ATE528320T1 - Erzeugung von oberflächenbeschichtungsdivergenz - Google Patents

Erzeugung von oberflächenbeschichtungsdivergenz

Info

Publication number
ATE528320T1
ATE528320T1 AT03718551T AT03718551T ATE528320T1 AT E528320 T1 ATE528320 T1 AT E528320T1 AT 03718551 T AT03718551 T AT 03718551T AT 03718551 T AT03718551 T AT 03718551T AT E528320 T1 ATE528320 T1 AT E528320T1
Authority
AT
Austria
Prior art keywords
copolymer
substrate
constituent
synthon
functional group
Prior art date
Application number
AT03718551T
Other languages
English (en)
Inventor
Michael Barden
Peter Kambouris
Original Assignee
Bio Layer Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Layer Pty Ltd filed Critical Bio Layer Pty Ltd
Application granted granted Critical
Publication of ATE528320T1 publication Critical patent/ATE528320T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/18—Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0081—After-treatment of organic or inorganic membranes
    • B01D67/0093—Chemical modification
    • B01D67/00931—Chemical modification by introduction of specific groups after membrane formation, e.g. by grafting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/30—Polyalkenyl halides
    • B01D71/32—Polyalkenyl halides containing fluorine atoms
    • B01D71/34—Polyvinylidene fluoride
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F259/00—Macromolecular compounds obtained by polymerising monomers on to polymers of halogen containing monomers as defined in group C08F14/00
    • C08F259/08—Macromolecular compounds obtained by polymerising monomers on to polymers of halogen containing monomers as defined in group C08F14/00 on to polymers containing fluorine
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F261/00—Macromolecular compounds obtained by polymerising monomers on to polymers of oxygen-containing monomers as defined in group C08F16/00
    • C08F261/06—Macromolecular compounds obtained by polymerising monomers on to polymers of oxygen-containing monomers as defined in group C08F16/00 on to polymers of unsaturated ethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F291/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • C08F293/005—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L51/00—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C08L51/003—Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D151/00—Coating compositions based on graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers
    • C09D151/003—Coating compositions based on graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers grafted on to macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D153/00—Coating compositions based on block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
    • C40B50/18—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support using a particular method of attachment to the solid support
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/38—Graft polymerization
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315—Microtiter plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/005—Beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/0061—The surface being organic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00623—Immobilisation or binding
    • B01J2219/00626—Covalent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632—Introduction of reactive groups to the surface
    • B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00639—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
    • B01J2219/00641—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium the porous medium being continuous, e.g. porous oxide substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00736—Non-biologic macromolecules, e.g. polymeric compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Structural Engineering (AREA)
  • Wood Science & Technology (AREA)
  • Materials Engineering (AREA)
  • Water Supply & Treatment (AREA)
  • Manufacturing & Machinery (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Transplantation (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Paints Or Removers (AREA)
AT03718551T 2002-05-10 2003-05-09 Erzeugung von oberflächenbeschichtungsdivergenz ATE528320T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37996602P 2002-05-10 2002-05-10
PCT/AU2003/000566 WO2003095494A1 (en) 2002-05-10 2003-05-09 Generation of surface coating diversity

Publications (1)

Publication Number Publication Date
ATE528320T1 true ATE528320T1 (de) 2011-10-15

Family

ID=29420591

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03718551T ATE528320T1 (de) 2002-05-10 2003-05-09 Erzeugung von oberflächenbeschichtungsdivergenz

Country Status (6)

Country Link
US (1) US8273403B2 (de)
EP (1) EP1534755B1 (de)
AT (1) ATE528320T1 (de)
AU (1) AU2003222676B2 (de)
ES (1) ES2373714T3 (de)
WO (1) WO2003095494A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE528320T1 (de) 2002-05-10 2011-10-15 Bio Layer Pty Ltd Erzeugung von oberflächenbeschichtungsdivergenz
WO2006002472A1 (en) 2004-07-02 2006-01-12 Bio-Layer Pty Ltd Use of metal complexes
US8795782B2 (en) 2006-08-18 2014-08-05 Commonwealth Scientific And Industrial Research Organisation Polymeric coatings and methods for forming them
WO2008019450A1 (en) * 2006-08-18 2008-02-21 Commonwealth Scientific And Industrial Research Organisation Polymeric coatings and methods for forming them
US20100279422A1 (en) * 2006-08-21 2010-11-04 Cmed Technologies Ltd. Method of surface plasmon resonance (spr) technology to detect genomic disorders for prenatal diagnosis
US20100086920A1 (en) * 2006-09-18 2010-04-08 Cmed Technologies Ltd. Method to assess cancer susceptibility and differential diagnosis of metastases of unknown primary tumors
US8153445B2 (en) * 2006-09-19 2012-04-10 Cmed Technologies Ltd. Method for screening of infectious agents in blood
WO2008036474A2 (en) * 2006-09-21 2008-03-27 Cmed Technologies Ltd. A method to detect tumor markers and diagnosis of undifferenciated tumors
US20100021971A1 (en) * 2006-09-21 2010-01-28 Cmed Technologies Ltd. Method to remove repetitive sequences from human dna
WO2008085554A2 (en) * 2006-09-25 2008-07-17 Cmed Technologies Ltd. A method to detect virus related immunologigal markers for the diagnosis of hepatitis b virus infection
WO2008066982A2 (en) * 2006-09-25 2008-06-05 Cmed Technologies Ltd. A method of surface plasmon resonance (spr) technology to detect genomic aberrations in patients with chronic lymphocytic leukemia
US20100041018A1 (en) * 2006-09-25 2010-02-18 Cmed Technologies Ltd. Method to detect virus related immunological markers for the diagnosis of hepatitis c virus infection
GB2455929B (en) * 2006-09-25 2011-08-31 Cmed Technologies Limited A method for the identification of human immunodeficiency virus related antibodies in blood
US8119350B2 (en) * 2006-09-25 2012-02-21 Cmed Technologies Ltd Method of surface plasmon resonance (SPR) to detect genomic aberrations in patients with multiple myeloma
WO2008094312A2 (en) * 2006-09-25 2008-08-07 Cmed Technologies Ltd. A method of surface plasmon resonance (spr) technology to detect genomic disorders for postnatal diagnosis
US20100086937A1 (en) * 2006-09-27 2010-04-08 Cmed Technologies Ltd. method to detect treponema pallidum immunological markers for the diagnosis of syphilis
WO2008066997A2 (en) * 2006-09-27 2008-06-05 Cmed Technologies Ltd. A method for quantitative measurement of cardiac biochemical markers
WO2008067003A2 (en) * 2006-09-27 2008-06-05 Cmed Technologies Ltd. A method to detect virus related immunological markers for the diagnosis of respiratory tract infections
WO2008067008A2 (en) * 2006-09-27 2008-06-05 Cmed Technologies Ltd. A method for the quantitative evaluation of sex hormones in a serum sample
WO2008066994A2 (en) * 2006-09-27 2008-06-05 Cmed Technologies Ltd. Application of surface plasmon resonance technology to maternal serum screening for congenital birth defects
US8110409B2 (en) * 2006-09-27 2012-02-07 Cmed Technologies Ltd. Method to measure serum biomarkers for the diagnosis of liver fibrosis
GB2456690B (en) * 2006-09-28 2012-01-25 Cytotrend Biotech Engineering Ltd Usa Inc A method for quantitative detection of diabetes related immunological markers
WO2008067007A2 (en) * 2006-09-28 2008-06-05 Cmed Technologies Ltd. A method for quantitative measurement of thyroid homrones and related antibodies in a serum sample
WO2009045216A1 (en) 2007-10-04 2009-04-09 Cmed Technologies Ltd. Application of surface plasmon resonance technology for detecting and genotyping hpv
US10077376B2 (en) 2014-01-31 2018-09-18 Siemens Healthcare Diagnostics Inc. Paramagnetic supports for use as assay reagents
US9548188B2 (en) 2014-07-30 2017-01-17 Lam Research Corporation Method of conditioning vacuum chamber of semiconductor substrate processing apparatus
CN120795059A (zh) 2018-08-27 2025-10-17 瑞泽恩制药公司 拉曼光谱在下游纯化中的应用
EP4497494A1 (de) * 2023-07-24 2025-01-29 Gambro Lundia AB Membranen enthaltend sma für die immobilisierung funktioneller moleküle
AU2024316772A1 (en) * 2023-08-03 2026-03-12 Seer, Inc. Brush polymer macromolecule structures and methods for detecting biomolecules

Family Cites Families (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE561742A (de) 1956-10-18
GB935013A (en) 1959-05-27 1963-08-21 Bx Plastics Ltd Process for manufacturing graft copolymers of polyolefines and styrene
GB1006622A (en) 1962-07-18 1965-10-06 Toyo Rayon Co Ltd Method of improving the surface properties of polypropylene film
US3362942A (en) 1965-02-23 1968-01-09 Du Pont Process for polymerizing and curing methyl methacrylate monomer-polymer sirups in thepresence of metal salts of hemi-peresters of maleic acid
US3849172A (en) 1968-08-23 1974-11-19 Uniroyal Inc Electrolessly plateable polymeric composition
IL49685A (en) 1976-05-31 1978-10-31 Technion Res & Dev Foundation Specific binding assay method for determining the concentration of materials and reagent means therefor
JPS54160474A (en) 1978-06-09 1979-12-19 Kansai Paint Co Ltd Modification of surface of high polymer base
NZ199916A (en) 1981-03-11 1985-07-12 Unilever Plc Low density polymeric block material for use as carrier for included liquids
JPS6214905A (ja) 1985-07-15 1987-01-23 Fuji Photo Film Co Ltd 微孔性膜の製造方法
US4771110A (en) 1986-02-04 1988-09-13 Air Products And Chemicals, Inc. Polymeric materials having controlled physical properties and processes for obtaining these
US4799931A (en) 1986-05-14 1989-01-24 Lindstrom Richard L Intracorneal lens
US5108776A (en) 1987-04-10 1992-04-28 University Of Florida Ocular implants and methods for their manufacture
GB8709688D0 (en) 1987-04-24 1987-05-28 Unilever Plc Porous material
US5244799A (en) 1987-05-20 1993-09-14 Anderson David M Preparation of a polymeric hydrogel containing micropores and macropores for use as a cell culture substrate
US5238613A (en) 1987-05-20 1993-08-24 Anderson David M Microporous materials
NL8702448A (nl) 1987-10-14 1989-05-01 Dyneema Vof Oppervlaktebehandeling van polyolefinevoorwerpen.
FR2629916B1 (fr) 1988-04-08 1992-09-04 Hoechst Behring Applic Pharmac Support solide pour diagnostic immunologique, son procede de traitement et application au diagnostic immunologique
JPH01275639A (ja) 1988-04-28 1989-11-06 Agency Of Ind Science & Technol 表面改質方法
JP2611338B2 (ja) 1988-06-20 1997-05-21 日本ビクター株式会社 導電性高分子材料
DE68914843T2 (de) 1988-09-01 1994-11-10 Risoe Forskningscenter Peptid-synthese und fester träger zur verwendung dabei.
WO1990007575A1 (en) 1988-12-30 1990-07-12 Anderson David M Stabilized microporous materials and hydrogel materials
EP0412154B1 (de) 1989-02-23 1995-06-14 Chemfab Corporation Polyimid und fluorpolymer enthaltende filme und schichtstoffe
US5080924A (en) 1989-04-24 1992-01-14 Drexel University Method of making biocompatible, surface modified materials
US6346413B1 (en) * 1989-06-07 2002-02-12 Affymetrix, Inc. Polymer arrays
JPH0365341A (ja) 1989-08-04 1991-03-20 Mitsui Petrochem Ind Ltd 積層体
GB8925302D0 (en) 1989-11-09 1989-12-28 Nat Res Dev Gas-permeable contact lens
JP3102039B2 (ja) 1990-03-14 2000-10-23 住友化学工業株式会社 熱可塑性樹脂成形品の表面処理方法および塗装方法
DE69119688T2 (de) 1990-10-10 1997-01-16 Minnesota Mining & Mfg Pfropfcopolymere und Pfropfcopolymer-/Protein- Zusammensetzungen
US5130343A (en) 1991-03-13 1992-07-14 Cornell Research Foundation, Inc. Process for producing uniform macroporous polymer beads
US5344701A (en) 1992-06-09 1994-09-06 Minnesota Mining And Manufacturing Company Porous supports having azlactone-functional surfaces
US5583211A (en) 1992-10-29 1996-12-10 Beckman Instruments, Inc. Surface activated organic polymers useful for location - specific attachment of nucleic acids, peptides, proteins and oligosaccharides
US5384265A (en) 1993-03-26 1995-01-24 Geo-Centers, Inc. Biomolecules bound to catalytic inorganic particles, immunoassays using the same
DK72493D0 (da) * 1993-06-18 1993-06-18 Risoe Forskningscenter Solid supports for use in peptide synthesis and assays
WO1995009176A1 (en) * 1993-09-28 1995-04-06 Beckman Instruments, Inc. Biopolymer synthesis utilizing surface activated, organic polymers
US5922545A (en) 1993-10-29 1999-07-13 Affymax Technologies N.V. In vitro peptide and antibody display libraries
DE69531640T2 (de) 1994-03-04 2004-02-19 Pall Corp. Trennung einer Zellsuspension in ein Zellmaterial und ein Filtrat
US5683800A (en) 1994-10-28 1997-11-04 The Dow Chemical Company Surface-modified post-crosslinked adsorbents and a process for making the surface modified post-crosslinked adsorbents
JPH08259716A (ja) 1995-03-22 1996-10-08 Japan Atom Energy Res Inst 脂肪族アミンとの光照射によるフッ素系高分子の表面改質方法
WO1997002310A1 (en) 1995-06-30 1997-01-23 Commonwealth Scientific And Industrial Research Organisation Improved surface treatment of polymers
JP2776340B2 (ja) 1995-11-08 1998-07-16 日本電気株式会社 指紋特徴抽出装置
US5807937A (en) 1995-11-15 1998-09-15 Carnegie Mellon University Processes based on atom (or group) transfer radical polymerization and novel (co) polymers having useful structures and properties
US5691431A (en) 1996-01-18 1997-11-25 Exxon Chemical Patents Inc. Cationic polymerization catalyzed by lewis acid catalysts supported on porous polymer substrate
EP0889925B1 (de) 1996-03-27 2004-06-02 Novartis AG Verfahren zur herstellung von porösen polymeren unter anwendung eines porenbildendes agens
ATE207082T1 (de) 1996-06-12 2001-11-15 Univ Warwick Polymerisation-katalysator und -verfahren
AU739391B2 (en) 1996-07-03 2001-10-11 President And Fellows Of Harvard College Oligonucleotide linker and techniques involving immobilized and linked oligonucleotides
US5789487A (en) 1996-07-10 1998-08-04 Carnegie-Mellon University Preparation of novel homo- and copolymers using atom transfer radical polymerization
US6136274A (en) 1996-10-07 2000-10-24 Irori Matrices with memories in automated drug discovery and units therefor
FR2754535A1 (fr) 1996-10-16 1998-04-17 Atochem Elf Sa Polymeres greffes a viscosite controlee
DE59800682D1 (de) 1997-04-14 2001-06-13 Degussa Verfahren zur Modifizierung der Oberfläche von Polymersubstraten durch Pfropfpolymerisation
WO1998054665A1 (en) 1997-06-02 1998-12-03 The Johns Hopkins University Computer method utilizing free energy calculations for ligand design and the prediction of binding targets
US6013459A (en) 1997-06-12 2000-01-11 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
GB9725455D0 (en) 1997-12-02 1998-01-28 Univ Warwick Supported polymerisation catalyst
US5976813A (en) 1997-12-12 1999-11-02 Abbott Laboratories Continuous format high throughput screening
US5932102A (en) 1998-01-12 1999-08-03 Schering Corporation Immobilized metal, affinity chromatography
JP3608941B2 (ja) 1998-04-03 2005-01-12 株式会社ユポ・コーポレーション 熱可塑性樹脂フィルムの表面処理方法
AU752942B2 (en) 1998-04-13 2002-10-03 Massachusetts Institute Of Technology Comb copolymers for regulating cell-surface interactions
CA2277372C (en) 1998-07-13 2011-03-15 Tran Quang Minh Affinity immobilised metal resins
US6406921B1 (en) * 1998-07-14 2002-06-18 Zyomyx, Incorporated Protein arrays for high-throughput screening
DE19838241A1 (de) 1998-08-22 2000-02-24 Henrik Boettcher Verfahren zur chemischen Modifizierung von Feststoffoberflächen durch "lebende"/kontrollierte Radikalreaktionen
AU5855699A (en) 1998-08-28 2000-03-21 Jerini Biotools Gmbh Method for producing polymeric solid phase supporting materials
CA2343115A1 (en) 1998-09-15 2000-03-23 National Power Plc Water based grafting
CA2249955A1 (en) 1998-10-13 2000-04-13 James E. Guillet Graft polymerization process
WO2000078740A1 (en) 1999-06-23 2000-12-28 Warner-Lambert Company Solid-supported initiators and functional polymers for use in organic synthesis and combinatorial chemistry
AT408227B (de) 1999-07-22 2001-09-25 Wolfgang Dr Kern Verfahren zur modifizierung von polymeroberflächen
GB9923347D0 (en) * 1999-10-05 1999-12-08 Univ Manchester Processing apparatus and method
DE60016449T2 (de) 1999-10-27 2005-12-08 Novartis Ag Beschichtungsverfahren
JP4431233B2 (ja) 1999-11-30 2010-03-10 テルモ株式会社 ハニカム構造体およびその調製方法、ならびにその構造体を用いたフィルムおよび細胞培養基材
FR2805268B1 (fr) 2000-02-23 2005-03-25 Atofina Polymeres thermoreversibles a fonctions mitroxyde
JP2001261758A (ja) 2000-03-17 2001-09-26 Kawamura Inst Of Chem Res 共連続構造を有する樹脂複合体及びその製造方法
US6562411B2 (en) 2000-05-24 2003-05-13 Agfa-Gevaert Combinatorial coating for developing novel materials
AUPQ859000A0 (en) 2000-07-06 2000-07-27 Commonwealth Scientific And Industrial Research Organisation Apparatus for surface engineering
TW513485B (en) 2000-07-10 2002-12-11 Ind Tech Res Inst On-spot hydrophilic enhanced slide and preparation thereof
DE10056658C1 (de) * 2000-11-15 2002-07-04 Steinert Gmbh Elektromagnetbau Vorrichtung und Verfahren zum Separieren von einer Metalle enthaltenden Feststoffmischung
JP2002155228A (ja) 2000-11-24 2002-05-28 Dainippon Ink & Chem Inc ポリオレフィンフィルム用印刷インキ
AUPR224600A0 (en) 2000-12-21 2001-01-25 Polymerat Pty Ltd Novel polymers
AUPR404801A0 (en) 2001-03-28 2001-04-26 Polymerat Pty Ltd A method of polymerization
US20030003223A1 (en) 2001-04-07 2003-01-02 The Regents Of The University Of California Methods and compositions for binding histidine-containing proteins to substrates
US6942802B2 (en) 2001-04-13 2005-09-13 Wyeth Holdings Corporation Removal of bacterial endotoxin in a protein solution by immobilized metal affinity chromatography
ATE394412T1 (de) 2001-06-21 2008-05-15 Clontech Lab Inc Wasserlösliche polymere zusammensetzungen mit affinität für metallionen und verfahren zu deren anwendung
ES2322338T3 (es) 2001-11-12 2009-06-19 Novo Nordisk A/S Purificacion de peptidos por medio de cromatografia de afinidad con iones metalicos.
US20030215877A1 (en) 2002-04-04 2003-11-20 California Institute Of Technology Directed protein docking algorithm
JP4273311B2 (ja) 2002-04-26 2009-06-03 株式会社シノテスト 試料中の測定対象物質の測定方法及び測定試薬
ATE528320T1 (de) 2002-05-10 2011-10-15 Bio Layer Pty Ltd Erzeugung von oberflächenbeschichtungsdivergenz
JP4092394B2 (ja) 2002-05-23 2008-05-28 独立行政法人産業技術総合研究所 核酸選別用センサーチップ
JP3839359B2 (ja) 2002-06-14 2006-11-01 東洋鋼鈑株式会社 化学修飾を施した固体支持体およびその用途
FR2842826B1 (fr) 2002-07-25 2006-01-20 Centre Nat Rech Scient Procede de fabrication de puces biologiques
AU2003287144A1 (en) 2002-12-18 2004-07-09 Astrazeneca Ab Inositol phosphate detection assays
AU2004296412B2 (en) 2003-12-12 2011-03-10 Anteo Technologies Pty Ltd A method for designing surfaces
JP4253634B2 (ja) 2004-11-30 2009-04-15 富士フイルム株式会社 デジタルカメラ
GB0620406D0 (en) 2006-10-13 2006-11-22 Glaxo Group Ltd Novel compounds

Also Published As

Publication number Publication date
US8273403B2 (en) 2012-09-25
EP1534755A1 (de) 2005-06-01
ES2373714T3 (es) 2012-02-08
AU2003222676B2 (en) 2009-04-23
AU2003222676A1 (en) 2003-11-11
EP1534755A4 (de) 2005-08-17
EP1534755B1 (de) 2011-10-12
WO2003095494A1 (en) 2003-11-20
US20060083858A1 (en) 2006-04-20

Similar Documents

Publication Publication Date Title
ATE410198T1 (de) Immobilisierte bioaktive hydrogel matrizen für oberflächenbeschichtungen
DE60306186D1 (de) Verfahren und system zur anordnung von dienste in einer webdienstarchitektur
EP1501224A3 (de) Komplexes orthogonales Spreizverfahren für Mehrkanäle und zugehörende Vorrichtung
WO2000033084A3 (en) Arrays of organic compounds attached to surfaces
AR017377A1 (es) Polieteraminas termicamente estables, proceso para obtener dichas polieteraminas, estructuras laminares que comprenden una o mas capas de dichasestructuras y solventes y composiciones de recubrimiento que comprenden dichas polieteraminas
WO2003013055A8 (en) Methods and apparatus for storage and processing of routing information
CA2221517A1 (en) Synthesis of n-substituted oligomers
WO2004043588A3 (en) Production of polymeric microarrays
DK1487591T3 (da) Fremstilling af overtrækninger ved plasmapolymerisering
MX9709501A (es) Proceso para transicionar entre catalizadores de polimerizacion incompatibles.
WO2000051077A3 (en) Method and apparatus for evolving configuration bitstreams
EP0899894B1 (de) Intelligenter Antennenempfänger und Signalempfangsverfahren
WO2004001506A3 (en) Antireflective coatings for high-resolution photolithographic synthesis of dna array
SE9601506D0 (sv) DNA sequence for starch brancing enzyme II of potato
EA200500911A1 (ru) Планшеты и системы для крупномасштабной электропорации и способы их применения
ATE307944T1 (de) Coldboxblechmantel
TW200508631A (en) Semiconductor testing apparatus and controlling method thereof
DE60336208D1 (de) Belichtungsmasken, und methoden zur herstellung von masken
DK1434632T3 (da) Legetöjsfartöj omfattende fleksible elementer
WO2006004877A3 (en) Ewald summation method for molecular simulation
ES2135905T3 (es) Polimeros para revestimientos antiensuciamiento y un procedimiento para su preparacion.
WO2006003174A3 (fr) Systeme de protection sonore deployable
CA2486780A1 (en) A method and system for network wide fault isolation in an optical network
Tamamura et al. Topochemical exploration of potent compounds using retro-enantiomer libraries of cyclic pentapeptides
JP2020536493A5 (de)

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties