-19 Harbor Steel And Supply Corporation Carrousel file
WO2004001000A2 (en) * 2002-06-21 2003-12-31 Monsanto Technology Llc Intron double stranded rna constructs and uses thereof
US20040053289A1 (en) * 2002-09-09 2004-03-18 The Regents Of The University Of California Short interfering nucleic acid hybrids and methods thereof
US8090542B2 (en) * 2002-11-14 2012-01-03 Dharmacon Inc. Functional and hyperfunctional siRNA
US7655785B1 (en) * 2002-11-14 2010-02-02 Rosetta Genomics Ltd. Bioinformatically detectable group of novel regulatory oligonucleotides and uses thereof
IL157538A0 (en) * 2003-08-21 2004-03-28 Bar Ilan Res & Dev Company Ltd Plant resistant to cytoplasm-feeding parasites
WO2005026359A2 (en) * 2003-09-15 2005-03-24 Cenix Bioscience Gmbh The use of eukaryotic genes affecting spindle formation or microtubule function during cell division for diagnosis and treatment of proliferative diseases
ATE526407T1 (de) * 2003-11-17 2011-10-15 Commw Scient Ind Res Org Insektenresistenz durch inhibierung von genexpression
WO2005071091A1 (fr) * 2003-12-23 2005-08-04 Bayer Cropscience Sa Methode pour modifier l'expression genique d'un champignon phytopathogene
PT1818405E (pt) * 2004-04-09 2015-10-20 Monsanto Technology Llc Composições e métodos para o controlo de infestações de plantas por insectos
US7576261B2 (en) 2004-10-13 2009-08-18 University Of Georgia Research Foundation, Inc. Nematode resistant transgenic plants
WO2006045590A2 (en) 2004-10-25 2006-05-04 Devgen N.V. Multidomain rna molecules comprising at least one aptamer for delivering double stranded rna to pest organisms
WO2006046148A2 (en) 2004-10-25 2006-05-04 Devgen Nv Rna constructs
US8853489B2 (en) * 2005-09-16 2014-10-07 Devgen Nv Transgenic plant-based methods for plant pests using RNAi
SG166097A1 (en) * 2005-09-16 2010-11-29 Monsanto Technology Llc Methods for genetic control of insect infestations in plants and compositions thereof
CN101384721A (zh) * 2006-02-13 2009-03-11 孟山都技术有限公司 选择和稳定dsRNA构建体

Also Published As

Publication number Publication date
CA2622671C (en) 2020-12-22
EP1934357A2 (de) 2008-06-25
EP2270181B1 (de) 2015-10-21
WO2007083193A3 (en) 2008-01-24
JP2014113156A (ja) 2014-06-26
US8933042B2 (en) 2015-01-13
MX348513B (es) 2017-06-16
EP2270182A3 (de) 2012-04-18
WO2007083193A2 (en) 2007-07-26
BRPI0615792A2 (pt) 2009-06-16
EP2270182B1 (de) 2016-02-10
JP5530632B2 (ja) 2014-06-25
JP2009508482A (ja) 2009-03-05
US9982258B2 (en) 2018-05-29
EP2270181A3 (de) 2012-04-04
MX339645B (es) 2016-06-03
US20150065557A1 (en) 2015-03-05
US20090306189A1 (en) 2009-12-10
EP2269444A3 (de) 2012-04-04
ES2568933T3 (es) 2016-05-05
EP2270181A2 (de) 2011-01-05
EP2281876A3 (de) 2012-04-11
ES2557513T3 (es) 2016-01-26
EP2281876A2 (de) 2011-02-09
HUE027349T2 (en) 2016-09-28
AU2006335978B2 (en) 2014-02-20
EP2270182A2 (de) 2011-01-05
EP1934357B1 (de) 2011-11-16
CN104357447A (zh) 2015-02-18
CA2622671A1 (en) 2007-07-26
PT2270181E (pt) 2016-01-26
PL2270182T3 (pl) 2016-07-29
AU2006335978A1 (en) 2007-07-26
US20180142237A9 (en) 2018-05-24
EP2269444A2 (de) 2011-01-05
PL2270181T3 (pl) 2016-04-29

Similar Documents

Publication Publication Date Title
ATE533358T1 (de) Verfahren zum kontrollieren von schädlingen mittels rnai
ATE549409T1 (de) Dsrna als mittel zur insektenbekämpfung
EP2330207A3 (de) Transgene, auf Pflanzen basierende Verfahren zur Bekämpfung von Pflanzenschädlingen unter Verwendung von RNAi
EP2295584A3 (de) Transgene, auf Pflanzen basierende Verfahren zur Bekämpfung von Pflanzenschädlingen unter Verwendung von RNAi
EP2377939A3 (de) Verfahren auf Basis transgener Pflanzen für Pflanzenschädlinge mit RNAi
UA111934C2 (uk) ТРАНСГЕННА РОСЛИНА, ЩО МІСТИТЬ ДНК, ЯКА КОДУЄ ІНСЕКТИЦИДНИЙ БІЛОК Vip3Ab, І ДНК, ЯКА КОДУЄ ІНСЕКТИЦИДНИЙ БІЛОК Cry1Fa, СТІЙКА ДО ЛУСКОКРИЛИХ ШКІДНИКІВ
IL185253A (en) Cytoquenols are preserved in spirocetal, a process for their preparation, preparations containing them and methods for their use in the control of pests
EP2085419A4 (de) Verfahren zur herstellung von modifiziertem polymer, nach dem verfahren erhaltenes modifiziertes polymer und kautschukzusammensetzung damit
WO2012055982A3 (en) Down-regulating gene expression in insect pests
HRP20130750T1 (hr) Postupak identifikacije molekula za vezanje koje mogu neutralizirati virus bjesnoä†e
NO20081883L (no) Modulasjon av glukokortikoidreseptorekspresjon
EP2599872A3 (de) Pflanzen mit verbesserten Ertragseigenschaften und Verfahren zu ihrer Herstellung
EA200800869A1 (ru) Модуляция экспрессии рецептора глюкагона
ATE454458T1 (de) Pflanzen mit verbesserten wachstumseigenschaften und verfahren zu deren herstellung
DE602005025669D1 (de) Pflanzen mit veränderten wachstumseigenschaften und verfahren zu deren herstellung
DE602006009901D1 (de) Verfahren zur herstellung von 7-ethyl-10-hydroxycamptothecin
DE602008002140D1 (de) Verfahren zum Erhalten von natürlichem Astaxanthin aus Eiern und Gonaden aus Schnecken
ATE469974T1 (de) Pflanzen mit gesteigertem saatertrag und verfahren zu deren herstellung
ATE491797T1 (de) Pflanzen mit erhöhtem ertrag und verfahren zur herstellung davon
AR062554A1 (es) Metodo para controlar hongos daninos
ATE538098T1 (de) Verfahren zum herstellen von 5-fluor-1,3-dialkyl- 1h-pyrazol-4-carbonsäurechloriden
WO2010078899A3 (de) Verfahren zur bekämpfung resistenter tierischer schädlinge
TH134782A (th) วิธีเพื่อแสดงเอกลักษณ์องค์ประกอบที่ปรับเปลี่ยนการแสดงออกของยีนและโปรตีนไวลต์ไทป์ในเซลล์พืช
ATE440136T1 (de) Verfahren für die kontinuierliche zielgerichtete evolution von proteinen in vivo
WO2008074851A3 (en) Method for inhibiting the expression of endogenous erythropoietin (epo)