ATE512989T1 - Verfahren zur herstellung von scdb-bibliotheken - Google Patents

Verfahren zur herstellung von scdb-bibliotheken

Info

Publication number
ATE512989T1
ATE512989T1 AT03717592T AT03717592T ATE512989T1 AT E512989 T1 ATE512989 T1 AT E512989T1 AT 03717592 T AT03717592 T AT 03717592T AT 03717592 T AT03717592 T AT 03717592T AT E512989 T1 ATE512989 T1 AT E512989T1
Authority
AT
Austria
Prior art keywords
libraries
scdb
producing
antigen
constructed
Prior art date
Application number
AT03717592T
Other languages
English (en)
Inventor
Tetsuo Kojima
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE512989T1 publication Critical patent/ATE512989T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/468Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1093General methods of preparing gene libraries, not provided for in other subgroups
AT03717592T 2002-04-15 2003-04-15 Verfahren zur herstellung von scdb-bibliotheken ATE512989T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002112369 2002-04-15
PCT/JP2003/004773 WO2003087163A1 (fr) 2002-04-15 2003-04-15 Procede d'elaboration d'une banque scdb

Publications (1)

Publication Number Publication Date
ATE512989T1 true ATE512989T1 (de) 2011-07-15

Family

ID=29243316

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03717592T ATE512989T1 (de) 2002-04-15 2003-04-15 Verfahren zur herstellung von scdb-bibliotheken

Country Status (6)

Country Link
US (1) US8030461B2 (de)
EP (1) EP1500665B1 (de)
JP (1) JP4386741B2 (de)
AT (1) ATE512989T1 (de)
AU (1) AU2003227504A1 (de)
WO (1) WO2003087163A1 (de)

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JP5057967B2 (ja) 2005-03-31 2012-10-24 中外製薬株式会社 sc(Fv)2構造異性体
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WO2007114319A1 (ja) 2006-03-31 2007-10-11 Chugai Seiyaku Kabushiki Kaisha 抗体の血中動態を制御する方法
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BRPI0714209A2 (pt) * 2006-07-13 2014-06-24 Chugai Pharmaceutical Co Ltd Induzidor de morte celular
JP5334319B2 (ja) 2007-09-26 2013-11-06 中外製薬株式会社 Cdrのアミノ酸置換により抗体の等電点を改変する方法
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ES2660151T3 (es) 2010-11-17 2018-03-21 Chugai Seiyaku Kabushiki Kaisha Molécula de unión a antígeno multiespecífica que tiene función alternativa a la función del factor VIII de coagulación sanguínea
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Also Published As

Publication number Publication date
US20070087381A1 (en) 2007-04-19
WO2003087163A1 (fr) 2003-10-23
EP1500665A1 (de) 2005-01-26
US8030461B2 (en) 2011-10-04
AU2003227504A1 (en) 2003-10-27
EP1500665A4 (de) 2006-05-24
EP1500665B1 (de) 2011-06-15
JPWO2003087163A1 (ja) 2005-08-18
JP4386741B2 (ja) 2009-12-16

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